KR960020996A - Toothpaste composition for inhibiting and preventing tooth decay and manufacturing method thereof - Google Patents

Toothpaste composition for inhibiting and preventing tooth decay and manufacturing method thereof Download PDF

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Publication number
KR960020996A
KR960020996A KR1019940038494A KR19940038494A KR960020996A KR 960020996 A KR960020996 A KR 960020996A KR 1019940038494 A KR1019940038494 A KR 1019940038494A KR 19940038494 A KR19940038494 A KR 19940038494A KR 960020996 A KR960020996 A KR 960020996A
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KR
South Korea
Prior art keywords
toothpaste
bacteriocin
composition
toothpaste composition
inhibiting
Prior art date
Application number
KR1019940038494A
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Korean (ko)
Inventor
이상준
오세종
김상교
백영진
Original Assignee
이은선
한국야쿠르트유업 주식회사
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Priority to KR1019940038494A priority Critical patent/KR960020996A/en
Publication of KR960020996A publication Critical patent/KR960020996A/en

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Abstract

1. 청구범위에 기재된 발명이 속한 기술분야1. TECHNICAL FIELD OF THE INVENTION

본 발명은 충치 억제 및 예방용 치약조성물 및 그 제조방법에 관한 것이다.The present invention relates to a toothpaste composition for inhibiting and preventing tooth decay and a method of manufacturing the same.

2. 발명의 해결하려고 하는 기술적 과제2. Technical problem to be solved

구강내의 충치균을 제거하기 위한 페니실린이나 테트라사이클린과 같은 항생제는 충치균을 억제시키는데는 효과적이나, 장내균총에 영향을 주는 부작용이 크고, 클로로헥시딘은 충치형성을 저지하는 효과가 있으나 구강점막의 궤양이나 박리, 또는 치아에 실리콘을 부착시키는 등의 부작용이 있어 왔다. 한편 치주질환예방을 위하여서는 각종 유도체와 항플라스민제의 사용이 연구되고 있으나, 인체에 대한 안정성과 화합물 자체의 안성성이 떨어지는 단점이 있다.Antibiotics such as penicillin and tetracycline to remove caries in the oral cavity are effective in suppressing caries, but the side effects affecting the intestinal flora are high. Chlorohexidine is effective in preventing caries, but the ulcers in the oral mucosa There have been side effects such as peeling or adhesion of silicone to teeth. On the other hand, the use of various derivatives and antiplasmin agents for the prevention of periodontal disease has been studied, but there are disadvantages in the stability of the human body and the stability of the compound itself.

현재, 치약은 충치예방을 위해서 불소화합물을 가장 널리 사용해오고 있는 실정이다.At present, toothpaste has been the most widely used fluorine compounds to prevent tooth decay.

항균활성 물질중의 하나인 박테리오신은 일반 항생물질과 구분이 되는 항균물질로 그램 양성 젖산균에 의하여 생산되고 그 대부분이 저분자량의 단백질로 구성되어 있는데, 그 중 몇몇 종류는 충치균에 대한 우수한 억제작용을 갖고 있어서, 이를 이용한 새로운 치약 조성물을 제조하기에 이르렀다.Bacteriocin, one of the antimicrobial active substances, is an antimicrobial substance that is distinguished from ordinary antibiotics. It is produced by gram-positive lactic acid bacteria, and most of them are composed of low molecular weight proteins. It has come to produce a new toothpaste composition using the same.

3. 발명의 해결방법의 요지3. Summary of Solution to Invention

본 발명은 글리세린, 솔비톨, 카라기난, 사카린 나트륨, 실리카, 라우릴 황산나트륨, 및 정제수로 이루어진 치약 베이스(base)에, 박테리오신 생산 유산균의 건조된 배양조성물, 특히 락토코커스 스피시스 HY49의 건조된 배양조성물 0.01∼10.0중량%를 함유시킨 치약조성물, 및 상기 치약베이스에 정제된 박테리오신, 특히 상기 락토코커스 스피시스 HY49균주가 생산하는 박테리오신을 0.001∼1000ppm 함유시킨 치약조성물을 제공한다.The present invention provides a dried culture composition of bacteriocin-producing lactic acid bacteria, especially a dried culture composition of Lactococcus spis HY49, on a toothpaste base consisting of glycerin, sorbitol, carrageenan, sodium saccharin, silica, sodium lauryl sulfate, and purified water. Toothpaste composition containing -10.0% by weight, and a toothpaste composition containing 0.001 to 1000ppm of the bacteriocin purified in the toothpaste base, in particular the bacteriocin produced by the Lactococcus spis HY49 strain.

4. 발명의 중요한 용도4. Important uses of the invention

본 발명에 따른 치약조성물은 충치 억제 및 예방 효과가 뛰어난 치약으로 사용될 수 있다.Toothpaste composition according to the present invention can be used as a toothpaste excellent in inhibiting and preventing caries.

Description

충치 억제 및 예방용 치약조성물 및 그 제조방법Toothpaste composition for inhibiting and preventing tooth decay and manufacturing method thereof

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (5)

박테리오신 생산 유산균의 건조된 배양조성물을 0.01∼10.0중량% 함유하는 충치 억제 및 예방용 치약조성물.Toothpaste composition for caries suppression and prevention containing 0.01-10.0% by weight of the dried culture composition of bacteriocin-producing lactic acid bacteria. 정제된 박테리오신을 0.001∼1000ppm 함유하는 충치 억제 및 예방용 치약조성물.Toothpaste composition for inhibiting and preventing tooth decay, containing 0.001 to 1000 ppm of purified bacteriocin. 제1항에 있어서, 상기 건조된 배양조성물은 락토코커스 스피시스 HY49(Lactococcus sp. HY49; 동일출원인에 의한 특허출원 제94-22715호의 기탁번호 제KFCC-10842호의 균주)의 건조된 배양조성물인 것을 특징으로 하는 치약조성물.The method of claim 1, wherein the dried culture composition is a dried culture composition of Lactococcus spis HY49 (Lactococcus sp. HY49; Strain No. KFCC-10842 of Patent Application No. 94-22715 by the same applicant) Toothpaste composition characterized by. 제2항에 있어서, 상기 정제딘 박테리오신은 락토코커스 스피시스 HY49가 생산하는 박테리오신 물질인 것을 특징으로 하는 치약조성물.The dentifrice composition according to claim 2, wherein the purified din bacteriocin is a bacteriocin substance produced by Lactococcus spis HY49. 글리세린, 비결정 솔비톨, 카라기난, 사카린 나트륨, 실리카, 라우릴 황산 나트륨 및 정제수로 이루어진 치약베이스에, 박테리오신 생산 유산균의 건조된 배양조성물 0.01∼10.0중량% 또는 정제된 박테리오신 0.001∼1000ppm 을 함유시키는 것을 특징으로 하는 치약조성물의 제조방법.Toothpaste base consisting of glycerin, amorphous sorbitol, carrageenan, saccharin sodium, silica, sodium lauryl sulfate and purified water, 0.01 to 10.0% by weight of dried culture composition of bacteriocin-producing lactic acid bacteria or 0.001 to 1000 ppm of purified bacteriocin Method for producing a toothpaste composition. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019940038494A 1994-12-29 1994-12-29 Toothpaste composition for inhibiting and preventing tooth decay and manufacturing method thereof KR960020996A (en)

Priority Applications (1)

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KR1019940038494A KR960020996A (en) 1994-12-29 1994-12-29 Toothpaste composition for inhibiting and preventing tooth decay and manufacturing method thereof

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Application Number Priority Date Filing Date Title
KR1019940038494A KR960020996A (en) 1994-12-29 1994-12-29 Toothpaste composition for inhibiting and preventing tooth decay and manufacturing method thereof

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KR960020996A true KR960020996A (en) 1996-07-18

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