KR960000855A - L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물 - Google Patents

L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물 Download PDF

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KR960000855A
KR960000855A KR1019950014607A KR19950014607A KR960000855A KR 960000855 A KR960000855 A KR 960000855A KR 1019950014607 A KR1019950014607 A KR 1019950014607A KR 19950014607 A KR19950014607 A KR 19950014607A KR 960000855 A KR960000855 A KR 960000855A
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pharmaceutical composition
structural formula
composition according
treatment
carnitine
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KR1019950014607A
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클라우디오 카바자
파올로 카바자
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알도 파시
아방가르드 에스. 피. 에이.
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Publication of KR960000855A publication Critical patent/KR960000855A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/006—Antidandruff preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)

Abstract

본 발명은 다음 구조식(I)로 표시되는 신규 L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물에 관한 것으로서, 더욱 상세하게는 피부질환 치료를 위한 국소투여에 적합한 화장품 및 약제조성물의 유효성분으로서의 신규 L-카르니틴염의 용도에 관한 것이다.

Description

L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (8)

  1. 다음 구조식(I)로 표시되는 L-카르니틴 글리콜레이트
  2. 다음 구조식(I)로 표시되는 L-카르니틴 글리콜레이트를 유효성분으로 하고 약제학적으로 수용가능한 부형제로 이루어진 것을 특징으로 하는 피부질환 치료를 위한 국소투여에 적합한 약제조성물.
  3. 제2항에 있어서, 상기 약제조성물은 어린선 및 건선의 치료에 사용되는 것을 특징으로 하는 약제조성물.
  4. 제2항에 있어서, 상기 약제조성물은 각화결손에 의한 피부병 치료에 사용되는 것을 특징으로 하는 약제조성물.
  5. 제4항에 있어서, 상기 각화결손에 의한 피부병으로는 비듬, 여드름, 손바닥 각화증 또는 발바닥 각화증인 것을 특징으로 하는 약제조성물.
  6. 제2항에 있어서, 상기 약제조성물은 용액, 로션, 연고 또는 크림 형태임을 특징으로 하는 약제조성물.
  7. 제6항에 있어서, 상기 약제조성물은 상기 구조식(I)로 표시되는 L-카르티틴 글리콜레이트를 0.01~20중량%함유하는 것을 특징으로 하는 약제조성물.
  8. 다음 구조식(I)로 표시되는 L-카르니틴 글리콜레이트를 유효성분으로 하고 화장푸 제제학적으로 수용가능한 부형제로 이루어진 것을 특징으로 하는 화장품 조성물
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950014607A 1994-06-20 1995-06-02 L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물 KR960000855A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM940396A IT1272290B (it) 1994-06-20 1994-06-20 Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee
ITRM94A000396 1994-06-20

Publications (1)

Publication Number Publication Date
KR960000855A true KR960000855A (ko) 1996-01-25

Family

ID=11402602

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019950014607A KR960000855A (ko) 1994-06-20 1995-06-02 L-카르니틴염과 이를 함유한 피부질환 치료용 화장품 조성물 및 약제조성물
KR1019950015962A KR960000217A (ko) 1994-06-20 1995-06-16 L- 카르니틴염과 이를 함유한 조성물

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019950015962A KR960000217A (ko) 1994-06-20 1995-06-16 L- 카르니틴염과 이를 함유한 조성물

Country Status (13)

Country Link
US (1) US5591450A (ko)
EP (2) EP0688761A2 (ko)
JP (2) JPH0827081A (ko)
KR (2) KR960000855A (ko)
AT (1) ATE165338T1 (ko)
CA (2) CA2150407A1 (ko)
DE (1) DE69502147T2 (ko)
ES (1) ES2116651T3 (ko)
HK (1) HK1004918A1 (ko)
IT (1) IT1272290B (ko)
PH (1) PH31606A (ko)
TW (1) TW300881B (ko)
ZA (2) ZA955025B (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1272290B (it) * 1994-06-20 1997-06-16 Avantgarde Spa Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee
AUPN115095A0 (en) * 1995-02-15 1995-03-09 Butt, Henry Lawrence Analysis of and compositions and methods for the treatment of disease
IT1276253B1 (it) 1995-12-15 1997-10-27 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi
IT1289974B1 (it) * 1997-02-25 1998-10-19 Aldo Fassi Procedimento per la produzione di sali stabili e non igroscopici di l(-)carnitina e di alcanoli l(-)-carnitine
IT1291113B1 (it) * 1997-03-20 1998-12-29 Sigma Tau Ind Farmaceuti Composizione nutritiva terapeutica per soggetti affetti da diabete mellito
US6080788A (en) * 1997-03-27 2000-06-27 Sole; Michael J. Composition for improvement of cellular nutrition and mitochondrial energetics
US5863940A (en) 1997-12-01 1999-01-26 Sigma-Tau Healthscience S.P.A. Medicament and therapeutical method for treating idiopathic asthenozoospermia
US6090848A (en) * 1997-12-01 2000-07-18 Sigma-Tau Healthscience S.P.A. Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans
DK0951909T4 (da) 1998-03-19 2011-01-24 Sigma Tau Ind Farmaceuti Kombinationspræparat omfattende en L-carnitin eller en alkanoyl-L-carnitin, en glycosaminoglycan og/eller bestanddel deraf
KR20000050756A (ko) * 1999-01-14 2000-08-05 연규 핀 귀걸이의 제조방법과 그 제품의 구조
US6090849A (en) * 1999-03-23 2000-07-18 The Board Of Regents For Oklahoma State University Carnitine supplemented diet to prevent sudden death syndrome in breeder type poultry
ITRM20010364A1 (it) * 2001-06-25 2002-12-27 Biosalts Srl Ascorbil derivati di carnitine e composizioni cosmetiche contenenti tali derivati.
JP2006522807A (ja) * 2003-03-28 2006-10-05 ロンザ インコーポレイテッド 局所的ｌ−カルニチン組成物
JP4539096B2 (ja) * 2004-01-16 2010-09-08 日油株式会社 油性成分被覆ｌ−カルニチン塩粉末およびその用途
CN1322860C (zh) * 2004-08-31 2007-06-27 北京正大绿洲医药科技有限公司 左旋肉碱滴丸及其制备方法
US7572832B2 (en) * 2007-03-19 2009-08-11 Biolink Life Sciences, Inc. Non-hygroscopic L-carnitine salts
KR101633846B1 (ko) 2013-11-25 2016-06-27 주식회사 엘지화학 도전성 패턴 형성용 조성물 및 도전성 패턴을 갖는 수지 구조체
RU2704251C2 (ru) * 2015-03-27 2019-10-25 Цзянсу Хэнжуй Медсин Ко., Лтд. П-толуолсульфонат для ингибитора мек-киназы и его кристаллическая форма, и способ его получения
CN107216339B (zh) * 2016-03-22 2021-05-04 中国科学院上海药物研究所 一种dppiv抑制剂马来酸盐的多晶型及其制备方法
CN107216340B (zh) * 2016-03-22 2021-05-04 中国科学院上海药物研究所 一种dppiv抑制剂的盐型及其制备方法
SE542106C2 (en) * 2016-08-26 2020-02-25 Atif M Dabdoub Dietary macro/micronutritional supplement for patients undergoing kidney dialysis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0150688B1 (en) 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
FR2627385B3 (fr) * 1988-02-23 1991-08-23 Serobiologiques Lab Sa Composition notamment utile comme matiere de base pour la preparation de compositions pharmaceutiques, notamment dermatologiques et/ou cosmetiques
US4968719A (en) * 1989-04-03 1990-11-06 Sigma Tau, Industrie Farmaceutiche Riunite Spa Method for treating vascular disease
US5137910A (en) * 1989-05-05 1992-08-11 C.D. Searle & Co. Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders
IT1263013B (it) * 1992-10-20 1996-07-23 Avantgarde Spa Esteri della l-carnitina e di alcanoil l-carnitine con l'acido glicolico o suoi esteri e composizioni farmaceutiche contenenti tali per il trattamento di affezioni cutanee.
IT1261984B (it) * 1993-06-22 1996-06-11 Avantgarde Spa Uso di esteri della l-carnitina o di acil l- carnitine con idrossiacidi per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
IT1272290B (it) * 1994-06-20 1997-06-16 Avantgarde Spa Sale della l-carnitina e composizioni farmaceutiche che lo contengono per il trattamento di affezioni cutanee

Also Published As

Publication number Publication date
EP0697397B1 (en) 1998-04-22
ITRM940396A1 (it) 1995-12-20
DE69502147D1 (de) 1998-05-28
ZA955024B (en) 1996-02-08
CA2152005A1 (en) 1995-12-21
KR960000217A (ko) 1996-01-25
ES2116651T3 (es) 1998-07-16
EP0688761A3 (ko) 1996-01-17
US5591450A (en) 1997-01-07
EP0688761A2 (en) 1995-12-27
IT1272290B (it) 1997-06-16
ATE165338T1 (de) 1998-05-15
HK1004918A1 (en) 1998-12-11
ZA955025B (en) 1996-02-08
JPH0826984A (ja) 1996-01-30
PH31606A (en) 1998-11-03
DE69502147T2 (de) 1998-08-13
EP0697397A1 (en) 1996-02-21
JPH0827081A (ja) 1996-01-30
ITRM940396A0 (it) 1994-06-20
TW300881B (ko) 1997-03-21
CA2150407A1 (en) 1995-12-21

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