KR950700291A - 5-ht1 작용물질로서의 인돌 유도체(indole derivatives as 5-ht1 agonists) - Google Patents

5-ht1 작용물질로서의 인돌 유도체(indole derivatives as 5-ht1 agonists)

Info

Publication number: KR950700291A
Authority: KR; South Korea
Prior art keywords: pct; agonists; compounds; indole derivatives; sec
Prior art date: 1992-03-05

Application number

KR1019940703076A

Other languages

English (en)

Other versions

KR0179073B1 (ko

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-03-05

Filing date

1994-09-03

Publication date

1995-01-16

1993-03-03 Application filed filed Critical

1995-01-16 Publication of KR950700291A publication Critical patent/KR950700291A/ko

1999-03-20 Application granted granted Critical

1999-03-20 Publication of KR0179073B1 publication Critical patent/KR0179073B1/ko

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Addiction (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

KR1019940703076A 1992-03-05 1993-03-03 5-ht1 작용물질로서의 인돌 유도체 KR0179073B1 (ko)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US84664092A	1992-03-05	1992-03-05
US846,640		1992-03-05
PCT/US1993/001667 WO1993018032A1 (en)	1992-03-05	1993-03-03	Indole derivatives as 5-ht1 agonists

Publications (2)

Publication Number	Publication Date
KR950700291A true KR950700291A (ko)	1995-01-16
KR0179073B1 KR0179073B1 (ko)	1999-03-20

Family

ID=25298499

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019940703076A KR0179073B1 (ko)	1992-03-05	1993-03-03	5-ht1 작용물질로서의 인돌 유도체

Country Status (30)

Country	Link
US (2)	US5594014A (ko)
EP (1)	EP0629199B1 (ko)
JP (1)	JPH07121943B2 (ko)
KR (1)	KR0179073B1 (ko)
CN (4)	CN1032309C (ko)
AT (1)	ATE218566T1 (ko)
AU (1)	AU666716B2 (ko)
BR (1)	BR9306012A (ko)
CA (1)	CA2117643C (ko)
CZ (1)	CZ282652B6 (ko)
DE (1)	DE69331988T2 (ko)
DK (1)	DK0629199T3 (ko)
EG (1)	EG20416A (ko)
ES (1)	ES2176199T3 (ko)
FI (1)	FI930968A (ko)
HU (1)	HU219489B (ko)
IL (1)	IL104941A (ko)
MX (1)	MX9301197A (ko)
MY (1)	MY109298A (ko)
NO (1)	NO302617B1 (ko)
NZ (1)	NZ249755A (ko)
PL (1)	PL172388B1 (ko)
PT (1)	PT629199E (ko)
RU (1)	RU2124012C1 (ko)
SK (1)	SK281938B6 (ko)
TW (1)	TW288010B (ko)
UA (1)	UA39866C2 (ko)
WO (1)	WO1993018032A1 (ko)
YU (1)	YU14893A (ko)
ZA (1)	ZA931539B (ko)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5559246A (en) *	1990-10-15	1996-09-24	Pfizer Inc.	Indole derivatives
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
US5559129A (en) *	1990-10-15	1996-09-24	Pfizer Inc	Indole derivatives
US5607951A (en) *	1990-10-15	1997-03-04	Pfizer Inc	Indole derivatives
US5578612A (en) *	1990-10-15	1996-11-26	Pfizer Inc.	Indole derivatives
UA27467C2 (uk)	1992-04-07	2000-09-15	Пфайзер Інк.	ПОХІДНІ ІНДОЛУ ЯК 5-НТ<sub>1</sub> АГОНІСТИ ТА ПРОМІЖНІ СПОЛУКИ
US6380233B1 (en)	1992-04-07	2002-04-30	Pfizer Inc	Indole derivatives as 5-HT1 agonists
US5849739A (en) *	1993-08-31	1998-12-15	Pfizer Inc.	5-arylindole derivatives
GB9417310D0 (en)	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
GB9420503D0 (en) *	1994-10-11	1994-11-23	Pfizer Ltd	Therapeutic agents
GB9420529D0 (en)	1994-10-12	1994-11-30	Pfizer Ltd	Indoles
US6288091B1 (en)	1995-12-29	2001-09-11	Boehringer Ingelheim Ltd.	Antiherpes virus compounds and methods for their preparation and use
TR199801244T2 (xx)	1995-12-29	1998-12-21	Boehringer Ingelheim Pharmaceuticals, Inc.	Herpese kar�� zellikler ta��yan fenil tiyazol t�revleri.
US5994352A (en) *	1998-11-13	1999-11-30	Pfizer Inc.	5-arylindole derivatives
CZ20031257A3 (cs)	2000-11-27	2004-04-14	Pfizer Products Inc.	Selektivní agonisty receptoru EP4 při léčení osteoporosy
US6831094B2 (en) *	2001-04-20	2004-12-14	Wyeth	Heterocyclylalkoxy-,-alkylthio-and -alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands
ITRM20020255A1 (it) *	2002-05-09	2003-11-10	Polifarma Spa	Tautomero enolico dell'acido 3-indolilpiruvico, suoi sali e usi terapeutici.
ES2199086B1 (es) *	2002-07-31	2005-06-01	Cepa Schwarz Pharma Sl	Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
EP2919788A4 (en)	2012-11-14	2016-05-25	Univ Johns Hopkins	METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA
IL295374A (en) *	2020-02-04	2022-10-01	Mindset Pharma Inc	3-pyrrolidine indole derivatives as serotonergic psychedelics for the treatment of central nervous system disorders

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
BE889931A (fr) *	1980-08-12	1982-02-11	Glaxo Group Ltd	Derives indoliques, leur preparation et leurs applications en tant que medicaments
GB8600397D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
GB8719167D0 (en) *	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
GB8724912D0 (en) *	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
IL96891A0 (en) *	1990-01-17	1992-03-29	Merck Sharp & Dohme	Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr) *	1990-05-15	1991-11-16	Jacques Chauveau	Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
MC2210A1 (fr) *	1990-06-07	1992-11-26	Wellcome Found	Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
DE9190141U1 (de) *	1990-10-15	1993-07-15	Pfizer Inc., New York, N.Y.	Indolderivate
US5208248A (en) *	1991-01-11	1993-05-04	Merck Sharpe & Dohme, Ltd.	Indazole-substituted five-membered heteroaromatic compounds
CZ283018B6 (cs) *	1991-02-01	1997-12-17	Merck Sharp And Dohme Limited	Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
TW263508B (ko) *	1991-02-12	1995-11-21	Pfizer

1993
- 1993-02-09 TW TW082100871A patent/TW288010B/zh active
- 1993-03-03 EP EP93906214A patent/EP0629199B1/en not_active Expired - Lifetime
- 1993-03-03 AT AT93906214T patent/ATE218566T1/de not_active IP Right Cessation
- 1993-03-03 MX MX9301197A patent/MX9301197A/es unknown
- 1993-03-03 BR BR9306012A patent/BR9306012A/pt not_active Application Discontinuation
- 1993-03-03 JP JP5515745A patent/JPH07121943B2/ja not_active Expired - Fee Related
- 1993-03-03 DE DE69331988T patent/DE69331988T2/de not_active Expired - Fee Related
- 1993-03-03 CZ CZ942125A patent/CZ282652B6/cs not_active IP Right Cessation
- 1993-03-03 US US08/284,662 patent/US5594014A/en not_active Expired - Fee Related
- 1993-03-03 RU RU94040914/04A patent/RU2124012C1/ru not_active IP Right Cessation
- 1993-03-03 WO PCT/US1993/001667 patent/WO1993018032A1/en active IP Right Grant
- 1993-03-03 PT PT93906214T patent/PT629199E/pt unknown
- 1993-03-03 AU AU37330/93A patent/AU666716B2/en not_active Ceased
- 1993-03-03 EG EG12893A patent/EG20416A/xx active
- 1993-03-03 ES ES93906214T patent/ES2176199T3/es not_active Expired - Lifetime
- 1993-03-03 CA CA002117643A patent/CA2117643C/en not_active Expired - Fee Related
- 1993-03-03 KR KR1019940703076A patent/KR0179073B1/ko not_active IP Right Cessation
- 1993-03-03 PL PL93305051A patent/PL172388B1/pl not_active IP Right Cessation
- 1993-03-03 UA UA94095775A patent/UA39866C2/uk unknown
- 1993-03-03 SK SK1052-94A patent/SK281938B6/sk unknown
- 1993-03-03 DK DK93906214T patent/DK0629199T3/da active
- 1993-03-04 CN CN93104036A patent/CN1032309C/zh not_active Expired - Fee Related
- 1993-03-04 HU HU9300593A patent/HU219489B/hu not_active IP Right Cessation
- 1993-03-04 YU YU14893A patent/YU14893A/sh unknown
- 1993-03-04 ZA ZA931539A patent/ZA931539B/xx unknown
- 1993-03-04 MY MYPI93000388A patent/MY109298A/en unknown
- 1993-03-04 FI FI930968A patent/FI930968A/fi not_active Application Discontinuation
- 1993-03-04 IL IL104941A patent/IL104941A/en not_active IP Right Cessation
- 1993-05-03 NZ NZ249755A patent/NZ249755A/en unknown
1994
- 1994-09-02 NO NO943261A patent/NO302617B1/no not_active IP Right Cessation
1995
- 1995-11-17 CN CN95118794A patent/CN1082815C/zh not_active Expired - Fee Related
- 1995-11-17 CN CN95118795A patent/CN1044909C/zh not_active Expired - Fee Related
- 1995-11-17 CN CN95118796A patent/CN1044910C/zh not_active Expired - Fee Related
1996
- 1996-12-31 US US08/777,835 patent/US5717102A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CZ212594A3 (en)	1995-06-14
CA2117643A1 (en)	1993-09-16
EP0629199A1 (en)	1994-12-21
CN1082044A (zh)	1994-02-16
FI930968A (fi)	1993-09-06
WO1993018032A1 (en)	1993-09-16
NO302617B1 (no)	1998-03-30
RU94040914A (ru)	1996-08-10
CN1136432A (zh)	1996-11-27
PT629199E (pt)	2002-09-30
DE69331988D1 (de)	2002-07-11
AU3733093A (en)	1993-10-05
CA2117643C (en)	2000-03-14
JPH07500353A (ja)	1995-01-12
NZ249755A (en)	1996-08-27
DE69331988T2 (de)	2002-09-19
RU2124012C1 (ru)	1998-12-27
UA39866C2 (uk)	2001-07-16
YU14893A (sh)	1996-05-20
NO943261D0 (no)	1994-09-02
CN1044909C (zh)	1999-09-01
US5717102A (en)	1998-02-10
ZA931539B (en)	1994-09-05
SK105294A3 (en)	1995-05-10
JPH07121943B2 (ja)	1995-12-25
BR9306012A (pt)	1997-11-18
KR0179073B1 (ko)	1999-03-20
HU219489B (hu)	2001-04-28
ATE218566T1 (de)	2002-06-15
PL172388B1 (pl)	1997-09-30
IL104941A (en)	1998-06-15
TW288010B (ko)	1996-10-11
HU9300593D0 (en)	1993-05-28
EG20416A (en)	1999-02-28
CN1136565A (zh)	1996-11-27
ES2176199T3 (es)	2002-12-01
CN1082815C (zh)	2002-04-17
CN1136566A (zh)	1996-11-27
MY109298A (en)	1996-12-31
MX9301197A (es)	1993-09-01
US5594014A (en)	1997-01-14
CZ282652B6 (cs)	1997-08-13
DK0629199T3 (da)	2002-07-15
NO943261L (no)	1994-09-02
EP0629199B1 (en)	2002-06-05
CN1032309C (zh)	1996-07-17
HUT64061A (en)	1993-11-29
IL104941A0 (en)	1993-07-08
AU666716B2 (en)	1996-02-22
SK281938B6 (sk)	2001-09-11
FI930968A0 (fi)	1993-03-04
CN1044910C (zh)	1999-09-01

Legal Events

Date	Code	Title	Description
1994-09-03	A201	Request for examination
1997-08-26	E902	Notification of reason for refusal
1997-11-26	AMND	Amendment
1998-02-17	E801	Decision on dismissal of amendment
1998-06-15	J121	Written withdrawal of request for trial
1998-07-22	E601	Decision to refuse application
1998-08-28	J201	Request for trial against refusal decision
1998-09-30	B701	Decision to grant
1998-11-26	GRNT	Written decision to grant
2002-10-28	FPAY	Annual fee payment	Payment date: 20021029 Year of fee payment: 5
2003-11-27	LAPS	Lapse due to unpaid annual fee

Publication	Publication Date	Title
EG21209A (en)	2001-01-31	Indole derivatives
KR950700291A (ko)	1995-01-16	5-ht1 작용물질로서의 인돌 유도체(indole derivatives as 5-ht1 agonists)
MX9700693A (es)	1997-04-30	Derivados del 4-indol.
HU9301048D0 (en)	1993-06-28	Acyl-amino-indole derivatives
ES2070772A1 (es)	1995-06-01	Derivados de acilaminoindol