KR950016742A - 폐경후 여성의 씨엔에스 질환을 억제하는 방법 - Google Patents
폐경후 여성의 씨엔에스 질환을 억제하는 방법 Download PDFInfo
- Publication number
- KR950016742A KR950016742A KR1019940034933A KR19940034933A KR950016742A KR 950016742 A KR950016742 A KR 950016742A KR 1019940034933 A KR1019940034933 A KR 1019940034933A KR 19940034933 A KR19940034933 A KR 19940034933A KR 950016742 A KR950016742 A KR 950016742A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- postmenopausal women
- cns disease
- chem
- formula
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
본 발명은 효과량의 하기 일반식(Ⅰ)의 화합물, 또는 그의 약학적으로 허용가능한 염 또는 용매화물을 하나이상의 CNS 질환의 억제를 필요로 하는 폐경후 여성에게 투여함을 포함하는, 상기 질환의 억제방법에 관한 것이다.
상기식에서,
R1및 R3는 독립적으로 수소,(여기에서, Ar은 임의로 치환된 페닐이다)이고; R2는 피롤리디노, 헥사메틸렌이미노 및 피페리디노로 이루어진 그룹중에서 선택된다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- 폐경후 여성의 하나이상의 CNS질환을 억제하는데 사용하기 위한 하기 일반식( I )의 화합물, 또는 그의 약학적으로 허용가능한 염 또는 용매화물:상기식에서,R1및 R3는 독립적으로 수소,(여기에서, Ar은 임의로 치환된 페닐이다)이고; R2는 피롤리디노, 헥사메틸렌이미노 및 피페리디노로 이루어진 그룹중에서 선택된다.
- 제1항에 있어서, 상기 화합물이 그의 염산 염인 화합물.
- 제1항에 있어서, 예방목적으로 투여하는 화합물.
- 제1항에 있어서, 상기 화합물이또는 그의 염산 염인 화합물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/171,388 US6417198B1 (en) | 1993-12-21 | 1993-12-21 | Methods of inhibiting CNS problems in post-menopausal women |
US08/171,388 | 1993-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR950016742A true KR950016742A (ko) | 1995-07-20 |
Family
ID=22623561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019940034933A KR950016742A (ko) | 1993-12-21 | 1994-12-19 | 폐경후 여성의 씨엔에스 질환을 억제하는 방법 |
Country Status (22)
Country | Link |
---|---|
US (2) | US6417198B1 (ko) |
EP (1) | EP0659413B1 (ko) |
JP (1) | JPH07196502A (ko) |
KR (1) | KR950016742A (ko) |
CN (1) | CN1107332A (ko) |
AT (1) | ATE206920T1 (ko) |
AU (1) | AU692491B2 (ko) |
CA (1) | CA2138459A1 (ko) |
CZ (1) | CZ288503B6 (ko) |
DE (1) | DE69428665T2 (ko) |
DK (1) | DK0659413T3 (ko) |
ES (1) | ES2162845T3 (ko) |
HU (1) | HUT71329A (ko) |
IL (1) | IL112045A (ko) |
NO (1) | NO944929L (ko) |
NZ (1) | NZ270181A (ko) |
PH (1) | PH31328A (ko) |
PT (1) | PT659413E (ko) |
RU (1) | RU2138261C1 (ko) |
SI (1) | SI0659413T1 (ko) |
UA (1) | UA27004C2 (ko) |
ZA (1) | ZA9410082B (ko) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030075998A (ko) * | 2002-03-22 | 2003-09-26 | 임은규 | 목욕용 생약제 조성물 |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5492927A (en) * | 1993-12-21 | 1996-02-20 | Eli Lilly And Company | Non-peptide tachykinin receptor antagonists to treat allergy |
US5512296A (en) * | 1994-08-22 | 1996-04-30 | Eli Lilly And Company | Methods for inhibiting neuronal damage |
US6562862B1 (en) * | 1994-10-20 | 2003-05-13 | Eli Lilly And Company | Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y |
IL115613A0 (en) * | 1994-10-20 | 1996-01-19 | Lilly Co Eli | Bicyclic neuropeptide y receptor antagonists |
IL120266A (en) | 1996-02-28 | 2005-05-17 | Pfizer | Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions |
TW442286B (en) * | 1996-02-28 | 2001-06-23 | Pfizer | New therapeutic uses of estrogen agonists |
ZA982877B (en) * | 1997-04-09 | 1999-10-04 | Lilly Co Eli | Treatment of central nervous system disorders with selective estrogen receptor modulators. |
US6117911A (en) * | 1997-04-11 | 2000-09-12 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
US5990129A (en) * | 1997-09-23 | 1999-11-23 | Eli Lilly And Company | Methods for regulating trkA expression |
US6054446A (en) | 1997-12-24 | 2000-04-25 | Sri International | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use |
EP1175433B1 (en) | 1999-05-04 | 2005-08-03 | Strakan International Limited | Androgen glycosides and androgenic activity thereof |
US20060275806A1 (en) * | 2005-05-11 | 2006-12-07 | Schwartz David C | Whole genome methylation profiles via single molecule analysis |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE637389A (ko) * | 1962-09-13 | |||
US4133814A (en) | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
US4380635A (en) | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
US4418068A (en) | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
US4729999A (en) | 1984-10-12 | 1988-03-08 | Bcm Technologies | Antiestrogen therapy for symptoms of estrogen deficiency |
US5075321A (en) * | 1987-03-24 | 1991-12-24 | University Of Pennsylvania | Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes |
US5395842A (en) | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
TW366342B (en) * | 1992-07-28 | 1999-08-11 | Lilly Co Eli | The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss |
TW383306B (en) | 1992-12-22 | 2000-03-01 | Lilly Co Eli | New use of 2-phenyl-3-aroylbenzothiophenes in lowering serum cholesterol |
US5482949A (en) | 1993-03-19 | 1996-01-09 | Eli Lilly And Company | Sulfonate derivatives of 3-aroylbenzo[b]thiophenes |
US5445941A (en) | 1993-06-21 | 1995-08-29 | Eli Lilly And Company | Method for screening anti-osteoporosis agents |
DE4320896A1 (de) | 1993-06-24 | 1995-01-05 | Denecke Rainer Dr Med Vet | Präparat zur Therapie und Prophylaxe von Demenz-Erkrankungen |
CZ285522B6 (cs) | 1993-06-24 | 1999-08-11 | Eli Lilly And Company | Farmaceutický prostředek pro snížení koncentrace glukosy v krvi |
TW303299B (ko) | 1993-07-22 | 1997-04-21 | Lilly Co Eli | |
US5441947A (en) | 1993-08-25 | 1995-08-15 | Eli Lilly And Company | Methods of inhibiting vascular restenosis |
US5468773A (en) | 1993-08-25 | 1995-11-21 | Eli Lilly And Company | Methods for inhibiting bone loss and cartilage degradation using wortmannin and its analogs |
US5391557A (en) * | 1993-10-15 | 1995-02-21 | Eli Lilly And Company | Methods for the treatment of peri-menopausal syndrome |
US5462950A (en) | 1993-12-21 | 1995-10-31 | Eli Lilly And Company | Methods of treating menstrual symptoms and compositions therefore |
US5492927A (en) * | 1993-12-21 | 1996-02-20 | Eli Lilly And Company | Non-peptide tachykinin receptor antagonists to treat allergy |
US5552415A (en) | 1993-12-21 | 1996-09-03 | Eli Lilly And Company | Method of inhibiting Alzheimer's Disease |
US5439931A (en) | 1993-12-21 | 1995-08-08 | Eli Lilly And Company | Method for increasing libido in post-menopausal women |
US5534526A (en) | 1993-12-21 | 1996-07-09 | Eli Lilly And Company | Methods for inhibiting vasomotor symptoms and attending psychological disturbances surrounding post-menopausal syndrome |
US5578613A (en) | 1993-12-21 | 1996-11-26 | Eli Lilly And Company | Methods for inhibiting weight gain or inducing weight loss |
US5389670A (en) | 1993-12-21 | 1995-02-14 | Eli Lilly Company | Methods of inhibiting the symptoms of premenstrual syndrome/late luteal phase dysphoric disorder |
US5434166A (en) | 1994-08-22 | 1995-07-18 | Eli Lilly And Company | Methods of inhibiting demyelinating and desmyelinating diseases |
US5512296A (en) | 1994-08-22 | 1996-04-30 | Eli Lilly And Company | Methods for inhibiting neuronal damage |
JP4111352B2 (ja) | 1996-05-21 | 2008-07-02 | 新日鐵住金ステンレス株式会社 | ステンレス鋼の高清浄化精錬法 |
-
1993
- 1993-12-21 US US08/171,388 patent/US6417198B1/en not_active Expired - Fee Related
-
1994
- 1994-12-19 IL IL11204594A patent/IL112045A/en not_active IP Right Cessation
- 1994-12-19 ZA ZA9410082A patent/ZA9410082B/xx unknown
- 1994-12-19 ES ES94309470T patent/ES2162845T3/es not_active Expired - Lifetime
- 1994-12-19 EP EP94309470A patent/EP0659413B1/en not_active Expired - Lifetime
- 1994-12-19 KR KR1019940034933A patent/KR950016742A/ko not_active Application Discontinuation
- 1994-12-19 PH PH49591A patent/PH31328A/en unknown
- 1994-12-19 CN CN94119267A patent/CN1107332A/zh active Pending
- 1994-12-19 NZ NZ270181A patent/NZ270181A/xx unknown
- 1994-12-19 PT PT94309470T patent/PT659413E/pt unknown
- 1994-12-19 AT AT94309470T patent/ATE206920T1/de not_active IP Right Cessation
- 1994-12-19 CZ CZ19943225A patent/CZ288503B6/cs not_active IP Right Cessation
- 1994-12-19 HU HU9403679A patent/HUT71329A/hu unknown
- 1994-12-19 AU AU81562/94A patent/AU692491B2/en not_active Ceased
- 1994-12-19 NO NO944929A patent/NO944929L/no not_active Application Discontinuation
- 1994-12-19 RU RU94045277A patent/RU2138261C1/ru active
- 1994-12-19 SI SI9430401T patent/SI0659413T1/xx unknown
- 1994-12-19 JP JP6314558A patent/JPH07196502A/ja active Pending
- 1994-12-19 UA UA94129190A patent/UA27004C2/uk unknown
- 1994-12-19 DK DK94309470T patent/DK0659413T3/da active
- 1994-12-19 CA CA002138459A patent/CA2138459A1/en not_active Abandoned
- 1994-12-19 DE DE69428665T patent/DE69428665T2/de not_active Expired - Fee Related
-
1995
- 1995-04-28 US US08/432,438 patent/US5663184A/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030075998A (ko) * | 2002-03-22 | 2003-09-26 | 임은규 | 목욕용 생약제 조성물 |
Also Published As
Publication number | Publication date |
---|---|
ATE206920T1 (de) | 2001-11-15 |
CA2138459A1 (en) | 1995-06-22 |
CZ322594A3 (en) | 1995-08-16 |
NO944929L (no) | 1995-06-22 |
DE69428665T2 (de) | 2002-07-11 |
ES2162845T3 (es) | 2002-01-16 |
EP0659413A3 (en) | 1995-10-11 |
IL112045A (en) | 1999-03-12 |
US5663184A (en) | 1997-09-02 |
IL112045A0 (en) | 1995-03-15 |
ZA9410082B (en) | 1996-06-19 |
US6417198B1 (en) | 2002-07-09 |
DK0659413T3 (da) | 2001-12-03 |
SI0659413T1 (en) | 2002-04-30 |
UA27004C2 (uk) | 2000-02-28 |
DE69428665D1 (de) | 2001-11-22 |
HU9403679D0 (en) | 1995-02-28 |
EP0659413B1 (en) | 2001-10-17 |
AU8156294A (en) | 1995-06-29 |
RU2138261C1 (ru) | 1999-09-27 |
NO944929D0 (no) | 1994-12-19 |
JPH07196502A (ja) | 1995-08-01 |
NZ270181A (en) | 1997-08-22 |
AU692491B2 (en) | 1998-06-11 |
CN1107332A (zh) | 1995-08-30 |
RU94045277A (ru) | 1996-11-10 |
PH31328A (en) | 1998-07-06 |
HUT71329A (en) | 1995-11-28 |
PT659413E (pt) | 2002-02-28 |
EP0659413A2 (en) | 1995-06-28 |
CZ288503B6 (cs) | 2001-07-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR970706818A (ko) | 뉴로펩티드 y와 관련된 상태의 억제 방법(methods of inhibiting conditions associated with neuropeptide) | |
KR950016738A (ko) | 알쯔하이머 질병의 억제 방법 | |
KR950016744A (ko) | 트롬빈을 저해하는 방법 | |
KR950016745A (ko) | 생리증상의 치료방법 및 이를 위한 조성물 | |
KR950016746A (ko) | 비-펩티드 타키키닌 수용체 길항물질 | |
KR950010893A (ko) | 자궁내막증 억제 방법 | |
KR950016732A (ko) | 피부 및 질의 위축 억제방법 | |
KR950016742A (ko) | 폐경후 여성의 씨엔에스 질환을 억제하는 방법 | |
KR950010892A (ko) | 자궁 섬유증 억제 방법 | |
KR950016725A (ko) | 폐 고혈압성 질병을 억제하는 방법 | |
KR950016724A (ko) | 폐경기 후 여성의 리비도를 증가시키는 방법 | |
KR950016731A (ko) | 지루 및 좌창의 억제 방법 | |
KR950010889A (ko) | 혈관형성 및 혈관형성성 질병을 억제하는 방법 | |
KR950016723A (ko) | 자가면역 질병의 억제 방법 | |
KR950016726A (ko) | 기능부전성 자궁 출혈을 억제하는 방법 | |
KR950010891A (ko) | 내성 종양을 치료하는 방법 | |
KR950016729A (ko) | 유방 질환의 억제 방법 | |
KR950016734A (ko) | 성적 조숙증의 억제방법 | |
KR970705384A (ko) | 골 보철 파손의 억제 방법(methods for inhibiting bone prosthesis degeneration) | |
KR950016728A (ko) | 여성에서 다모증 및 탈모증을 억제하는 방법 | |
KR970706819A (ko) | 브라디키닌 관련 증상 억제 방법(Method of Inhibiting Conditions Associated with Bradykinin) | |
KR950016739A (ko) | 강박관념 질환 및 소모성 질환을 억제하는 방법 | |
KR970705387A (ko) | 자궁내막암의 억제 방법(methods of inhibiting endometrial cancer) | |
KR950016736A (ko) | 남성 불임증의 억제 방법 | |
KR970705385A (ko) | 뼈 치료법 및 골절 치유법(methods for bone healing and fracture repair) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application |