KR910003113A - 항생물질 플러스박신 - Google Patents

항생물질 플러스박신 Download PDF

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Publication number
KR910003113A
KR910003113A KR1019900011264A KR900011264A KR910003113A KR 910003113 A KR910003113 A KR 910003113A KR 1019900011264 A KR1019900011264 A KR 1019900011264A KR 900011264 A KR900011264 A KR 900011264A KR 910003113 A KR910003113 A KR 910003113A
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KR
South Korea
Prior art keywords
compound
integer
hypro
pro
medium
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KR1019900011264A
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English (en)
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KR960007618B1 (ko
Inventor
다다시 요시다
준이찌 쇼지
데루오 핫또리
고이찌 마쓰모또
Original Assignee
요시또시 가즈오
시오노기세이야꾸 가부시끼가이샤
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Application filed by 요시또시 가즈오, 시오노기세이야꾸 가부시끼가이샤 filed Critical 요시또시 가즈오
Publication of KR910003113A publication Critical patent/KR910003113A/ko
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Publication of KR960007618B1 publication Critical patent/KR960007618B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

내용 없음.

Description

항생물질 플러스박신
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 플러스박신 A2및 B2염산염의 IR 스펙트럼을 나타낸다.

Claims (4)

  1. 하기 일반식의 화합물 또는 그의 염:
    (식중, X는 L-HyPro 또는 L-Pro이고, R은 -CH3또는 -CH(CH3)2이고, 및 n은 9~12의 정수이다).
  2. 제1항에 있어서, n이 정수 9,10 또는 12인 화합물 또는 그의 염.
  3. (a)하기 일반식의 화합물을 생성하여 수도모나스속에 속하는 미생물을 배지에서 배양하고 (b)배지로 부터 화합물을 회수함을 특징으로 하는 하기 일반식의 화합물 또는 그의염의 제조방법:
    (식중, X는 L-HyPro 또는 L-Pro이고, R은 -CH3또는 -CH(CH3)2이고, 및 n은 9~12의 정수이다).
  4. 하기 일반식의 화합물을 생성하는 수도모나스 종(Pseudomonas sp.) PB-6250의 생물학적으로 순수한 배양물.
    (식중, X는 L-HyPro 또는 L-Pro이고, R은 -CH3또는 -CH(CH3)2이고, 및 n은 9~12의 정수이다).
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900011264A 1989-07-24 1990-07-24 항생물질 플러스박신 KR960007618B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP192317/1989 1989-07-24
JP19231789 1989-07-24
JP21823889 1989-08-24
JP218238/1989 1989-08-24
JP262634/1989 1989-10-06
JP1262634A JP2863934B2 (ja) 1989-07-24 1989-10-06 抗生物質プラスバシン

Publications (2)

Publication Number Publication Date
KR910003113A true KR910003113A (ko) 1991-02-26
KR960007618B1 KR960007618B1 (ko) 1996-06-07

Family

ID=27326594

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900011264A KR960007618B1 (ko) 1989-07-24 1990-07-24 항생물질 플러스박신

Country Status (10)

Country Link
US (1) US5171836A (ko)
EP (1) EP0413967B1 (ko)
JP (1) JP2863934B2 (ko)
KR (1) KR960007618B1 (ko)
AT (1) ATE113608T1 (ko)
AU (1) AU631666B2 (ko)
CA (1) CA2019463C (ko)
DE (1) DE69013809T2 (ko)
DK (1) DK0413967T3 (ko)
ES (1) ES2066054T3 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU669187B2 (en) * 1992-08-25 1996-05-30 Shionogi & Co., Ltd. Antibiotic stalobacins
US6103231A (en) * 1992-08-25 2000-08-15 Shionogi & Co., Ltd. Antibiotic stalobacins
WO2002066499A1 (fr) * 2001-02-19 2002-08-29 Takara Bio Inc. Peptide cyclique

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208403A (en) * 1978-10-16 1980-06-17 Eli Lilly And Company A-21978 Antibiotics and process for their production
US4370266A (en) * 1980-04-07 1983-01-25 Sankyo Company, Limited Mycoplanecin derivatives and their preparation
US4409210A (en) * 1982-01-15 1983-10-11 Bristol-Myers Company Antibiotic compound
US4533631A (en) * 1982-01-15 1985-08-06 Bristol-Myers Company Fermentation process for preparation of antibiotic Bu-2517
US5028590A (en) * 1988-04-11 1991-07-02 Eli Lilly And Company Derivatives of A54145 cyclic peptides
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
US5039789A (en) * 1988-04-11 1991-08-13 Eli Lilly And Company A54145 cyclic peptides

Also Published As

Publication number Publication date
ES2066054T3 (es) 1995-03-01
DK0413967T3 (da) 1994-11-21
AU631666B2 (en) 1992-12-03
DE69013809D1 (de) 1994-12-08
EP0413967A1 (en) 1991-02-27
DE69013809T2 (de) 1995-03-23
CA2019463A1 (en) 1991-01-24
JPH03188098A (ja) 1991-08-16
AU5972690A (en) 1991-01-24
US5171836A (en) 1992-12-15
ATE113608T1 (de) 1994-11-15
EP0413967B1 (en) 1994-11-02
JP2863934B2 (ja) 1999-03-03
CA2019463C (en) 1999-03-16
KR960007618B1 (ko) 1996-06-07

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