KR910002468A - 인간 인터로이킨-6 수용체에 대한 항체 - Google Patents

인간 인터로이킨-6 수용체에 대한 항체

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Publication number
KR910002468A
KR910002468A KR1019890011023A KR890011023A KR910002468A KR 910002468 A KR910002468 A KR 910002468A KR 1019890011023 A KR1019890011023 A KR 1019890011023A KR 890011023 A KR890011023 A KR 890011023A KR 910002468 A KR910002468 A KR 910002468A
Authority
KR
South Korea
Prior art keywords
antibody
receptor
human interleukin
human
interleukin
Prior art date
Application number
KR1019890011023A
Other languages
English (en)
Other versions
KR0135603B1 (ko
Inventor
타다미쯔 기시모토
Original Assignee
타다미쯔 기시모토
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Filing date
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Application filed by 타다미쯔 기시모토 filed Critical 타다미쯔 기시모토
Publication of KR910002468A publication Critical patent/KR910002468A/ko
Application granted granted Critical
Publication of KR0135603B1 publication Critical patent/KR0135603B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/0066—Use of inorganic compounding ingredients
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/0014—Use of organic additives
    • C08J9/0023—Use of organic additives containing oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/34—Silicon-containing compounds
    • C08K3/346—Clay
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/34—Silicon-containing compounds
    • C08K3/36—Silica
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2325/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Derivatives of such polymers
    • C08J2325/02—Homopolymers or copolymers of hydrocarbons
    • C08J2325/04—Homopolymers or copolymers of styrene
    • C08J2325/06—Polystyrene
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S521/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S521/908—Nucleating agent for cellular product

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Extrusion Moulding Of Plastics Or The Like (AREA)
  • Floor Finish (AREA)
  • Molding Of Porous Articles (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

내용 없음

Description

인간 인터로이킨-6 수용체에 대한 항체
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 T-세포의 반응성을 표시하며,
제2도는 내부적으로 라벨 붙인 U226 세포를 용해시켜서 얻은 결과이고,
제3도는 PM1과 MT18 항체의 억제효과를 보여준다.

Claims (14)

  1. 인간 인터로이킨-6 수용체에 특이하게 결합할 수 있는 인간 인터로이킨-6 수용체에 대한 항체.
  2. 제1항에 있어서, 항체가 모노클로날 항체인 항체.
  3. 제2항에 있어서, 항체가 인간 인터로이킨-6수용체에 결합하기 위한 인간 인터로이킨-6와 경쟁하는 항체.
  4. 제3항에 있어서, 항체가 PM1 항체인 항체.
  5. 제2항에 있어서, 항체가 인간 인터로이킨-6수용체에 결합하기 위해서 인간 인터로이킨-6와 경쟁하지않는 항체.
  6. 제5항에 있어서, 항체가 MT18 항체인 항체.
  7. 제1항에 있어서, 항체가 폴리클로날 항체인 항체.
  8. 제1항 내지 제7항의 어느 하나에 있어서, 항체가 아미노산을 알파벳자로 표시하여(N-말단) KTSMHPPYS LGQLVP(C-말단)으로 표시되는 인간 일터로이킨-6 수용체의 일부를 인식하는 항체.
  9. 제2항에 기술한 모노클로날 항체를 생산하는 히브리도마.
  10. 인간 인터로이킨-6 수용체 항원으로 포유류를 면역시키고, 포유류로부터 면역체를 얻고, 면역체를 골수종 세포와 융합하고 그리고 융합 세포로부터 인간 인터로이킨-6 수용체를 인식할 수 있는 히브리도마를 클로닝하는 것으로 되는 히브리도마의 제조방법.
  11. 제10항에 있어서, 인터로이킨-6 수용체 항원이 고체 캐리어에 결합된 인간 인터로이킨-6 수용체인 방법.
  12. 제9항에서 기술한 히브리도마 또는 제10항 또는 제11항에서 기술한 방법으로 제조된 히브리도마를 배양하고, 배지로부터 인간 인터로이킨-6수용체를 인식할 수 있는 모노 클로날 항체를 회수하는 것으로 되는 항-인간인터로이킨-6 수용체 항체의 제조방법.
  13. 포유류를 인간 일터로이킨-6 수용체 항원으로 면역시키고 그리고 면역된 동물로부터 인터로이킨-6수용체를 인식할 수 있는 폴리클로날 항체를 회수하는 것으로 항-인간 인터로이킨-6수용체 폴리클로날 항체의 제조방법.
  14. 제13항에 있어서, 인간 인터로이킨-6 수용체 항원이 아미노산을 알파벳 한자로 표시하여 (N-말단) KTSMHPPYS LGQLVP(C-말단)으로 표시되는 순서를 가지는 펩티드가 중합체 캐리어에 공액된 콤프렉스인 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890011023A 1988-08-02 1990-07-20 압출된 합성수지 발포체 및 이의 제조방법 KR0135603B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP88-193717 1988-08-02
JP19371788 1988-08-02
JP17092889 1989-06-30
JP89-170923 1989-06-30
JP1-186016 1989-07-20

Publications (2)

Publication Number Publication Date
KR910002468A true KR910002468A (ko) 1991-02-25
KR0135603B1 KR0135603B1 (ko) 1998-04-23

Family

ID=26493790

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019890011023Q KR900003262A (ko) 1988-08-02 1989-08-02 압출된 합성수지 발포체 및 이의 제조방법
KR1019890011023A KR0135603B1 (ko) 1988-08-02 1990-07-20 압출된 합성수지 발포체 및 이의 제조방법

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019890011023Q KR900003262A (ko) 1988-08-02 1989-08-02 압출된 합성수지 발포체 및 이의 제조방법

Country Status (16)

Country Link
US (2) US4990542A (ko)
EP (1) EP0353701B1 (ko)
JP (1) JPH03109445A (ko)
KR (2) KR900003262A (ko)
AR (1) AR243565A1 (ko)
AT (1) ATE151094T1 (ko)
CA (1) CA1330155C (ko)
DE (1) DE68927924T2 (ko)
DK (1) DK376789A (ko)
ES (1) ES2102349T3 (ko)
FI (1) FI101212B1 (ko)
HU (1) HU216158B (ko)
IS (1) IS1537B (ko)
MX (1) MX170394B (ko)
NO (1) NO175211C (ko)
NZ (1) NZ230152A (ko)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IS1537B (is) * 1988-08-02 1994-01-28 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Útþanið tilbúið viðarkvoðufrauð (gerviresínfroða)og aðferð við framleiðslu þess
US5098782A (en) * 1988-10-13 1992-03-24 Applied Extrusion Technologies, Inc. Extruded ethylenic polymer foam containing both open and closed cells
US5277515A (en) * 1988-10-13 1994-01-11 Applied Extrusion Technologies, Inc. Extruded ethylenic polymer foam containing both open and closed cells
NO177791C (no) * 1990-02-01 1995-11-22 Kanegafuchi Chemical Ind Fremgangsmåte for fremstilling av polystyrenskum
GB9018640D0 (en) * 1990-08-24 1990-10-10 Dow Vertriebs Gmbh Insect resistant foam body useful in farm buildings
US5149726A (en) * 1990-08-24 1992-09-22 The Dow Chemical Company Insect resistant foam body useful in farm buildings
US5158986A (en) 1991-04-05 1992-10-27 Massachusetts Institute Of Technology Microcellular thermoplastic foamed with supercritical fluid
US5106882A (en) * 1991-05-28 1992-04-21 The Dow Chemical Company Insulating alkenyl aromatic polymer foam
JP3369562B2 (ja) * 1992-06-09 2003-01-20 ザ ダウ ケミカル カンパニー アルケニル芳香族ポリマーフォームおよび該フォームの製造法
US5369137A (en) * 1992-06-09 1994-11-29 The Dow Chemical Company Flexible bimodal foam structures
US5332761A (en) * 1992-06-09 1994-07-26 The Dow Chemical Company Flexible bimodal foam structures
US5380767A (en) * 1992-10-23 1995-01-10 The Dow Chemical Company Foamable gel with an aqueous blowing agent expandable to form a unimodal styrenic polymer foam structure and a process for making the foam structure
JP2558421B2 (ja) * 1992-12-21 1996-11-27 株式会社 マブチ 合成樹脂体の製造方法
JPH0667404U (ja) * 1993-03-10 1994-09-22 株式会社ベスト 容器回収ボックス
US5866053A (en) * 1993-11-04 1999-02-02 Massachusetts Institute Of Technology Method for providing continuous processing of microcellular and supermicrocellular foamed materials
US5830740A (en) * 1994-07-20 1998-11-03 Research Corporation Technologies, Inc. Serine protease operative between 75°C. and 103°C.
DE19542060A1 (de) * 1995-10-06 1997-04-10 Gefinex Gmbh Treibmittel für PP- und PS-Kunststoffschaum
US5776389A (en) * 1996-06-20 1998-07-07 The Dow Chemical Company Process for making an alkenyl aromatic polymer foam having enlarged cell size
JP4307573B2 (ja) 1998-04-23 2009-08-05 株式会社カネカ スチレン系樹脂押出発泡体およびその製造方法
CA2356917A1 (en) 1999-10-27 2001-05-03 Kaneka Corporation Extruded styrene resin foams and methods for producing the same
US6528548B2 (en) 2000-01-14 2003-03-04 Kaneka Corporation Synthetic thermoplastic resin extruded foams and methods for producing the same
JP4100850B2 (ja) * 2000-01-14 2008-06-11 株式会社カネカ ポリスチレン系樹脂押出発泡体及びその製造方法
JP2004512406A (ja) * 2000-10-24 2004-04-22 ダウ　グローバル　テクノロジーズ　インコーポレイティド 水を必要としないマルチモーダル熱可塑性ポリマーフォームの調製方法およびそれより調製されたフォーム
JP4272069B2 (ja) 2002-01-04 2009-06-03 ダウ グローバル テクノロジーズ インコーポレイティド 吸収性クレイを含む多峰性ポリマー発泡体
US7951449B2 (en) * 2002-06-27 2011-05-31 Wenguang Ma Polyester core materials and structural sandwich composites thereof
DE10241298A1 (de) * 2002-09-04 2004-03-18 Basf Ag Verfahren zur Herstellung von Polystyrolschaumpartikeln mit niedriger Schüttdichte
JP4422985B2 (ja) * 2003-07-25 2010-03-03 積水化成品工業株式会社 スチレン系樹脂発泡シート、成形容器およびその製造方法
US9359481B2 (en) 2003-11-26 2016-06-07 Owens Corning Intellectual Capital, Llc Thermoplastic foams and method of forming them using nano-graphite
US8568632B2 (en) 2003-11-26 2013-10-29 Owens Corning Intellectual Capital, Llc Method of forming thermoplastic foams using nano-particles to control cell morphology
US7140936B2 (en) * 2004-02-12 2006-11-28 John Roberts Island swim raft
JP5306572B2 (ja) * 2005-07-22 2013-10-02 株式会社カネカ スチレン系樹脂発泡体およびその製造方法
JP2007308627A (ja) * 2006-05-19 2007-11-29 Kaneka Corp スチレン系樹脂押出発泡体
JP4990559B2 (ja) * 2006-06-01 2012-08-01 株式会社カネカ スチレン系樹脂押出発泡体及びその製造方法
JP2007321075A (ja) * 2006-06-01 2007-12-13 Kaneka Corp スチレン系樹脂押出発泡体
US8889748B2 (en) 2010-06-01 2014-11-18 Basf Se Process for producing expandable styrene polymer compositions
WO2011151301A1 (de) * 2010-06-01 2011-12-08 Basf Se Verfahren zur herstellung von expandierbaren styrolpolymer-zusammensetzungen
US8889752B2 (en) * 2010-06-11 2014-11-18 Fina Technology, Inc. Foamed articles exhibiting improved thermal properties
JP5814785B2 (ja) * 2011-12-28 2015-11-17 化成工業株式会社 シール材用発泡ゴム成形体及びその製造方法
CN104892464A (zh) * 2015-05-21 2015-09-09 杭州海虹精细化工有限公司 一种简易控制adc产品粒径的新方法
CN106893259B (zh) * 2015-12-17 2019-08-27 广东生益科技股份有限公司 一种热固性树脂组合物及其用途
KR102077469B1 (ko) * 2015-12-21 2020-04-03 한국건설기술연구원 단열재 및 이의 제조 방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB916776A (en) * 1959-05-13 1963-01-30 Monsanto Chemicals Foamable thermoplastic polymers
US3962154A (en) * 1971-06-01 1976-06-08 Standard Oil Company Method for producing an improved molded thermoplastic article
BE791957A (fr) * 1971-11-29 1973-05-28 Rhone Progil Procede de preparation de profiles de structure cellulaire par extrusion de compositions polymeres thermoplastiques expansibles
JPS5135224B2 (ko) * 1972-07-21 1976-10-01
US4048208A (en) * 1975-12-31 1977-09-13 Arco Polymers, Inc. Method for preparing improved expanded polystyrene sheet
US4048272A (en) * 1976-01-02 1977-09-13 Arco Polymers, Inc. Method for preparing improved expanded polystyrene sheet
JPS57197132A (en) * 1981-05-29 1982-12-03 Sumitomo Chem Co Ltd Manufacture of polypropylene foam
DE3131446A1 (de) * 1981-08-07 1983-02-24 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von feinzelligen schaumstoffen aus styrolpolymerisaten
US4455272A (en) * 1982-03-29 1984-06-19 Standard Oil Company (Indiana) Method of extruding a polystyrene foam using both a physical blowing agent and water
US4473665A (en) * 1982-07-30 1984-09-25 Massachusetts Institute Of Technology Microcellular closed cell foams and their method of manufacture
US4438224A (en) * 1982-09-29 1984-03-20 The Dow Chemical Company Method for the preparation of styrene polymer foam and foam prepared thereby
US4559367A (en) * 1985-04-12 1985-12-17 The Dow Chemical Company Combination blowing agent and filler for thermoplastic foams
IS1537B (is) * 1988-08-02 1994-01-28 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Útþanið tilbúið viðarkvoðufrauð (gerviresínfroða)og aðferð við framleiðslu þess

Also Published As

Publication number Publication date
FI101212B (fi) 1998-05-15
IS3497A7 (is) 1990-02-03
ES2102349T3 (es) 1997-08-01
JPH0549701B2 (ko) 1993-07-27
NZ230152A (en) 1992-08-26
HU216158B (hu) 1999-04-28
FI893651A0 (fi) 1989-08-01
CA1330155C (en) 1994-06-14
NO893110L (no) 1990-03-23
DE68927924D1 (de) 1997-05-07
DK376789A (da) 1990-02-03
IS1537B (is) 1994-01-28
JPH03109445A (ja) 1991-05-09
US4990542A (en) 1991-02-05
DE68927924T2 (de) 1997-09-18
EP0353701A2 (en) 1990-02-07
AR243565A1 (es) 1993-08-31
NO175211B (ko) 1994-06-06
HUT56863A (en) 1991-10-28
EP0353701A3 (en) 1991-01-23
KR0135603B1 (ko) 1998-04-23
KR900003262A (ko) 1990-03-26
ATE151094T1 (de) 1997-04-15
FI101212B1 (fi) 1998-05-15
DK376789D0 (da) 1989-08-01
US5064874A (en) 1991-11-12
FI893651A (fi) 1990-02-03
MX170394B (es) 1993-08-19
EP0353701B1 (en) 1997-04-02
NO893110D0 (no) 1989-08-01
NO175211C (no) 1994-09-14

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