GB2199833A - Preparation of monoclonal antibodies - Google Patents

Preparation of monoclonal antibodies

Info

Publication number
GB2199833A
GB2199833A GB08804802A GB8804802A GB2199833A GB 2199833 A GB2199833 A GB 2199833A GB 08804802 A GB08804802 A GB 08804802A GB 8804802 A GB8804802 A GB 8804802A GB 2199833 A GB2199833 A GB 2199833A
Authority
GB
United Kingdom
Prior art keywords
monoclonal antibody
ligand
secondary monoclonal
preparation
monoclonal antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB08804802A
Other versions
GB8804802D0 (en
Inventor
Dr Colin Henry Self
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antibody Technology Ltd
Original Assignee
Antibody Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibody Technology Ltd filed Critical Antibody Technology Ltd
Publication of GB8804802D0 publication Critical patent/GB8804802D0/en
Publication of GB2199833A publication Critical patent/GB2199833A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A method for producing a secondary monoclonal antibody against a complex of a ligand and a binding protein against said ligand which secondary monoclonal antibody is not an antibody against the ligand or against its binding protein which method comprises introducing the complex directly to immunocompetent cells, thereafter fusing said immunocompetent cells with neoplastic perpetuating cells and selecting and growing hybridomas capable of producing said secondary monoclonal antibody and recovering said secondary monoclonal antibody produced thereby.
GB08804802A 1986-07-02 1987-07-01 Preparation of monoclonal antibodies Pending GB2199833A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868616174A GB8616174D0 (en) 1986-07-02 1986-07-02 Monoclonal antibodies
PCT/GB1987/000461 WO1988000240A1 (en) 1986-07-02 1987-07-01 Preparation of monoclonal antibodies

Publications (2)

Publication Number Publication Date
GB8804802D0 GB8804802D0 (en) 1988-03-30
GB2199833A true GB2199833A (en) 1988-07-20

Family

ID=10600472

Family Applications (2)

Application Number Title Priority Date Filing Date
GB868616174A Pending GB8616174D0 (en) 1986-07-02 1986-07-02 Monoclonal antibodies
GB08804802A Pending GB2199833A (en) 1986-07-02 1987-07-01 Preparation of monoclonal antibodies

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB868616174A Pending GB8616174D0 (en) 1986-07-02 1986-07-02 Monoclonal antibodies

Country Status (3)

Country Link
AU (1) AU7649187A (en)
GB (2) GB8616174D0 (en)
WO (1) WO1988000240A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223441A (en) * 1986-10-09 1993-06-29 Syntex (U.S.A.) Inc. Receptors for immune complexes
WO1991019001A1 (en) * 1990-05-25 1991-12-12 British Technology Group Ltd Immunodiagnostic assay for rheumatoid arthritis
AU656181B2 (en) * 1991-05-03 1995-01-27 Pasteur Sanofi Diagnostics Heterobifunctional antibodies possessing dual catalytic and specific antigen binding properties and methods using them
GB9125024D0 (en) * 1991-11-25 1992-01-22 Kirby Julian Rheumatoid arthritus treatment
US5837686A (en) * 1991-11-25 1998-11-17 Peptide Therapeutics Limited Peptides and antibodies for treatment of rheumatoid arthritis
JPH11153599A (en) * 1997-11-21 1999-06-08 Dai Ichi Pure Chem Co Ltd Immunoassay
GB0707870D0 (en) 2007-04-23 2007-05-30 Selected Antibodies Ltd Assay Devices and Methods and Components for use Therein

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8408193D0 (en) * 1984-03-30 1984-05-10 Cambridge Patent Dev Antibodies

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL ABSTRACTS, VOLUME 76, NO. 6, 1983 PAGE 4524 ABSTRACT 41616, *
BIOLOGICAL ABSTRACTS, VOLUME 78, NO. 7, 1984, PAGE 5803, ABSTRACT 51560, *
BIOLOGICAL ABSTRACTS, VOLUME 79, NO. 10, 1985, PAGE AB-482, ABSTRACT 86692, *
BIOLOGICAL ABSTRACTS, VOLUME 79, NO. 12, 1985, PAGE AB-456, ABSTRACT 104956, *
WO A 85/04422 *

Also Published As

Publication number Publication date
GB8616174D0 (en) 1986-08-06
AU7649187A (en) 1988-01-29
WO1988000240A1 (en) 1988-01-14
GB8804802D0 (en) 1988-03-30

Similar Documents

Publication Publication Date Title
ES8206856A1 (en) Method for the determination of antigens with the aid of two or more monoclonal antibodies.
AU3066489A (en) Monoclonal antibodies against glycated albumin, hybrid cell lines producing these antibodies, and use therefore
ZA874558B (en) Monoclonal antibodies to unreduced,nonenzymatically-glycated proteins
GB2128630A (en) Method of affinity purification employing monoclonal antibodies
IL73437A (en) Method and test kit for detecting immune(clq)complexes in human serum by means of a mouse monoclonal antibody
NZ222309A (en) Antibodies (including chimeric antibodies) to a human tumour antigen, polynucleotides encoding them, detection of the antigen by immunoassay and imaging methods and also cell killing methods
GB8504104D0 (en) Hcmv monoclonal antibodies
GB8609058D0 (en) Monoclonal antibodies
DE3480494D1 (en) Method and reagent for use in the assay of pivka-ii
GB2199833A (en) Preparation of monoclonal antibodies
AU635243B2 (en) Immunoassay of human osteocalcin, reagent and kit therefor, antihuman osteocalcin antibody, hybridoma producing said antibody, and method of producing said antibody
EP0287397A3 (en) Monoclonal antibody specific to human pancreatic phospholipase a2
JPS57208458A (en) Labeled antibody for immunochemical measurement
ES2061664T3 (en) MONOCLONAL ANTIBODIES RECOGNIZING ALFA-HANP AND CORRESPONDING HYBRIDOMES, THEIR PREPARATION AND USE.
EP0155172A3 (en) Anti-human lung cancer monoclonal antibodies
ES2061973T3 (en) MONOCLONAL ANTIBODIES RECOGNIZING THE N-TERMINAL REGION OF AURICULAR NATRIURETIC POLYPEPTIDE, ITS PREPARATION AND USE.
DE3273844D1 (en) Procedure for immunological determinations using two antibodies, the second antibody being purified by affinity chromatography, and supports therefor
EP0315447A3 (en) Method of immunological measurement of human protein s and reagent and kit therefor
EP0141616A3 (en) Hybrid cell lines producing monoclonal antibodies directed against trichomonas vaginalis determinants
DK329789A (en) MONOCLONAL ANTIBODY
EP0131415A3 (en) Monoclonal antibodies, processes for their preparation and methods for their use
ZA861551B (en) Process and reagent for the determination of the follicle-stimulating hormone and monoclonal antibodies suitable therefor
EP0369797A3 (en) A monoclonal antibody recognizing a reg protein
DE3375516D1 (en) Monoclonal antibody specific for human blood group antigen k (cellano), and hybridoma cell lines producing these monoclonal antibodies
EP0190049A3 (en) Method for selecting hybridomas producing antibodies specific to inaccessible cell surface antigens