KR900009675A - 신규 백금 착화합물 - Google Patents
신규 백금 착화합물 Download PDFInfo
- Publication number
- KR900009675A KR900009675A KR1019890019099A KR890019099A KR900009675A KR 900009675 A KR900009675 A KR 900009675A KR 1019890019099 A KR1019890019099 A KR 1019890019099A KR 890019099 A KR890019099 A KR 890019099A KR 900009675 A KR900009675 A KR 900009675A
- Authority
- KR
- South Korea
- Prior art keywords
- trans
- platinum complex
- new platinum
- diaminocyclohexane
- cis
- Prior art date
Links
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 title claims 6
- 229910052697 platinum Inorganic materials 0.000 title claims 3
- SSJXIUAHEKJCMH-UHFFFAOYSA-N cyclohexane-1,2-diamine Chemical compound NC1CCCCC1N SSJXIUAHEKJCMH-UHFFFAOYSA-N 0.000 claims 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F17/00—Metallocenes
- C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic System
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (2)
- 일반식(Ⅰ)의 백금 착화합물.식중, R1및 R2는 같거나 다를 수 있으며, 각각 메틸기 또는 에틸기를 나타내고, 1,2-디아미노시클로헥산의 입체 배위는 시스-, 트랜스-1-, 트랜스-d-, 또는 트랜스-dl- 중 하나이다.
- 일반식(Ⅰ)의 백금 착화합물을 유효성분으로 함유하는 항종양제.식중, R1및 R2는 같거나 다를 수 있으며, 각각 메틸기 또는 에틸기를 나타내고, 1, 2-디아미노시클로헥산의 입체 배위는 시스-, 트랜스-1-, 트랜스-d, 또는 트랜스-dl- 중 하나이다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33025188 | 1988-12-27 | ||
| JP330251/88 | 1988-12-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR900009675A true KR900009675A (ko) | 1990-07-05 |
Family
ID=18230550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019890019099A KR900009675A (ko) | 1988-12-27 | 1989-12-21 | 신규 백금 착화합물 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5008419A (ko) |
| EP (1) | EP0376076A1 (ko) |
| KR (1) | KR900009675A (ko) |
| CA (1) | CA2005851A1 (ko) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1216687B (it) * | 1988-04-01 | 1990-03-08 | Boehringer Biochemia Srl | Complessi di platino (ii), loro preparazione e impiego come antitumorali. |
| JPH0776230B2 (ja) * | 1992-01-13 | 1995-08-16 | 田中貴金属工業株式会社 | 白金化合物の製造方法 |
| JPH09278785A (ja) * | 1996-04-10 | 1997-10-28 | Tanaka Kikinzoku Kogyo Kk | 白金化合物の製造方法 |
| DK0801070T3 (da) * | 1996-04-10 | 2003-05-19 | Debiopharm Sa | Fremgangsmåde til fremstilling af platinforbindelse |
| JP3154399B2 (ja) * | 1996-07-04 | 2001-04-09 | デビオファーム エス．アー． | 白金化合物の製造方法 |
| DE102004005906B3 (de) * | 2004-02-05 | 2005-09-29 | W.C. Heraeus Gmbh | Verfahren zur Herstellung von 1,2-Diaminocylohexan-Platin(II)-Komplexen |
| US7208616B2 (en) | 2004-07-12 | 2007-04-24 | Sicor, Inc. | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6041077B2 (ja) * | 1976-09-06 | 1985-09-13 | 喜徳 喜谷 | １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体 |
| SE7903361L (sv) * | 1978-04-20 | 1979-10-21 | Johnson Matthey Co Ltd | Kompositioner innehallande platina |
| GB8328218D0 (en) * | 1983-10-21 | 1983-11-23 | Johnson Matthey Plc | Oral compositions |
| JPS61255943A (ja) * | 1985-05-10 | 1986-11-13 | Human Ind Corp | 炭化水素フオ−ムの製造方法 |
| JPS63203692A (ja) * | 1987-02-19 | 1988-08-23 | Nippon Kayaku Co Ltd | 新規白金錯体 |
| US4904809A (en) * | 1987-09-25 | 1990-02-27 | Ss Pharmaceutical Co., Ltd. | Platinum complex |
-
1989
- 1989-12-14 EP EP89123140A patent/EP0376076A1/en not_active Withdrawn
- 1989-12-18 CA CA002005851A patent/CA2005851A1/en not_active Abandoned
- 1989-12-18 US US07/451,637 patent/US5008419A/en not_active Expired - Fee Related
- 1989-12-21 KR KR1019890019099A patent/KR900009675A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US5008419A (en) | 1991-04-16 |
| CA2005851A1 (en) | 1990-06-27 |
| EP0376076A1 (en) | 1990-07-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |