KR890004697A - 멜라닌 생성 억제 외용약제 - Google Patents

멜라닌 생성 억제 외용약제 Download PDF

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Publication number
KR890004697A
KR890004697A KR1019880012451A KR880012451A KR890004697A KR 890004697 A KR890004697 A KR 890004697A KR 1019880012451 A KR1019880012451 A KR 1019880012451A KR 880012451 A KR880012451 A KR 880012451A KR 890004697 A KR890004697 A KR 890004697A
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South Korea
Prior art keywords
kojic acid
acid
kojic
group
ester
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KR1019880012451A
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English (en)
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KR930010578B1 (ko
Inventor
신기치 하다에
Original Assignee
진나이 쓰네오
산쇼오 세이야쿠 가부시키가이샤
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Publication of KR890004697A publication Critical patent/KR890004697A/ko
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Publication of KR930010578B1 publication Critical patent/KR930010578B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음

Description

멜라닌 생성 억제 외용약제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 코오지산 또는 그의 에스테르 및 비타민 C 또는 그의 유도체로 구성되는 멜라닌 생성 억제 외용 약제.
  2. 제1항에 있어서, 코지산은 다음식의 화합물이며
    여기서 R1및 R2는 동이하거나 상이할 수 있고 R1과 R2는 3-20개 탄소원자의 아실 그룹이거나 R1과 R2중 하나는 수소이고 다른 하나는 3-20개 탄소원자의 아실 그룹인 것을 특징으로 하는 멜라닌 생성 억제 외용 약제.
  3. 제2항에 있어서, 코지산 에스테르는 코지산 모노부리 레이트, 코지산 모노카프레이트, 코지산 모노-팔미테이트, 코지산 모노그테아르에이트, 코지산 모노신나모에이트, 코지산 모노벤조에이트, 코지산 디부티레이트, 코지산 디팔미테이트, 코지산 디스테아르에이트, 코지산 디올레이트 및 그의 혼합물로 구성되는 그룹으로부터 선택된 성분인 것을 특징으로 하는 멜라닌 생성 억제 외용 약제.
  4. 제1항에 있어서, 비타민 C의 유도체는 L-아스코르브산의 알킬 에스테르, L-아스코르브산의 인산염, L-아스코르브 산의 황산염, 그의 금속염 및 혼합물로 구성되는 그룹으로부터 선택된 성분인 것을 특징으로 하는 멜라닌 생성 억제 외용 약제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880012451A 1987-09-25 1988-09-25 멜라닌 생성 억제 외용약제 KR930010578B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP?62-241965 1987-09-25
JP62-241965 1987-09-25
JP62241965A JPS6483010A (en) 1987-09-25 1987-09-25 Melanization inhibitory drug for external use

Publications (2)

Publication Number Publication Date
KR890004697A true KR890004697A (ko) 1989-05-09
KR930010578B1 KR930010578B1 (ko) 1993-10-30

Family

ID=17082212

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880012451A KR930010578B1 (ko) 1987-09-25 1988-09-25 멜라닌 생성 억제 외용약제

Country Status (6)

Country Link
US (1) US4919921A (ko)
EP (1) EP0308918A1 (ko)
JP (1) JPS6483010A (ko)
KR (1) KR930010578B1 (ko)
AU (1) AU606200B2 (ko)
DE (1) DE3832218A1 (ko)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS638310A (ja) * 1986-06-27 1988-01-14 Sansho Seiyaku Kk メラニン生成抑制外用薬剤
JP2663136B2 (ja) * 1988-05-02 1997-10-15 有限会社野々川商事 美白化粧料
JP2977865B2 (ja) * 1989-06-23 1999-11-15 三省製薬株式会社 真皮部位に発症する色素沈着症治療剤
US5409693A (en) * 1989-10-12 1995-04-25 Perricone; Nicholas V. Method for treating and preventing sunburn and sunburn damage to the skin
DE4026787A1 (de) * 1990-08-24 1992-02-27 Basf Ag Verfahren zur herstellung von kaliummagnesium-l-ascorbat-2-phosphat
TW197375B (ko) * 1990-11-19 1993-01-01 Hayashibara Biochem Lab
US5308621A (en) * 1991-02-18 1994-05-03 Commonwealth Scientific And Industrial Research Organisation Ascorbic acid composition and transdermal administration method
US5538752A (en) * 1992-08-04 1996-07-23 Regents Of The Univ. Of Minnesota Melanin compositions and uses thereof and resulting products
ES2151498T3 (es) * 1993-01-19 2001-01-01 Nicholas V Dr Perricone Composiciones para aplicacion topica a la piel para el tratamiento y/o prevencion de la lesion en la piel inducida por radiacion.
JP3529811B2 (ja) * 1993-06-30 2004-05-24 三省製薬株式会社 皮膚外用剤
US5411741A (en) * 1993-07-29 1995-05-02 Zaias; Nardo Method and composition for skin depigmentation
JP3566739B2 (ja) * 1993-09-30 2004-09-15 三省製薬株式会社 皮膚外用剤の安定化方法
US5874463A (en) * 1994-10-24 1999-02-23 Ancira; Margaret Hydroxy-kojic acid skin peel
US6162450A (en) * 1995-05-15 2000-12-19 Avon Products, Inc. Uses of ascorbyl-phosphoryl-cholesterol and compositions for practicing same
US5922335A (en) * 1995-05-15 1999-07-13 Avon Products, Inc. Uses for ascorbyl-phosphoryl-cholesterol in topical compositions
US5747006A (en) * 1997-05-14 1998-05-05 Amway Corporation Skin whitener composition containing acerola cherry fermentate
US6074647A (en) * 1998-04-14 2000-06-13 Amway Corporation Method of increasing skin cell renewal rate using acerola cherry fermentate
US6110966A (en) * 1998-02-20 2000-08-29 Medi-Cell Laboratories, Inc. Triple action complex
US5824327A (en) * 1998-04-06 1998-10-20 Whittemore; Jerry Kojic dipalmitate skin whitening comestic composition
JP2000095641A (ja) * 1998-09-25 2000-04-04 Kanebo Ltd 美白化粧料
US6184247B1 (en) 1999-05-21 2001-02-06 Amway Corporation Method of increasing cell renewal rate
US7025957B2 (en) * 2002-09-06 2006-04-11 Desert Whale Jojoba Company Composition and method to whiten skin
US7429391B2 (en) * 2004-01-30 2008-09-30 Access Business Group International Llc Holistic composition and method for reducing skin pigmentation
WO2007041230A2 (en) * 2005-09-30 2007-04-12 Omp, Inc. Stable ascorbic acid compositions
US20070269534A1 (en) * 2006-02-02 2007-11-22 Ramirez Jose E Methods of treating skin to enhance therapeutic treatment thereof
US20070178058A1 (en) * 2006-02-02 2007-08-02 Ramirez Jose E Methods of using stable ascorbic acid compositions
SG172811A1 (en) * 2008-12-31 2011-08-29 Revance Therapeutics Inc Compositions and methods for treating hyperpigmentation
WO2016053289A1 (en) * 2014-09-30 2016-04-07 Avon Products, Inc. Topical compositions and methods for skin lightening

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5318739A (en) * 1976-08-03 1978-02-21 Sansho Seiyaku Kk Decolorant for external application
DE2744976C2 (de) * 1977-10-06 1983-11-03 Elisabeth Frucht, Fabrik kosmetischer Präparate, 3016 Seelze Präparat gegen Sommersprossen
JPS567710A (en) * 1979-06-28 1981-01-27 Sansho Seiyaku Kk Whitening cosmetic
JPS5822151B2 (ja) * 1979-10-22 1983-05-06 三省製薬株式会社 コウジ酸のジエステル化物
JPS609722B2 (ja) * 1979-12-05 1985-03-12 三省製薬株式会社 色白化粧料
JPS6010005B2 (ja) * 1982-08-20 1985-03-14 三省製薬株式会社 色白化粧料
JPS59157009A (ja) * 1983-02-25 1984-09-06 Yakurigaku Chuo Kenkyusho:Kk メラニン生成抑制外用剤
JPS61100509A (ja) * 1984-10-19 1986-05-19 Shizenbi Shiyouyaku Kk ゲル状美白化粧料
US4818521A (en) * 1985-04-18 1989-04-04 Sunstar Kabushiki Kaisha Emulsion cosmetic stably containing vitamin C
JPH0696509B2 (ja) * 1985-11-06 1994-11-30 ポーラ化成工業株式会社 化粧料
JP2565513B2 (ja) * 1987-09-25 1996-12-18 三省製薬株式会社 メラニン生成抑制外用薬剤

Also Published As

Publication number Publication date
DE3832218A1 (de) 1989-04-13
JPS6483010A (en) 1989-03-28
KR930010578B1 (ko) 1993-10-30
AU606200B2 (en) 1991-01-31
EP0308918A1 (en) 1989-03-29
US4919921A (en) 1990-04-24
AU2152388A (en) 1989-04-06

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