KR880701721A - 7-diazaguanine as an immunomodulator - Google Patents

7-diazaguanine as an immunomodulator

Info

Publication number
KR880701721A
KR880701721A KR1019880700721A KR880700721A KR880701721A KR 880701721 A KR880701721 A KR 880701721A KR 1019880700721 A KR1019880700721 A KR 1019880700721A KR 880700721 A KR880700721 A KR 880700721A KR 880701721 A KR880701721 A KR 880701721A
Authority
KR
South Korea
Prior art keywords
diazaguanine
immunomodulator
Prior art date
Application number
KR1019880700721A
Other languages
Korean (ko)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR880701721A publication Critical patent/KR880701721A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
KR1019880700721A 1986-10-24 1988-06-24 7-diazaguanine as an immunomodulator KR880701721A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US92352186A 1986-10-24 1986-10-24
US8623187A 1987-08-20 1987-08-20
PCT/US1987/002727 WO1988003142A2 (en) 1986-10-24 1987-10-19 7-deazaguanines as immunomodulators

Publications (1)

Publication Number Publication Date
KR880701721A true KR880701721A (en) 1988-11-04

Family

ID=26774505

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880700721A KR880701721A (en) 1986-10-24 1988-06-24 7-diazaguanine as an immunomodulator

Country Status (9)

Country Link
EP (1) EP0327590A1 (en)
JP (1) JPH02501306A (en)
KR (1) KR880701721A (en)
AU (1) AU614947B2 (en)
CA (1) CA1294960C (en)
ES (1) ES2008756A6 (en)
FI (1) FI891870A (en)
GR (1) GR871606B (en)
WO (1) WO1988003142A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60433B1 (en) * 1986-08-26 1994-07-13 Warner Lambert Co Novel 9-deazaguanines
US4968686A (en) * 1988-04-08 1990-11-06 The Regents Of The University Of Michigan Acyclic pyrrolo [2,3-d]pyrimidine analogs as antiviral agents
USRE36187E (en) * 1988-04-08 1999-04-06 The Regents Of The University Of Michigan Acyclic pyrrolo 2,3-d!pyrimidine analogs as antiviral agents
US5047407A (en) * 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
DK0460116T3 (en) * 1989-02-27 1998-03-30 Biocryst Pharm Inc 9-substituted-8-unsubstituted-9-deazaguaniner
CA2072123C (en) * 1989-10-31 2001-06-12 John A. Secrist, Iii Inhibitors of purine nucleoside phosphorylase
US5726311A (en) * 1989-11-29 1998-03-10 Biocryst Pharmaceuticals, Inc. 7-disubstituted-methyl-4-oxo-3H,5H-pyrrolo 3,2-d!pyrimidine and pharmaceutical uses and compositions containing the same
US5248672A (en) * 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
EP0766684A4 (en) * 1994-06-09 1997-07-16 Smithkline Beecham Corp Endothelin receptor antagonists
GB201417165D0 (en) 2014-09-29 2014-11-12 Provost Fellows & Scholars College Of The Holy Undivided Trinity Of Queen Elizabeth Near Dublin Treatments for Autoimmune Disease
GB201417163D0 (en) 2014-09-29 2014-11-12 Provost Fellows & Scholars College Of The Holy Undivided Trinity Of Queen Elizabeth Near Dublin Substituted pyrimidine derivatives useful in the treatment of autoimmune diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748177A (en) * 1984-03-26 1988-05-31 Warner-Lambert Company Guanine derivatives
FR2574407B1 (en) * 1984-12-12 1987-06-05 Rhone Poulenc Sante NOVEL PYRROLO (2,3-D) PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IE60433B1 (en) * 1986-08-26 1994-07-13 Warner Lambert Co Novel 9-deazaguanines
DE3739366A1 (en) * 1987-04-10 1988-10-27 Boehringer Mannheim Gmbh DESAZA-PURIN-NUCLEOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN NUCLEIC ACID SEQUENCING AND AS AN ANTIVIRAL AGENT

Also Published As

Publication number Publication date
WO1988003142A2 (en) 1988-05-25
GR871606B (en) 1988-02-23
JPH02501306A (en) 1990-05-10
CA1294960C (en) 1992-01-28
WO1988003142A3 (en) 1988-05-19
FI891870A0 (en) 1989-04-19
AU614947B2 (en) 1991-09-19
ES2008756A6 (en) 1989-08-01
FI891870A (en) 1989-04-19
AU8328187A (en) 1988-05-25
EP0327590A1 (en) 1989-08-16

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Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application