GR871606B - 7- deazaguanines as immun omodulators - Google Patents

7- deazaguanines as immun omodulators

Info

Publication number
GR871606B
GR871606B GR871606A GR870101606A GR871606B GR 871606 B GR871606 B GR 871606B GR 871606 A GR871606 A GR 871606A GR 870101606 A GR870101606 A GR 870101606A GR 871606 B GR871606 B GR 871606B
Authority
GR
Greece
Prior art keywords
omodulators
deazaguanines
immun
immun omodulators
Prior art date
Application number
GR871606A
Other languages
Greek (el)
Inventor
Thomas Charles Malone
Jagadish Chandra Sircar
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of GR871606B publication Critical patent/GR871606B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
GR871606A 1986-10-24 1987-10-19 7- deazaguanines as immun omodulators GR871606B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92352186A 1986-10-24 1986-10-24
US8623187A 1987-08-20 1987-08-20

Publications (1)

Publication Number Publication Date
GR871606B true GR871606B (en) 1988-02-23

Family

ID=26774505

Family Applications (1)

Application Number Title Priority Date Filing Date
GR871606A GR871606B (en) 1986-10-24 1987-10-19 7- deazaguanines as immun omodulators

Country Status (9)

Country Link
EP (1) EP0327590A1 (en)
JP (1) JPH02501306A (en)
KR (1) KR880701721A (en)
AU (1) AU614947B2 (en)
CA (1) CA1294960C (en)
ES (1) ES2008756A6 (en)
FI (1) FI891870A (en)
GR (1) GR871606B (en)
WO (1) WO1988003142A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60433B1 (en) * 1986-08-26 1994-07-13 Warner Lambert Co Novel 9-deazaguanines
US4968686A (en) * 1988-04-08 1990-11-06 The Regents Of The University Of Michigan Acyclic pyrrolo [2,3-d]pyrimidine analogs as antiviral agents
USRE36187E (en) * 1988-04-08 1999-04-06 The Regents Of The University Of Michigan Acyclic pyrrolo 2,3-d!pyrimidine analogs as antiviral agents
US5047407A (en) * 1989-02-08 1991-09-10 Iaf Biochem International, Inc. 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties
DK0460116T3 (en) * 1989-02-27 1998-03-30 Biocryst Pharm Inc 9-substituted-8-unsubstituted-9-deazaguaniner
CA2072123C (en) * 1989-10-31 2001-06-12 John A. Secrist, Iii Inhibitors of purine nucleoside phosphorylase
US5726311A (en) * 1989-11-29 1998-03-10 Biocryst Pharmaceuticals, Inc. 7-disubstituted-methyl-4-oxo-3H,5H-pyrrolo 3,2-d!pyrimidine and pharmaceutical uses and compositions containing the same
US5248672A (en) * 1990-11-01 1993-09-28 The Regents Of The University Of Michigan Polysubstituted benzimidazole nucleosides as antiviral agents
EP0766684A4 (en) * 1994-06-09 1997-07-16 Smithkline Beecham Corp Endothelin receptor antagonists
GB201417165D0 (en) 2014-09-29 2014-11-12 Provost Fellows & Scholars College Of The Holy Undivided Trinity Of Queen Elizabeth Near Dublin Treatments for Autoimmune Disease
GB201417163D0 (en) 2014-09-29 2014-11-12 Provost Fellows & Scholars College Of The Holy Undivided Trinity Of Queen Elizabeth Near Dublin Substituted pyrimidine derivatives useful in the treatment of autoimmune diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748177A (en) * 1984-03-26 1988-05-31 Warner-Lambert Company Guanine derivatives
FR2574407B1 (en) * 1984-12-12 1987-06-05 Rhone Poulenc Sante NOVEL PYRROLO (2,3-D) PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IE60433B1 (en) * 1986-08-26 1994-07-13 Warner Lambert Co Novel 9-deazaguanines
DE3739366A1 (en) * 1987-04-10 1988-10-27 Boehringer Mannheim Gmbh DESAZA-PURIN-NUCLEOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN NUCLEIC ACID SEQUENCING AND AS AN ANTIVIRAL AGENT

Also Published As

Publication number Publication date
WO1988003142A2 (en) 1988-05-25
JPH02501306A (en) 1990-05-10
CA1294960C (en) 1992-01-28
WO1988003142A3 (en) 1988-05-19
FI891870A0 (en) 1989-04-19
AU614947B2 (en) 1991-09-19
KR880701721A (en) 1988-11-04
ES2008756A6 (en) 1989-08-01
FI891870A (en) 1989-04-19
AU8328187A (en) 1988-05-25
EP0327590A1 (en) 1989-08-16

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