KR880003897A - 디아스테레오머의 분리 - Google Patents
디아스테레오머의 분리 Download PDFInfo
- Publication number
- KR880003897A KR880003897A KR870010244A KR870010244A KR880003897A KR 880003897 A KR880003897 A KR 880003897A KR 870010244 A KR870010244 A KR 870010244A KR 870010244 A KR870010244 A KR 870010244A KR 880003897 A KR880003897 A KR 880003897A
- Authority
- KR
- South Korea
- Prior art keywords
- boc
- diastereomeric
- isolation
- mixture
- benztin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/86—Renin inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (3)
- (1) 적어도 염을 생산하기 위하여 적당한 하나의 아민으로 혼합물에 접촉하고, (2) S,S-이성체가 우위에 있는 결정들을 얻기 위하여 한 번 또는 그 이상의 여러번을 부분적으로 결정하고 (3) 산을 재발생하는 단계로 구성하는 디아스테레오머의 혼합물로부터 Boc-벤즈틴 또는 Boc-시클로틴의 S,S-이성체를 분리하는 방법.
- 제1항에 있어서, 개시 혼합물이 Boc-벤즈틴의 디아스테레오머를 포함하는 방법.
- 제2항에 있어서, (4) Boc-시클로틴을 생성하기 위하여 (3)의 단계 생성물을 수소화하는 부가적인 단계를 포함하는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US908438 | 1986-09-16 | ||
US06/908,438 US4681972A (en) | 1986-09-16 | 1986-09-16 | Separation of diastereomers |
Publications (1)
Publication Number | Publication Date |
---|---|
KR880003897A true KR880003897A (ko) | 1988-05-31 |
Family
ID=25425803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR870010244A KR880003897A (ko) | 1986-09-16 | 1987-09-16 | 디아스테레오머의 분리 |
Country Status (15)
Country | Link |
---|---|
US (1) | US4681972A (ko) |
EP (1) | EP0260668B1 (ko) |
JP (1) | JPS6383056A (ko) |
KR (1) | KR880003897A (ko) |
AT (1) | ATE68170T1 (ko) |
AU (1) | AU594190B2 (ko) |
DE (1) | DE3773601D1 (ko) |
DK (1) | DK461987A (ko) |
ES (1) | ES2026877T3 (ko) |
FI (1) | FI873988A (ko) |
GR (1) | GR3002869T3 (ko) |
NO (1) | NO166484C (ko) |
PH (1) | PH22883A (ko) |
PT (1) | PT85722B (ko) |
ZA (1) | ZA876370B (ko) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0772167B2 (ja) * | 1986-09-04 | 1995-08-02 | サントリー株式会社 | 4―アミノ―3―ヒドロキシ酪酸誘導体の製法 |
US4681972A (en) * | 1986-09-16 | 1987-07-21 | Warner-Lambert Company | Separation of diastereomers |
US4788322A (en) * | 1987-07-31 | 1988-11-29 | Merck & Co., Inc. | Process for preparing ACHPA |
DE4333323A1 (de) * | 1993-09-30 | 1995-04-06 | Hoechst Ag | Gemische isomerer Pentansäuren, aus ihnen hergestellte Ester und deren Verwendung als Schmiermittel |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3887615A (en) * | 1974-04-03 | 1975-06-03 | Hoffmann La Roche | Novel butanoic acid derivatives |
CA1108180A (en) * | 1976-07-21 | 1981-09-01 | Hamao Umezawa | Analogs of bestatin |
FR2442227A1 (fr) * | 1978-11-25 | 1980-06-20 | Nippon Kayaku Kk | Procede de production d'acides threo-3-amino-2-hydroxybutanoylaminoacetiques |
US4650897A (en) * | 1985-05-20 | 1987-03-17 | Warner-Lambert Co. | Organic synthesis |
US4729985A (en) * | 1985-08-09 | 1988-03-08 | Pfizer Inc. | Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues |
US4681972A (en) * | 1986-09-16 | 1987-07-21 | Warner-Lambert Company | Separation of diastereomers |
-
1986
- 1986-09-16 US US06/908,438 patent/US4681972A/en not_active Expired - Fee Related
-
1987
- 1987-08-26 ZA ZA876370A patent/ZA876370B/xx unknown
- 1987-08-31 AU AU77722/87A patent/AU594190B2/en not_active Ceased
- 1987-09-04 DK DK461987A patent/DK461987A/da not_active Application Discontinuation
- 1987-09-14 JP JP62228652A patent/JPS6383056A/ja active Pending
- 1987-09-14 FI FI873988A patent/FI873988A/fi not_active Application Discontinuation
- 1987-09-15 AT AT87113502T patent/ATE68170T1/de not_active IP Right Cessation
- 1987-09-15 EP EP87113502A patent/EP0260668B1/en not_active Expired - Lifetime
- 1987-09-15 PH PH35821A patent/PH22883A/en unknown
- 1987-09-15 DE DE8787113502T patent/DE3773601D1/de not_active Expired - Fee Related
- 1987-09-15 PT PT85722A patent/PT85722B/pt not_active IP Right Cessation
- 1987-09-15 ES ES198787113502T patent/ES2026877T3/es not_active Expired - Lifetime
- 1987-09-15 NO NO873855A patent/NO166484C/no unknown
- 1987-09-16 KR KR870010244A patent/KR880003897A/ko not_active Application Discontinuation
-
1991
- 1991-10-10 GR GR91401403T patent/GR3002869T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0260668A3 (en) | 1989-09-27 |
NO166484C (no) | 1991-07-31 |
FI873988A (fi) | 1988-03-17 |
PH22883A (en) | 1989-01-19 |
PT85722A (en) | 1987-10-01 |
ZA876370B (en) | 1989-04-26 |
NO873855L (no) | 1988-03-17 |
ES2026877T3 (es) | 1992-05-16 |
NO166484B (no) | 1991-04-22 |
NO873855D0 (no) | 1987-09-15 |
AU594190B2 (en) | 1990-03-01 |
EP0260668A2 (en) | 1988-03-23 |
DE3773601D1 (de) | 1991-11-14 |
DK461987D0 (da) | 1987-09-04 |
ATE68170T1 (de) | 1991-10-15 |
US4681972A (en) | 1987-07-21 |
FI873988A0 (fi) | 1987-09-14 |
PT85722B (pt) | 1992-10-30 |
GR3002869T3 (en) | 1993-01-25 |
JPS6383056A (ja) | 1988-04-13 |
EP0260668B1 (en) | 1991-10-09 |
AU7772287A (en) | 1988-03-24 |
DK461987A (da) | 1988-03-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |