KR880001651A - 이미다조 [4,5-b] 피리딘 유도체, 그의 제조방법 및 그를 함유하는 항궤양제 - Google Patents
이미다조 [4,5-b] 피리딘 유도체, 그의 제조방법 및 그를 함유하는 항궤양제 Download PDFInfo
- Publication number
- KR880001651A KR880001651A KR1019870008092A KR870008092A KR880001651A KR 880001651 A KR880001651 A KR 880001651A KR 1019870008092 A KR1019870008092 A KR 1019870008092A KR 870008092 A KR870008092 A KR 870008092A KR 880001651 A KR880001651 A KR 880001651A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- imidazo
- carbon atoms
- hydrogen atom
- same
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (3)
- 하기 일반식(Ⅰ)로 표시되는 이미다조 〔4,5-b〕피리딘 유도체.(상기식에서, R1은 환상알킬기로서 치환되어 있어도 좋은 탄소수 1~8개의 직쇄상 혹은 분지상의 알콕시기 또는 탄소수 2~4개의 플루오로알킬옥시기를 나타내며, R2는 수소원자, 메틸기 또는 메톡시기를 나타내고, R3및 R4는 같거나 다르며, 각각 수소원자 또는 메틸기를 나타낸다)
- 하기 일반식(Ⅱ)으로 표시되는 술피드 화합물을 산화시켜 얻어지는 하기 일반식(Ⅰ)로 표시되는 이미다조 〔4,5-b〕피리딘 유도체의 제조방법.(상기식에서, R1은 환상알킬기로서 치환되어 있어도 좋은 탄소수 1~8개의 직쇄상 혹은 분지상의 알콕시기 또는 탄소수 2~4개의 플루오로알킬옥시기를 나타내며, R2는 수소원자, 메틸기 또는 메톡시기를 나타내고, R3및 R4는 같거나 다르며, 각각 수소원자 또는 메틸기를 나타낸다)
- 하기 일반식(Ⅰ)로 표시되는 이미다조 〔4,5-b〕피리딘 유도체를 유효성분으로 하는 항궤양제.(상기식에서, R1은 환상알킬기로서 치환되어 있어도 좋은 탄소수 1~8개의 직쇄상 혹은 분지상의 알콕시기 또는 탄소수 2~4개의 플루오로알킬옥시기를 나타내며, R2는 수소원자, 메틸기 또는 메톡시기를 나타내고, R3및 R4는 같거나 다르며, 각각 수소원자 또는 메틸기를 나타낸다)※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP173551 | 1986-07-25 | ||
JP17355186 | 1986-07-25 | ||
JP173551/86 | 1986-07-25 | ||
JP62133534A JPH0643426B2 (ja) | 1986-07-25 | 1987-05-30 | イミダゾ〔4,5−b〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤 |
JP133534 | 1987-05-30 | ||
JP133534/87 | 1987-05-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR880001651A true KR880001651A (ko) | 1988-04-25 |
KR940002824B1 KR940002824B1 (ko) | 1994-04-04 |
Family
ID=26467860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019870008092A KR940002824B1 (ko) | 1986-07-25 | 1987-07-24 | 이미다조[4,5-b]피리딘 유도체 및 그의 제조방법 |
Country Status (14)
Country | Link |
---|---|
US (1) | US4808596A (ko) |
EP (1) | EP0254588B1 (ko) |
JP (1) | JPH0643426B2 (ko) |
KR (1) | KR940002824B1 (ko) |
AR (1) | AR245718A1 (ko) |
AT (1) | ATE71626T1 (ko) |
AU (1) | AU598564B2 (ko) |
CA (1) | CA1329204C (ko) |
DE (1) | DE3776018D1 (ko) |
ES (1) | ES2038184T3 (ko) |
GR (1) | GR3003777T3 (ko) |
HU (1) | HU200458B (ko) |
MX (1) | MX168756B (ko) |
ZA (1) | ZA875151B (ko) |
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IL71664A (en) * | 1983-05-03 | 1987-11-30 | Byk Gulden Lomberg Chem Fab | Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same |
EP0187977B1 (en) * | 1984-12-18 | 1990-08-29 | Otsuka Pharmaceutical Co., Ltd. | Tetrahydroquinoline derivatives, process for preparing the same and anti-peptic ulcer compositions containg the same |
KR950001015B1 (ko) * | 1986-01-10 | 1995-02-07 | 닛뽕 케미화 가부시끼가이샤 | 술폭시드 유도체의 제조방법 |
IT1222412B (it) * | 1987-07-31 | 1990-09-05 | Chiesi Farma Spa | Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono |
JP2679745B2 (ja) * | 1989-06-29 | 1997-11-19 | 明治製菓株式会社 | アゾール誘導体及びそれらを有効成分とする抗潰瘍剤 |
US5200407A (en) * | 1989-06-29 | 1993-04-06 | Meiji Seika Kaburhiki Kaisha | Azole derivatives and anti-ulcerative composition containing same |
ZW1992A1 (en) * | 1991-02-25 | 1993-09-22 | Janssen Pharmaceutica Nv | 4-/(2-benzotiazolyl)methylamino/-b-/(3,4-difluorephenoxy)methyl/-1-piperidine ethanol |
NZ244301A (en) * | 1991-09-20 | 1994-08-26 | Merck & Co Inc | Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds |
PT711282E (pt) * | 1993-07-28 | 2002-11-29 | Aventis Pharma Ltd | Compostos inibidores de pde iv e de fnt |
US6051570A (en) * | 1997-05-30 | 2000-04-18 | Dr. Reddy's Research Foundation | Benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them |
AU4387799A (en) * | 1998-06-26 | 2000-01-17 | Russinsky Limited | Pyridine building blocks as intermediates in the synthesis of pharmaceutically active compounds |
US6166213A (en) * | 1998-08-11 | 2000-12-26 | Merck & Co., Inc. | Omeprazole process and compositions thereof |
US6852739B1 (en) | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
US6316020B1 (en) | 1999-08-26 | 2001-11-13 | Robert R. Whittle | Pharmaceutical formulations |
US6780880B1 (en) | 1999-08-26 | 2004-08-24 | Robert R. Whittle | FT-Raman spectroscopic measurement |
US6268385B1 (en) | 1999-08-26 | 2001-07-31 | Robert R. Whittle | Dry blend pharmaceutical formulations |
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US20050031700A1 (en) * | 2003-07-18 | 2005-02-10 | Sanatarus, Inc. | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1234058A (ko) * | 1968-10-21 | 1971-06-03 | ||
IL71664A (en) * | 1983-05-03 | 1987-11-30 | Byk Gulden Lomberg Chem Fab | Fluoroalkoxy compounds,process for their preparation and pharmaceutical compositions containing the same |
JPS6034956A (ja) * | 1983-08-04 | 1985-02-22 | Fujisawa Pharmaceut Co Ltd | 新規チアゾリウム化合物およびその製造法 |
EP0187977B1 (en) * | 1984-12-18 | 1990-08-29 | Otsuka Pharmaceutical Co., Ltd. | Tetrahydroquinoline derivatives, process for preparing the same and anti-peptic ulcer compositions containg the same |
KR950001015B1 (ko) * | 1986-01-10 | 1995-02-07 | 닛뽕 케미화 가부시끼가이샤 | 술폭시드 유도체의 제조방법 |
JPS62207271A (ja) * | 1986-03-06 | 1987-09-11 | Yamanouchi Pharmaceut Co Ltd | 2−ピリジルメチルチオ基または2−ピリジルメチルスルフイニル基で置換された縮合環化合物 |
IT1222412B (it) * | 1987-07-31 | 1990-09-05 | Chiesi Farma Spa | Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono |
-
1987
- 1987-05-30 JP JP62133534A patent/JPH0643426B2/ja not_active Expired - Lifetime
- 1987-07-14 AU AU75628/87A patent/AU598564B2/en not_active Expired
- 1987-07-14 ZA ZA875151A patent/ZA875151B/xx unknown
- 1987-07-21 CA CA000542637A patent/CA1329204C/en not_active Expired - Lifetime
- 1987-07-22 AR AR87308224A patent/AR245718A1/es active
- 1987-07-24 ES ES198787306570T patent/ES2038184T3/es not_active Expired - Lifetime
- 1987-07-24 KR KR1019870008092A patent/KR940002824B1/ko not_active IP Right Cessation
- 1987-07-24 AT AT87306570T patent/ATE71626T1/de not_active IP Right Cessation
- 1987-07-24 HU HU873407A patent/HU200458B/hu unknown
- 1987-07-24 EP EP87306570A patent/EP0254588B1/en not_active Expired - Lifetime
- 1987-07-24 DE DE8787306570T patent/DE3776018D1/de not_active Expired - Lifetime
- 1987-07-24 MX MX007489A patent/MX168756B/es unknown
- 1987-07-24 US US07/077,686 patent/US4808596A/en not_active Expired - Lifetime
-
1992
- 1992-02-11 GR GR920400203T patent/GR3003777T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU7562887A (en) | 1988-01-28 |
ES2038184T3 (es) | 1993-07-16 |
KR940002824B1 (ko) | 1994-04-04 |
AU598564B2 (en) | 1990-06-28 |
US4808596A (en) | 1989-02-28 |
HU200458B (en) | 1990-06-28 |
GR3003777T3 (ko) | 1993-03-16 |
JPH0643426B2 (ja) | 1994-06-08 |
JPS63146882A (ja) | 1988-06-18 |
EP0254588A1 (en) | 1988-01-27 |
ZA875151B (en) | 1988-01-21 |
DE3776018D1 (de) | 1992-02-27 |
CA1329204C (en) | 1994-05-03 |
EP0254588B1 (en) | 1992-01-15 |
AR245718A1 (es) | 1994-02-28 |
MX168756B (es) | 1993-06-07 |
HUT46000A (en) | 1988-09-28 |
ATE71626T1 (de) | 1992-02-15 |
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