KR850008278A - 니카르디핀 염산염의 주사용 제제의 제조방법 - Google Patents
니카르디핀 염산염의 주사용 제제의 제조방법 Download PDFInfo
- Publication number
- KR850008278A KR850008278A KR1019850003448A KR850003448A KR850008278A KR 850008278 A KR850008278 A KR 850008278A KR 1019850003448 A KR1019850003448 A KR 1019850003448A KR 850003448 A KR850003448 A KR 850003448A KR 850008278 A KR850008278 A KR 850008278A
- Authority
- KR
- South Korea
- Prior art keywords
- nicardipine hydrochloride
- preparation
- injectable preparations
- polyhydric alcohol
- nicardipine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (2)
- 니카드리핀 염산염과, 주사용 제제 총량에 대해 2내지 7W/V%의 다가 알콜을 물에 용해시키고, 용액의 pH를 2.5내지 5로 조정함을 특징으로 하는 니카르디핀 염산염의 주사용 제제를 제조하는 방법.
- 제1항에 있어서, 다가 알콜을 소르비틀, 만니틀, 크실리틀, 프로필렌 글리콜, 글리세롤 및 이노시틀로 이루어진 그룹중에서 선택하는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP102991 | 1984-05-22 | ||
JP10299/84 | 1984-05-22 | ||
JP59102991A JPS60246313A (ja) | 1984-05-22 | 1984-05-22 | 塩酸ニカルジピンの注射剤およびその製法 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR850008278A true KR850008278A (ko) | 1985-12-16 |
KR910003555B1 KR910003555B1 (ko) | 1991-06-05 |
Family
ID=14342164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019850003448A KR910003555B1 (ko) | 1984-05-22 | 1985-05-20 | 니카르디핀 염산염의 주사용 제제의 제조방법 |
Country Status (11)
Country | Link |
---|---|
US (1) | US4880823A (ko) |
EP (1) | EP0162705B1 (ko) |
JP (1) | JPS60246313A (ko) |
KR (1) | KR910003555B1 (ko) |
AT (1) | ATE63810T1 (ko) |
CA (1) | CA1240930A (ko) |
DE (1) | DE3582954D1 (ko) |
ES (1) | ES8700567A1 (ko) |
GR (1) | GR851230B (ko) |
MX (1) | MX9203588A (ko) |
PT (1) | PT80486B (ko) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8617482D0 (en) * | 1986-07-17 | 1986-08-28 | Geistlich Soehne Ag | Pharmaceutical composition |
US5210083A (en) * | 1986-07-17 | 1993-05-11 | Ed. Geistlich Sohne A.G. Fur Chemische Industrie | Pharmaceutical compositions |
JPH0696533B2 (ja) * | 1987-01-14 | 1994-11-30 | 北陸製薬株式会社 | キノロンカルボン酸の水性組成物 |
YU45837B (sh) * | 1988-01-18 | 1992-07-20 | LEK TOVARNA FARMACEVTSKIH IN KEMIČKIH IZDELKOV d.d. | Postopek za pripravo novega inkluzijskega kompleksa nikardipina oz. njegovega hidroklorida z beta-ciklodekstrinom |
GB2228412B (en) * | 1989-02-28 | 1993-04-14 | Syntex Inc | Nicardipine pharmaceutical composition for parenteral administration |
WO1998001138A1 (fr) * | 1996-07-04 | 1998-01-15 | Nippon Kayaku Kabushiki Kaisha | Injections de succinate sodique de methylprednisolone |
US20070112041A1 (en) * | 2005-11-16 | 2007-05-17 | Sun Pharmaceutical Industries Limited | Nicardipine injection composition |
JP2009534388A (ja) | 2006-04-18 | 2009-09-24 | イーケーアール セラピューティクス, インク. | 予備混合即時使用製薬製剤 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3720761A (en) * | 1968-10-14 | 1973-03-13 | W Hunter | Injectable radio-pharmaceutical scanning agent and preparation |
DE2935451A1 (de) * | 1979-09-01 | 1981-03-19 | Bayer Ag, 5090 Leverkusen | Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel |
DE3023495C2 (de) * | 1980-06-24 | 1982-04-08 | Kienzle Apparate Gmbh, 7730 Villingen-Schwenningen | Diagrammauswertegerät für die Unfalldiagrammauswertung von Fahrtschreiber-Diagrammen |
JPS57167967A (en) * | 1981-04-08 | 1982-10-16 | Yoshitomi Pharmaceut Ind Ltd | 1,4-dihydropyridine-3,5-dicarboxylic acid ester or its salt |
DE3205504C2 (de) * | 1982-02-16 | 1983-12-01 | Dolorgiet Gmbh & Co Kg, 5300 Bonn | Äußerlich anwendbares, Ibuprofen enthaltendes Arzneimittel |
JPS58172312A (ja) * | 1982-04-02 | 1983-10-11 | Toa Eiyou Kagaku Kogyo Kk | ニフエジピン外用剤 |
DE3212736A1 (de) * | 1982-04-06 | 1983-10-13 | Bayer Ag, 5090 Leverkusen | Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung |
JPS597163A (ja) * | 1982-07-02 | 1984-01-14 | Yamanouchi Pharmaceut Co Ltd | 抗動脈硬化剤 |
DE3307422A1 (de) * | 1983-03-03 | 1984-09-06 | Bayer Ag, 5090 Leverkusen | Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen |
DE3316510A1 (de) * | 1983-05-06 | 1984-11-08 | Bayer Ag | Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen |
JPS6016917A (ja) * | 1983-07-08 | 1985-01-28 | Yamanouchi Pharmaceut Co Ltd | 塩酸ニカルジピンまたはニフエジピンの軟膏剤 |
-
1984
- 1984-05-22 JP JP59102991A patent/JPS60246313A/ja active Granted
-
1985
- 1985-05-17 PT PT80486A patent/PT80486B/pt unknown
- 1985-05-20 GR GR851230A patent/GR851230B/el unknown
- 1985-05-20 KR KR1019850003448A patent/KR910003555B1/ko not_active IP Right Cessation
- 1985-05-21 ES ES543343A patent/ES8700567A1/es not_active Expired
- 1985-05-21 CA CA000481975A patent/CA1240930A/en not_active Expired
- 1985-05-21 AT AT85303588T patent/ATE63810T1/de not_active IP Right Cessation
- 1985-05-21 EP EP85303588A patent/EP0162705B1/en not_active Expired - Lifetime
- 1985-05-21 DE DE8585303588T patent/DE3582954D1/de not_active Expired - Lifetime
-
1989
- 1989-04-12 US US07/338,402 patent/US4880823A/en not_active Ceased
-
1992
- 1992-06-26 MX MX9203588A patent/MX9203588A/es active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ES543343A0 (es) | 1986-10-16 |
MX9203588A (es) | 1992-07-31 |
EP0162705A3 (en) | 1987-01-28 |
ES8700567A1 (es) | 1986-10-16 |
CA1240930A (en) | 1988-08-23 |
GR851230B (ko) | 1985-11-25 |
EP0162705B1 (en) | 1991-05-29 |
PT80486B (en) | 1986-12-12 |
JPS60246313A (ja) | 1985-12-06 |
PT80486A (en) | 1985-06-01 |
US4880823A (en) | 1989-11-14 |
DE3582954D1 (de) | 1991-07-04 |
KR910003555B1 (ko) | 1991-06-05 |
EP0162705A2 (en) | 1985-11-27 |
JPH0247964B2 (ko) | 1990-10-23 |
ATE63810T1 (de) | 1991-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 19990413 Year of fee payment: 14 |
|
EXPY | Expiration of term |