KR840002029A - 스태필로 키나아제를 산생하는 유전자를 함유하는 새로운 대장균 및 스태필로키나아제의 제조법 - Google Patents
스태필로 키나아제를 산생하는 유전자를 함유하는 새로운 대장균 및 스태필로키나아제의 제조법 Download PDFInfo
- Publication number
- KR840002029A KR840002029A KR1019820004582A KR820004582A KR840002029A KR 840002029 A KR840002029 A KR 840002029A KR 1019820004582 A KR1019820004582 A KR 1019820004582A KR 820004582 A KR820004582 A KR 820004582A KR 840002029 A KR840002029 A KR 840002029A
- Authority
- KR
- South Korea
- Prior art keywords
- staphylokinase
- escherichia coli
- preparation
- dna
- containing genes
- Prior art date
Links
- 101710145796 Staphylokinase Proteins 0.000 title claims 5
- 241000588724 Escherichia coli Species 0.000 title claims 3
- 108090000623 proteins and genes Proteins 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 claims 3
- 241000191940 Staphylococcus Species 0.000 claims 2
- 230000002068 genetic effect Effects 0.000 claims 2
- 241000191967 Staphylococcus aureus Species 0.000 claims 1
- 238000003306 harvesting Methods 0.000 claims 1
- 230000007774 longterm Effects 0.000 claims 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (2)
- 스태필로콕커스, 오오레우스의 용원(溶原) 파아지 DNA를 절달하여 얻은 스태필로키나아제 산생의 유전정보를 담당한 DNA를 전체 조직중의 일부로서 삽입하여 안정시킨 벡터를 도입하게 한 새로운 대장균.
- 스태필로콕커스·오오레우스의 용원파아지 DNA를 절단하여 얻은 스태필로키나아제 산생의 유전정보를 담당하는 DNA를 전체 조직중의 일부로서 삽입하여 안정시킨 벡터를 도입시킨 대장균을 배양하여 그 배양 균체에 축적한 스태필로키나아제를 채취하는 것을 특징으로 하는 스태필로키나아제의 제조법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56164064A JPS5867181A (ja) | 1981-10-16 | 1981-10-16 | スタフイロキナーゼ産生遺伝情報を担うdna断片組み換え体dnaおよびそれを導入した大腸菌 |
JP81-164064 | 1982-10-16 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR840002029A true KR840002029A (ko) | 1984-06-11 |
KR910001807B1 KR910001807B1 (ko) | 1991-03-26 |
Family
ID=15786090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR8204582A KR910001807B1 (ko) | 1981-10-16 | 1982-10-12 | 스태필로키나아제를 생산하는 유전자를 함유하는 새로운 대장균 및 스태필로키나아제의 제조법 |
Country Status (7)
Country | Link |
---|---|
US (1) | US4532211A (ko) |
EP (1) | EP0077664B1 (ko) |
JP (1) | JPS5867181A (ko) |
KR (1) | KR910001807B1 (ko) |
CA (1) | CA1206109A (ko) |
DE (1) | DE3280175D1 (ko) |
DK (1) | DK164001C (ko) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU561372B2 (en) * | 1983-10-10 | 1987-05-07 | Board Of Regents Of The University Of Oklahoma, The | Streptokinase-coding recombinant vectors |
US4764469A (en) * | 1984-03-02 | 1988-08-16 | Board Of Regents For The University Of Oklahoma | Streptokinase-coding recombinant vectors |
US5066589A (en) * | 1984-03-02 | 1991-11-19 | Board Of Regents Of The University Of Okla. | Streptokinase-coding recombinant vectors |
US5683909A (en) * | 1984-03-02 | 1997-11-04 | Van Den Bergh Foods Company, Division Of Conopco, Inc. | Plasmids replicatable in Bacillus subtilis, E. coli and lactic acid streptococcus bacteria |
DE3578852D1 (de) * | 1984-09-26 | 1990-08-30 | Lilly Co Eli | Verfahren zur expression und sekretion in bacillus. |
IT1176997B (it) * | 1984-10-17 | 1987-08-26 | Anic Spa | Procedimento per la produzione di proteasi neutra |
CA1339211C (en) * | 1988-04-14 | 1997-08-05 | Masashi Sakai | Plasminogen activator and thrombolytic agent |
WO1993013209A1 (de) * | 1991-12-30 | 1993-07-08 | Medac Gesellschaft für klinische Spezialpräparate mbH | Expression signalpeptid-freier staphilokinasen |
CN1035192C (zh) * | 1994-04-04 | 1997-06-18 | 上海医科大学 | 一种重组葡激酶的制备方法 |
US6383483B1 (en) | 1995-01-06 | 2002-05-07 | Désiré José Collen | Staphylokinase derivatives with cysteine substitutions |
US5951980A (en) * | 1995-01-06 | 1999-09-14 | Leuven Research & Development Vzw | Identification, production and use of new staphylokinase derivatives with reduced immunogenicity |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4366246A (en) * | 1977-11-08 | 1982-12-28 | Genentech, Inc. | Method for microbial polypeptide expression |
JPS54107589A (en) * | 1978-02-09 | 1979-08-23 | Ajinomoto Co Inc | Separation and purification of staphylokinase |
-
1981
- 1981-10-16 JP JP56164064A patent/JPS5867181A/ja active Granted
-
1982
- 1982-10-12 KR KR8204582A patent/KR910001807B1/ko active
- 1982-10-15 CA CA000413486A patent/CA1206109A/en not_active Expired
- 1982-10-15 US US06/434,503 patent/US4532211A/en not_active Expired - Lifetime
- 1982-10-15 DK DK460182A patent/DK164001C/da active
- 1982-10-15 DE DE8282305508T patent/DE3280175D1/de not_active Expired - Lifetime
- 1982-10-15 EP EP82305508A patent/EP0077664B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0077664A2 (en) | 1983-04-27 |
DK460182A (da) | 1983-04-17 |
EP0077664B1 (en) | 1990-05-16 |
KR910001807B1 (ko) | 1991-03-26 |
JPS5867181A (ja) | 1983-04-21 |
JPH0478276B2 (ko) | 1992-12-10 |
DK164001C (da) | 1992-09-21 |
US4532211A (en) | 1985-07-30 |
DK164001B (da) | 1992-04-27 |
DE3280175D1 (de) | 1990-06-21 |
CA1206109A (en) | 1986-06-17 |
EP0077664A3 (en) | 1984-05-02 |
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