KR20170085703A

KR20170085703A - Composition for anti-inflammatory and inhibiting comprising extracts derived from natural materials

Info

Publication number: KR20170085703A
Application number: KR1020160005162A
Authority: KR
Inventors: 함동곤; 홍민기
Original assignee: 울산과학대학교 산학협력단
Priority date: 2016-01-15
Filing date: 2016-01-15
Publication date: 2017-07-25

Abstract

The present invention relates to a composition for removing oral anti-inflammatory and deodorant from natural plant extracts containing an extract of Leaf faucet, Bleach extract, Gugija extract, Pine needles extract, Butterfly flower extract, menthol and EM as active ingredients, , And it was confirmed that the natural mint tea was used to enhance mild taste and natural menthol component. Thus, it can be used as oral cleanser, toothpaste, goggle or oral cosmetic product.

Description

TECHNICAL FIELD The present invention relates to a composition for removing oral anti-inflammatory and deodorant containing natural plant extract as an active ingredient,

The present invention relates to a composition for removing oral anti-inflammatory and deodorant from natural plant extracts containing an extract of Leaf faucet, White Bark extract, Gugija extract, Pine needles extract and Butterfly flower extract as an active ingredient.

It is known that periodontal disease and tooth decay associated with cold are caused by bacteria that grow collectively in the gum area. Therefore, the most important factor to prevent tooth decay and periodontal disease is to effectively remove the bacteria. However, there is a growing demand for periodic mouthwashes because toothbrushing alone makes it difficult to completely remove these bacteria.

Generally, bad breath is caused by the decomposition of proteins, food residues, etc. in saliva by microorganisms in the oral cavity, which are then decomposed by deacylation enzymes or amino enzymes to generate odor-inducing substances. In addition to volatile sulfides, volatile amine compounds such as triethylamine, aldehydes, fatty acids, and ammonia are the main ingredients that cause bad breath.

Background Art [0002] So far, compositions for oral use that show effects such as halitosis suppression, halitosis neutralization, and sterilization of microorganisms in the oral cavity have been disclosed in which oral compositions for increasing the content of specific flavor components such as mint and menthol, , Or a natural plant extract known to have a deodorizing effect such as a herbal extract and a green tea extract.

Oral cleansers sold on the market serve as disinfectants, and compositions containing triclosan, cetylpyridium chloride, and the like are used to inhibit the growth of anaerobic bacteria that cause bad breath. However, these compositions are used not only as anaerobic bacteria, In Salivarius K12, Salivarius MAT, and probiotics, there is a problem that the oral immunity is reduced and the balance is broken when used for a long period of time. The oral cleaning agent sold in the market has a high content of surfactant and synthetic antimicrobial agent, If you do not rinse your mouth properly after gaggle, the surfactant left in your mouth gives a strong stimulus to the inside of the mouth and dry the mucous membrane, which may cause the bad breath induction. have.

Korean Published Patent Application No. 2008-0107279 (published Dec. 10, 2008)

In order to solve the above problems, the present invention provides a method of treating dry mouth, which is harmless to the mouth and the human body and reduces dry feeling in the oral cavity by using extracts of natural plants such as faeces, white paper, And to provide an effective oral cleaning agent for improving periodontal disease.

The present invention provides a composition for the oral anti-inflammatory and deodorant removal from natural plant extracts containing an extract of Trichomoniasis, Bleach, Extract, Pine Needle, Butterfly, Menthol and E-M as active ingredients.

The composition comprises 3% by weight of a root extract, 1% by weight of a whiteness extract, 1% by weight of a pine needle extract, 25% by weight of a pine needle extract, 4% by weight of a butterfly flower extract, 40% % And residual water.

The composition may further comprise at least one of 0.04% by weight of grapefruit seed extract, 0.04% by weight of lemon essential, and 0.04% by weight of eucalyptus solution.

In addition, the present invention provides a method for producing a plant extract, which comprises the steps of: 3 wt% of a leaf extract, 1 wt% of a blank extract, 1 wt% of a pine extract, 25 wt% of a pine leaf extract, 4 wt% of a butterfly flower extract, 40 wt% (First step); In the first step, 0.04% by weight of grapefruit seed extract, 0.04% by weight of lemon essential, and 0.04% by weight of eucalyptus solution are further added and mixed (step 2); And mixing a residual amount of water to the aqueous solution mixed in the second step so as to make a composition of 100% by weight (third step).

According to the present invention, a composition for removing oral anti-inflammatory and deodorant from natural plant extracts containing an extract of Leaf faucet, Bleach extract, Gugija extract, Pine needles extract, Butterfly flower extract, Menthol and EM as active ingredients is a non-alcoholic product, I could not feel my dry feeling at all, and I could confirm that the refreshing taste was increased with mild taste and natural menthol ingredient by using natural lute tea.

FIG. 1 is a result of evaluating the cooling sensation, the residual sensation, the clear taste, and the degree of stimulation according to the change in the menthol content in the oral cleanser to which the extract of the tap root was added.

The present invention can provide a composition for removing oral anti-inflammatory and deodorant from natural plant extracts containing an extract of Trichomonium, Bleach, Extract, Pine Needle Extract, Butterfly Flower Extract, Menthol and E-M as active ingredients.

The extract may be extracted with a C1 to C4 alcohol, water or a mixed solvent thereof, more preferably a hot-water extract.

It contains more than 93% moisture, protein, carbohydrate, calcium, phosphorus, vitamin A, and C in a 1-year-old herb. The distinctive color of the branch is the color represented by the glycosides called nasinin (purple) and hyacinth (reddish brown), which are anthocyanin pigments, and it has the property of absorbing the fat and dissolving the wastes in the blood vessels and cleansing the blood.

In addition, branches and branches have scopoletin (Scopoletin) and Scoparone (Scoparone) contains ingredients with antispasmodic properties, these components show a gentle action is used for pain relief. Although the branch faucets have been used for stomatitis and dental caries, there is a lack of research on the products and manufacturing methods of natural mouth cleansers using the faucets.

The white paper is composed of antimicrobial action by pharmacological action, animal aging vascular exercise center, respiratory center, excitatory action of vagus nerve and spinal cord part, coronary artery blood flow increasing action, white wind wind (white spot wind) Disease: Chronic skin disease, erythema and papules caused by multiple layers of white scale powder on the surface of the skin due to pelvic pain) has been reported to be effective, and headache caused by influenza, nasal congestion, analgesic drugs to control runny nose, gastrointestinal disorder , Prenatal postpartum headache, dizziness, toothache, facial neuralgia, paralysis. It is also used for menstrual irregularities, when the blood is mixed in the stomach and stool, for headache due to sinusitis, for rejuvenation, for tame, for skin ulcers.

The goji-za has the appearance of tubular or sculptural shape, the outer surface is yellow, grayish brown, the inner side is gray, and the skin is easily scaly. It is used for sweating, seawater, asthma, hemorrhage, nosebleeds, bleeding, hyperglycemia, high blood pressure, neuralgia, headache, shoulder pain, muscle pain, back pain, weakness of the back and knee. The pharmacological action of the cardiovascular system, blood pressure lowering action, hypoglycemic action was reported.

Butterfly Flower The herb is a Thai herb plant called "Anchan", which is a traditional Thai herb, and has three colors of white, blue, and purple. Butterfly flowers are not only beautiful but also have an excellent effect on good hair quality in Thai traditional medicine, so that leaves, flowers, seeds and roots are used as herbs.

Anthocyanin, which contains a lot of butterflies flowers, has the effect of treating eye inflammation, improving eyesight, nourishing hair, and strengthening antioxidant and body immunity, so that it can be used as a raw material for cosmetics, hair products, Is used.

Effective micro-organisms (E-M), which is a beneficial microorganism, induces antioxidative action upon administration and inhibits the accumulation of human oxygen in the active oxygen causing aging.

The composition may be an oral cleanser, a toothpaste, a gauze, or an oral cosmetic.

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, the present invention will be described in detail with reference to the following examples. However, the following examples are intended to illustrate the contents of the present invention, but the scope of the present invention is not limited to the following examples. Embodiments of the present invention are provided to more fully describe the present invention to those skilled in the art.

< Example 1> Preparation of Oral Cleansing Agent Using Leaf Extract

1. Preparation of extract

1-1. White paper extract

82 g of white paper and 1,250 mL of water were added to a hot water bath and the mixture was stirred for 6 hours. The crude solution was collected and concentrated for 1 hour to prepare a 500 ml concentrate.

1-2. Eggplant extract

112 g of the cut faeces was added to 1,250 mL of water and boiled for 6 hours. The mixture was then concentrated for 1 hour to prepare a 500 mL concentrate.

1-3. Gugija extract

82 g of Gugija and 1,250 mL of water were added to a hot water bath, and the mixture was stirred for 6 hours and then concentrated for 1 hour to prepare a 500 ml concentrate.

1-4. Butterfly Flower Hub extract

4 g of Thai Anthancha (butterfly flower) was dissolved in 100 mL of water and used.

1-5. Pine leaf extract

One pine needle (Guangdong Pine needle) was dissolved in 1000 mL of water, and 8 g of menthol was dissolved in 100 mL of water.

1-6. Other additives

E-M stock solution was purchased from EM Green, 1 mL of E-M stock solution was dissolved in 1000 mL of water, and grapefruit seed extract, lemon essential oil and eucalyptus base were purchased from BMC Co., Ltd.

2. Oral cleanser manufacturing process

3 mL of the branch faeces extract, 1 mL of the white ground extract, 1 mL of the ginger extract, 25 mL of the pine needle extract, 25 mL of EM, 40 mL of menthol and 4 g of the butterfly flower herb were mixed with 0.04 g of lemon essential oil and 0.04 g of grapefruit seed extract g and eucalyptus (0.04 g) were added thereto to prepare a wax solution.

< Experimental Example 1> Confirmation rate of oral cleaning agent

1. Confirmation of addition rate of branch faucet extract

In order to confirm the taste and refreshing sensation according to the mixing ratio of the branch faucet extract, 1 to 15 mL of the branch faucet extract was added to 100 mL of the mouth cleaner prepared in Example 1, The sensation of cooling sensation, residue and taste of mouth cleaner were evaluated and the optimum amount of extract of faecal extract was confirmed.

As a result, it was confirmed that when the addition of 5 mL or more of the extract of the branch faucet was added as shown in Table 1, a slight taste was felt due to the unpleasant taste, while the evaluation of the mouth cleaner containing 3 mL of the branch faucet extract was the best.

Experimental group One Experimental group 2 Experimental group 3 Experimental group 4 Experimental group 5 Experimental group 6 Branch faucet
extract 5 mL 10 mL 15 mL 1 mL 3 mL 7 mL Refreshing feeling Prize medium medium Prize Prize medium Residual feeling Ha Prize Prize Ha Ha Ha A tasty taste Ha medium Prize Ha Ha medium Degree of stimulation radish radish radish U radish radish

2. menthol Confirmed change of cooling sensation according to content

The menthol content was changed to 20, 25, 30, 35, 40 and 45 mL per 100 mL of the oral cleaner prepared in Example 1 to cause oral irritation when the menthol was contained in an excessive amount, The amount of menthol added was evaluated by evaluating the cooling sensation, residual feeling, salty taste, and irritation degree of the oral cleanser.

As a result, as shown in Table 2 and FIG. 1, although oral mouthwash containing 40 mL of menthol was generally the best, there was a difference depending on the individual taste.

Experimental group One Experimental group 2 Experimental group 3 Experimental group 4 Experimental group 5 Experimental group 6 menthol 20 mL 25 mL 30 mL 35 mL 40 mL 45 mL Refreshing feeling Ha Ha medium medium Prize Prize Residual feeling Prize medium medium Ha Ha Ha A tasty taste Prize Prize medium medium Ha Ha Degree of stimulation Ha Ha Ha medium medium Prize

< Experimental Example 2> Sensory evaluation

The dryness of the oral cleanser prepared in Example 1 was compared with the dryness of the mouth cleanser sold in the market over time.

As a result, as shown in Table 3, the mouthwash product containing the extract of the branch faucet prepared in Example 1 was less non-alcoholic than the commercially available mouthwash that could induce more bad breath over time, , It was confirmed that the natural menthol ingredient was very effective because of its increased freshness.

Comparison of dryness over time after gaggling Elapsed time 5 minutes elapsed Ten minutes later 20 minutes elapsed 30 minutes past Commercial Oral Cleanser radish U U U Example 1
Oral cleanser radish radish radish radish

While the present invention has been particularly shown and described with reference to specific embodiments thereof, those skilled in the art will appreciate that such specific embodiments are merely preferred embodiments and that the scope of the present invention is not limited thereby. something to do. It is therefore intended that the scope of the invention be defined by the claims appended hereto and their equivalents.

Claims

A composition for removing intra-oral anti-inflammatory and deodorant from natural plant extracts containing an extract of Leaf faucet, white fly extract, Gujia extract, pine leaf extract, butterfly flower extract, menthol and E-M as active ingredients.

The composition according to claim 1, wherein the composition comprises 3% by weight of a root extract, 1% by weight of a whiteness extract, 1% by weight of a myrtle extract, 25% by weight of a pine needle extract, 4% %, EM of 25% by weight, and water of the remaining amount.

The composition of claim 1 or 2, wherein the composition further comprises at least one of 0.04% by weight of grapefruit seed extract, 0.04% by weight of lemon essential, and 0.04% by weight of eucalyptus solution.

[Claim 2] The composition according to claim 1, wherein the extract is extracted with C1 to C4 alcohol, water or a mixed solvent thereof.

The composition according to claim 1, wherein the composition is an oral cleanser, a toothpaste, a goggle or a cosmetic for oral cavity.

(Step 1) of adding 3% by weight of a leaf extract, 1% by weight of a whitened leaf extract, 1% by weight of a leaf extract, 25% by weight of a pine needle extract, 4% by weight of a butterfly flower extract, 40% by weight of menthol and 25% ;
In the first step, 0.04% by weight of grapefruit seed extract, 0.04% by weight of lemon essential, and 0.04% by weight of eucalyptus solution are further added and mixed (step 2); And
The method for preparing a composition for removing oral anti-inflammatory and deodorant according to claim 2, wherein the aqueous solution mixed in the second step is mixed with a residual amount of water to make a composition of 100% by weight (third step).