KR20170013047A

KR20170013047A - Cosmetic composition for improving skin elasticity, skin moisturizing, skin whitening and relieving atopy comprising herbal mixture extracts as an active ingredient and preparation method thereof

Info

Publication number: KR20170013047A
Application number: KR1020150105882A
Authority: KR
Inventors: 유상기
Original assignee: 유상기
Priority date: 2015-07-27
Filing date: 2015-07-27
Publication date: 2017-02-06

Abstract

The present invention relates to a cosmetic composition for improving skin elasticity, moisturizing skin, whitening skin, and alleviating atopy, and to a method for producing the same, wherein the cosmetic composition contains an herb medicine mixed extract as an active ingredient. More specifically, the cosmetic composition contains an alcohol extract as an active ingredient, and the alcohol extract is produced by combining hemp, Houttuynia cordata, linseed, green tea, Acorus gramineus Solander, Pleuropterus multiflorus TURCZ., and Perilla ocymoides at weight ratios of 1:0.9 to 1.1:0.4 to 0.6:0.4 to 0.6:0.4 to 0.6:0.9 to 1.1:0.4 to 0.6, and extracting the combined herbs by using alcohol as an extraction solvent. The cosmetic composition according to the present invention does not have skin toxicity, is safe to skin even when being used for a long time, and has excellent effects in improving skin elasticity, moisturizing skin, whitening skin, and alleviating atopy. Even when an additive for a cosmetic material is not used, the cosmetic composition smoothly infiltrate into skin. Accordingly, a more environmentally-friendly cosmetic product can be provided.

Description

TECHNICAL FIELD The present invention relates to a cosmetic composition for enhancing skin elasticity, skin moisturizing, skin whitening, and atopic dermatitis containing an extract of a herbal medicine as an active ingredient and a method for producing the same, and a method for producing the cosmetic composition comprising the skin moisturizing, skin whitening and relieving active ingredient and preparation method thereof}

The present invention relates to a cosmetic composition for enhancing skin elasticity, skin moisturizing, skin whitening and atopic dermatitis containing an extract of a herbal medicine as an active ingredient and a method for preparing the same, more specifically, And lollipops are mixed in a weight ratio of 1: 0.9 to 1.1: 0.4 to 0.6: 0.4 to 0.6: 0.4 to 0.6: 0.9 to 1.1: 0.4 to 0.6 to prepare an alcohol extract as an effective solvent Skin moisturizing, skin whitening, and atopic dermatitis, and a method for producing the same.

The skin consists of keratin, epidermis, dermis, and subcutaneous tissue, and functions to protect the human body from external factors or physical and chemical stimuli from the environment. The outer skin (Epidermis) is functionally divided into the stratum corneum, the transparent layer, the granular layer, and the basal layer from the outside to the inside. The dermis in the inner part is dense connective tissue and the hypodermis inside the dermis It serves to fix the skin to the internal organs. Among them, epidermis is the thinnest layer among the three skin structures, and it is a function to moisturize and protect the skin, and research on skin beauty has been actively carried out.

It has been reported that the skin layer of the epidermis must have an essential moisture content of 10% or more, and the thickness of the stratum corneum varies depending on the content.

The cells that make up this stratum corneum have a high concentration of Natural Moisturizing Factor (NMF), which is a water-soluble component, which helps the skin to maintain flexibility and maintain proper moisture. For example, The material is not only water-soluble, but also effectively combines with moisture to inhibit moisture from drying out of the skin. However, due to various causes such as age, sex, concrete area, continuous stimulation of the environment, and external stimuli such as increased stress, the moisture of the stratum corneum is decreased and the skin becomes dry, the surface becomes rough, The need for skin moisturizers is increasing. The major cause of skin aging is known to be influenced by various factors such as the content of various polysaccharides in the skin and the immune action ability to the external environment. One of the major influences is skin moisture content have.

Conventionally, a method of increasing water retention has been widely used by using a humectant having a property of absorbing moisture as a humectant and an occlusive moisturizer preventing evaporation of water. In addition, the formulations containing the lamellar liquid crystals, which have been undergoing much research until recently, are known to have excellent moisture retention due to their similar merits to the keratinous structures of the skin, but they can be manufactured only in a specific composition of the raw materials and thus have problems in universal use.

In the cosmetics industry, technologies featuring skin moisturization are being published through numerous papers and patents, and are being industrialized in a wide variety of products. Generally, a moisturizing function using a natural extract is applied to skin moisturizing cosmetic materials such as cucumber extract, carrot extract, green tea extract, safflower seed extract, marchia extract, ginkgo leaf extract, Cream, essence, packy, etc. are widely available as a product.

On the other hand, it contains Opunntia ficus indica extract, red ginseng extract, Lagerstroemia indica linne extract, Rubus Idaeus (Rapsberry) Fruit extract and Crataegus cuneata fruit extract. (Korean Patent No. 930,873) which can improve skin wrinkles, improve skin elasticity, and enhance skin moisturization, a patent for a composition for external application for skin (Korean Patent No. 930,873), a ginseng or red ginseng- (Korean Registered Patent No. 1,503,123), a herbal medicine extracted from a mixture of a composition for preventing skin aging or improving wrinkles (Korean Patent No. 1,503,123), a safflower, a safflower, a milky white, a chrysanthemum, Patent for cosmetic composition for antioxidant, skin moisturizing, whitening and anti-aging of skin based on extract Patent No. 1,056,756), but there is a problem in that the process of producing the extract or the process of separating the active ingredient is complicated, and the effect of preventing skin aging and wrinkling is insignificant.

Therefore, in recent years, there has been a growing interest in cosmetics using natural materials, and in order to develop safer and more effective raw materials for skin aging prevention derived from natural products, It is urgently required to develop cosmetics containing them.

Korean Registered Patent No. 930,873 (Registered on December 2, 2009) Korean Registered Patent No. 1,503,123 (registered on March 10, 2015) Korean Registered Patent No. 1,056,756 (registered on August 8, 2011)

The present invention is to provide a cosmetic composition containing an extract of a herbal medicine excellent in skin elasticity, skin moisturizing, skin whitening and atopic relief, without skin toxicity and long-term use, and a method for producing the same.

The present invention relates to a cosmetic composition which comprises (a) a mixture of (a) hemp, obovate, flaxseed, green tea, Adding alcohol to obtain an alcoholic extract, and aging the alcoholic extract; (b) heating the obtained alcohol extract to volatilize and remove the alcohol component, thereby solving the above problems by providing a cosmetic composition for skin elasticity enhancement, skin moisturizing, skin whitening, and atopic dermatitis.

In one embodiment of the present invention, step (a) further comprises an extract of at least one herbal medicine selected from the group consisting of ginseng, lettuce, brown rice, barley, genus, sorghum, flaxseed and ginger, In a weight ratio of 0.4 to 0.6 by weight. That is, when the ginseng is further included alone, it is included in a weight ratio of ginseng: 0.4 to 0.6. In addition, when the ginseng is further contained, the weight ratio of ginseng to ginseng is 0.4 to 0.6: 0.4 to 0.6.

The present invention also relates to a process for the production of a medicament for the prevention and / or treatment of cancer, comprising the step of blending cedar, cordierite, flaxseed, green tea, The present invention solves the above problems by providing a cosmetic composition for promoting skin elasticity, skin moisturizing, skin whitening and atopic dermatitis containing an alcohol extract extracted as an alcohol as an active ingredient.

In one embodiment of the present invention, the composition further comprises an extract of at least one herbal medicine selected from the group consisting of ginseng, lemongrass, brown rice, bovine, perilla, sorghum, flaxseed and ginger, 0.4 to 0.6. That is, when the ginseng is further included alone, it is included in a weight ratio of ginseng: 0.4 to 0.6. In addition, when the ginseng is further contained, the weight ratio of ginseng to ginseng is 0.4 to 0.6: 0.4 to 0.6.

The cosmetic composition according to the present invention is free from skin toxicity and is safe to the skin even when used for a long time, and has excellent skin elasticity, skin moisturizing, skin whitening and atopic dermatolytic effect and permeates well to the skin without using cosmetic additives. There is an advantage that cosmetics can be provided.

The present invention relates to a cosmetic composition which comprises (a) a mixture of (a) hemp, obovate, flaxseed, green tea, Adding alcohol to obtain an alcoholic extract, and aging the alcoholic extract; (b) heating the obtained alcohol extract to volatilize and remove the alcohol component. The present invention also relates to a method for producing a cosmetic composition for skin whitening, skin moisturizing, skin whitening, and atopic dermatitis.

In one embodiment of the present invention, in step (a), red ginseng or ginseng may be used, and more specifically, red ginseng can be used. In step (a), it is preferable to use a method that is regulated as sewage.

In one aspect of the present invention, the alcohol refers to alcohol.

In one embodiment of the present invention, at the time of aging, the fermented milk is aged at least 30 days, at least 40 days, at least 50 days, at least 60 days, at least 70 days, at least 80 days, at least 90 days, at least 100 days, at least 110 days, . When aged for 30 days or more, the toxic component of the herbal medicine itself is neutralized, and the content of the active ingredient is increased, so that the effect can be further enhanced. Most preferably 100 days or more.

The present invention also relates to a process for the production of a medicament for the prevention and / or treatment of cancer, comprising the step of blending cedar, cordierite, flaxseed, green tea, Skin moisturizing, skin whitening, and atopic dermatitis, which comprises an alcohol extract extracted with alcohol as an extraction solvent as an active ingredient.

In one embodiment of the present invention, red ginseng or ginseng may be used, and more specifically, red ginseng can be used. In addition, it is preferable to use a lawyer for sewage.

In one aspect of the present invention, the alcohol refers to alcohol.

In one embodiment of the present invention, the alcohol extract is preferably aged. It is preferable to aged at least 30 days, at least 40 days, at least 50 days, at least 60 days, at least 70 days, at least 80 days, at least 90 days, at least 100 days, at least 110 days and at least 120 days. When aged for 30 days or more, the toxic component of the herbal medicine itself is neutralized, and the content of the active ingredient is increased, so that the effect can be further enhanced. Most preferably 100 days or more.

In one embodiment of the present invention, the cosmetic composition can be used twice in the morning and evening twice a day. It is wiped with water before the self-evening, then sprayed on the necessary parts such as the face and lightly massage, . You can feel the skin elasticity when you wake up in the morning if you lightly massage with usual lotion.

In one aspect of the present invention, the formulations are not particularly limited and may be formulated into skins, lotions, essences, creams, packs, masks, etc. in the cosmetics range.

The present invention will be described in more detail with reference to the following examples and experimental examples. However, the following examples and experimental examples are provided to aid understanding of the present invention, and the scope of the present invention is not limited by these examples and experimental examples in any sense.

Examples. Preparation of cosmetic composition

The compositions of the present invention (Examples) and Comparative Examples were prepared with the compositions shown in Table 1 below. The amount of each herb medicine used is g units. A more detailed description is as follows:

The mixture was added to 5 liters of alcohol (flaxseed) with the composition shown in Table 1 and aged for 100 days. Thereafter, the solution was filtered, and the filtrate was heated to volatilize the alcohol component.

Red ginseng Sophora Flaxseed green tea Seokchangpo Sewage Lobular leaf figwort owner Brown rice Barb Slang Sorghum Flaxseed ginger Room 1 10 10 5 5 5 10 5 5 5 5 5 5 5 5 5 2 10 10 5 5 5 10 5 - 5 5 5 5 5 5 5 3 10 10 5 5 5 10 5 5 - 5 5 5 5 5 5 4 10 10 5 5 5 10 5 5 5 - 5 5 5 5 5 5 10 10 5 5 5 10 5 5 5 5 - 5 5 5 5 6 10 10 5 5 5 10 5 5 5 5 5 - 5 5 5 7 10 10 5 5 5 10 5 5 5 5 5 5 - 5 5 8 10 10 5 5 5 10 5 5 5 5 5 5 5 - 5 9 10 10 5 5 5 10 5 5 5 5 5 5 5 5 - Rain 1 - 10 5 5 5 10 5 5 5 5 5 5 5 5 5 2 10 - 5 5 5 10 5 5 5 5 5 5 5 5 5 3 10 10 - 5 5 10 5 5 5 5 5 5 5 5 5 4 10 10 5 - 5 10 5 5 5 5 5 5 5 5 5 5 10 10 5 5 - 10 5 5 5 5 5 5 5 5 5 6 10 10 5 5 5 - 5 5 5 5 5 5 5 5 5 7 10 10 5 5 5 10 - 5 5 5 5 5 5 5 5

(Examples 1 to 9 show Examples 1 to 9, and ratios 1 to 7 show Comparative Examples 1 to 7).

EXPERIMENTAL EXAMPLE 1 Effect of promoting elastin production

Human fibroblasts were treated with soybean extract to determine the inhibitory effect of elastase activity. The experimental method is as follows. Human fibroblasts were placed in a culture flask and cultured until they were about 70-80% grown. After the extracts of Examples 1 to 3 and Comparative Examples 1 to 7 were treated for 1 day, the cell culture medium was collected and the degree of elastin production was measured using a commercially available elastin measuring instrument (Reference 1). That is, the activity of elastase was measured using the absorbance of the change in color caused by the decomposition of NA by using Suc- (Ala) 3NA which is a substrate of elastase. At this time, the extracts of Comparative Examples 1 to 7 were used as a control group. The experimental results are shown in Table 2.

Test sample Active inhibition (%) Example 1 32 Example 2 31 Example 3 30 Comparative Example 1 15 Comparative Example 2 17 Comparative Example 3 18 Comparative Example 4 19 Comparative Example 5 15 Comparative Example 6 17 Comparative Example 7 18

Experimental Example 2: Promoting collagen production

Human fibroblasts were treated with the extract of Example and Comparative Example to measure the inhibitory effect on collagenase activity. The experimental method is as follows. Human fibroblasts were placed in a culture flask and cultured until they were about 70-80% grown. After the extracts of Examples 1 to 3 and the extracts of Comparative Examples 1 to 7 were treated for 1 day, the cell culture medium was collected and the degree of collagen production was measured using a commercially available apparatus for measuring collagenase activity (Reference 2 ). Namely, MMP-1 (Matrix Metalloproteinase-1) derived from human was quantified using an antibody against collagenase. At this time, Comparative Examples 1 to 7 were used as a control group. The experimental results are shown in Table 3.

Test sample Active inhibition (%) Example 1 27 Example 2 27 Example 3 26 Comparative Example 1 12 Comparative Example 2 14 Comparative Example 3 15 Comparative Example 4 15 Comparative Example 5 12 Comparative Example 6 11 Comparative Example 7 13

Experimental Example 3. Moisturizing effect

Skin moisturizing effect tests were conducted on the extracts of Example 1 and Comparative Example 1. MY-808S Moisture Checker (Scalar, Japan) was used for the skin moisturizing effect and clinical examination was performed using the inside of the forearm. In the method of measuring the moisture resistance, the skin moisturizing power before application was checked including the control group, and the skin moisturizing power after 1 hour, 2 hours, 3 hours, and 4 hours after each sample was applied at 0.25 g / cm ² was measured. The skin moisturizing ability was very sensitive to temperature and humidity, so it was conducted in a constant temperature and humidity room where the temperature was controlled at 20 ° C and 60% humidity. The subjects were tested on 5 male subjects and 40 male subjects. The experiment was conducted three times and averaged. Experimental results showed that the skin moisturizing effect was increased to about 36.5% after skin application with 25.4% of skin moisturizing power before application of the extract of Example 1, and skin moisturizing effect over time was examined. As a result, skin moisturizing effect after 4 hours The results of this study are as follows. On the other hand, the moisturizing effect of Comparative Example 1 was lowered to 28.5% after 25.6% of the skin was applied.

EXPERIMENTAL EXAMPLE 4 Effect of Atopy Reduction

The extracts of Examples 1 to 3 and Comparative Examples 1 to 7 were tested for anti-atopic effect. The atopic lesions of 2 patients with atopic symptoms and 3 patients of 20 patients were divided into 5 areas, and the extracts of Examples 1 to 3 and Comparative Examples 1 to 7 were applied twice in morning and evening, respectively. After one week, the degree of rash and the presence of itching were surveyed. The results are shown in the following table. (No oscillation: 5 points, weak oscillation: 4 points, no change in oscillation: 3 points, rash slightly deeply burdened: 2 points, severe rash: 1 point / no itching: 5 points, itching weakness: 4 points, No: 3 points, itching slightly worse: 2 points, itching is much worse: 1 point)

Test sample rash Itching Example 1 4.9 4.5 Example 2 4.8 4.4 Example 3 4.8 4.3 Comparative Example 1 3.2 3.0 Comparative Example 2 3.3 2.8 Comparative Example 3 3.1 2.9 Comparative Example 4 3.0 3.1 Comparative Example 5 2.9 3.0 Comparative Example 6 3.2 3.1 Comparative Example 7 2.9 2.8

As a result of the experiment, when the extracts of Examples 1 to 3 were applied to atopic skin, the rash was almost eliminated or disappearing, and the itching was greatly alleviated. On the other hand, in the case of Comparative Examples 1 to 7, the rash did not disappear or the itching persisted, and in some patients, the symptoms slightly deteriorated.

<References list>

1. Biochemical Medicine 11: 350-357, 1974 'The synthesis and analytical use of a highly sensitive and covenient substrate of elastase' and J. Invest Dermatol 86: 63-68, 1986 'Elastase and neutral cathepsin production by human fibroblasts effect culture conditions on synthesis and secretion

2. Anal Biochem 116 (1): 172-7, 1987 An assay for collagenase activity using enzyme-linked immunosorbent assay for mammalian collagenase

Claims

(a) A composition comprising (a) bamboo grass, bamboo shoot, flaxseed, green tea, silkworm, sachet and straw ladle in a weight ratio of 1: 0.9 to 1.1: 0.4 to 0.6: 0.4 to 0.6: 0.4 to 0.6: 0.9 to 1.1: 0.4 to 0.6, Adding alcohol to obtain an alcoholic extract, and then aging the alcoholic extract;
(b) volatilizing and removing the alcohol component by heating the obtained alcohol extract.
Skin elasticity, skin moisturization, skin whitening, and atopic dermatitis.

The method according to claim 1,
The method according to any one of claims 1 to 3, wherein the step (a) further comprises an extract of at least one herbal medicine selected from the group consisting of ginseng, lemon, brown rice, Wherein the cosmetic composition comprises at least one kind of cosmetics, at least one kind of cosmetics,

The composition of the present invention is prepared by blending the green algae, green algae, flaxseed, flaxseed, green tea, silkworm, sachet and straw liquor at a weight ratio of 1: 0.9-1.1: 0.4-0.6: 0.4-0.6: 0.4-0.6: 0.9-1.1: 0.4-0.6, A cosmetic composition for enhancing skin elasticity, skin moisturizing, skin whitening and atopic dermatitis containing an alcohol extract extracted as a solvent as an active ingredient.

The method of claim 3,
Characterized in that it further comprises an extract of at least one herbal medicine selected from the group consisting of ginseng, ginseng, brown rice, barley, genus, sorghum, flaxseed and ginger, each herbal medicine being contained in a weight ratio of 0.4 to 0.6 , Skin elasticity enhancement, skin moisturization, skin whitening, and atopic dermatitis.