KR20160130149A - Automatic Cytology Preparing System using a container for picking free medical treatment included pipet - Google Patents

Automatic Cytology Preparing System using a container for picking free medical treatment included pipet Download PDF

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Publication number
KR20160130149A
KR20160130149A KR1020160029251A KR20160029251A KR20160130149A KR 20160130149 A KR20160130149 A KR 20160130149A KR 1020160029251 A KR1020160029251 A KR 1020160029251A KR 20160029251 A KR20160029251 A KR 20160029251A KR 20160130149 A KR20160130149 A KR 20160130149A
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South Korea
Prior art keywords
block
container
coupled
filter
slide
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KR1020160029251A
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Korean (ko)
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KR101685459B1 (en
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이은혜
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이은혜
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/24—Suction devices
    • G01N2001/247—Syringes

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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hydrology & Water Resources (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The present invention relates to an automatic laminating apparatus using a sample vessel including a pipette which can perform smear processing more quickly by omitting a structure for separating and coupling a pipette for sucking and discharging cells from a container and simplifying the structure of the apparatus will be.

Description

Technical Field [0001] The present invention relates to an automatic lapping apparatus using a sample container including a pipette,

The present invention relates to an automatic laminating apparatus using a sample container including a pipette capable of automatically carrying out a series of smearing processes of collecting cells from a solution container containing cells detected by a patient and smearing them on a slide, The present invention relates to an automatic laminating apparatus using a sample vessel including a pipette which can perform smear processing more quickly by omitting a structure for separating and coupling a pipette for sucking and discharging cells from a container and simplifying the structure of the apparatus will be.

An automatic cell smear processing apparatus for inspection invented by the present inventor is disclosed in Korean Patent Application No. 10-2015-0021534 and in Fig.

This smearing apparatus comprises a tray stacking table 30 which is supported on one side of a main frame 101 and on which a tray 33 in which a first container 40 and a plurality of tips 50 are stacked; A second container mounting table 70 provided adjacent to the tray mounting table 30 and having a second container 60 stacked thereon; A slide magazine 80 provided adjacent to the second container mount 70 and having slides stacked thereon; A tray elevator 90 for taking out one tray from the tray stacker 30 and positioning the taken-out tray at a predetermined height; And a suction hose for supplying a suction force to the suction rods 111. The suction rods 111 are attached to the tips 50 of the tips 50, And a second position in which the tip (50) enters the first container (40) and sucks the solution with the cells. The suction rods (111 A first X-Y robot 110 for moving the first X-Y robot 110; The second container 60, which is provided on the movement path of the first X-Y robot 110 and receives test cells and solution solution discharged from the tip 50, is seated, A second container seating part 120 capable of reciprocating and elevating, having a discharge port 121 for discharging the solution solution from the second container seating part 120; Separating means for separating the tip (50) from the suction rod (111) after discharging the test cell and solution solution from the tip (50) to the second container (60); And a first conveying chuck (131) holding the second container (60) from the second container mounting table (70) to seat the second container on the second container placing table (120) A second X-Y robot 130 that reciprocates the chuck 131 between the second container mount 70 and the second container mount 120; A through-hole 141 provided on the movement path of the second container seating base 120 and through which a part of the second container 60 enters from the bottom, and a slide seating base 140; Detaching means for detaching the second container (60) from the second container seating base (120); And a plurality of slide conveying chucks (151) for placing a plurality of slides taken out from the slide magazine (80) on the slide seating stand (140), wherein each slide conveying chuck A 3X-Y robot 150; A take-out means for taking out the slide from the slide magazine (80); A second feeder (161) for feeding a slide, in which a part of the second container (60) is inserted into the through hole (141), into the slide holder (210) of the dyeing part, And a fourth X-Y robot 160 having a second X-Y robot.

In the above-described smearing apparatus, a hollow tip (50) is inserted into a first container (40) containing test cells and solution solution to inhale cells and solution solution, and the inhaled cells and solution solution are introduced into a second It is advantageous in that it is dispensed only in the container 60 to discharge only the solution solution, then the cells filtered by the filter are applied to the slide, and then the slide is attached to the dyeing holder 210.

However, in the above-described smearing apparatus, a separate first X-Y robot 110 for moving the tip 50 from the first container 40 to the second container 60 is required, In addition, there is a problem that the structure of the equipment becomes complicated.

Korean Patent No. 10-0385169

Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made in order to solve the above-mentioned problems, and it is an object of the present invention to provide a filter and a fixture by sucking cells and a solution solution from a container containing cells and solution solution, And to provide an automatic smearing apparatus using a sample container including a pipette having an improved structure so that a series of steps of smearing cells remaining on a filter fixture onto a slide can be performed more quickly than before.

According to an aspect of the present invention for achieving the above object, there is provided a container comprising a container body accommodating solution solution and collected cells, the container body having a bottom opened, and a cap member detachably coupled to the container body, Wow; A bottom plate formed to protrude upward at a central portion of the pipette to be inserted into the through hole; an upper joint extending upward from an edge of the bottom plate and detachably coupled to the cap member; A connecting member having a first flange formed on an outer periphery thereof; A body having an intermediate plate having a tubular shape with a suction hole formed therein and having an upper portion detachably coupled to the lower engaging portion and a vacuum inhaler coupled to a lower portion of the intermediate plate and a second flange formed on an outer periphery of the body, And a filter fixture having a membrane filter attached to an upper end of the body, the pipette including a pipette for extracting cells from the container assembly and smearing the slides, the automatic lashing apparatus comprising:

A lower fixed block;

A plurality of first vertical bars disposed on the upper side of the lower fixed block and spaced apart from each other by a predetermined distance, a first through hole penetrating the upper and lower fixing blocks is vertically formed, An upper fixing block having a first slit into which the flange slides and is formed;

A top plate spaced apart from the upper fixing block by a plurality of second vertical bars;

A second through hole to which the container is coupled is formed and a seating step is formed on the inner circumference of the second through hole to support an end of the container, A first lifting block that is lifted and lowered so that a lower end of the container is detached;

A second slit is formed in the inner periphery of the seating groove in which the second flange slides, a suction hole is formed in a bottom surface of the seating groove, A second lifting block slidably coupled to the vertical bar so as to be lifted and lowered so that the filter fixing body is attached to and detached from a lower portion of the connecting body coupled to the upper fixing block;

The first elevating block is lowered and the second elevating block is elevated so that the cell and solution solution in the container is sucked into the filter fixture in a state where the container, A suction pipe connected to provide a suction pressure;

And a slide block having a third slit coupled to the lower surface of the slide so that the lower surface of the slit is opened and moving the slide to an upper side of the filter fixing body when the second lift block is lowered,

And the filtered cells on the upper surface of the filter fixing body are smudged on the lower surface of the slide while the second lifting block is lifted.

The smearing apparatus of the present invention is further characterized by a take-out means for taking out the connector and the filter fixture from the upper fixed block and the second lift block after the cells are smudged.

Further, the takeout means includes a pusher block having a pusher that enters the seating groove and reciprocates,

And a second horizontal rod having the pusher block slidably coupled thereto,

The pusher block is moved in a state that the second lifting block is lifted up and the connector and the filter fixing body are engaged and the pusher is advanced into the mounting recess, so that the pusher moves the coupled body and the filter fixing body to the upper fixing And the second lift block is pushed out of the block and the second lift block.

Since the pipette 54 of the present invention has a structure in which the pipette 54 is formed integrally with the connecting body 50, the structure is simplified and the smear time is shortened as compared with a conventional smelting apparatus using a pipette.

Figs. 1 to 4 are views for explaining a selection name smearing apparatus by the inventor of the present invention,
FIGS. 5 to 7 are views showing a container assembly applied to the smearing apparatus of the present invention, which is a schematic view for explaining a cell smearing process,
8 is a schematic view showing a state in which cells are laid on a slide,
FIG. 9A is a perspective view showing a container assembly applied to an inventive smearing apparatus, FIG.
FIG. 9B is an exploded perspective view of FIG. 9A,
FIG. 9C is a perspective view of the assembly of FIG.
10 is a perspective view of the smearing apparatus of the present invention,
11 is a plan view of Fig. 10,
FIG. 12 is a rear perspective view of FIG. 10,
Fig. 13 is an exploded perspective view of the main assembly of the apparatus to which the container assembly is coupled,
14 is a schematic sectional view for explaining the operation of the smearing apparatus of the present invention,
Figs. 15A to 15C are explanatory views for explaining the operation of the smearing apparatus of the present invention.

A sample container assembly having a pipette applied to the smearing apparatus of the embodiment of the present invention is configured as follows.

5, 6, and 9, it includes a container 100 in which the solution solution and the collected cells are accommodated, a linking member 50 that forms a path for movement of the solution solution in the container 100, , And a filter fixture (60) for separating the solution from the solution transferred through the connector (50).

A cap member 120 detachably coupled to the container body 110 to open and close the opening and having a through hole 121 at the center thereof; And a flexible elastic plate 140 coupled to the through hole 121.

A filter member 130 for filtering the suspended solids in the solution solution is coupled to the cap member 120.

The resilient plate 140 is formed of a material such as silicon and has a slender portion 140a thinner than the periphery at the center thereof to form an entry groove 141 into which the tip of the pipette 54 enters.

The elastic plate 140 is fixed to the cap member 120 by a paper sticker 150 having an adhesive on one side thereof. The sticker 150 prevents contamination of the elastic plate 140 and removes the sticker 150 at the time of use.

The connecting body 50 includes a bottom plate 53 formed by projecting a molten metal pipe (pipette) 54 passing through the elastic plate 140 and entering the inside of the container 100, An upper engaging portion 51 extending upward from an edge of the plate 53 and detachably coupled to the cap member 120 and a lower engaging portion 52 extending downward from an edge of the bottom plate 53, And a first flange 56 formed on the outer periphery.

The connector 50 allows the solution solution and the cells in the container 100 to be guided to the lower engaging part 52 side via the pipette 54.

A guide 55 is formed on the lower surface of the bottom plate 53 to guide the upper and lower light guides so that the cells guided by the pipette 54 are guided to the center of the membrane filter 63.

The filter fixing body 60 is cylindrical and has an intermediate plate 61 having a suction hole 61a formed at an intermediate portion thereof and an upper end detachably coupled to the lower coupling portion 52, A membrane filter 63 attached to the upper end of the body 65 and a second flange 66 formed on the outer circumference.

A cushion body 64 for passing the solution solution and supporting the membrane filter 63 is provided between the membrane filter 63 and the intermediate plate 61.

On the other hand, a packing 125 of silicone or rubber is attached to the outer circumferential surface of the cap member 120 so that airtightness is maintained when the cap member 120 and the upper engaging portion 51 are coupled, 400 can be precisely controlled.

A method of smearing cells from a sample container assembly having the above-described configuration is as follows.

First, the solution solution and the cells are received in the container body 110 and the cap member 120 is coupled. Then, the container 100 is inverted as shown in FIG. 5, so that the cap member 120 is positioned below.

The solution solution and the cells C are gathered at the lower part of the cap member 120 while the suspended matters of large particles are filtered through the filter member 130.

6, the container body 110 and the connecting body 50 are coupled to the filter fixing body 60 and the vacuum suction unit 400 is attached to the coupling portion 62 of the filter fixing body 60 Respectively.

At this time, the thin portion 140a of the elastic plate 140 is pierced, and the tip of the pipette 54 enters the container body 110.

The solution solution and the cells in the container 100 are introduced into the lower engaging portion 52 of the connecting body 50 through the pipette 54 by the suction force of the vacuum inhaler 400, The solution is discharged through the suction hole 61a of the intermediate plate 61 and the cells are filtered on the upper surface of the membrane filter 63. [

At this time, the cells are concentrated by the guide 55 in the central portion of the membrane filter 63 as shown in FIG. 8, so that the cells overlap to form a circle.

In this case, even if the center portion of the cushion body 64 and the membrane filter 63 is bent concave downward as the vacuum suction force is transmitted through the vacuum inhaler 400, the adhesion of the specimen cell to the slide 750 Can be improved.

After the filter fixture 60 is separated, sample cells are attached to the surface of the slide 750 by contacting the slide filter 750 with the membrane filter 63 as shown in Fig.

The cushion body 64 provides a cushion when the membrane filter 63 contacts the slide 750 to allow the cell C to be readily transferred to and attached to the slide 750, Thereby preventing the cell (C) from being denatured by the contact pressure.

These specimen cells are adhered to the surface of the slide 750 in the form of a circular cell circle, which has an advantage of improving cell analysis efficiency.

The apparatus for smearing cells from a sample container in which a pipette having the above-described structure is formed is constituted as follows.

10 to 14, the lower fixing block 200 is fixed to the upper portion of the base 1 by a plurality of support rods 2.

An upper fixing block 300 is fixed to the upper side of the lower fixing block 200 by being supported by a plurality of first vertical bars 310.

The upper fixing block 300 is formed with a first through hole 301 penetrating vertically and a first flange 56 of the connecting body 50 slides on an inner circumferential edge of the first through hole 301, So that the first slit 302 is formed.

The top plate 400 is disposed by a plurality of second vertical rods 410 spaced apart from the upper fixed block 300 and the first vertical block 410 is vertically Respectively.

The first through-hole block 501 is formed with a second through-hole 501 to which the container 100 is coupled, and an end of the container 100 is connected to the inner circumference of the second through- Is formed.

The container 100 is coupled to or separated from the connecting body 50 coupled to the upper fixing block 300 when the first elevating block 500 coupled to the container 100 is lifted or lowered.

A second vertical block 600 coupled to the filter fixing body 60 is slidably coupled to the first vertical block 310 so that when the second vertical block 600 is lifted and lowered, The filter fixing body 60 is coupled to or separated from the lower portion of the coupling body 50 coupled to the filter fixing body 300.

The second lift block 600 is formed with a seating groove 601 on which the filter fixing body 60 is seated and the second flange 66 is slidably inserted into the inner circumference of the seating groove 601 And a suction hole 603 is formed in the bottom surface of the seating groove 601 to connect the suction pipe 610 to the second slit 602.

 The first elevating block 500 is lowered and the second elevating block 600 is elevated so that the vessel 100, the connecting body 50 and the filter fixing body 60 The suction pipe 610 is provided with a suction pressure by a vacuum pump (not shown) so as to suck the solution of cells and solution in the container 100 toward the filter fixing body 60 in a state where the suction pipe 610 is coupled. At this time, only the solution solution is discharged through the suction pipe 610 and the cell C remains in the membrane filter 63.

The lower fixed block 200 is provided with a first horizontal rod 710 and a slide block 700 to which the slide 750 is coupled is reciprocally movable.

The slide block 700 moves the slide 750 to the upper side of the filter fixing body 60 when the second lift block 600 coupled to the filter fixing body 60 is lowered. At this time, the second lifting block 600 is lifted and the filtered cells C are smoothed on the lower surface of the slide 750 on the upper surface of the filter fixing body 60.

A third slit 701 is formed in the slide block 700 so that the lower surface of the slide 750 is opened.

After the cell C is applied to the slide 750, the filter assembly 60 is taken out from the upper fixed block 300 and the second lifting block 600, Means are provided.

The takeout means includes a pusher block 800 having a pusher 850 that enters the seating groove 601 and reciprocates and a second horizontal rod 810 to which the pusher block 800 is slidably coupled and supported The second lifting block 600 is lifted so that the connecting body 50 and the filter fixing body 60 are engaged and the pusher 850 is moved into the seating groove 601, 800 are moved so that the pusher 850 pushes the coupled connecting body 50 and the filter fixing body 60 to the upper fixed block 300 and the second lifting block 600 as shown in FIG. And to be dropped into the discharge guide 900.

The smear apparatus having the above-described configuration is operated as follows.

First, the cell 100 and the solution solution are received in the container 100, and the container 100, the connecting body 50, and the filter fixing body 60 are joined as shown in FIG. 9A.

10, the first elevating block 500 is lowered and brought into close contact with the upper surface of the upper fixing block 300, and the second elevating block 600 is elevated to lower the lower surface of the upper fixing block 300, . Then, the combined container 100, the connecting body 50 and the filter fixing body 60 are respectively coupled to the first lift block 500, the upper fixed block 300 and the second lift block 600.

Subsequently, when the suction pressure by the vacuum pump is supplied to the suction pipe 610 to suck the solution of cells and solution in the container 100 to the filter fixing body 60, only the solution solution is discharged through the suction pipe 610 The cell C remains in the membrane filter 63. [

15A, the first elevating block 500 is elevated to separate the container 100 from the connecting body 50, and the second elevating block 600 is lowered as shown in FIG. 15B, The filter fixing body 60 is separated from the body 50.

Subsequently, the slide block 700 to which the slide 750 is coupled is moved to the upper side of the filter fixing body 60 as shown in FIG. 15B, and when the second lift block 600 is raised, The upper surface of the slide member 750 comes into contact with the lower surface of the slide 750.

At this time, the cells C remaining on the membrane filter 63 of the filter fixture 60 are smudged on the lower surface of the slide 750.

Subsequently, the slide block 700 is retracted and the second lifting block 600 is lifted so that the filter fixing body 60 is engaged with the lower surface of the connecting body 50. The pusher 850 enters the pusher entering groove 610 when the second lift block 600 is lifted.

15C, the pusher block 800 is moved so that the pusher 850 pushes the coupled connector 50 and the filter fixture 60 down to the discharge guide 900.

Since the above-described smearing apparatus has a structure in which the pipette 54 is formed integrally with the connecting body 50, the structure is simplified and the smearing time is shortened as compared with the conventional smearing apparatus using a pipette.

100 ... container 50 ... connector
56 ... first flange (of connecting body) 60 ... filter fixing body
66 ... second flange (of filter fixing body) 200 ... lower fixing block
300 ... upper fixing block 500 ... first elevating block
600 ... 2nd lift block 700 ... Slide block
750 ... slide 800 ... pusher block
850 ... pusher 900 ... discharge guide

Claims (3)

And a cap member 120 having a through hole 121 formed at a center thereof to be detachably coupled to the container body 110 to open and close the opening, (100); A bottom plate 53 formed to protrude upward at a central portion of the pipette 54 entering the through hole 121 and a bottom plate 53 extending upward from the edge of the bottom plate 53, A lower engaging portion 52 extending downward from an edge of the bottom plate 53 and a connecting member 50 having a first flange 56 formed on the outer periphery thereof, ; And a vacuum suction unit 400 is coupled to the lower part of the intermediate plate 61. The vacuum suction unit 400 is coupled to the lower part of the intermediate plate 61, A second flange 66 formed on the outer circumference of the body 65 and a membrane filter 63 attached to an upper end of the body 65. The filter 65 is attached to the upper surface of the body 65, And a pipette for smearing the cells on the slide 750. The automatic lapping apparatus includes a sample container,
A lower fixing block 200;
A first through hole 301 is formed at an upper side of the lower fixed block 200 and is supported by a plurality of first vertical rods 310 and spaced apart from each other by a predetermined distance and penetrated vertically, An upper fixing block 300 having a first slit 302 slidably engaged with a first flange 56 of the connecting body 50 at an inner periphery of the first slit 301;
A top plate 400 spaced apart from the upper fixing block 300 by a plurality of second vertical bars 410;
A second through hole 501 to which the container 100 is coupled is formed and a seating jaw 502 is formed at an inner periphery of the second through hole 501 to support an end of the container 100, A first lifting block 500 slidably coupled to the second vertical bar 410 to lift up and down the lower end of the container 100 to and from the connecting body 50;
A seating groove 601 on which the filter fixing body 60 is seated is formed and a second slit 602 on which the second flange 66 slides is formed on the inner periphery of the seating groove 601, A suction hole 603 is formed on a bottom surface of the seating groove 601 and a lower portion of the connection body 50 coupled to the upper fixing block 300 is slidably coupled to the first vertical bar 310, A second lifting block 600 which is lifted and lowered to remove the filter fixing body 60;
The first lift block is lowered and the second lift block is raised so that the cell and solution solution in the vessel 100 in a state where the vessel 100, the connector 50, and the filter fixture 60 are coupled, A suction pipe (610) connected to the suction hole (603) so as to be sucked toward the filter fixing body (60) and providing a suction pressure;
A third slit 701 is formed to be engaged with the lower surface of the slide 750 so that the lower surface of the slide 750 is opened. When the second lift block 600 is lowered, the slide 750 is moved toward the upper side of the filter fixing body 60 And a slide block (700)
And the filtered cells are applied to the lower surface of the slide (750) on the upper surface of the filter fixing body (60) while the second lifting block (600) is lifted. Device. The apparatus according to claim 1, further comprising a take-out means for taking out the connector (50) and the filter fixing body (60) from the upper fixed block (300) and the second lift block (600) Automatic lapping device using sample container with pipette. [Claim 6] The apparatus according to claim 2, wherein the takeout means comprises a pusher block (800) having a pusher (850) that enters the seating groove (601)
And a second horizontal rod 810 slidably coupled to and supported by the pusher block 800,
The second lift block 600 is lifted so that the pusher 850 is inserted into the seating groove 601 while the connecting body 50 and the filter fixing body 60 are engaged with each other, And the pusher (850) is moved so as to push the coupled connector (50) and the filter fixture (60) from the upper fixed block (300) and the second lift block (600) Automatic smearing apparatus using sample container.
KR1020160029251A 2016-03-11 2016-03-11 Automatic Cytology Preparing System using a container for picking free medical treatment included pipet KR101685459B1 (en)

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KR20190037493A (en) * 2017-09-29 2019-04-08 (주)셀트라존 Automatic Smear Apparatus for Liquid Base Cytology
KR20190135831A (en) * 2018-05-29 2019-12-09 (주)로봇앤드디자인 Gripping and decoupling device of cytology preparing robot
KR102142054B1 (en) * 2020-01-02 2020-08-06 주식회사 바이오니트 Specimen cell separation container
KR20210020353A (en) * 2019-08-14 2021-02-24 주식회사 예송 Smear Apparatus for Liquid Base Cytology
KR20210020354A (en) * 2019-08-14 2021-02-24 주식회사 예송 Filter Container for Liquid Base Cytology
WO2021133095A1 (en) * 2019-12-27 2021-07-01 주식회사 바이오니트 Container for smearing specimen cells

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KR20190135835A (en) 2018-05-29 2019-12-09 (주)로봇앤드디자인 Discharging device of cytology preparing robot
KR20190135834A (en) 2018-05-29 2019-12-09 (주)로봇앤드디자인 Suction and smearing device of cytology preparing robot
KR102399224B1 (en) * 2020-04-14 2022-05-18 주식회사 예송 Distributed Smear Method Using Filter Container for Liquid Base Cytology
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KR20230026791A (en) 2021-08-18 2023-02-27 주식회사 다이아슈어바이오 Automatic sample collection device, fully automated device for testing virus infection using the same and real time automatic diagnostic system

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KR20190037493A (en) * 2017-09-29 2019-04-08 (주)셀트라존 Automatic Smear Apparatus for Liquid Base Cytology
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KR20210020353A (en) * 2019-08-14 2021-02-24 주식회사 예송 Smear Apparatus for Liquid Base Cytology
KR20210020354A (en) * 2019-08-14 2021-02-24 주식회사 예송 Filter Container for Liquid Base Cytology
WO2021133095A1 (en) * 2019-12-27 2021-07-01 주식회사 바이오니트 Container for smearing specimen cells
KR102142054B1 (en) * 2020-01-02 2020-08-06 주식회사 바이오니트 Specimen cell separation container

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