KR20120024102A - Ring-type microneedle system - Google Patents
Ring-type microneedle system Download PDFInfo
- Publication number
- KR20120024102A KR20120024102A KR1020100086796A KR20100086796A KR20120024102A KR 20120024102 A KR20120024102 A KR 20120024102A KR 1020100086796 A KR1020100086796 A KR 1020100086796A KR 20100086796 A KR20100086796 A KR 20100086796A KR 20120024102 A KR20120024102 A KR 20120024102A
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- South Korea
- Prior art keywords
- microneedle
- ring
- finger
- skin
- present
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
The present invention relates to a microneedle system which effectively absorbs useful substances such as skin cosmetic ingredients or drugs into the skin or delivers them to the body through the skin. The present invention relates to a ring-type microneedle system having a feature that is easy to apply to a topical area, is convenient to use by the user, and is inexpensive.
Description
The present invention relates to a microneedle system which effectively absorbs useful substances such as skin cosmetic ingredients or drugs into the skin or delivers them to the body through the skin. The present invention relates to a ring-type microneedle system having a feature that is easy to apply to a topical area, is convenient to use by the user, and is inexpensive.
The method of applying skin care ingredients or drugs to the skin, or by applying a pack or patch that contains drugs has the advantage of continuous drug delivery, painlessness, and ease of use. Since the stratum corneum layer having a thickness of ˜60 μm prevents the penetration of foreign substances into the body, the absorption rate of the active ingredient is very low. In particular, when the active ingredient is hydrophilic or has a high molecular weight, its absorption rate is further lowered.
In order to effectively deliver the active ingredient has been used a method of administration using injection. However, the conventional needle has a diameter in millimeters and a length in centimeters, causing a lot of pain in subjects by stimulating many pain points present in the skin. In addition, the injection has a disadvantage in that it can not be easily used at home because the procedure is generally only available in hospitals or professional skin care institutions.
In order to solve this problem, microneedle having a diameter of several tens to hundreds of micrometers and a length of several tens to several thousand micrometers has been developed. Since microneedles form micropores in the stratum corneum of the skin, hydrophilic or high molecular weight components can be absorbed into the skin or transmitted through the skin through the formed micropores. The skin absorption rate and the body delivery rate are also increased. In addition, short needles do not penetrate into the dermal layer where the nerves are distributed, and there is no pain. The long needles have smaller diameters and shorter lengths than conventional needles. It greatly reduces pain.
The microneedle system is divided into a form in which the delivery component in the body is included and a form not in the system.
The microneedle system in which the intracellular delivery component is included in the system has a structure having a storage space for storing the intracellular delivery component, such as US Patent 3964482, and a structure in which the intracellular delivery component is coated on the surface of the microneedle, such as US Pat. Is representative. These structures are convenient for the user, but the structure with the storage space should include the storage space, the passage for delivering the drug to the microneedle, etc., which makes the system complicated and difficult to manufacture. In addition, the structure in which the delivery component in the body is coated on the surface of the microneedle has a limitation in that the delivery component in the body must be made in a dried form. In addition, since these systems are composed of the delivery component and the microneedle together, a separate manufacturing facility must be used for each component, and the effect of the treatment for the delivery component on the microneedle or the microneedles during each process and distribution process. There is a drawback in considering the effect of treatment on the delivery components in the body.
The microneedle system in which the delivery component of the body is not included in the system includes a roller type microneedle system as in Korean Patent No. 753872 and a stamp type microneedle system as in US Pat. No. 5487726. These systems are inconvenient to apply the microneedle after applying the intradermal delivery component to the skin or to apply the double needle to apply the intradermal delivery component after applying the microneedle in advance, but the structure is relatively simple and the body is in the manufacturing process and distribution. There is no need to consider the delivery component has the advantage of easy manufacturing.
On the other hand, the roller type microneedle system has a circumference exceeding 6cm when the diameter of the roller head is 2cm, so when applying to shorter parts, the needle applied to the skin is used several times, but the non-applied part is not used. Because of this, it is not suitable for use on topical areas, and has a structure that is inconvenient for the user to use, and is mainly used for a procedure in a hospital or a skin care center.
The stamp type microneedle system is also suitable for use by others in Korean Patent No. 910793 or Korean Patent Application No. 2009-0102336. On the other hand, US Patent 5487726 and Korean Patent Application No. 2008-0077360, etc. has been devised a stamp type microneedle system of a relatively easy form of self-use. Since the stamp type microneedle system can be caught by using a number of fingers including the thumb and index finger, it is possible to tap the wrist or arm to perform a tapping motion or to insert two or more fingers in the finger fitting part. Because of its relatively large area, it is inconvenient when applied to localized areas of the face. In particular, when applying a skin care substance to a topical area such as a wrinkled area of the eye or a spot formed by using a microneedle system, the user looks at the mirror and observes the application area. There is also a screening problem, and if the area of the microneedle is large, there is also a problem that fine holes are formed in the stratum corneum of the unwanted portion. In addition, when used for the purpose of skin care, the feeling of use is also an important factor, the bar-shaped stamp gives the user a somewhat uncomfortable feeling, such as feeling of pressing or hitting.
The present invention is to provide a ring microneedle system having a feature that is easy to apply to a topical area, easy to use by yourself, comfortable feeling, and low cost to solve the problems as described above. do.
The present invention for solving the above problems is a microneedle system for delivering a useful component into or through the skin into the body, a microneedle portion having a microneedle array is formed on the upper surface, the finger on the lower surface of the microneedle It relates to a ring-shaped microneedle system consisting of a finger insert that can be fitted one.
In the present invention, the area of the needle portion is 0.5 to 10 cm 2, the length of the fine needle is 30 μm or more and 500 μm or less, and the distance between the fine needle and the fine needle is preferably one or more times the length of the fine needle.
In the present invention, it is preferable that the microneedle portion and the finger-fitting portion are configured separately so that the user can easily replace the microneedle portion, which is recommended for one-time use in hygiene.
In the present invention, when the finger fitting portion is made of an open structure of the ring, the fitting portion can be opened so that various users having different finger thicknesses can be used even with one model.
In the present invention, any material may be used as long as the material of the microneedle array is not harmful to the human body. In general, the microneedle array is preferably a polymer resin or a metal material.
In the present invention, it is preferable that the microneedle portion including the microneedle array is made of a polymer resin of the same material.
According to the ring-type microneedle system of the present invention as described above, it is easy to apply to a topical site, convenient to use directly by the person, and provides a comfortable feeling of use.
In addition, according to the present invention, it is possible to manufacture a microneedle system having a low unit cost of a product because it is small in volume, simple in structure, and can be used as a model to deliver useful ingredients of various characteristics into or through the skin.
Therefore, by supplying a low-cost microneedle system to the consumer, it is possible to induce a consumer to work for a more hygienic product use.
In addition, according to the present invention, since the active ingredient can be delivered to the fine pores of the stratum corneum of the skin formed by the microneedle, the hydrophilic component or the component having a large molecular weight, which has previously been difficult to deliver through the skin, is easily delivered through the skin.
1 is a perspective view of a ring-shaped microneedle system according to an embodiment of the present invention.
Figure 2 is an application example of the ring-shaped microneedle system according to an embodiment of the present invention.
Figure 3 is a perspective view of a ring-shaped microneedle system consisting of a microneedle portion and a finger-fitting portion according to an embodiment of the present invention.
Figure 4 is a perspective view of the microneedle portion according to an embodiment of the present invention.
5 is a perspective view of the finger fitting according to an embodiment of the present invention.
Figure 6 is a perspective view of the finger fitting according to another embodiment of the present invention.
Hereinafter, the present invention will be described in more detail with reference to the accompanying drawings. However, these drawings are only examples for easily describing the content and scope of the technical idea of the present invention, and thus the technical scope of the present invention is not limited or changed. It will be apparent to those skilled in the art that various changes and modifications can be made within the scope of the technical idea of the present invention based on these examples.
Figure 1 shows a perspective view of a ring-shaped microneedle system according to an embodiment of the present invention. As shown in FIG. 1, the
The ring-
In addition, when applying the skin care substance to the local area such as the wrinkles of the eyes or the spot where the mushrooms are formed by using the microneedle system, the user looks at the mirror and observes the application area. There is a screening problem. In addition, when the area of the microneedle is large, there is a problem in that fine holes are formed in the stratum corneum of the unwanted portion. In the present invention, since the area of the microneedle portion is narrow within and around one finger, it provides a sufficient field of view when the user uses the mirror while observing the application portion, and forms a micropore only in the stratum corneum of the desired portion.
By the structure and object of the said invention, it is preferable that the area of the microneedle part of this invention is 0.5-10 cm <2>. In addition, since the microneedles of the present invention are used for intradermal delivery or in vivo delivery of useful ingredients that can be used by themselves, the microneedles have a length of 30 μm or more so that the microneedles can penetrate to a part of the stratum corneum or a part of the epidermal layer. It is preferable that the microneedle is 500 μm or less, and since the needle should be able to be applied by finger force, it is not preferable that the density of the microneedle is too high. Therefore, the distance between the microneedle and the microneedle is preferably one or more times the length of the microneedle.
In another embodiment of the present invention, as shown in FIG. 3, the
In another embodiment of the present invention, in the ring-type microneedle system, as shown in FIG. 5, the finger
In another embodiment of the present invention in the ring-shaped microneedle system, as shown in Figure 6, the
In the present invention, any material may be used as long as the material of the microneedle array is not harmful to the human body. In general, the microneedle array is preferably a polymer resin or a metal material. In particular, when the material is made of a polymer resin, since the unit cost of the material is relatively low, there is an advantage that the microneedle array can be manufactured more economically. In addition, when the polymer resin is manufactured, the microneedle array and the remaining microneedles can be formed together, so that the microneedles can be made thin so that the aesthetic design can be high and the weight of the system can be minimized to improve user experience. .
The material of the finger fitting part is almost limited, but if the material is made of an excellent elastic force, such as rubber, there is an advantage that does not have to consider the thickness of the different fingers for each user.
1: ring type microneedle system
10: fine needle part
11: top surface 12: fine needle array
13: if
20: finger insertion
100: detachable fine needle part
111: upper surface 112: fine needle array
113: lower surface 120: coupling portion
200: detachable finger clip
210: ring 220: coupling part
300: finger fitting portion having an open structure ring 310: an open structure ring
400: finger insertion part with a large finger contact area
410 ring
420: coupling portion 421: coupling portion side
Claims (7)
A fine needle portion having a fine needle array formed on an upper surface thereof,
Ring type microneedle system consisting of a finger fitting portion that can be inserted into a finger on the lower surface of the microneedle.
Ring area of the microneedle system, characterized in that the area of 0.5 ~ 10 ㎠.
The microneedle has a length of 30 µm or more and 500 µm or less, and the distance between the microneedle and the microneedle is one or more times the length of the microneedle.
Ring microneedle system, characterized in that the microneedle portion and the finger-insertion portion is configured to be easily removable.
Ring type microneedle system, characterized in that the ring structure of the finger insertion portion open.
Ring microneedle system, characterized in that the material of the microneedle array is a polymer resin or metal material.
Ring type microneedle system, characterized in that the fine needle, including the microneedle array made of a polymer resin of the same material.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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KR1020100086796A KR20120024102A (en) | 2010-09-06 | 2010-09-06 | Ring-type microneedle system |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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KR1020100086796A KR20120024102A (en) | 2010-09-06 | 2010-09-06 | Ring-type microneedle system |
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KR20120024102A true KR20120024102A (en) | 2012-03-14 |
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Family Applications (1)
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KR1020100086796A KR20120024102A (en) | 2010-09-06 | 2010-09-06 | Ring-type microneedle system |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2503651A (en) * | 2012-06-18 | 2014-01-08 | Christopher Jack Studden | Microneedle device with freestanding microneedle beads |
WO2014126317A1 (en) * | 2013-02-14 | 2014-08-21 | (주)라온 | Micro-needle therapy device |
WO2015138207A1 (en) * | 2014-03-10 | 2015-09-17 | 3M Innovative Properties Company | Micro-needle device |
KR20160046022A (en) * | 2014-10-17 | 2016-04-28 | (의료)길의료재단 | Micro needle assembly comprising clamping means |
-
2010
- 2010-09-06 KR KR1020100086796A patent/KR20120024102A/en not_active Application Discontinuation
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2503651A (en) * | 2012-06-18 | 2014-01-08 | Christopher Jack Studden | Microneedle device with freestanding microneedle beads |
GB2503651B (en) * | 2012-06-18 | 2014-09-03 | Christopher Jack Studden | A microneedle with free standing micro-needle beads |
WO2014126317A1 (en) * | 2013-02-14 | 2014-08-21 | (주)라온 | Micro-needle therapy device |
KR101471275B1 (en) * | 2013-02-14 | 2014-12-10 | 주식회사 라온 | Microneedle Curer |
WO2015138207A1 (en) * | 2014-03-10 | 2015-09-17 | 3M Innovative Properties Company | Micro-needle device |
JP2017507732A (en) * | 2014-03-10 | 2017-03-23 | スリーエム イノベイティブ プロパティズ カンパニー | Microneedle device |
KR20160046022A (en) * | 2014-10-17 | 2016-04-28 | (의료)길의료재단 | Micro needle assembly comprising clamping means |
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