KR20070033965A - 에스트로젠 수용체 및 사용 방법 - Google Patents

에스트로젠 수용체 및 사용 방법 Download PDF

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Publication number
KR20070033965A
KR20070033965A KR1020067020936A KR20067020936A KR20070033965A KR 20070033965 A KR20070033965 A KR 20070033965A KR 1020067020936 A KR1020067020936 A KR 1020067020936A KR 20067020936 A KR20067020936 A KR 20067020936A KR 20070033965 A KR20070033965 A KR 20070033965A
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KR
South Korea
Prior art keywords
polypeptide
cells
cell
seq
antibody
Prior art date
Application number
KR1020067020936A
Other languages
English (en)
Korean (ko)
Inventor
자오 이 왕
Original Assignee
크레이톤 유니버시티
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Application filed by 크레이톤 유니버시티 filed Critical 크레이톤 유니버시티
Publication of KR20070033965A publication Critical patent/KR20070033965A/ko

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06Antiabortive agents; Labour repressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743Steroid hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
KR1020067020936A 2004-03-10 2005-03-10 에스트로젠 수용체 및 사용 방법 KR20070033965A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US55206704P 2004-03-10 2004-03-10
US60/552,067 2004-03-10
US64346905P 2005-01-13 2005-01-13
US60/643,469 2005-01-13
PCT/US2005/007857 WO2005087811A2 (en) 2004-03-10 2005-03-10 Estrogen receptors and methods of use

Publications (1)

Publication Number Publication Date
KR20070033965A true KR20070033965A (ko) 2007-03-27

Family

ID=34976296

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067020936A KR20070033965A (ko) 2004-03-10 2005-03-10 에스트로젠 수용체 및 사용 방법

Country Status (10)

Country Link
US (6) US7745230B2 (es)
EP (1) EP1730195B1 (es)
JP (2) JP5307393B2 (es)
KR (1) KR20070033965A (es)
CN (2) CN1930188B (es)
AU (1) AU2005222395B2 (es)
CA (1) CA2559144C (es)
ES (1) ES2533002T3 (es)
HK (1) HK1104563A1 (es)
WO (1) WO2005087811A2 (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070033965A (ko) 2004-03-10 2007-03-27 크레이톤 유니버시티 에스트로젠 수용체 및 사용 방법
US8252835B2 (en) * 2006-10-25 2012-08-28 Shenogen Pharma Group Ltd. Compounds and methods for treating estrogen receptor-related diseases
HU0700534D0 (en) 2006-11-24 2007-10-29 Mezoegazdasagi Biotechnologiai Transgenic animal with enhanced immune response and method for the preparation thereof
CN102307595A (zh) * 2009-02-10 2012-01-04 盛诺基医药科技有限公司 治疗***受体相关疾病的抗体及方法
EP2396034A4 (en) * 2009-02-10 2012-11-21 Shenogen Pharma Group Ltd ANTIBODIES AND METHODS FOR TREATING DISEASES ASSOCIATED WITH A STROGEN RECEPTOR
US8815779B2 (en) 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
US8841269B2 (en) * 2010-02-23 2014-09-23 Creighton University Polynucleotides for use in treating and diagnosing cancers
JP2013545969A (ja) * 2010-10-15 2013-12-26 ユニヴェルシテ リブル ドゥ ブリュッセル エストロゲン受容体αポリペプチド配列、並びにその診断および治療用途
JP6046147B2 (ja) * 2011-09-22 2016-12-14 エクスプレッション、パソロジー、インコーポレイテッドExpression Pathology, Inc. がんの評価のための多重mrmアッセイ
WO2013147081A1 (ja) * 2012-03-30 2013-10-03 コニカミノルタ株式会社 生体物質検出方法
CN105263962B (zh) * 2013-03-19 2019-12-31 北京盛诺基医药科技股份有限公司 抗体及用于治疗与***受体相关疾病的方法
WO2014146575A1 (en) 2013-03-19 2014-09-25 Beijing Shenogen Pharma Group Ltd. Antibodies and methods for treating estrogen receptor-associated diseases
WO2015010596A1 (zh) * 2013-07-22 2015-01-29 北京盛诺基医药科技有限公司 一种乳腺癌预后诊断的方法
EP3210144B1 (en) * 2014-10-24 2020-10-21 Koninklijke Philips N.V. Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities
GB201505305D0 (en) * 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
KR101763580B1 (ko) 2015-09-15 2017-08-01 숙명여자대학교산학협력단 인간 글루타티온 s-전달효소 p1-1을 이용한 에스트로겐 수용체 매개된 질환 치료제 스크리닝 방법
CN108191976A (zh) * 2017-12-18 2018-06-22 青岛珅奥基生物工程有限公司 一种抗ER-α36单克隆抗体
CN107987164B (zh) * 2017-12-18 2021-02-19 青岛珅奥基生物工程有限公司 ***受体ER-α36抗原多肽及其单克隆抗体
CN114874326B (zh) * 2022-06-21 2023-01-17 图凌(杭州)生物医药有限公司 一种检测***受体α的单克隆抗体及其制备方法和应用

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EP2396034A4 (en) * 2009-02-10 2012-11-21 Shenogen Pharma Group Ltd ANTIBODIES AND METHODS FOR TREATING DISEASES ASSOCIATED WITH A STROGEN RECEPTOR
US8841269B2 (en) * 2010-02-23 2014-09-23 Creighton University Polynucleotides for use in treating and diagnosing cancers

Also Published As

Publication number Publication date
CN1930188A (zh) 2007-03-14
CA2559144A1 (en) 2005-09-22
US20100285018A1 (en) 2010-11-11
WO2005087811A2 (en) 2005-09-22
CN1930188B (zh) 2012-01-11
US7745230B2 (en) 2010-06-29
US8512952B2 (en) 2013-08-20
US8617833B2 (en) 2013-12-31
US8013127B2 (en) 2011-09-06
CA2559144C (en) 2014-01-21
US8263738B2 (en) 2012-09-11
ES2533002T3 (es) 2015-04-06
US20120321634A1 (en) 2012-12-20
US20120016109A1 (en) 2012-01-19
JP5307393B2 (ja) 2013-10-02
WO2005087811A3 (en) 2006-03-30
US20120322149A1 (en) 2012-12-20
AU2005222395B2 (en) 2012-02-16
HK1104563A1 (en) 2008-01-18
US8551776B2 (en) 2013-10-08
JP5873034B2 (ja) 2016-03-01
AU2005222395A1 (en) 2005-09-22
JP2013153751A (ja) 2013-08-15
EP1730195A2 (en) 2006-12-13
US20130011847A1 (en) 2013-01-10
EP1730195B1 (en) 2015-01-14
CN102504025B (zh) 2015-10-21
JP2007528406A (ja) 2007-10-11
CN102504025A (zh) 2012-06-20
US20070258895A1 (en) 2007-11-08

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