KR20070033965A - 에스트로젠 수용체 및 사용 방법 - Google Patents
에스트로젠 수용체 및 사용 방법 Download PDFInfo
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- KR20070033965A KR20070033965A KR1020067020936A KR20067020936A KR20070033965A KR 20070033965 A KR20070033965 A KR 20070033965A KR 1020067020936 A KR1020067020936 A KR 1020067020936A KR 20067020936 A KR20067020936 A KR 20067020936A KR 20070033965 A KR20070033965 A KR 20070033965A
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61P15/06—Antiabortive agents; Labour repressants
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- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
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- A—HUMAN NECESSITIES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- G—PHYSICS
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- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
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US64346905P | 2005-01-13 | 2005-01-13 | |
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PCT/US2005/007857 WO2005087811A2 (en) | 2004-03-10 | 2005-03-10 | Estrogen receptors and methods of use |
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KR20070033965A true KR20070033965A (ko) | 2007-03-27 |
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US (6) | US7745230B2 (es) |
EP (1) | EP1730195B1 (es) |
JP (2) | JP5307393B2 (es) |
KR (1) | KR20070033965A (es) |
CN (2) | CN1930188B (es) |
AU (1) | AU2005222395B2 (es) |
CA (1) | CA2559144C (es) |
ES (1) | ES2533002T3 (es) |
HK (1) | HK1104563A1 (es) |
WO (1) | WO2005087811A2 (es) |
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KR20070033965A (ko) | 2004-03-10 | 2007-03-27 | 크레이톤 유니버시티 | 에스트로젠 수용체 및 사용 방법 |
US8252835B2 (en) * | 2006-10-25 | 2012-08-28 | Shenogen Pharma Group Ltd. | Compounds and methods for treating estrogen receptor-related diseases |
HU0700534D0 (en) | 2006-11-24 | 2007-10-29 | Mezoegazdasagi Biotechnologiai | Transgenic animal with enhanced immune response and method for the preparation thereof |
CN102307595A (zh) * | 2009-02-10 | 2012-01-04 | 盛诺基医药科技有限公司 | 治疗***受体相关疾病的抗体及方法 |
EP2396034A4 (en) * | 2009-02-10 | 2012-11-21 | Shenogen Pharma Group Ltd | ANTIBODIES AND METHODS FOR TREATING DISEASES ASSOCIATED WITH A STROGEN RECEPTOR |
US8815779B2 (en) | 2009-09-16 | 2014-08-26 | SwitchGear Genomics, Inc. | Transcription biomarkers of biological responses and methods |
US8841269B2 (en) * | 2010-02-23 | 2014-09-23 | Creighton University | Polynucleotides for use in treating and diagnosing cancers |
JP2013545969A (ja) * | 2010-10-15 | 2013-12-26 | ユニヴェルシテ リブル ドゥ ブリュッセル | エストロゲン受容体αポリペプチド配列、並びにその診断および治療用途 |
JP6046147B2 (ja) * | 2011-09-22 | 2016-12-14 | エクスプレッション、パソロジー、インコーポレイテッドExpression Pathology, Inc. | がんの評価のための多重mrmアッセイ |
WO2013147081A1 (ja) * | 2012-03-30 | 2013-10-03 | コニカミノルタ株式会社 | 生体物質検出方法 |
CN105263962B (zh) * | 2013-03-19 | 2019-12-31 | 北京盛诺基医药科技股份有限公司 | 抗体及用于治疗与***受体相关疾病的方法 |
WO2014146575A1 (en) | 2013-03-19 | 2014-09-25 | Beijing Shenogen Pharma Group Ltd. | Antibodies and methods for treating estrogen receptor-associated diseases |
WO2015010596A1 (zh) * | 2013-07-22 | 2015-01-29 | 北京盛诺基医药科技有限公司 | 一种乳腺癌预后诊断的方法 |
EP3210144B1 (en) * | 2014-10-24 | 2020-10-21 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
GB201505305D0 (en) * | 2015-03-27 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel Peptides and combination of peptides for use in immunotherapy against various tumors |
KR101763580B1 (ko) | 2015-09-15 | 2017-08-01 | 숙명여자대학교산학협력단 | 인간 글루타티온 s-전달효소 p1-1을 이용한 에스트로겐 수용체 매개된 질환 치료제 스크리닝 방법 |
CN108191976A (zh) * | 2017-12-18 | 2018-06-22 | 青岛珅奥基生物工程有限公司 | 一种抗ER-α36单克隆抗体 |
CN107987164B (zh) * | 2017-12-18 | 2021-02-19 | 青岛珅奥基生物工程有限公司 | ***受体ER-α36抗原多肽及其单克隆抗体 |
CN114874326B (zh) * | 2022-06-21 | 2023-01-17 | 图凌(杭州)生物医药有限公司 | 一种检测***受体α的单克隆抗体及其制备方法和应用 |
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US4036945A (en) | 1976-05-03 | 1977-07-19 | The Massachusetts General Hospital | Composition and method for determining the size and location of myocardial infarcts |
US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
US4784949A (en) | 1984-04-19 | 1988-11-15 | Cetus Corporation | Universal dominant selectable marker cassette |
WO1986002077A1 (en) | 1984-10-02 | 1986-04-10 | Meade Harry M | Production of streptavidin-like polypeptides |
US5560922A (en) | 1986-05-30 | 1996-10-01 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5788983A (en) | 1989-04-03 | 1998-08-04 | Rutgers, The State University Of New Jersey | Transdermal controlled delivery of pharmaceuticals at variable dosage rates and processes |
US5312752A (en) | 1989-07-31 | 1994-05-17 | Trustees Of Boston University | Specific antibodies against the DNA-binding domain of and immunoassays to determine the presence and functional status of estrogen receptor proteins |
US5053133A (en) | 1990-02-09 | 1991-10-01 | Elias Klein | Affinity separation with activated polyamide microporous membranes |
US5595887A (en) | 1990-07-16 | 1997-01-21 | Bionebraska, Inc. | Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment |
DE69406664T2 (de) * | 1993-06-18 | 1998-06-04 | Biotie Therapies Oy | Zusammensetzungen und diagnostische verfahren unter verwendung von monoklonalen antikoerpern gegen cd44v6 |
WO1997035199A1 (en) | 1996-03-20 | 1997-09-25 | The Scripps Research Institute | Azatide peptidomimetics |
WO1999027946A1 (en) | 1997-12-02 | 1999-06-10 | Chong Kun Dang Corp. | Pharmaceutical composition comprising cyclosporin solid-state microemulsion |
GB9716790D0 (en) | 1997-08-07 | 1997-10-15 | Creative Peptides Sweden Ab | Recombinant DNA molecules comprising multimeric copies of a gene sequence and expression thereof |
US6365146B1 (en) | 1999-04-23 | 2002-04-02 | Rutgers, The State University Of New Jersey | Polymer encapsulation of hydrophobic materials |
JP4926320B2 (ja) | 1999-04-28 | 2012-05-09 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | Vegfの選択的阻害による癌処置のための組成物および方法 |
IT1313552B1 (it) * | 1999-06-29 | 2002-09-09 | European Molecular Biology Lab Embl | Isoforme del recettore alfa degli estrogeni umano |
CA2400915A1 (en) * | 2000-02-22 | 2001-08-30 | Pe Corporation (Ny) | Estrogen receptor alpha variants and methods of detection thereof |
EP1191337B1 (en) | 2000-06-12 | 2007-10-10 | Fujirebio Inc. | Immunoassay for measuring human C-peptide and kit therefor |
EP1401472A4 (en) * | 2001-05-25 | 2005-04-06 | Univ Jefferson | ALTERNATIVE SHAPING FORMS OF PROTEINS AS THE BASIS FOR MULTIPLE THERAPEUTIC MODALITIES |
AU2002315110A1 (en) | 2001-06-15 | 2003-01-02 | Wyeth | Characterization of a membrane estrogen receptor |
US20060240016A1 (en) * | 2001-12-18 | 2006-10-26 | Luc Aguilar | Activity of THAP-family chemokine-binding domains |
US20070015271A1 (en) * | 2002-04-04 | 2007-01-18 | Rosen Craig A | Human secreted proteins |
WO2004016653A2 (en) * | 2002-08-15 | 2004-02-26 | Leukotech A/S | Bactericidal, anti-apoptotic, pro-inflammatory and anti-inflammatory peptides of heparin-binding protein (hbp) or human neutrophil elastase |
US20030044412A1 (en) | 2002-08-26 | 2003-03-06 | Pietras Richard J. | Membrane estrogen receptor-directed therapy in breast cancer |
KR20070033965A (ko) | 2004-03-10 | 2007-03-27 | 크레이톤 유니버시티 | 에스트로젠 수용체 및 사용 방법 |
EP2396034A4 (en) * | 2009-02-10 | 2012-11-21 | Shenogen Pharma Group Ltd | ANTIBODIES AND METHODS FOR TREATING DISEASES ASSOCIATED WITH A STROGEN RECEPTOR |
US8841269B2 (en) * | 2010-02-23 | 2014-09-23 | Creighton University | Polynucleotides for use in treating and diagnosing cancers |
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CN1930188A (zh) | 2007-03-14 |
CA2559144A1 (en) | 2005-09-22 |
US20100285018A1 (en) | 2010-11-11 |
WO2005087811A2 (en) | 2005-09-22 |
CN1930188B (zh) | 2012-01-11 |
US7745230B2 (en) | 2010-06-29 |
US8512952B2 (en) | 2013-08-20 |
US8617833B2 (en) | 2013-12-31 |
US8013127B2 (en) | 2011-09-06 |
CA2559144C (en) | 2014-01-21 |
US8263738B2 (en) | 2012-09-11 |
ES2533002T3 (es) | 2015-04-06 |
US20120321634A1 (en) | 2012-12-20 |
US20120016109A1 (en) | 2012-01-19 |
JP5307393B2 (ja) | 2013-10-02 |
WO2005087811A3 (en) | 2006-03-30 |
US20120322149A1 (en) | 2012-12-20 |
AU2005222395B2 (en) | 2012-02-16 |
HK1104563A1 (en) | 2008-01-18 |
US8551776B2 (en) | 2013-10-08 |
JP5873034B2 (ja) | 2016-03-01 |
AU2005222395A1 (en) | 2005-09-22 |
JP2013153751A (ja) | 2013-08-15 |
EP1730195A2 (en) | 2006-12-13 |
US20130011847A1 (en) | 2013-01-10 |
EP1730195B1 (en) | 2015-01-14 |
CN102504025B (zh) | 2015-10-21 |
JP2007528406A (ja) | 2007-10-11 |
CN102504025A (zh) | 2012-06-20 |
US20070258895A1 (en) | 2007-11-08 |
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