KR20040086987A - Feed additive composition containing wild ginseng culture liquid, fructooligosaccharide, citric acid and yucca schidigera extract - Google Patents

Feed additive composition containing wild ginseng culture liquid, fructooligosaccharide, citric acid and yucca schidigera extract Download PDF

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KR20040086987A
KR20040086987A KR1020030021198A KR20030021198A KR20040086987A KR 20040086987 A KR20040086987 A KR 20040086987A KR 1020030021198 A KR1020030021198 A KR 1020030021198A KR 20030021198 A KR20030021198 A KR 20030021198A KR 20040086987 A KR20040086987 A KR 20040086987A
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feed additive
additive composition
wild ginseng
fructooligosaccharide
citric acid
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KR100493789B1 (en
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강춘성
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주식회사 이앤티
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A23K10/35Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from potatoes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/111Aromatic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/163Sugars; Polysaccharides

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  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Physiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
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  • Health & Medical Sciences (AREA)
  • Fodder In General (AREA)
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Abstract

PURPOSE: A feed additive composition containing wild ginseng culture liquid, fructooligosaccharide, citric acid and a yucca schidigera extract is provided. It improves disease resistance by increasing the volume ratio of serum protein, albumin, globulin and red blood cells and enhances bone density, an egg-laying rate and egg weight by increasing physiological activity when fed to pigs, chickens or the like. CONSTITUTION: The feed additive composition contains 60 to 65% by weight of wild ginseng culture liquid, 30 to 34% by weight of fructooligosaccharide, 3 to 5% by weight of citric acid and 0.5 to 1% by weight of a yucca schidigera extract. The composition increases the amount of weight gain per day, the feed requirement rate and the average rate of weight gain per head when fed to a pig.

Description

산삼배양액을 함유하는 사료첨가제 조성물{omitted}Feed additive composition containing wild ginseng culture liquid

본원발명은 산업용 동물인 닭, 돼지 및 소의 질병에 대한 면역력을 증강시켜 내병성을 높임으로서 항생제의 사용량을 줄이고, 생리활성을 높임에 의해 생산성을 증대시킬 수 있도록 하기 위해 주(主)사료에 첨가하여 사용할 수 있는 사료첨가제 조성물에 관한 것이다.The present invention enhances the immunity to diseases of chickens, pigs and cows of industrial animals to increase disease resistance to reduce the amount of antibiotics used, and to increase the productivity by increasing the physiological activity is added to the main feed It relates to a feed additive composition that can be used.

산업용 동물인 닭, 돼지 및 소등의 생산에 있어서 가장 큰 문제점 중에 하나는 사육환경의 변화로 인해 질병 및 기타 환경적인 요인들에 대한 면역력, 생리활성이 저하되고 있다는 사실이다. 이는 주로 집약적인 대규모 생산방식과 고밀도 사육, 약제의 과다사용, 사료원료의 화학처리제 사용증가, 그리고 가공사료의 급여량 증가 등이 주요원인인 것으로 파악되고 있다. 이들 산업용동물의 질병에 대한 저항성 즉 면익력 및 생리활성이 낮아지면 성장의 정체, 페사 등으로 이어지고 이의 방지를 위해 항생제 등의 약제 사용량을 증대시키게 되면 이는 곧 항생제 등 약제의 생체내 축적으로 이어지는 문제 등을 발생시켜 결국 축산농가의 생산성 및 경제성에 중대한 영향을 미치게 된다. 이에 따라 최근 미국, 유럽 등 선진각국에서는 항생제 등 약제의 인체 유해성문제로 인해 항생제를 대체하고 산업용동물의 면역력을증강시킬 수 있으며 동시에 사료라는 특성을 감안하여 경제성도 확보할 수 있는 사료용첨가제 조성물에 대한 연구에 초점을 맞추고, 이에 대한 연구를 지속적으로 실시하여 왔지만 아직도 뚜렷한 성과를 거두지는 못한 것으로 파악된다. 이에 본원발명자는 산업용동물의 사육에서 가장 중요한 장애요인인 면역력 저하에 따른 항생제 등의 약제의 사용량 증대를 완화시킬 수 있는 산업용 동물의 면역력증강용 사료첨가제 조성물의 개발에 노력을 기울이던 중 최근에 생명공학 기술의 급속한 발전으로 그 성과를 나타내고 있는 조직배양을 통한 산삼 부정근(잔뿌리)의 배양과정에서 발생하는 산삼 부정근을 분리하고 남은 배양액으로서 폐기물로 버려져 왔던 "산삼배양액" 이 산업용 동물의 면역력을 증가시켜 질병의 예방을 통하여 항생제 등의 약제의 사용량을 감소시킬 수 있을 뿐만 아니라 생리작용에도 유익한 영향을 미쳐 고품질의 축산물 생산에도 기여할 수 있다는 사실을 확인하고 본원발명을 완성하기에 이르렀다. 지금 까지는 산삼배양액을 폐기물로 처리하였으므로 본원발명은 산업용폐기물을 사료용 첨가제로 개발하였다는 점에서도 그 의의가 더욱 크다 하겠다.One of the biggest problems in the production of industrial animals such as chickens, pigs, and cattle is the fact that changes in the breeding environment are lowering immunity and biological activity against diseases and other environmental factors. This is mainly due to intensive large-scale production, high-density farming, overuse of pharmaceuticals, increased use of chemicals in feedstocks, and increased feedstuffs. When the resistance to diseases of these industrial animals, that is, the surface benefits and physiological activity, is lowered, it leads to stagnation of growth, pesa, etc., and when the amount of the drug used such as antibiotics is increased to prevent it, this leads to the accumulation of drugs such as antibiotics in vivo. And eventually have a significant impact on the productivity and economics of livestock farmers. Accordingly, in advanced countries such as the United States and Europe, it is possible to replace antibiotics and increase immunity of industrial animals due to human hazards of antibiotics such as antibiotics, and at the same time, it is possible to secure the economical efficiency of feed additives considering the characteristics of feed. It has been focused on research and has been conducted continuously, but it is still not clear. Accordingly, the present inventors have made efforts to develop a feed additive composition for boosting immunity of industrial animals that can alleviate the increase in the use of drugs such as antibiotics due to the lowering of immunity, which is the most important obstacle in the breeding of industrial animals. The wild ginseng culture root, which was removed from the culture of wild ginseng root roots (grass roots) through tissue culture showing rapid results in the development of engineering technology, has been discarded as waste. Through the prevention of the disease, it was confirmed that not only can reduce the amount of the drug such as antibiotics, but also have a beneficial effect on the physiological action and contribute to the production of high-quality livestock products, and came to complete the present invention. Until now, since the wild ginseng culture was treated as waste, the present invention is more significant in that industrial waste was developed as a feed additive.

따라서 본원발명은 폐기물로 처리되던 산삼배양액을 이용하여 돼지, 닭 등 산업용 동물의 면역력을 증가시킴으로써 내병성을 높임으로써 항생제의 사용량을 감소시키고 생리활성을 높여 고품질의 축산물 생산이 가능하도록 하는 면역릭 증강 및 생리활성 증대용 사료첨가제 조성물의 제공을 그 목적으로 한다.Therefore, the present invention increases the immunity of industrial animals such as pigs and chickens by using wild ginseng culture liquid treated as waste, thereby increasing the disease resistance, thereby reducing the amount of antibiotics and enhancing the biological activity, thereby producing high quality livestock products. It is an object of the present invention to provide a feed additive composition for increasing physiological activity.

상기의 목적을 달성하기 위하여, 본원발명은 폐기물로 버려지는 산삼배양액을 사료첨가제로 이용함을 그 특징으로 한다. 더 나아가 본원발명의 또 다른 하나의 특징은 닭, 돼지 등이 섭취시 거부감을 나타내는 산삼배양액이 지니는 고유의 쓴맛을 완화하기 위한 수단으로 여러 가지 감미제 중 그 효과가 가장 뛰어난 것으로 확인된 프락토올리고당을 특정의 비율로 혼합하였고 쉽게 부패되는 산삼배양액의 부패 방지를 위한 수단으로 그 효과가 가장 뛰어난 것으로 인정되는 구연산을 특정비율로 혼합함을 특징으로 하며 사포닌 함량의 증대를 위하여 유카추출액을 선택적으로 부가 할 수 있다. 따라서 일반적으로 축산농가에서 사용되는 본원발명의 사료첨가제 조성물은 산삼배양액, 프락토올리고당, 구연산, 유카추출액로 구성될 수 있다. 특히 그 효과를 증대시키기 위하여 상기 구성성분들을 특정의 비율로 혼합하는 것을 특징으로 한다. 보다 상세하게는 본원발명의 사료용 첨가제 내의 각 구성성분들의 구성비는 액상의 산삼배양액 60-65%, 프락토올리고당 30-34%, 구연산 3-5%, 유카추출액 0.5-1% 로 구성되는 것이 최적의 조합임을 확인하였다. 각 구성성분들의 비율은 본원발명의 본질적인 목적을 벗어나지 않는 범위 내에서 필요에 따라 적정범위 내에서 가감할 수 있음은 물론이다. 물론 이 경우 각 구성성분 비율상의 약간의 변화로 인하여 본원발명이 목적으로 하는 최상의 효과에 미치지 못한다 하더라도 그 것이 본원발명의 기본적인 목적을 달성하는 한 본원발명의 기술적 권리범위 내에 있는 것이라 하겠다.In order to achieve the above object, the present invention is characterized by using a wild ginseng culture liquid as a feed additive to be discarded as waste. Furthermore, another feature of the present invention is a means to alleviate the inherent bitter taste of wild ginseng culture liquids that are rejected by chickens and pigs. It is a means to prevent corruption of wild ginseng culture liquid which is mixed at a specific ratio and easily decomposed, and it is characterized by mixing citric acid which is recognized as the most effective at a specific ratio, and selectively adding yucca extract to increase saponin content. Can be. Therefore, the feed additive composition of the present invention generally used in livestock farms may be composed of wild ginseng culture liquid, fructooligosaccharide, citric acid, and yucca extract. In particular, in order to increase the effect, the components are characterized by mixing at a specific ratio. More specifically, the composition ratio of each component in the feed additive of the present invention is optimally composed of liquid ginseng culture liquid 60-65%, fructooligosaccharide 30-34%, citric acid 3-5%, yucca extract 0.5-1% It was confirmed that the combination. It is a matter of course that the ratio of each component can be added or subtracted within an appropriate range as needed without departing from the essential purpose of the present invention. In this case, even if a slight change in the proportion of each component does not reach the best effect of the present invention, it will be within the technical rights scope of the present invention as long as it achieves the basic purpose of the present invention.

본원발명에서 사용되는 산삼배양액, 프락토올리고당, 구연산, 유카추출액은 사료업계에 종사하는 통상의 기술자라면 쉽사리 구입할 수 있는 것들에 속하는 것이다.The wild ginseng culture liquid, fructooligosaccharide, citric acid, and yucca extract used in the present invention belong to those that can be easily purchased by those skilled in the feed industry.

본원발명에서 산삼배양액은 조직배양을 이용한 산삼부정근의 배양방법에서 배양시킨 산삼부정근을 분리하고 남는 배양액을 말한다. 상기의 산삼배양액은 분리할 당시 형태인 액상형태 또는 액상의 산삼배양액을 스프레이 드라이어 등으로 인공 건조시킨 분말형태와 것을 이용할 수 있다. 액상형태의 산삼배양액을 건조시키는 경우 액상형태의 산삼배양액 1000g당 20g 정도의 건물을 얻을 수 있었다. 따라서 본원발행의 사료첨가제 조성물을 분말형태로 제조할 시에는 상기 건물중 비율을 고려하여 구성성분의 비율을 결정한다. 본원발명에서 이용되는 산삼배양액은 산삼부정근의 조직배양중에 산삼부정근을 분리하고 난 후 남는 부산물로 발생하는 산삼배양액이면 그 효과에 특별한 영향을 미치지 않으므르 어떤 제품이던 이용 가능하다.In the present invention, the wild ginseng culture medium refers to a culture solution that isolates and leaves the wild ginseng paragonus cultured in the culture method of wild ginseng paragonus using tissue culture. The acid ginseng culture liquid may be a liquid form or a powder form obtained by artificially drying the liquid ginseng culture liquid in a spray dryer or the like at the time of separation. When the liquid ginseng culture liquid was dried, approximately 20 g of dry ginseng culture liquid was obtained per 1000 g. Therefore, when preparing the feed additive composition of the present invention in the form of a powder, the ratio of the components is determined in consideration of the ratio of dry matter. The wild ginseng culture liquid used in the present invention is a wild ginseng culture liquid generated as a by-product remaining after separating the wild ginseng root muscle during tissue culture of the wild ginseng root muscle, and thus, any product can be used.

기타 플락토올리고당, 구연산 및 유카추출액은 시중에서 사료의 원료로 판매되고 있는 것이면 어떤 것이던 이용 가능하다. 본원발명의 사료첨가제 조성물은 통상의 배합사료에 필요에 따라 적량 첨가하여 사용할 수 있으며 1 - 2% 내외가 경제적인 관점에서 가장 적정한 것으로 인정되며, 하기 실시예에서는 적용동물을 닭 및 돼지의 사양으로 한정하였으나 소의 사육에서도 닭 및 돼지와 동일 또는 유사한 한 효과를 얻을 수 있을 것으로 기대된다.Other placto-oligosaccharides, citric acid and yucca extracts can be used as long as they are commercially available as feed ingredients. The feed additive composition of the present invention can be used by adding an appropriate amount to a conventional blended feed as needed, and it is recognized that the most suitable from the economical point of view of about 1-2%, in the following examples, the application animal to chicken and pig specifications Although limited, cattle breeding is expected to achieve the same or similar effects as chickens and pigs.

이하 실시예를 통하여 본원발명을 상세히 설명하나, 본원발명의 기술적범위는 이에 한정되지 아니한다.Hereinafter, the present invention will be described in detail with reference to Examples, but the technical scope of the present invention is not limited thereto.

〈실시예1〉<Example 1>

혼합기에 건물중이 2%인 액상의 산삼배양액 64kg, 프락토올리고당 30kg ,구연산 5kg, 유카추출액 1kg의 비율로 원료를 넣고 10분간 혼합하여 본원발명이 면역력 및 생리활성 증강용 액상의 사료첨가제 조성물을 얻었다.Into the mixer, the raw ginseng culture medium with 2% dry weight of 64kg, fructooligosaccharide 30kg, citric acid 5kg, yuka extract 1kg and mixed for 10 minutes, the present invention is a liquid feed additive composition for enhancing immunity and physiological activity Got it.

실시예1에 의해 얻어진 본원발명의 사료첨가제 조성물을 닭의 사양(산란계) 시통상의 배합사료에 1% 혼합 투여하여 영향을 시험해본 결과 아래 표 1 - 5에서와 같이 본원발명의 사료첨가제 조성물이 면역력과 관계되는 혈청단백의 변화, 적혈구 용적 등과 기타 골밀도, 산란율 및 난중 등 다양한 부분에서 면역력 및 생리활성을 증가시키는 현격한 효과를 나타낸다는 결과를 얻을 수 있었다.As a result of testing the effect of the feed additive composition of the present invention obtained by Example 1 by mixing 1% mixed formulations of chicken (traditional laying hens) in the conventional diet, the feed additive composition of the present invention has immunity as shown in Tables 1 to 5 below. The results show that the serum protein changes, erythrocyte volume, and other factors, such as bone density, spawning rate and egg weight, have a marked effect of increasing immunity and physiological activity.

〈표 1〉 닭의 혈청단백 변화<Table 1> Serum protein changes in chicken

〈표 2〉 닭의 적혈구 용적 변화<Table 2> Changes in Red Blood Cell Volume in Chickens

〈표 3〉 닭의 골밀도 변화<Table 3> Changes in Bone Mineral Density in Chickens

〈표 4〉 난중의 변화〈Table 4〉 Changes in the Lanyard

〈표 5〉 산란율의 변화<Table 5> Changes in Scattering Rate

실시예1에 의해 얻어진 본원발명의 사료첨가제 조성물을 이유 자돈(갓난 돼지)의 사양 시 통상의 배합사료에 1%에 혼합 투여하여 영향을 시험해본 결과 아래 표 6에서와 같이 본원발명의 사료첨가제 조성물이 면역력, 생리활성의 증강작용의 결과로 폐사두수, 일당증체량 및 사료요구율 등에서 현격한 효과를 나타낸다는 결과를 얻을 수 있었다.As a result of testing the effect of the feed additive composition of the present invention obtained according to Example 1 by mixing and administering 1% to a conventional compound feed in the specification of weaning pigs (new pigs), the feed additive composition of the present invention as shown in Table 6 below. As a result of the enhancement of immunity and physiological activity, the results showed a marked effect on mortality, daily gain and feed demand.

〈표 6〉 양돈에 대한 생산성 향상 효과<Table 6> Productivity Improvement Effects on Swine

본원발명의 제조방법에 의해 제조된 산삼배양액을 함유한 사료첨가제 조성물을 닭에게 급여하면 닭의 혈액내 혈청단백, 알부민, 글로불린 및 적혈구의 용적비율을 증대시킴으로서 양계 및 육계시에 개체의 면역력 강화로 항병력을 증강시켜 양계 및 육계의 생산성을 증대시키는 효과를 얻을 수 있을 뿐만 아니라, 생리활성을 증대시켜 골밀도, 산란율 및 난중를 증대시키는 효과도 얻을 수 있다. 다른 한편으로는 본원발명의 산삼배양액을 함유한 사료첨가제 조성물을 돼지에 급여하면 면역력 및 생리활성의 증강작용의 결과로 폐사두수, 사료요구율 및 일당증체량 등에서 양호한 효과를 나타내 양돈의 생산성을 증대시키는 효과를 얻을 수 있다. 본원발명은 폐기물로 처리되던 산삼배양액을 사료로 활용한다는 또 다른 효과가 있다.Feeding the feed additive composition containing wild ginseng culture solution prepared by the method of the present invention to the chickens increases the volume ratio of serum protein, albumin, globulin and red blood cells in the chicken blood, thereby enhancing the immunity of the individual in poultry and broilers. Not only can the effect of increasing the productivity of poultry and broiler chickens by increasing the history of anti-violence, but also the effect of increasing the physiological activity to increase bone density, spawning rate and egg weight. On the other hand, feeding the feed additive composition containing the wild ginseng culture solution of the present invention to pigs has the effect of enhancing the productivity of pigs, resulting in a good effect on the number of lungs, feed rate and daily gain as a result of the enhancement of immunity and physiological activity. Can be obtained. The present invention has another effect of using the wild ginseng culture liquid was treated as waste feed.

Claims (5)

산삼배양액, 프락토올리고당, 구연산, 유카추출액을 포함하여 구성되는 것을 특징으로 하는 사료첨가제 조성물 .Feed additive composition comprising a wild ginseng culture liquid, fructooligosaccharide, citric acid, yucca extract. 제1항에 있어서 건물중이 2%인 액상의 산삼배양액이 60-65%, 프락토올리고당이 30-34%, 구연산이 3-5%, 유카추출액이 0.5-1%의 비율로 구성되는 것을 특징으로 하는 사료첨가제 조성물The liquid ginseng culture liquid of 2% in dry matter is 60-65%, fructooligosaccharide is 30-34%, citric acid is 3-5%, and the yucca extract is 0.5-1%. Feed additive composition characterized in 제1항에 있어서 액상의 산삼배양액이 64%, 프락토올리고당이 30%, 구연산이 5%, 유카추출액이 1%의 비율로 구성되는 것을 특징으로 하는 사료첨가제 조성물The feed additive composition according to claim 1, wherein the liquid wild ginseng culture liquid comprises 64%, fructooligosaccharide 30%, citric acid 5%, and yucca extract in a ratio of 1%. 제1항 내지 제3항의 어느 한 항 따른 양계용 사료첨가제 조성물 .Feed additive composition for poultry according to any one of claims 1 to 3. 제1항 내지 제3항의 어느 한 항에 따른 양돈용 사료첨가제 조성물 .Pig feed composition according to any one of claims 1 to 3.
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100934252B1 (en) * 2009-06-10 2009-12-28 한방바이오 주식회사 Its feed and an additive composition for poultry containing wild ginseng cultured root
CN103893388A (en) * 2014-04-15 2014-07-02 李萍 Traditional Chinese medicine for treating bone mineral density reduction of patient with hyperthyroidism and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100934252B1 (en) * 2009-06-10 2009-12-28 한방바이오 주식회사 Its feed and an additive composition for poultry containing wild ginseng cultured root
CN103893388A (en) * 2014-04-15 2014-07-02 李萍 Traditional Chinese medicine for treating bone mineral density reduction of patient with hyperthyroidism and preparation method thereof

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