KR20010055274A - Health augmentation food for the anti fatigue - Google Patents

Health augmentation food for the anti fatigue Download PDF

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KR20010055274A
KR20010055274A KR1019990056435A KR19990056435A KR20010055274A KR 20010055274 A KR20010055274 A KR 20010055274A KR 1019990056435 A KR1019990056435 A KR 1019990056435A KR 19990056435 A KR19990056435 A KR 19990056435A KR 20010055274 A KR20010055274 A KR 20010055274A
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vitamin
health
fatigue
lecithin
rats
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KR1019990056435A
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Korean (ko)
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김재수
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김재수
대성약품 주식회사
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Publication of KR20010055274A publication Critical patent/KR20010055274A/en

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    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/30—Encapsulation of particles, e.g. foodstuff additives

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: Provided is an antifatigue health supplementary food containing insam extract and multi-vitamins with active principles such as calcium, iron and magnesium, which can prevent various kinds of diseases caused by fatigue and keep physical health. CONSTITUTION: The health supplementary food is prepared by mixing 160mg of insam extract(ginseng saponin 80mg/g total solid 60%), 15μg of powdered vitamin A, 1.2mg of vitamin B1, 0.05mg of vitamin B2, 0.4mg of vitamin B6, 18.2mg of vitamin C, 0.27mg of vitamin E, 4.00mg of nicotinamide, 10.00mg of calcium pantothenate, 15.00mg of magnesium oxide, 5.00mg of zine oxide, 15.00mg of ferrous lactate, 34.00mg of bone meal, 28.00mg of bee wax, 28.4mg of palm oil, 301.00mg of bean oil, and 10.5mg of lecithin. The mixture is sealed up in a soft capsule by 700mg and is to be taken 2-3 times a day.

Description

항피로용 건강 보조식품{HEALTH AUGMENTATION FOOD FOR THE ANTI FATIGUE}HEALTH AUGMENTATION FOOD FOR THE ANTI FATIGUE}

본 고안은 항피로(抗疲勞)용 건강 보조식품에 관한 것이다.The present invention relates to anti-fatigue health supplements.

최근에, 식생활에서 인체에 섭취되어야 영양성분중 건강적 측면에서 고려된 부족한 영양소를 보충하기 위한 여러가지 형태와 종류의 건강보조식품이 알려저 있다.Recently, various forms and types of dietary supplements have been known to compensate for the lack of nutrients considered in the health aspects of nutrition by being consumed by the human body in diet.

일반적인 건강 보조식품은 신체발육을 목적으로 하는 보조식품과 또 피로를 회복하기 위하여 복용하는 보조식품이 주류를 이루고 있다.The general health supplements are made up of supplements for the purpose of physical development and supplements taken to relieve fatigue.

국내에서 가장 많이 사용되는 인삼을 주제로 하는 건강보조식품은 주로 피로를 회복하는데 주안점을 두고 있으며 인삼제제가 병약한 자의 치료목적의 한약제로 사용되기 때문에 그러한 관점에서 약한자의 건강회복을 목적으로 하는 건강보조식품에 주로 이용되었다The health supplement food, which is the theme of ginseng used most in Korea, mainly focuses on recovering from fatigue, and since ginseng is used as a herbal medicine for the treatment of the sick, health for the health of the weak is in view. Mainly used in supplements

그러나 건강을 유지하는데는 병약한 몸을 치료하여 건강하게 회복시키고 또 피로중에 있는 몸을 원기 있게 회복하는 것도 중요하지만, 인체에 피로를 견딜 수 있는 내성을 주는 것이 무엇보다 중요하다. 평소에 피로를 덜 느끼는 사람은 병에도 덜 감염되는 사실이 여러가지 의학적으로 입증되고 있다. 그러나 상기한 바와 같이 건강이 약화된 후에 회복을 위한 건강보조식품의 종류는 많은데 피로가 덜 오는 체질적 생리적 보강을 위한 건강보조식품은 그 종류가 극히 적다.However, in order to maintain health, it is also important to treat the sick body to restore health and refresh the body in fatigue, but to give the human body resistance to fatigue is more important than anything else. Medically proven to be less susceptible to people who usually feel less tired. However, as described above, there are many kinds of health supplement foods for recovery after health weakness, but there are very few kinds of health supplement foods for physical and physiological reinforcement that are less fatigued.

인체의 항피로 요소는 여러가지 요인중 운동중 간당원(肝糖原)이 높고 혈청요소질소(Urea nitogen)량이 낮어야 하는 것이 건강 의학계의 일반적인 견해이다.It is a general opinion of the health medical community that the anti-fatigue component of the human body should be high in glycemic sources and low serum urea nitrogen during exercise.

일반적으로 정신적, 육체적 운동을 하게 되면 간당원이 낮아지고 혈청요소질소량은 증가되어, 간당원이 높지 않은 사람일 수록 피로감이 빨리 오고 혈청요소질소량이 높을 수록 피로감이 빨리 온다. 즉 신체적 지구력이 떨어저서 피로가 속히 오고 각종 질병에 대한 저항력이 저하되므로 병약되기 쉽다. 물론 신체가 건강하고 음식의 섭생이 양호한 사람인 경우, 그렇지 못한 사람 보다 같은 조건에서 피로감이 덜 하고 병에 대한 저항성도 물론 높다. 그러나 모든 사람이 모두 건강한 것은 아니므로 피로감이 덜 올수 있는 영양섭취가 무엇보다 중요하다.Generally, mental and physical exercise results in lower glycemic members and increased serum urea nitrogen levels, so that those who do not have high glycemic sources get tired quickly, and the higher the amount of serum urea nitrogen, the faster the fatigue comes. In other words, physical endurance is low, fatigue quickly comes, and resistance to various diseases is lowered, so it is easy to be sickly. Of course, if the body is healthy and the diet is good, less fatigue and the disease resistance of the same conditions than those who do not. However, not everyone is healthy, so nutrition is less important than anything else.

본 발명은 이러한 사실에 주안점을 두고 인체에 평소 간당원을 높이는 동시 혈청 요소는 낮게 유지하는데 유효한 건강보조식품을 개발한 것이다.The present invention focuses on this fact and has developed a dietary supplement that is effective to keep the serum elements at the same time raising the usual glycosides low in the human body.

즉 인체에 가장 약리작용이 높은 것으로 알려진 사포닌성분을 다량 함유하고 있는 인삼 엑기스에 비타민A,B1,B2, B6,B12,비타민C,D3, 비타민E, 레시틴, 칼슘, 산화마그네슘, 훼로랙태이트, 팜유, 대두유등, 미량이지만 인체의 건강에 유효성분을 배합하여 700㎎단위 캅셀로 만들어 1일 2-3번 1알씩 상시 복용하므로서 신체의 간당원을 높히고 혈청요소질소를 감소시키어 항피로 능력을 높힐 수 있게 한 것이다,That is, ginseng extract containing a large amount of saponin, which is known to have the highest pharmacological action in the human body, is contained in vitamin A, B 1 , B 2 , B 6 , B 12 , vitamin C, D 3 , vitamin E, lecithin, calcium, magnesium oxide , Ferrocactate, palm oil, soybean oil, etc., but the amount of active ingredients to the body health of 700mg unit capsules to take one or two 2-3 times a day to increase the body's glycosides and reduce serum urea nitrogen In order to increase the ability to anti-fatigue,

이는 종래의 피로회복용 건강보조식품과 다른 예방적 기능을 가진 건강보조식품인 것이다.This is a dietary supplement with a preventive function different from the conventional fatigue dietary supplement.

(실시예)(Example)

본 발명의 건강보조식품의 조성은 다음과 같다.The composition of the health supplement food of the present invention is as follows.

인삼엑기스 (Ginseng saponin 80mg/g totale solid 60%) 160㎎Ginseng Extract (Ginseng saponin 80mg / g totale solid 60%) 160mg

비타민 A분말(Retinol 50%) 15㎍15 ㎍ of Vitamin A Powder (Retinol 50%)

비타민 B1 (Thiamine HCl) 1.2㎎Vitamin B1 (Thiamine HCl) 1.2mg

비타민 B2 (Riboflavin) 0.05㎎Vitamin B2 (Riboflavin) 0.05mg

비타민 B6 (Pyridoxine HCl) 0.4㎎Vitamin B6 (Pyridoxine HCl) 0.4 mg

비타민 C (Ascorbic Acid) 18.2㎎Vitamin C (Ascorbic Acid) 18.2mg

비타민 E 0.27㎎Vitamin E 0.27 mg

니코틴아미드(Nicotinamide) 4.00㎎Nicotinamide 4.00mg

칼슘판토티내이트(Calcium Pantothenate) 10.00㎎Calcium Pantothenate 10.00mg

마그네슘옥사이드(Magnesium Oxide) 15.00㎎Magnesium Oxide 15.00mg

진옥사이드 (Zine Oxide) 5.00㎎Zine Oxide 5.00mg

훼로스랙태이트(Ferrous Lactate) 15.00㎎Ferrous Lactate 15.00mg

골분(Bone meal :Calcium 30%) 34.00㎎Bone meal (Calcium 30%) 34.00mg

밀납(Bee Wax) 28.00㎎Bee Wax 28.00mg

팜 오일(Palm Oil) 28.4㎎Palm Oil 28.4mg

대두유 (Bean Oil) 301.00㎎Soybean Oil 301.00mg

레시틴(Lecithin) 10.5㎎Lecithin 10.5mg

상기 조성물은 균일하게 배합하여 1캅셀 700㎎ 단위로 충전하여 출하하며, 1일 2-3회 1캅셀씩 복용하는 것이다.The composition is uniformly formulated and shipped in 700 mg units of 1 capsule, one capsule 2-3 times a day.

본 발명의 실시예에서 사용되는 인삼엑기스는 세척된 인삼을 30-70% 온도60-70℃에서 발효하여 원심분리기로 15000rpm의 회전속도로 원심분리하여 50±5℃로 농축시킨 흑갈색의 농축액을 사용하며 기타 배합성분은, 식품학 및 의학적으로 복용가능하게 정선제조된 시판의 것을 사용한다.The ginseng extract used in the embodiment of the present invention is fermented washed ginseng at 30-70% temperature 60-70 ℃ centrifuged at a rotational speed of 15000rpm in a centrifuge using a dark brown concentrate concentrated to 50 ± 5 ℃ And other ingredients, commercially available foods and medically selected.

본 발명의 건강보조식품에 대한 항피로에 대하여 다음과 같이 실험하였다.Antifatigue for the health supplement of the present invention was tested as follows.

1, 재료 및 방법1, materials and methods

1.1 시료1.1 Sample

본 발명의 상기 조성의 건강보조식품1000캅셀을 준비하였다.A health supplement 1000 capsules of the above composition of the present invention was prepared.

1.2 실험동물1.2 Experimental Animals

중국인민해방군 군사의학 과학원 실험동물센터에서 번식한 건강한 곤명(昆明)종 수컷(비준번호 경동자(京動字)제8707MO 1호)체중 18-22gHealthy Kunming Males Breeding at the Experimental Animal Center of the Military Medical Science Institute of the People's Liberation Army of China (No. 8707MO No. 1) Weight 18-22g

1.3 사용량 선택1.3 Usage Selection

본 발명의 건강보조식품(이하 시제(試劑)라 함)의 1일 인체 추천량은 2.0g/60kg.bw이며 인체 추천량의 0, 5, 10, 30배로 쥐의 위에 투여 하였다. 즉 쥐의 위에 투입하는 량은 0, 0.17, 0.33, 1.00/kg.bw이다. 쥐의 위에 매일 0.4mL/20g,bw 농도로 배합하고 증류수로 대조하여 30일동안 연속하여 쥐의 위에 직접 투여하였다.The daily human recommended amount of the dietary supplement (hereinafter referred to as tense) of the present invention was 2.0g / 60kg.bw and was administered to the stomach of rats at 0, 5, 10, 30 times the human recommended amount. That is, the amount injected into the rat's stomach is 0, 0.17, 0.33, 1.00 / kg.bw. Daily concentration of 0.4mL / 20g, bw in the rat stomach was administered and directly administered to the rat stomach for 30 consecutive days in contrast to distilled water.

1.4 측정기구 및 세제1.4 Measuring Instruments and Detergents

수영상자(약50cm×50cm×40cm) 청평, 아연도금철판,721분광광도계, 요소질소측정세제함(아세틸-옥심(oxime),농유산(硫酸),5%염소초산(증류수로 배합)(TCA),포도당 표준액100㎎/dLSwimming box (approx. 50 cm x 50 cm x 40 cm) Cheongpyeong, galvanized iron plate, 721 spectrophotometer, urea nitrogen measurement detergent (acetyl-oxime, concentrated acid, 5% chloric acid (mixed with distilled water) (TCA) Glucose standard solution 100 mg / dL

안드라센(anthracene) 아세톤(ketone)시제:Andracene acetone reagents:

(1) 72% 유산의 배합: 유리컵에 280mL증류수를 넣고 고순도의 농유산을 넣는다 (분석순 비중 1.84)720mL(1) 72% lactic acid formulation: 280 mL of distilled water is added to a glass cup, and high-purity agricultural oil is added (analysis order specific gravity 1.84) 720 mL

(2) 안드라센(anthracen) 아세톤(ketone)시제의 배합:(2) Formulation of andracene acetone ketone

유산온도가 80-90℃로 내려 왔을 때 500㎎의 순 안드라센 아세톤을 넣고 10g의 고순도 유산을 유리컵에 혼합하여 적당히 흔들어 준다.When the lactic acid temperature is lowered to 80-90 ℃, add 500 mg of pure andrasene acetone and shake 10g of high purity lactic acid in a glass cup.

1.5 실험방법1.5 Experimental Method

1.5.1 수영부하중 실험1.5.1 Swimming load test

쥐에게 마지막 시제를 투여한 30분후 수심 30㎝, 수온 25℃+0.1℃에서, 쥐꼬리에 체중 5%의 아연도금판을 매어 달아 수영장에서 수영을 한다. 쥐의 수영기록은 수영시작한 시접부터 사망시점까지를 쥐의 수영시간(t/min)으로 간주한다.Thirty minutes after the last tense, the rats are immersed in a swimming pool with a galvanized sheet of 5% weight attached to the rat tail at a depth of 30 cm and a water temperature of 25 ° C + 0.1 ° C. Rat swimming records refer to the swimming time (t / min) of rats from the start of swimming to death.

1.5.2 혈청요소질소측정 : 아세틸-옥심1.5.2 Serum Urea Nitrogen: Acetyl-Oxime

쥐에게 마지막 시제를 투여한 30분 후에 온도30℃에서 90분동안 수영한 후 60분동안 안정을 취한다음 죽여 안구에서 0.5mL 을 체혈한다. 4℃에서 3시간 방치한 다음 1500회전/분 속도로 15분간 회전한 후 아세틸-옥심(oxime)을 사용하여 혈청을 채취하여 520㎚파장 비색에서 요소질소를 측정한다.Thirty minutes after the last tense administration, the rats were allowed to swim for 90 minutes at a temperature of 30 ° C, rested for 60 minutes, and then bleed 0.5 mL from the eye. After leaving for 3 hours at 4 ° C. and rotating for 15 minutes at 1500 revolutions / minute, serum was collected using acetyl-oxime and urea nitrogen was measured at 520 nm wavelength colorimetric.

1.5.3 간당원측정: 안드라센 아세톤방법1.5.3 Glucose Measurement: Andrasene Acetone Method

쥐에게 마지막 시제를 투여한 30분 후에 온도30℃에서 90분동안 수영한 후 즉시 쥐를 죽여 간장을 채취하여 생리식염수로 깨끗이 씻은 후에 여과지를 사용하여 정확하게 200㎎를 채취한다. 모든 시험관에 4mL TCA를 넣어 1분동안 액체를 추출하여 원심관에 부어 3000회전/분 속도로 회전시키어 맑은 액을 다른 시험관에 넣어 둔다. 침전중에 다시 4mL TCA를 넣고 1분동안 액체를 추출하여 15분간 원심회전시키어 맑은 액을 채취하여 제1차 맑은 액과 충분히 혼합한다.After 30 minutes of the last tense administration to the rats, swim for 30 minutes at a temperature of 30 ° C, immediately kill the rats, collect the liver, wash them clean with physiological saline, and collect 200 mg correctly using filter paper. Add 4 mL TCA to all test tubes, extract the liquid for 1 minute, pour into the centrifuge tube, rotate at 3000 revolutions per minute, and place the clear solution in another test tube. During precipitation, add 4 mL TCA again, extract the liquid for 1 minute, and centrifugally rotate for 15 minutes to obtain a clear liquid, which is sufficiently mixed with the first clear liquid.

안드라센 (anthracene)아세톤(ketone)을 사용하여 620㎚파장비색에서 간당원을 측정한다.Glucose sources are measured at 620 nm wavelength using anthracene acetone.

1.5.4 유산(乳酸)측정1.5.4 Lactic acid measurement

쥐에게 마지막 시제를 투여한 30분후에 쥐에 다른 부착물이 없는 상태로 30℃에서 10분동안 수영한 후 ① 운동전 ② 운동후 ③ 운동후30분에 각각 20㎕을 채혈하여 피막액에 넣어 충분히 혼합한 다음 투명해지면 유산측정기를 이용하여 측정한다.After 30 minutes of the last tense administration, the rats swim for 10 minutes at 30 ° C with no other attachments. ① Before exercise ② After exercise ③ At 30 minutes after exercise, 20 μl of blood is collected and put into the coating solution. After mixing, the solution is measured using a lactic acid meter.

1.6 실험수치 : 편차분석1.6 Experimental Value: Deviation Analysis

2. 결과2. Results

2.1 쥐의 수영시간에 주는 영향2.1 Effects on Rat Swimming Time

투여량(g/kg)Dose (g / kg) 동물수(마리)Animal count (mari) 수영시간(초)Swimming time (seconds) 00 1313 567.2±132.6567.2 ± 132.6 0.170.17 1313 608.8±347.5608.8 ± 347.5 0.330.33 1313 685.7±357.9685.7 ± 357.9 1.00331.0033 1313 855.1±465.9*855.1 ± 465.9 *

*:(P＜0.05)* :( P <0.05)

상기표에서 쥐에게 본 발명의 시제를 30일동안 다른 투여량으로 투여한 결과 투여된 쥐의 수영시간이 길었고 투여량이 많은 쥐가 수영시간이 가장 길게 연장되었다. 이는 쥐의 항피로 작용이 높은 사실을 알 수 있다.In the above table, the administration of the present invention to the rats at different doses for 30 days resulted in the long swimming time of the mice administered and the longest dose of the mice was extended. This can be seen that the anti-fatigue effect of the rat is high.

2.2 운동시에 혈청요소질소에 주는 영향2.2 Effects on Serum Urea Nitrogen in Exercise

투여량(g/kg)Dose (g / kg) 동물수(마리)Animal count (mari) 혈청요소질소(㎎/d/L)Serum Urea Nitrogen (mg / d / L) 00 1414 31.22 ±2.6831.22 ± 2.68 0.170.17 1414 27.98 ±3.10*27.98 ± 3.10 * 0.330.33 1414 27.14 ±1.80*27.14 ± 1.80 * 1.001.00 1212 26.30 ±1.79*26.30 ± 1.79 *

*: P ＜0.01*: P <0.01

상기 표 2에서 쥐에게 본 발명의 시제를 30일 동안 다른 투여량으로 투여한 결과 혈청요소질소가 현저하게 차이가 있었다. 시제의 투여량이 많은 쥐의 혈청요소질소의 량이 적었다. 이는 쥐의 항피로 작용이 높은 것을 알 수 있다.In Table 2, the serum urea nitrogen was significantly different as a result of administering the formulation of the present invention to the rats at different dosages for 30 days. The amount of serum urea nitrogen in rats with high doses of tense was low. It can be seen that the anti-fatigue effect of the rat is high.

2.3 쥐의 운동시 간당원의 소모량에 주는 영향2.3 Effect on the Consumption of Glucose Sources in Rat Exercise

투여량(g/kg)Dose (g / kg) 동물수(마리)Animal count (mari) 간당원(㎎/100g 간조직)Liver sugar source (mg / 100g liver tissue) 00 1313 46.8 40.746.8 40.7 0.170.17 1212 1159.8 950.6*1159.8 950.6 * 0.330.33 1313 621.6 517.7*621.6 517.7 * 1.001.00 1010 131.2 141.0131.2 141.0

*:P＜0.01*: P <0.01

상기표 3 에서 줴에게 본 발명의 시제를 30일 동안 다른 투여량으로 투여한 결과 저, 중, 고의 시제 투여량에 따라 간당원이 현저하게 차이가 있었다.In Table 3, when the tense of the present invention was administered to other doses for 30 days, the glycosides were markedly different according to the low, medium, and high doses.

2.4 쥐의 운동후 혈유산소의 높낮이에 주는 영향2.4 Effects on Hematocrit Levels after Exercise in Rats

(mmol/L)(mmol / L) 투여량(g/kg)Dose (g / kg) 동물수(마리)Animal count (mari) 운동전Pre-workout 운동후 즉시Immediately after exercise 차이Difference 00 1414 3.08 ±0.363.08 ± 0.36 7.29 ±1.547.29 ± 1.54 4.21 ±1.574.21 ± 1.57 0.170.17 1313 4.11 ±0.864.11 ± 0.86 8.22 ±1.138.22 ± 1.13 4.11 ±0.884.11 ± 0.88 0.330.33 1313 3.95 ±0.593.95 ± 0.59 7.57 ±1.487.57 ± 1.48 3.62 ±1.303.62 ± 1.30 1.001.00 1313 3.51 ±1.643.51 ± 1.64 7.25 ±1.217.25 ± 1.21 3.74 ±1.923.74 ± 1.92

상기 표4에서 쥐에 본 발명의 시제를 30일 동안 다른 투여량으로 투여한 결과 각 투여량의 운동후의 혈유산소의 높낮이를 측정한 결과 차이가 없었다.As shown in Table 4, the rats of the present invention were administered at different doses for 30 days.

2.5 쥐의 운동후 혈유산소 제거도에 주는 영향2.5 Effects on Hemoglobin Removal after Exercise in Rats

(mmol/L)(mmol / L) 투여량(g/kg)Dose (g / kg) 동물수(마리)Animal count (mari) 운동전Pre-workout 운동후 즉시Immediately after exercise 차이Difference 00 1414 7.29 ±1.547.29 ± 1.54 2.36 ± 0.762.36 ± 0.76 4.93 ±1.414.93 ± 1.41 0.170.17 1313 8.22 ±1.138.22 ± 1.13 3.14 ±1.073.14 ± 1.07 5.08 ±1.415.08 ± 1.41 0.330.33 1313 7.57 ±1.487.57 ± 1.48 2.57 ±1.222.57 ± 1.22 5.00 ±1.625.00 ± 1.62 1.001.00 1313 7.25 ±1.217.25 ± 1.21 3.51 ±1.373.51 ± 1.37 3.74 ±1.893.74 ± 1.89

상기 표5에서 혈유산소제거도도 큰 차이가 없었다.In Table 5, hemoglobin removal also did not have a big difference.

3. 결론3. Conclusion

본 발명의 건강보조식품을 0, 0.17, 0.33, 1.00g/kgbw.day를 30일간 연속적으로 쥐의 위에 투여한 결과 쥐의 수영시간이 현저하게 연장되었으며, 쥐의 운동시 혈청요소질소 수평이 낮아졌으며, 쥐의 간당원 함량도 증가된 사실을 알 수 있으며 이로서 본 발명의 건강보조식품은 항피로작용이 있음이 입증된다.As a result of administering 0, 0.17, 0.33, 1.00g / kgbw.day of the dietary supplement of the present invention to the rat continuously for 30 days, the swimming time of the rat was significantly extended and the serum urea nitrogen level was low during the exercise of the rat. In addition, it can be seen that the rat glycoside content is increased, and thus the health supplement of the present invention has an anti-fatigue effect.

본 발명은 700㎎단위의 1캅셀을 1일 2-3번씩 계속 복용하면 영양섭취에서 부족한 미량의 항피로 유효성분을 섭취하게 되어 동일조건에서 피로가 덜오는 항피로작용이 있고 따라서 피로로 인하여 오는 여러가지 질병을 예방하고 건강을 유지할 수 있다.In the present invention, when one capsule of 700mg unit is continuously taken 2-3 times a day, the active ingredient is consumed with a small amount of anti-fatigue lacking in nutritional intake, and there is an anti-fatigue effect under the same conditions, and thus comes from fatigue. You can prevent and keep healthy.

Claims (1)

인삼엑기스 (Ginseng saponin 80mg/g totale solid 60%) 160㎎, 비타민A 분말(Retinol 50%) 15㎍, 비타민 B1 (Thiamine HCl) 1.2㎎,비타민 B2 (Riboflavin) 0.05㎎,비타민 B6 (Pyridoxine HCl) 0.4㎎, 비타민 C (Ascorbic Acid) 18.2㎎,비타민 E 0.27㎎, 니코틴아미드 (Nicotinamide) 4.00㎎,칼슘판토티내이트(Calcium Pantothenate) 10.00㎎,마그네슘옥사이드(Magnesium Oxide) 15.00㎎, 진옥사이드 (Zine Oxide) 5.00㎎, 훼로스랙태이트(Ferrous Lactate) 15.00㎎,골분(Bone meal) 34.00㎎, 밀납(Bee Wax) 28.00㎎,팜 오일(Palm Oil) 28.4㎎,대두유 (Bean Oil) 301.㎎,레시틴(Lecithin) 10.5㎎, 을 균일하게 배합하여 700㎎단위를 1캅셀로 밀봉하여 1일 2-3회복 용하게 된 것을 특징으로 하는 항피로용 건강보조식품.Ginseng extract (Ginseng saponin 80mg / g totale solid 60%) 160mg, Vitamin A powder (Retinol 50%) 15㎍, Vitamin B1 (Thiamine HCl) 1.2mg, Vitamin B2 (Riboflavin) 0.05mg, Vitamin B6 (Pyridoxine HCl) 0.4 mg, Vitamin C (Ascorbic Acid) 18.2 mg, Vitamin E 0.27 mg, Nicotinamide 4.00 mg, Calcium Pantothenate 10.00 mg, Magnesium Oxide 15.00 mg, Zine Oxide) 5.00mg, Ferrous Lactate 15.00mg, Bone meal 34.00mg, Bee Wax 28.00mg, Palm Oil 28.4mg, Soybean Oil 301.mg , Lecithin (lecithin) 10.5mg, uniformly formulated 700mg unit was sealed with one capsule to be used 2-3 times a day for anti-fatigue health supplements.
KR1019990056435A 1999-12-10 1999-12-10 Health augmentation food for the anti fatigue KR20010055274A (en)

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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030030883A (en) * 2001-10-12 2003-04-18 에스에스 세야쿠 가부시키 가이샤 Pharmaceutical composition for recovering from fatigue
KR20040045146A (en) * 2002-11-22 2004-06-01 (주) 내츄로에이스 the natural medicines for the removing hangover and its healthy foods
KR100439202B1 (en) * 2001-09-29 2004-07-07 주식회사 한국인삼공사 Ginseng food for strengthening study efficacy and the preparing method
EP2172203A1 (en) * 2008-09-17 2010-04-07 Giuliani S.P.A. Pharmaceutical composition for the treatment of gastrointestinal irritation disorders
CN103478727A (en) * 2013-08-23 2014-01-01 南通华兴石油仪器有限公司 Food additive
CN103798753A (en) * 2012-11-07 2014-05-21 苏州市洋海电子有限公司 Health product containing American ginseng extract
CN104522461A (en) * 2014-12-04 2015-04-22 黄艳红 Glossy ganoderma peptide rhizoma polygonati polysaccharide and preparation technology thereof
CN104543666A (en) * 2014-12-04 2015-04-29 徐立华 Composite polysaccharide heath food with anti-radiation function and preparation process of composite polysaccharide heath food
CN104738636A (en) * 2015-04-19 2015-07-01 通化青山实业集团有限公司 Health oral liquid of fermented red ginseng
RU2738644C2 (en) * 2019-03-18 2020-12-15 Юрий Александрович Захаров Agent for reducing biological age

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KR880003574A (en) * 1986-09-23 1988-05-28 홍병규 Manufacturing method of soft capsule containing ginseng softening extract
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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100439202B1 (en) * 2001-09-29 2004-07-07 주식회사 한국인삼공사 Ginseng food for strengthening study efficacy and the preparing method
KR20030030883A (en) * 2001-10-12 2003-04-18 에스에스 세야쿠 가부시키 가이샤 Pharmaceutical composition for recovering from fatigue
KR20040045146A (en) * 2002-11-22 2004-06-01 (주) 내츄로에이스 the natural medicines for the removing hangover and its healthy foods
EP2172203A1 (en) * 2008-09-17 2010-04-07 Giuliani S.P.A. Pharmaceutical composition for the treatment of gastrointestinal irritation disorders
CN103798753A (en) * 2012-11-07 2014-05-21 苏州市洋海电子有限公司 Health product containing American ginseng extract
CN103478727A (en) * 2013-08-23 2014-01-01 南通华兴石油仪器有限公司 Food additive
CN104522461A (en) * 2014-12-04 2015-04-22 黄艳红 Glossy ganoderma peptide rhizoma polygonati polysaccharide and preparation technology thereof
CN104543666A (en) * 2014-12-04 2015-04-29 徐立华 Composite polysaccharide heath food with anti-radiation function and preparation process of composite polysaccharide heath food
CN104738636A (en) * 2015-04-19 2015-07-01 通化青山实业集团有限公司 Health oral liquid of fermented red ginseng
RU2738644C2 (en) * 2019-03-18 2020-12-15 Юрий Александрович Захаров Agent for reducing biological age

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