KR102625016B1 - Upcycling functional cosmetic composition comprising the flower extract of Prunus persica as an active ingredient - Google Patents
Upcycling functional cosmetic composition comprising the flower extract of Prunus persica as an active ingredient Download PDFInfo
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- KR102625016B1 KR102625016B1 KR1020230093836A KR20230093836A KR102625016B1 KR 102625016 B1 KR102625016 B1 KR 102625016B1 KR 1020230093836 A KR1020230093836 A KR 1020230093836A KR 20230093836 A KR20230093836 A KR 20230093836A KR 102625016 B1 KR102625016 B1 KR 102625016B1
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- extract
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- peach
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- 240000005809 Prunus persica Species 0.000 title description 8
- 235000011446 Amygdalus persica Nutrition 0.000 title description 2
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Classifications
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9722—Chlorophycota or Chlorophyta [green algae], e.g. Chlorella
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9767—Pinaceae [Pine family], e.g. pine or cedar
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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- A—HUMAN NECESSITIES
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- A61Q19/00—Preparations for care of the skin
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- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
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Abstract
본 발명은 복사나무꽃 추출물을 유효성분으로 포함하는 업사이클링 기능성 화장료 조성물에 관한 것이다. 구체적으로, 버려지는 복사나무의 꽃을 이용하여 추출물을 제조하였고, 이를 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물과 혼합하여 함께 사용하는 경우 항산화 효과가 현저히 증가함을 확인하였다. 또한, 상기 항산화 효과를 나타내는 혼합물을 이용하여 선크림을 제조하여 미백 및 자외선차단 기능성 테스트를 통해 화장료 조성물로 사용될 수 있음을 확인하여 본 발명을 완성하였다. 본 발명의 주요성분인 복사나무꽃 추출물은 지속가능한 환경을 위해 떨어진 복사나무의 꽃만을 이용하여 제조된 것으로 환경 보호, 자원 절약, 개성 있고 차별화된 제품 제공, 경제적 가치 창출 및 지속 가능한 소비 문화 확산과 같은 긍정적인 효과를 줄 수 있다.The present invention relates to an upcycling functional cosmetic composition containing prickly pear flower extract as an active ingredient. Specifically, an extract was prepared using discarded peach tree flowers, and it was confirmed that the antioxidant effect significantly increased when mixed with peach extract, French coastal pine bark extract, Ecklonia cava extract, and Lettuce extract. In addition, the present invention was completed by manufacturing a sunscreen using the mixture showing the antioxidant effect and confirming that it can be used as a cosmetic composition through a whitening and UV protection functional test. The peach tree flower extract, the main ingredient of the present invention, is manufactured using only fallen peach tree flowers for a sustainable environment, and is designed to protect the environment, save resources, provide unique and differentiated products, create economic value, and spread a sustainable consumption culture. It can have the same positive effect.
Description
본 발명은 복사나무꽃 추출물을 유효성분으로 포함하는 업사이클링 기능성 화장료 조성물에 관한 것이다.The present invention relates to an upcycling functional cosmetic composition containing prickly pear flower extract as an active ingredient.
업사이클링(Upcycling)은 재활용보다 더 높은 가치를 창출하는 개념으로, 기존의 폐기물을 창의적으로 활용하여 새로운 소재로 만들어내는 것을 말한다. 장점으로는 환경 보호, 자원 절약, 개성 있고 차별화된 제품 제공, 경제적 가치 창출, 지속 가능한 소비 문화 확산 등이 있다.Upcycling is a concept that creates higher value than recycling, and refers to creative use of existing waste to create new materials. Advantages include protecting the environment, saving resources, providing unique and differentiated products, creating economic value, and spreading a sustainable consumption culture.
한편, 복사나무(Prunus persica)는 장미과 벚나무속에 속하며, 원산지는 중국 화북의 산시성과 간쑤성의 해발 600 ~ 2,000m 고원 지대이다. 복사나무는 복숭아나무라고도 부르고, 갈잎 작은키 나무이며, 대한민국에서 사과나무, 감나무, 귤나무, 포도나무에 이어 많이 기르는 과일나무이기도 하다. 복사나무의 높이는 약 4.5 내지 7.5m에 이르고 잎은 긴 피침형으로 끝이 뾰족하며 가장자리에 톱니가 있다. 초봄에 잎보다 먼저 피는 꽃은 연분홍 빛이고 묵은 가지에서 피며, 열매는 4 내지 5월에 익는다. 과육은 통조림, 잼, 말린 복숭아 등 다양하게 사용되고, 씨는 도인(桃仁)이라 부르며 약재로 쓰인다. 하지만 복사나무의 꽃은 그 쓰임새가 없어 모두 버려지는 현실이다.Meanwhile, the prickly peach tree ( Prunus persica ) belongs to the Rosaceae genus and its origin is the highlands of Shaanxi and Gansu provinces in North China, at an altitude of 600 to 2,000 m. The peach tree, also called the peach tree, is a short-growing tree with split leaves, and is also the most widely grown fruit tree in Korea, following apple trees, persimmon trees, tangerine trees, and grape trees. The height of the peach tree reaches about 4.5 to 7.5 m, and the leaves are long lanceolate with pointed ends and serrated edges. The flowers that bloom before the leaves in early spring are light pink and bloom on old branches, and the fruits ripen in April to May. The pulp is used in various ways, such as canned food, jam, and dried peaches, and the seeds are called doin (桃仁) and are used as medicine. However, the reality is that the flowers of the peach tree are discarded because they have no use.
따라서, 본 발명에서는 버려지는 복사나무의 꽃을 이용하여 추출물을 제조하였고, 이를 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물과 혼합하여 함께 사용하는 경우 항산화 효과가 현저히 증가함을 확인하였으며, 상기 항산화 효과를 내는 혼합물은 미백 및 자외선 차단 효과를 가짐을 입증하여 화장품의 재료로 사용할 수 있음을 확인하여 본 발명을 완성하였다.Therefore, in the present invention, an extract was prepared using discarded peach tree flowers, and it was confirmed that the antioxidant effect significantly increased when mixed with peach extract, French coastal pine bark extract, Ecklonia cava extract, and Lettuce extract. The present invention was completed by confirming that the mixture producing the antioxidant effect can be used as a cosmetic material by proving that it has whitening and ultraviolet ray blocking effects.
상기 문제점을 해결하기 본 발명의 일 과제는 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물로 이루어진 혼합물을 유효성분으로 포함하는 항산화 조성물을 제공하는 데 있다.One object of the present invention to solve the above problems is to provide an antioxidant composition containing as an active ingredient a mixture of prickly peach blossom extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, and leaf lettuce extract.
또한 본 발명의 일 과제는 상기 항산화 조성물을 이용하여 제조된 미백 및 자외선차단 기능이 강화된 화장료 조성물을 제공하는 데 있다.Another object of the present invention is to provide a cosmetic composition with enhanced whitening and UV protection functions prepared using the antioxidant composition.
상기와 같은 목적을 달성하기 위해, 본 발명은 복사나무꽃 추출물, 복숭아 추출물 및 프랑스해안송껍질 추출물로 이루어진 혼합물을 유효성분으로 포함하는 항산화용 화장료 조성물을 제공한다.In order to achieve the above object, the present invention provides an antioxidant cosmetic composition comprising as an active ingredient a mixture of peach tree flower extract, peach extract, and French coastal pine bark extract.
본 발명의 일 실시예에 있어서, 상기 "혼합물"은 복사나무꽃 추출물, 복숭아 추출물 및 프랑스해안송껍질 추출물이 0.5~4 : 0.5~3 : 0.5~2의 중량비로 혼합되는 것일 수 있으나 이에 한정되는 것은 아니다.In one embodiment of the present invention, the "mixture" may be a mixture of peach tree flower extract, peach extract, and French coastal pine bark extract at a weight ratio of 0.5 to 4: 0.5 to 3: 0.5 to 2, but is limited thereto. That is not the case.
본 발명의 일 실시예에 있어서, 상기 "조성물"은 감태 추출물 및 납작파래 추출물을 더 포함하는 것이며, 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물이 0.5~7 : 0.5~3 : 0.5~2 : 0.5~2 : 0.5~2의 중량비로 혼합되는 것일 수 있으나 이에 한정되는 것은 아니다.In one embodiment of the present invention, the "composition" further includes Ecklonia cava extract and Flat seaweed extract, and the content of prickly peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, and Flat seaweed extract is 0.5 to 7. : 0.5~3 : 0.5~2 : 0.5~2 : It may be mixed at a weight ratio of 0.5~2, but is not limited to this.
본 발명의 일 실시예에 있어서, 상기 "조성물"은 선크림, 스킨로션, 스킨소프너, 스킨토너, 아스트린젠트, 로션, 밀크로션, 모이스쳐 로션, 영양로션, 맛사지크림, 영양크림, 모이스처크림, 핸드크림, 파운데이션, 에센스, 영양에센스, 클렌징, 팩, 비누, 바디로션 및 바디클린저로 구성된 제형에서 선택된 하나 이상의 제형인 것일 수 있으나 이에 한정되는 것은 아니다.In one embodiment of the present invention, the "composition" includes sunscreen, skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, It may be one or more formulations selected from formulations consisting of foundation, essence, nutritional essence, cleansing, pack, soap, body lotion, and body cleanser, but is not limited thereto.
본 발명의 일 실시예에 있어서, 상기 "조성물"은 징크옥사이드(Zinc Oxide), 사이클로헥사실록세인(Cyclohexasiloxane), 부틸옥틸살리실레이트(Butyloctyl Salicylate), 프로판다이올(Propanediol), 프로필헵틸카프릴레이트(Propylheptyl Caprylate), 아이소도데케인(Isododecane), 카프릴릴메티콘(Caprylyl Methicone), 폴리글리세릴-3폴리다이메틸실록시에틸다이메티콘(Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone), 소듐하이알루로네이트(Sodium Hyaluronate), 다이스테아다이모늄헥토라이트(Disteardimonium Hectorite), 마그네슘설페이트(Magnesium Sulfate), 트라이에톡시카프릴릴실레인(Triethoxycaprylylsilane), 메틸메타크릴레이트크로스폴리머(Methyl Methacrylate Crosspolymer), 폴리글리세릴-2다이폴리하이드록시스테아레이트(Polyglyceryl-2 Dipolyhydroxystearate), 라우릴폴리글리세릴-3폴리다이메틸실록시에틸다이메티콘(Lauryl Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone), 합성플루오르플로고파이트(Synthetic Fluorphlogopite), 글리세릴카프릴레이트(Glyceryl Caprylate), 다이카프릴릴카보네이트(Dicaprylyl Carbonate), 마이카(Mica), 토코페롤(Tocopherol), 1,2-헥산다이올(1,2-Hexanediol), 항료(Fragrance), 카프릴릴글라이콜(Caprylyl Glycol), 에틸헥실글리세린(Ethylhexylglycerin), 황색산화철(Iron Oxide Yellow, Hydrated Ferric Oxide), 적색산화철(Iron Oxide Red, Ferric Oxide), 흑색산화철(Iron Oxide Black, Ferrous-Ferric Oxide), 부틸렌글라이콜(Butylene Glycol) 및 정제수를 더 포함하는 것일 수 있으나 이에 한정되는 것은 아니다.In one embodiment of the present invention, the "composition" includes zinc oxide, cyclohexasiloxane, butyloctyl salicylate, propanediol, and propylheptylcapryl. Propylheptyl Caprylate, Isododecane, Caprylyl Methicone, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Sodium Hyaluronate ( Sodium Hyaluronate, Disteardimonium Hectorite, Magnesium Sulfate, Triethoxycaprylylsilane, Methyl Methacrylate Crosspolymer, polyglyceryl -2 Dipolyhydroxystearate, Lauryl Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Synthetic Fluorphlogopite, Glyceryl Caprylate, Dicaprylyl Carbonate, Mica, Tocopherol, 1,2-Hexanediol, Fragrance, Carbonate Caprylyl Glycol, Ethylhexylglycerin, Iron Oxide Yellow, Hydrated Ferric Oxide, Iron Oxide Red, Ferric Oxide, Iron Oxide Black, Ferrous-Ferric Oxide ), butylene glycol (Butylene Glycol) and purified water, but is not limited thereto.
본 발명은 복사나무꽃 추출물을 유효성분으로 포함하는 업사이클링 기능성 화장료 조성물에 관한 것으로, 버려지는 복사나무의 꽃을 이용하여 추출물을 제조하였고, 이를 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물과 혼합하여 함께 사용하는 경우 항산화 효과가 현저히 증가함을 확인하였다. 또한, 상기 항산화 효과를 나타내는 혼합물을 이용하여 선크림을 제조하는 경우 미백 및 자외선차단 기능성이 뛰어남을 확인하여 본 발명을 완성하였다. 본 발명의 주요성분인 복사나무꽃 추출물은 지속가능한 환경을 위해 떨어진 복사나무의 꽃만을 이용하여 제조된 것으로 환경 보호, 자원 절약, 개성 있고 차별화된 제품 제공, 경제적 가치 창출, 지속 가능한 소비 문화 확산과 같은 긍정적인 효과를 가질 수 있다.The present invention relates to an upcycling functional cosmetic composition containing peach tree flower extract as an active ingredient. The extract was prepared using discarded peach tree flowers, and the extract was prepared using peach extract, French coastal pine bark extract, Ecklonia cava extract, and peach extract. It was confirmed that the antioxidant effect significantly increased when mixed with seaweed extract and used together. In addition, the present invention was completed by confirming that when sunscreen was prepared using the mixture showing the antioxidant effect, it had excellent whitening and UV blocking functionality. The peach tree flower extract, the main ingredient of the present invention, is manufactured using only fallen peach tree flowers for a sustainable environment, and is designed to protect the environment, save resources, provide unique and differentiated products, create economic value, and spread a sustainable consumption culture. It can have the same positive effect.
도 1은 본 발명의 일 실시예에 있어서, 본 발명의 복사나무꽃 추출물, 복숭아 추출물 및 프랑스해안송껍질 추출물을 이용하여 제조된 선크림을 나타낸 도이다.
도 2는 본 발명의 일 실시예에 있어서, 본 발명의 복사나무꽃 추출물, 복숭아 추출물 및 프랑스해안송껍질 추출물을 이용하여 제조된 선크림의 입자 크기 분포도를 나타낸 것이다.Figure 1 is a diagram showing a sunscreen prepared using the peach tree flower extract, peach extract, and French coastal pine bark extract of the present invention in one embodiment of the present invention.
Figure 2 shows the particle size distribution of a sunscreen prepared using the peach tree flower extract, peach extract, and French coastal pine bark extract of the present invention in one embodiment of the present invention.
이하, 첨부된 도면을 참조하여 본 발명의 구현예로 본 발명을 상세히 설명하기로 한다. 다만, 하기 구현 예는 본 발명에 대한 예시로 제시되는 것으로, 당업자에게 주지 저명한 기술 또는 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우에는 그 상세한 설명을 생략할 수 있고, 이에 의해 본 발명이 제한되지는 않는다. 본 발명은 후술하는 특허 청구범위의 기재 및 그로부터 해석되는 균등 범주 내에서 다양한 변형 및 응용이 가능하다.Hereinafter, the present invention will be described in detail through embodiments of the present invention with reference to the attached drawings. However, the following implementation examples are provided as examples of the present invention, and if it is judged that a detailed description of a technology or configuration well known to those skilled in the art may unnecessarily obscure the gist of the present invention, the detailed description may be omitted. , the present invention is not limited thereby. The present invention is capable of various modifications and applications within the description of the patent claims described below and the scope of equivalents interpreted therefrom.
또한, 본 명세서에서 사용되는 용어(Terminology)들은 본 발명의 바람직한 실시 예를 적절히 표현하기 위해 사용된 용어들로서, 이는 사용자, 운용자의 의도 또는 본 발명이 속하는 분야의 관례 등에 따라 달라질 수 있다. 따라서 본 용어들에 대한 정의는 본 명세서 전반에 걸친 내용을 토대로 내려져야 할 것이다. 명세서 전체에서, 어떤 부분이 어떤 구성요소를 "포함"한다고 할 때, 이는 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라 다른 구성 요소를 더 포함할 수 있는 것을 의미한다.In addition, terminology used in this specification is a term used to appropriately express preferred embodiments of the present invention, and may vary depending on the intention of the user or operator or the customs of the field to which the present invention belongs. Therefore, definitions of these terms should be made based on the content throughout this specification. Throughout the specification, when a part is said to “include” a certain element, this means that it may further include other elements rather than excluding other elements, unless specifically stated to the contrary.
본 명세서 전체에 걸쳐, 특정 물질의 농도를 나타내기 위하여 사용되는 '%'는 별도의 언급이 없는 경우, 고체/고체는 (w/w) %, 고체/액체는 (w/v) %, 그리고 액체/액체는 (v/v) %이다.Throughout this specification, '%' used to indicate the concentration of a specific substance means (w/w) % for solid/solid, (w/v) % for solid/liquid, and Liquid/liquid is (v/v) %.
일 측면에서, 본 발명은 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물로 이루어진 혼합물을 유효성분으로 포함하는 항산화용 화장료 조성물일 수 있다.In one aspect, the present invention may be an antioxidant cosmetic composition containing a mixture of prickly peach blossom extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, and sea lettuce extract as active ingredients.
본 발명의 화장료 조성물은 항산화 효과를 통해 피부의 노화 방지 등에 다양하게 이용될 수 있고, 또한 본 발명의 혼합물은 추가적으로 미백 및 자외선차단 기능을 가진다. 본 조성물을 첨가할 수 있는 제품으로는, 예를 들어, 선크림을 포함한 각종 크림, 스킨, 로션, 에센스 등과 같은 화장품류와 클렌징폼, 클렌징로션, 클렌징크림, 샴푸, 린스, 세안제, 비누, 트리트먼트, 팩, 미용액 등이 있다.The cosmetic composition of the present invention can be used in various ways to prevent skin aging through its antioxidant effect, and the mixture of the present invention additionally has whitening and ultraviolet ray blocking functions. Products to which this composition can be added include, for example, cosmetics such as sunscreen and various creams, skins, lotions, essences, cleansing foam, cleansing lotion, cleansing cream, shampoo, rinse, face wash, soap, and treatment. , packs, beauty essence, etc.
본 발명의 화장료는 수용성 비타민, 유용성 비타민, 고분자 펩티드, 고분자 다당, 스핑고 지질 및 해초 추출물로 이루어진 군에서 선택된 조성물을 포함한다.The cosmetic of the present invention includes a composition selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, high molecular weight peptides, high molecular weight polysaccharides, sphingolipids, and seaweed extracts.
수용성 비타민으로서는 화장품에 배합 가능한 것이라면 어떠한 것이라도 되지만, 바람직하게는 비타민 B1, 비타민 B2, 비타민 B6, 피리독신, 염산피리독신, 비타민 B12, 판토텐산, 니코틴산, 니코틴산아미드, 엽산, 비타민 C, 비타민 H 등을 들 수 있으며, 그들의 염(티아민염산염, 아스코르빈산나트륨염 등)이나 유도체(아스코르빈산-2-인산나트륨염, 아스코르빈산-2-인산마그네슘염 등)도 본 발명에서 사용할 수 있는 수용성 비타민에 포함된다. 수용성 비타민은 미생물 변환법, 미생물의 배양물로부터의 정제법, 효소법 또는 화학 합성법 등의 통상의 방법에 의해 수득할 수 있다.Water-soluble vitamins may be any that can be mixed into cosmetics, but preferably include vitamin B1, vitamin B2, vitamin B6, pyridoxine, pyridoxine hydrochloride, vitamin B12, pantothenic acid, nicotinic acid, nicotinic acid amide, folic acid, vitamin C, and vitamin H. and their salts (thiamine hydrochloride, sodium ascorbate, etc.) or derivatives (sodium ascorbic acid-2-phosphate, magnesium ascorbic acid-2-phosphate, etc.) are also water-soluble vitamins that can be used in the present invention. Included. Water-soluble vitamins can be obtained by conventional methods such as microbial transformation, purification from microbial cultures, enzymatic methods, or chemical synthesis.
유용성 비타민으로서는 화장품에 배합 가능한 것이라면 어떠한 것이라도 되지만, 바람직하게는 비타민 A, 카로틴, 비타민 D2, 비타민 D3, 비타민 E(d1-알파 토코페롤, d-알파 토코페롤, d-알파 토코페롤) 등을 들 수 있으며, 그들의 유도체(팔미틴산아스코르빈, 스테아르산아스코르빈, 디팔미틴산아스코르빈, 아세트산dl-알파 토코페롤, 니코틴산dl-알파 토코페롤비타민 E, DL-판토테닐알코올, D-판토테닐알코올, 판토테닐에틸에테르 등) 등도 본 발명에서 사용되는 유용성 비타민에 포함된다. 유용성 비타민은 미생물 변환법, 미생물의 배양물로부터의 정제법, 효소 또는 화학 합성법 등의 통상의 방법에 의해 취득할 수 있다.Oil-soluble vitamins may be any that can be mixed into cosmetics, but preferably include vitamin A, carotene, vitamin D2, vitamin D3, vitamin E (d1-alpha tocopherol, d-alpha tocopherol, d-alpha tocopherol), etc. , their derivatives (ascorbic palmitate, ascorbic stearate, ascorbic acid dipalmitate, dl-alpha tocopherol acetate, dl-alpha tocopherol nicotinic acid, vitamin E, DL-pantothenyl alcohol, D-pantothenyl alcohol, pantothenyl ethyl ether, etc.) are also included in the oil-soluble vitamins used in the present invention. Oil-soluble vitamins can be obtained by conventional methods such as microbial transformation, purification from microbial cultures, enzymatic or chemical synthesis.
고분자 펩티드로서는 화장품에 배합 가능한 것이라면 어떠한 것이라도 되지만, 바람직하게는 콜라겐, 가수 분해 콜라겐, 젤라틴, 엘라스틴, 가수 분해 엘라스틴, 케라틴 등을 들 수 있다. 고분자 펩티드는 미생물의 배양액으로부터의 정제법, 효소법 또는 화학 합성법 등의 통상의 방법에 의해 정제 취득할 수 있으며, 또는 통상 돼지나 소 등의 진피, 누에의 견섬유 등의 천연물로부터 정제하여 사용할 수 있다.The polymer peptide may be any peptide that can be blended into cosmetics, but preferably includes collagen, hydrolyzed collagen, gelatin, elastin, hydrolyzed elastin, and keratin. High molecular weight peptides can be purified and obtained by conventional methods such as purification from microbial culture media, enzymatic methods, or chemical synthesis, or they can usually be purified and used from natural products such as dermis of pigs or cows or silk fiber of silkworms.
고분자 다당으로서는 화장품에 배합 가능한 것이라면 어떠한 것이라도 되지만, 바람직하게는 히드록시에틸셀룰로오스, 크산탄검, 히알루론산나트륨, 콘드로이틴 황산 또는 그 염(나트륨염 등) 등을 들 수 있다. 예를 들어, 콘드로이틴 황산 또는 그 염 등은 통상 포유 동물이나 어류로부터 정제하여 사용할 수 있다.The polymer polysaccharide may be any one that can be blended into cosmetics, but preferably includes hydroxyethyl cellulose, xanthan gum, sodium hyaluronate, chondroitin sulfate or its salts (sodium salt, etc.). For example, chondroitin sulfate or its salt can usually be purified and used from mammals or fish.
스핑고 지질로서는 화장품에 배합 가능한 것이라면 어떠한 것이라도 되지만, 바람직하게는 세라미드, 피토스핑고신, 스핑고당지질 등을 들 수 있다. 스핑고 지질은 통상 포유류, 어류, 패류, 효모 또는 식물 등으로부터 통상의 방법에 의해 정제하거나 화학 합성법에 의해 취득할 수 있다.The sphingolipid may be any one that can be blended into cosmetics, but preferred examples include ceramide, phytosphingosine, and sphingolipid. Sphingolipids can usually be purified by conventional methods from mammals, fish, shellfish, yeast, or plants, or obtained by chemical synthesis.
해초 추출물로는 화장품에 배합 가능한 것이라면 어떠한 것이라도 되지만, 바람직하게는 갈조 엑기스, 홍조 엑기스, 녹조 엑기스 등을 들 수 있으며, 또, 이들의 해초 엑기스로부터 정제된 칼라기난, 아르긴산, 아르긴산나트륨, 아르긴산칼륨 등도 본 발명에서 사용되는 해초 엑기스에 포함된다. 해초 엑기스는 해초로부터 통상의 방법에 의해 정제하여 취득할 수 있다.The seaweed extract may be any one that can be blended into cosmetics, but preferably includes brown algae extract, red algae extract, green algae extract, etc. Also, calrageenan, arginic acid, sodium alginate, etc. purified from these seaweed extracts. Potassium arginate and the like are also included in the seaweed extract used in the present invention. Seaweed extract can be obtained by purifying seaweed by a conventional method.
본 발명의 화장료에는 상기 필수 성분과 더불어 필요에 따라 통상 화장료에 배합되는 다른 성분을 배합해도 된다. 이외에 첨가해도 되는 배합 성분으로서는 유지성분, 보습제, 에몰리엔트제, 계면 활성제, 유기 및 무기안료, 유기 분체, 자외선 흡수제, 방부제, 살균제, 산화 방지제, 식물 추출물, pH 조정제, 알콜, 색소, 향료, 혈행 촉진제, 냉감제, 제한(制汗)제, 정제수 등을 들 수 있다. 유지 성분으로서는 에스테르계 유지, 탄화수소계 유지, 실리콘계 유지, 불소계 유지, 동물 유지, 식물 유지 등을 들 수 있다.In addition to the above-mentioned essential ingredients, the cosmetic of the present invention may contain other ingredients usually blended in cosmetics as needed. Other ingredients that may be added include oils and fats, moisturizers, emollients, surfactants, organic and inorganic pigments, organic powders, ultraviolet absorbers, preservatives, disinfectants, antioxidants, plant extracts, pH adjusters, alcohol, colorants, fragrances, Examples include blood circulation promoters, cooling agents, antiperspirants, and purified water. Examples of oil and fat components include ester-based fats and oils, hydrocarbon-based fats and oils, silicone-based fats and oils, fluorine-based fats and oils, animal fats and oils, and vegetable fats and oils.
에스테르계 유지로서는 트리2-에틸헥산산글리세릴, 2-에틸헥산산세틸, 미리스틴산이소프로필, 미리스틴산 부틸, 팔미틴산이소프로필, 스테아르산에틸, 팔미틴산옥틸, 이소스테아르산이소세틸, 스테아르산부틸, 리놀레산 에틸,리놀레산이소프로필, 올레인산에틸, 미리스틴산이소세틸, 미리스틴산이소스테아릴, 팔미틴산이소스테아릴, 미리스틴산옥틸도데실, 이소스테아르산이소세틸, 세바신산디에틸, 아디핀산디이소프로필, 네오펜탄산이소알킬, 트리(카프릴, 카프린산)글리세릴, 트리2-에틸헥산산트리메틸롤프로판, 트리이소스테아르산 트리메틸롤프로판, 테트라2-에틸헥산산펜타엘리슬리톨, 카프릴산세틸, 라우린산데실, 라우린산헥실, 미리스틴산데실, 미리스틴산미리스틸, 미리스틴산세틸, 스테아르산스테아릴, 올레인산데실, 리시노올레인산세틸, 라우린산이소스테아릴, 미리스틴산이소트리데실, 팔미틴산이소세틸, 스테아르산옥틸, 스테아르산 이소세틸, 올레인산이소데실, 올레인산옥틸도데실, 리놀레산옥틸도데실, 이소스테아르산이소프로필, 2-에틸헥산산세토스테아릴, 2-에틸헥산산스테아릴, 이소스테아르산헥실, 디옥탄산에틸렌글리콜, 디올레인산에틸렌글리콜, 디카프린산프로필렌글리콜, 디(카프릴, 카프린산)프로필렌글리콜, 디카프릴산프로필렌글리콜, 디카프린산네오펜 틸글리콜, 디옥탄산네오펜틸글리콜, 트리카프릴산글리세릴, 트리운데실산글리세릴, 트리이소팔미틴산글리세릴, 트리이소스테아르산글리세릴, 네오펜탄산옥틸도데실, 옥탄산이소스테아릴, 이소노난산옥틸, 네오데칸산헥실데실, 네오데칸산옥틸도데실, 이소스테아르산이소세틸, 이소스테아르산이소스테아릴, 이소스테아르산옥틸데실, 폴리글리세린올레인산에스테르, 폴리글리세린이소스테아르산에스테르, 시트르산트리이소세틸, 시트르산트리이소알킬, 시트르산트리이소옥틸, 락트산라우릴, 락트산미리스틸, 락트산세틸, 락트산옥틸데실, 시트르산트리에틸, 시트르산아세틸트리에틸, 시트르산아세틸트리부틸, 시트르산트리옥틸, 말산디이소스테아릴, 히드록시스테아르산 2-에틸헥실, 숙신산디2-에틸헥실, 아디핀산디이소부틸, 세바신산디이소프로필, 세바신산디옥틸, 스테아르산콜레스테릴, 이소스테아르산콜레스테릴, 히드록시스테아르산콜레스테릴, 올레인산콜레스테릴, 올레인 산디히드로콜레스테릴, 이소스테아르산피트스테릴, 올레인산피트스테릴, 12-스테알로일히드록시스테아르산이소세틸, 12-스테알로일히드록시스테아르산스테아릴, 12-스테알로일히드록시스테아르산이소스테아릴 등의 에스테르 계 등을 들 수 있다. Ester-based oils include glyceryl tri2-ethylhexanoate, cetyl 2-ethylhexanoate, isopropyl myristate, butyl myristate, isopropyl palmitate, ethyl stearate, octyl palmitate, isocetyl isostearate, and stearic acid. Butyl, ethyl linoleate, isopropyl linoleate, ethyl oleate, isocetyl myristate, isostearyl myristate, isostearyl palmitate, octyldodecyl myristate, isocetyl isostearate, diethyl sebacate, adipine. Diisopropyl acid, isoalkyl neopentanoate, tri(caprylic, capric acid)glyceryl, trimethylolpropane tri2-ethylhexanoate, trimethylolpropane triisostearate, pentaelislitol tetra2-ethylhexanoate , cetyl caprylate, decyl laurate, hexyl laurate, decyl myristate, myristyl myristate, cetyl myristate, stearyl stearate, decyl oleate, cetyl ricinooleate, isostear laurate. Reyl, isotridecyl myristate, isocetyl palmitate, octyl stearate, isocetyl stearate, isodecyl oleate, octyldodecyl oleate, octyldodecyl linoleate, isopropyl isostearate, cetoester 2-ethylhexanoate Aryl, 2-ethylhexanoate stearyl, hexyl isostearate, ethylene glycol dioctanate, ethylene glycol dioleate, propylene glycol dicapric acid, di(capryl, capric acid) propylene glycol, propylene glycol dicaprylate, dicapric acid Neopentyl glycol prinate, neopentyl glycol dioctanate, glyceryl tricaprylate, glyceryl triundecylate, glyceryl triisopalmitate, glyceryl triisostearate, octyldodecyl neopentanoate, isostear octanoate. Reyl, octyl isononanoate, hexyldecyl neodecanoate, octyldodecyl neodecanoate, isocetyl isostearate, isostearyl isostearate, octyldecyl isostearate, polyglycerol oleic acid ester, polyglycerol isostearic acid ester. , Triisocetyl citrate, Triisoalkyl citrate, Triisooctyl citrate, Lauryl lactate, Myristyl lactate, Cetyl lactate, Octyldecyl lactate, Triethyl citrate, Acetyltriethyl citrate, Acetyltributyl citrate, Trioctyl citrate, Mal. Diisostearyl acid, 2-ethylhexyl hydroxystearate, di2-ethylhexyl succinate, diisobutyl adipate, diisopropyl sebacate, dioctyl sebacate, cholesteryl stearate, cholesteryl isostearate. , cholesteryl hydroxystearate, cholesteryl oleate, dihydrocholesteryl oleate, phytsteryl isostearate, phytsteryl oleate, 12-stealoyl hydroxystearate isocetyl, 12-stealoyl Ester systems such as stearyl monohydroxystearate and isostearyl 12-stealoylhydroxystearate can be mentioned.
탄화 수소계 유지로서는 스쿠알렌, 유동 파라핀, 알파-올레핀올리고머, 이소파라핀, 세레신, 파라핀, 유동 이소파라핀, 폴리부덴, 마이크로크리스탈린왁스, 와셀린 등의 탄화수소계 유지 등을 들 수 있다.Hydrocarbon-based fats and oils include squalene, liquid paraffin, alpha-olefin oligomer, isoparaffin, ceresin, paraffin, liquid isoparaffin, polybudene, microcrystalline wax, and petroleum jelly.
실리콘계 유지로서는 폴리메틸실리콘, 메틸페닐실리콘, 메틸시클로폴리실록산, 옥타메틸폴리실록산, 데카메틸폴리실록산, 도데카메틸시클로실록산, 디메틸실록산 및 메틸세틸옥시실록산 공중합체, 디메틸실록산 및 메틸스테알록시실록산 공중합체, 알킬 변성 실리콘유, 아미노 변성 실리콘유 등을 들 수 있다.Silicone oils include polymethyl silicone, methylphenyl silicone, methylcyclopolysiloxane, octamethylpolysiloxane, decamethylpolysiloxane, dodecamethylcyclosiloxane, dimethylsiloxane and methylcetyloxysiloxane copolymer, dimethylsiloxane and methylstealoxysiloxane copolymer, and alkyl. Modified silicone oil, amino-modified silicone oil, etc. can be mentioned.
불소계 유지로서는 퍼플루오로폴리에테르 등을 들 수 있다.Examples of fluorine-based fats and oils include perfluoropolyether.
동물 또는 식물 유지로서는 아보카도유, 아르몬드유, 올리브유, 참깨유, 쌀겨유, 새플라워유, 대두유, 옥수수유, 유채유, 행인(杏仁)유, 팜핵유, 팜유, 피마자유, 해바라기유, 포도종자유, 면실유, 야자유, 쿠쿠이너트유, 소맥배아유, 쌀 배아유, 시아버터, 월견초유, 마커데이미아너트유, 메도홈유, 난황유, 우지(牛脂), 마유, 밍크유, 오렌지라피유, 호호바유, 캔데리러왁스, 카르나바왁스, 액상 라놀린, 경화피마자유 등의 동물 또는 식물 유지를 들 수 있다.Animal or plant oils include avocado oil, almond oil, olive oil, sesame oil, rice bran oil, birdflower oil, soybean oil, corn oil, rapeseed oil, apricot oil, palm kernel oil, palm oil, castor oil, sunflower oil, and grape seed oil. , cottonseed oil, palm oil, cucumber nut oil, wheat germ oil, rice germ oil, shea butter, walnut colostrum oil, marker damia nut oil, meadow oil, egg yolk oil, beef tallow, horse oil, mink oil, orange rape oil, jojoba oil. , animal or plant oils such as candelier wax, carnaba wax, liquid lanolin, and hydrogenated castor oil.
보습제로서는 수용성 저분자 보습제, 지용성 분자 보습제, 수용성 고분자, 지용성 고분자 등을 들 수 있다.Moisturizers include water-soluble low-molecular-weight moisturizers, oil-soluble molecular moisturizers, water-soluble polymers, and fat-soluble polymers.
수용성 저분자 보습제로서는 세린, 글루타민, 솔비톨, 만니톨, 피롤리돈-카르복실산나트륨, 글리세린, 프로필렌글리콜, 1,3-부틸렌글리콜, 에틸렌글리콜, 폴리에틸렌글리콜B(중합도 n = 2 이상), 폴리프로필렌글리콜 (중합도 n = 2 이상), 폴리글리세린B(중합도 n = 2 이상), 락트산, 락트산염 등을 들 수 있다.Water-soluble low-molecular-weight moisturizers include serine, glutamine, sorbitol, mannitol, sodium pyrrolidone-carboxylate, glycerin, propylene glycol, 1,3-butylene glycol, ethylene glycol, polyethylene glycol B (degree of polymerization n = 2 or more), and polypropylene. Examples include glycol (degree of polymerization n = 2 or more), polyglycerin B (degree of polymerization n = 2 or more), lactic acid, lactate, etc.
지용성 저분자 보습제로서는 콜레스테롤, 콜레스테롤에스테르 등을 들 수 있다.Examples of fat-soluble low-molecular-weight moisturizers include cholesterol and cholesterol esters.
수용성 고분자로서는 카르복시비닐폴리머, 폴리아스파라긴산염, 트라가칸트, 크산탄검, 메틸셀룰로오스, 히드록시메틸셀룰로오스, 히드록시에틸셀룰로오스, 히드록시프로필셀룰로오스, 카르복시메틸셀룰로오스, 수용성키틴, 키토산, 덱스트린 등을 들 수 있다.Water-soluble polymers include carboxyvinyl polymer, polyaspartate, tragacanth, xanthan gum, methylcellulose, hydroxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, carboxymethylcellulose, water-soluble chitin, chitosan, dextrin, etc. You can.
지용성 고분자로서는 폴리비닐피롤리돈 및 에이코센 공중합체, 폴리비닐피롤리돈 및 헥사데센 공중합체, 니트로셀룰로오스, 덱스트린지방산에스테르, 고분자 실리콘 등을 들수 있다. 에몰리엔트제로서는 장쇄아실글루타민산 콜레스테릴에스테르, 히드록시스테아르산콜레스테릴, 12-히드록시스테아르산, 스테아르산, 로진산, 라놀린지방산콜레스테릴에스테르 등을 들 수 있다.Examples of oil-soluble polymers include polyvinylpyrrolidone and eicosene copolymers, polyvinylpyrrolidone and hexadecene copolymers, nitrocellulose, dextrin fatty acid ester, and polymer silicone. Examples of emollients include long-chain acyl glutamic acid cholesteryl ester, hydroxystearic acid cholesteryl, 12-hydroxystearic acid, stearic acid, rosin acid, and lanolin fatty acid cholesteryl ester.
계면 활성제로서는 비이온성 계면 활성제, 음이온성 계면 활성제, 양이온성 계면 활성제, 양성 계면 활성제 등을 들 수 있다.Examples of surfactants include nonionic surfactants, anionic surfactants, cationic surfactants, and amphoteric surfactants.
비이온성 계면 활성제로서는 자기 유화형 모노스테아르산글리세린, 프로필렌글리콜지방산에스테르, 글리세린 지방산에스테르, 폴리글리세린지방산에스테르, 솔비탄지방산에스테르, POE(폴리옥시에틸렌)솔비탄지방산에스테르, POE 솔비트지방산에스테르, POE 글리세린지방산에스테르, POE 알킬에테르, POE 지방산에스테르, POE 경화피마자유, POE 피마자유, POE 및 POP(폴리옥시에틸렌 및 폴리옥시프로필렌) 공중합체, POE 및 POP 알킬에테르, 폴리에테르변성실리콘, 라우린산알카놀아미드, 알킬아민옥시드, 수소첨가대두인지질 등을 들 수 있다.Nonionic surfactants include self-emulsifying glycerin monostearate, propylene glycol fatty acid ester, glycerin fatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester, POE (polyoxyethylene) sorbitan fatty acid ester, POE sorbitan fatty acid ester, POE. Glycerin fatty acid ester, POE alkyl ether, POE fatty acid ester, POE hydrogenated castor oil, POE castor oil, POE and POP (polyoxyethylene and polyoxypropylene) copolymer, POE and POP alkyl ether, polyether modified silicone, lauric acid. Examples include alkanolamide, alkylamine oxide, and hydrogenated soybean phospholipid.
음이온성 계면 활성제로서는 지방산비누, 알파-아실술폰산염, 알킬술폰산염, 알킬알릴술폰산염, 알킬나프탈렌술폰산염, 알킬황산염, POE 알킬에테르황산염, 알킬아미드황산염, 알킬인산염, POE 알킬인산업, 알킬아미드 인산염, 알킬로일알킬타우린염, N-아실아미노산염, POE 알킬에테르카르복실산염, 알킬술포숙신산염, 알킬술포아세트산나트륨, 아실화 가수분해 콜라겐펩티드염, 퍼플루오로알킬인산에스테르 등을 들 수 있다.Anionic surfactants include fatty acid soap, alpha-acyl sulfonate, alkyl sulfonate, alkyl allyl sulfonate, alkyl naphthalene sulfonate, alkyl sulfate, POE alkyl ether sulfate, alkyl amide sulfate, alkyl phosphate, POE alkyl phosphate industry, alkyl amide. Phosphate, alkyloyl alkyl taurine salt, N-acylamino acid salt, POE alkyl ether carboxylate, alkyl sulfosuccinate, sodium alkyl sulfoacetate, acylated hydrolyzed collagen peptide salt, perfluoroalkyl phosphate ester, etc. there is.
양이온성 계면 활성제로서는 염화알킬트리메틸암모늄, 염화스테아릴트리메틸암모늄, 브롬화스테아릴트리메틸암모늄, 염화세토스테아릴트리메틸암모늄, 염화디스테아릴디메틸암모늄, 염화스테아릴디메틸벤질암모늄, 브롬화베헤닐트리메틸암모늄, 염화벤잘코늄, 스테아르산 디에틸아미노에틸아미드, 스테아르산디메틸아미노프로필아 미드, 라놀린 유도체 제 4급 암모늄염 등을 들 수 있다. 양성 계면 활성제로서는 카르복시베타인형, 아미드베타인형, 술포베타인형, 히드록시술포베타인형, 아미드 술포 베타인형, 포스포베타인형, 아미노카르복실산염형, 이미다졸린 유도체형, 아미드아민형 등의 양성 계면 활성제 등을 들 수 있다.Cationic surfactants include alkyltrimethylammonium chloride, stearyltrimethylammonium chloride, stearyltrimethylammonium bromide, cetostearyltrimethylammonium chloride, distearyldimethylammonium chloride, stearyldimethylbenzylammonium chloride, behenyltrimethylammonium bromide, and cationic surfactant. Examples include benzalkonium, diethylaminoethylamide stearate, dimethylaminopropyl stearate, and quaternary ammonium salts of lanolin derivatives. Amphoteric surfactants include carboxy beta type, amide beta type, sulfo beta type, hydroxy sulfo beta type, amide sulfo betaine type, phosphobetain type, aminocarboxylate type, imidazoline derivative type, and amidamine type. Amphoteric surfactants, etc. can be mentioned.
유기 및 무기 안료로서는 규산, 무수규산, 규산마그네슘, 탤크, 세리사이트, 마이카, 카올린, 벵갈라, 클레이, 벤토나이트, 티탄피막운모, 옥시염화비스무트, 산화지르코늄, 산화마그네슘, 산화아연, 산화티탄, 산화알루미늄, 황산칼슘, 황산바륨, 황산마그네슘, 탄산칼슘, 탄산마그네슘, 산화철, 군청, 산화크롬, 수산화크롬, 칼라민 및 이들의 복합체등의 무기 안료; 폴리아미드, 폴리에스테르, 폴리프로필렌, 폴리스티렌, 폴리우레탄, 비닐수지, 요소수지, 페놀수지, 불소수지, 규소수지, 아크릴수지, 멜라민수지, 에폭시수지, 폴리카보네이트 수지, 디비닐벤젠 및 스티렌 공중합체, 실크파우더, 셀룰로오스, CI 피그먼트옐로우, CI 피그먼트오렌지 등의 유기 안료 및 이들의 무기 안료와 유기 안료의 복합 안료 등을 들 수 있다.Organic and inorganic pigments include silicic acid, anhydrous silicic acid, magnesium silicate, talc, sericite, mica, kaolin, bengala, clay, bentonite, titanium-coated mica, bismuth oxychloride, zirconium oxide, magnesium oxide, zinc oxide, titanium oxide, and aluminum oxide. Inorganic pigments such as calcium sulfate, barium sulfate, magnesium sulfate, calcium carbonate, magnesium carbonate, iron oxide, ultramarine blue, chromium oxide, chromium hydroxide, calamine and complexes thereof; Polyamide, polyester, polypropylene, polystyrene, polyurethane, vinyl resin, urea resin, phenolic resin, fluorine resin, silicon resin, acrylic resin, melamine resin, epoxy resin, polycarbonate resin, divinylbenzene and styrene copolymer, Examples include organic pigments such as silk powder, cellulose, CI pigment yellow, and CI pigment orange, and complex pigments of these inorganic pigments and organic pigments.
유기 분체로서는 스테아르산칼슘 등의 금속비누; 세틸린산아연나트륨, 라우릴린산아연, 라우릴린산칼슘 등의 알킬인산금속염; N-라우로일-베타-알라닌칼슘, N-라우로일-베타-알라닌아연, N-라우로일글리신칼슘 등의 아실아미노산 다가금속염; N-라우로일-타우린칼슘, N-팔미토일-타우린칼슘 등의 아미드술폰산 다가금속염; N-엡실론-라우로일-L-리진, N-엡실론-팔미토일리진, N-알파-파리토일올니틴, N-알파-라우로일아르기닌, N-알파-경화우지지방산아실아르기닌 등의 N-아실염기성아미노산; N-라우로일글리실글리신 등의 N-아실폴리펩티드; 알파-아미노카프릴산, 알파-아미노라우린산 등의 알파-아미노지방산; 폴리에틸렌, 폴리프로필렌, 나일론, 폴리메틸메타크릴레이트, 폴리스티렌, 디비닐벤젠 및 스티렌 공중합체, 사불화에틸렌 등을 들 수 있다.Examples of organic powder include metal soap such as calcium stearate; Alkyl phosphate metal salts such as sodium zinc cetilate, zinc laurylate, and calcium laurylate; Acyl amino acid polyvalent metal salts such as N-lauroyl-beta-alanine calcium, N-lauroyl-beta-alanine zinc, and N-lauroyl glycine calcium; Amidesulfonic acid polyvalent metal salts such as N-lauroyl-taurine calcium and N-palmitoyl-taurine calcium; N such as N-epsilon-lauroyl-L-lysine, N-epsilon-palmitoylizine, N-alpha-paritoylolnithine, N-alpha-lauroylarginine, N-alpha-hydrogenated beef tallow fatty acid acylarginine, etc. -Acyl basic amino acid; N-acyl polypeptides such as N-lauroylglycylglycine; Alpha-amino fatty acids such as alpha-aminocaprylic acid and alpha-aminolauric acid; Examples include polyethylene, polypropylene, nylon, polymethyl methacrylate, polystyrene, divinylbenzene and styrene copolymers, and ethylene tetrafluoride.
자외선 흡수제로서는 파라아미노벤조산, 파라아미노벤조산에틸, 파라아미노벤조산아밀, 파라아미노벤조산옥틸, 살리실산에틸렌글리콜, 살리신산페닐, 살리신산옥틸, 살리신산벤질, 살리신산부틸페닐,살리신산호모멘틸, 계피산벤질, 파라메톡시계피산-2-에톡시에틸, 파라메톡시계피산옥틸, 디파라메톡시계피산모 노-2-에틸헥산글리세릴, 파라메톡시 계피산 이소프로필, 디이소프로필 및 디이소프로필계피산에스테르 혼합물, 우로카닌산, 우로카닌산에틸, 히드록시메톡시벤조페논, 히드록시메톡시벤조페논술폰산 및 그 염, 디히드록시메톡시벤조페논, 디히드록시메톡시벤조페논디술폰산나트륨, 디히드록시벤조페논, 테트라히드록시벤조페논, 4-tert-부틸-4'-메톡시디벤조일메탄, 2,4,6-트리아닐리노-p-(카르보-2'-에틸헥실-1'-옥시)-1,3,5-트리아진, 2-(2-히드록시-5-메틸페닐)벤조트리아졸 등을 들 수 있다.UV absorbers include para-aminobenzoic acid, ethyl para-aminobenzoate, amyl para-aminobenzoate, octyl para-aminobenzoate, ethylene glycol salicylate, phenyl salicylate, octyl salicylate, benzyl salicylate, butylphenyl salicylate, homomenthyl salicylate, and benzyl cinnamate. , paramethoxycinnamic acid-2-ethoxyethyl, octyl paramethoxycinnamic acid, mono-2-ethylhexane glyceryl diparamethoxycinnamic acid, isopropyl paramethoxycinnamic acid, diisopropyl and diisopropylcinnamic acid ester mixture, Urocanic acid, ethyl urocanic acid, hydroxymethoxybenzophenone, hydroxymethoxybenzophenone sulfonic acid and its salts, dihydroxymethoxybenzophenone, dihydroxymethoxybenzophenone disulfonate sodium, dihydroxybenzoate Phenone, tetrahydroxybenzophenone, 4-tert-butyl-4'-methoxydibenzoylmethane, 2,4,6-trianilino-p-(carbo-2'-ethylhexyl-1'-oxy)- 1,3,5-triazine, 2-(2-hydroxy-5-methylphenyl)benzotriazole, etc. are mentioned.
살균제로서는 히노키티올, 트리클로산, 트리클로로히드록시디페닐에테르, 크로르헥시딘글루콘산염, 페녹시에탄올, 레조르신, 이소프로필메틸페놀, 아줄렌, 살리칠산, 진크필리티온, 염화벤잘코늄, 감광소 301 호, 모노니트로과이어콜나트륨, 운데시렌산 등을 들 수 있다.Disinfectants include hinokitiol, triclosan, trichlorohydroxydiphenyl ether, chlorhexidine gluconate, phenoxyethanol, resorcin, isopropylmethylphenol, azulene, salicylic acid, zincphyllithione, benzalkonium chloride, and photosensitive. Sub-No. 301, mononitroguaiacol sodium, undecirenic acid, etc. can be mentioned.
산화 방지제로서는 부틸히드록시아니솔, 갈릭산프로필, 엘리소르빈산 등을 들 수 있다.Antioxidants include butylhydroxyanisole, propyl gallate, and elisorbic acid.
pH 조정제로서는 시트르산, 시트르산나트륨, 말산, 말산나트륨, 프말산, 프말산나트륨, 숙신산, 숙신산나트륨, 수산화나트륨, 인산일수소나트륨 등을 들 수 있다.Examples of pH adjusters include citric acid, sodium citrate, malic acid, sodium malate, fumal acid, sodium fumalate, succinic acid, sodium succinate, sodium hydroxide, and sodium monohydrogen phosphate.
알코올로서는 세틸알코올 등의 고급 알코올을 들 수 있다.Examples of alcohol include higher alcohols such as cetyl alcohol.
또한, 이외에 첨가해도 되는 배합 성분은 이에 한정되는 것은 아니며, 또, 상기 어느 성분도 본 발명의 목적 및 효과를 손상시키지 않는 범위 내에서 배합 가능하다.Additionally, the ingredients that may be added are not limited to this, and any of the above ingredients can be blended within the range that does not impair the purpose and effect of the present invention.
본 발명의 화장료는 용액, 유화물, 점성형 혼합물 등의 형상을 취할 수 있다.The cosmetic of the present invention may take the form of a solution, emulsion, viscous mixture, etc.
본 발명의 화장료 조성물에 포함되는 성분은 유효성분으로서 화장료 조성물에 통상적으로 이용되는 성분들을 포함할 수 있으며, 예를 들면, 안정화제, 용해화제, 비타민, 안료 및 향료와 같은 통상적인 보조제 및 담체를 포함한다.The ingredients included in the cosmetic composition of the present invention may include ingredients commonly used in cosmetic compositions as active ingredients, for example, conventional auxiliaries and carriers such as stabilizers, solubilizers, vitamins, pigments, and fragrances. Includes.
본 발명의 피부 미백 및 피부 노화방지용 화장료 조성물은 당업계에서 통상적으로 제조되는 어떠한 제형으로도 제조될 수 있으며, 예를 들어 유액, 크림, 화장수, 팩, 파운데이션, 로션, 미용액, 모발화장료 등을 들 수 있다.The cosmetic composition for skin whitening and skin aging prevention of the present invention can be manufactured in any formulation commonly manufactured in the art, for example, emulsion, cream, lotion, pack, foundation, lotion, beauty essence, hair cosmetics, etc. You can.
구체적으로, 본 발명의 화장료 조성물은 스킨로션, 스킨소프너, 스킨토너, 밀크 로션, 아스트린젠트, 로션, 모이스쳐 로션, 영양로션, 맛사지크림, 영양크림, 모이스처크림, 핸드크림, 파운데이션, 에센스, 영양에센스, 팩, 비누, 클렌징폼, 클렌징로션, 클렌징크림, 헤어로션, 헤어토닉, 헤어에센스, 헤어샴푸, 헤어린스, 헤어트리트먼트, 바디로션 및 바디클린저의 제형을 포함한다.Specifically, the cosmetic composition of the present invention includes skin lotion, skin softener, skin toner, milk lotion, astringent, lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, foundation, essence, nutritional essence, It includes formulations of packs, soaps, cleansing foams, cleansing lotions, cleansing creams, hair lotions, hair tonics, hair essences, hair shampoos, hair rinses, hair treatments, body lotions, and body cleansers.
본 발명의 제형이 페이스트, 크림 또는 겔인 경우에는 담체 성분으로서 동물섬유, 식물섬유, 왁스, 파라핀, 전분, 트라칸트, 셀룰로오스 유도체, 폴리에틸렌글리콜, 실리콘, 벤토나이트, 실리카, 탈크 또는 산화 아연 등이 이용될 수 있다.When the formulation of the present invention is a paste, cream or gel, animal fiber, plant fiber, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier ingredient. You can.
본 발명의 제형이 파우더 또는 스프레이인 경우에는 담체 성분으로서 락토스, 탈크, 실리카, 알루미늄 히드록시드, 칼슘 실리케이트 또는 폴리아미드 파우더가 이용될 수 있고, 특히 스프레이인 경우에는 추가적으로 클로로플루오로히드로카본, 프로판/부탄 또는 디메틸 에테르와 같은 추진체를 포함할 수 있다.When the formulation of the present invention is a powder or spray, lactose, talc, silica, aluminum hydroxide, calcium silicate, or polyamide powder can be used as the carrier ingredient. In particular, when the formulation is a spray, chlorofluorohydrocarbon and propane may be used as carrier ingredients. /May contain propellants such as butane or dimethyl ether.
본 발명의 제형이 용액 또는 유탁액의 경우에는 담체 성분으로서 용매, 용매화제 또는 유탁화제가 이용되고, 예컨대 물, 에탄올, 이소프로판올, 에틸 카보네이트, 에틸 아세테이트, 벤질 알코올, 벤질 벤조에이트, 프로필렌글리콜, 1,3-부틸글리콜 오일, 글리세롤 지방족 에스테르, 폴리에틸렌 글리콜 또는 소르비탄의 지방산 에스테르가 있다.When the formulation of the present invention is a solution or emulsion, a solvent, solvating agent or emulsifying agent is used as a carrier component, such as water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1 , 3-butyl glycol oil, glycerol aliphatic esters, polyethylene glycol or fatty acid esters of sorbitan.
본 발명의 제형이 현탁액인 경우에는 담체 성분으로서 물, 에탄올 또는 프로필렌 글리콜과 같은 액상 희석제, 에톡실화 이소스테아릴 알코올, 폴리옥시에틸렌 소르비톨 에스테르 및 폴리옥시에틸렌 소르비탄 에스테르와 같은 현탁제, 미소결정성 셀룰로오스, 알루미늄 메타히드록시드, 벤토나이트, 아가 또는 트라칸트 등이 이용될 수 있다.When the formulation of the present invention is a suspension, the carrier ingredients include water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester, and polyoxyethylene sorbitan ester, and microcrystalline Cellulose, aluminum metahydroxide, bentonite, agar, or tracant may be used.
본 발명의 제형이 계면-활성제 함유 클린징인 경우에는 담체 성분으로서 지방족 알코올 설페이트, 지방족 알코올 에테르 설페이트, 설포숙신산 모노에스테르, 이세티오네이트, 이미다졸리늄 유도체, 메틸타우레이트, 사르코시네이트, 지방산 아미드 에테르 설페이트, 알킬아미도베타인, 지방족 알코올, 지방산 글리세리드, 지방산디에탄올아미드, 식물성 유, 리놀린 유도체 또는 에톡실화 글리세롤 지방산 에스테르 등이 이용될 수 있다.When the formulation of the present invention is a surfactant-containing cleansing agent, the carrier ingredients include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyl taurate, sarcosinate, and fatty acid amide. Ether sulfate, alkylamidobetaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, linoline derivative, or ethoxylated glycerol fatty acid ester can be used.
이하, 본 발명의 실시예를 첨부된 도면을 참고하여 보다 상세하게 설명하도록 한다. 그러나, 하기의 실시예는 본 발명의 내용을 구체화하기 위한 것일 뿐, 이에 의해 본 발명이 한정되는 것은 아닐 것이다.Hereinafter, embodiments of the present invention will be described in more detail with reference to the attached drawings. However, the following examples are only intended to embody the content of the present invention, and the present invention is not limited thereto.
<준비예 1> 복사나무꽃 추출물의 제조<Preparation Example 1> Preparation of peach tree flower extract
경상북도 청도군은 구릉이 많은 산지로 이루어져 있으며 넉넉한 일조량을 자랑하여 이 지역의 복숭아는 당도가 높고 과즙이 풍부하며 향이 뛰어난 것으로 알려져 있다. 봄철 청도군 지역에서 떨어진 복사나무꽃을 주워 사용하였다. 떨어진 복사나무의 꽃을 깨끗이 세척한 후 세절한 100g을 25℃에서 정제수 100ml로 1 내지 2시간 동안 3번 반복 추출하였다. 추출 후 5μm 필터로 여과하고 본 발명의 '복사나무꽃 추출물'로 사용하였다.Cheongdo-gun, Gyeongsangbuk-do, consists of a mountainous area with many hills and boasts ample sunlight, so peaches from this area are known to have high sugar content, abundant juice, and excellent aroma. We used peach tree flowers that fell in the Cheongdo-gun area in the spring. After thoroughly washing the fallen flowers of the peach tree, 100 g of the finely chopped flowers were extracted three times with 100 ml of purified water at 25°C for 1 to 2 hours. After extraction, it was filtered through a 5μm filter and used as the 'Papacea flower extract' of the present invention.
<준비예 2> 복숭아 추출물<Preparation Example 2> Peach extract
시판중인 청도 복숭아 100g을 세절하여 25℃에서 정제수 100ml로 1 내지 2시간 동안 3번 반복 추출하였다. 추출 후 5μm 필터로 여과하고 본 발명의 '복숭아 추출물'로 사용하였다.100 g of commercially available Cheongdo peaches were cut into pieces and extracted three times with 100 ml of purified water at 25°C for 1 to 2 hours. After extraction, it was filtered through a 5μm filter and used as the 'peach extract' of the present invention.
<준비예 3> 프랑스해안송껍질 추출물의 제조<Preparation Example 3> Preparation of French coastal pine bark extract
시판중인 프랑스해안송껍질(Pinus Pinaster) 100g을 세절하여 25℃에서 정제수 100ml로 1 내지 2시간 동안 3번 반복 추출하였다. 추출 후 5μm 필터로 여과하고 본 발명의 '프랑스해안송껍질 추출물'로 사용하였다.100 g of commercially available French coastal pine bark ( Pinus Pinaster ) was cut into small pieces and extracted three times with 100 ml of purified water at 25°C for 1 to 2 hours. After extraction, it was filtered through a 5μm filter and used as the 'French coastal pine bark extract' of the present invention.
<준비예 4> 감태 추출물의 제조<Preparation Example 4> Preparation of Ecklonia cava extract
시판중인 감태(Ecklonia cava) 100g을 세절하여 25℃에서 정제수 100ml로 1 내지 2시간 동안 3번 반복 추출하였다. 추출 후 5μm 필터로 여과하고 본 발명의 '감태 추출물'로 사용하였다.100 g of commercially available Ecklonia cava was cut into small pieces and extracted three times with 100 ml of purified water at 25°C for 1 to 2 hours. After extraction, it was filtered through a 5μm filter and used as the 'Ecklonia cava extract' of the present invention.
<준비예 5> 납작파래 추출물의 제조<Preparation Example 5> Preparation of flat seaweed extract
시판중인 납작파래(Enteromorpha Compressa) 100g을 세절하여 25℃에서 정제수 100ml로 1 내지 2시간 동안 3번 반복 추출하였다. 추출 후 5μm 필터로 여과하고 본 발명의 '납작파래 추출물'로 사용하였다.100 g of commercially available flat lettuce ( Enteromorpha Compressa ) was cut into small pieces and extracted three times with 100 ml of purified water at 25°C for 1 to 2 hours. After extraction, it was filtered through a 5μm filter and used as the 'flat seaweed extract' of the present invention.
<준비예 6> 라벤더 추출물의 제조<Preparation Example 6> Preparation of lavender extract
시판중인 라벤더(Lavandula angustifolia) 100g을 세절하여 25℃에서 정제수 100ml로 1 내지 2시간 동안 3번 반복 추출하였다. 추출 후 5μm 필터로 여과하고 본 발명의 '라벤더 추출물'로 사용하였다.100 g of commercially available lavender ( Lavandula angustifolia ) was cut into pieces and extracted three times with 100 ml of purified water at 25°C for 1 to 2 hours. After extraction, it was filtered through a 5μm filter and used as the 'lavender extract' of the present invention.
<준비예 7> 마시멜로잎/뿌리 추출물의 제조<Preparation Example 7> Preparation of marshmallow leaf/root extract
시판중인 마시멜로(Althaea officinalis) 잎 및 뿌리 100g을 세절하여 25℃에서 정제수 100ml로 1 내지 2시간 동안 3번 반복 추출하였다. 추출 후 5μm 필터로 여과하고 본 발명의 '마시멜로잎/뿌리 추출물'로 사용하였다.100 g of commercially available marshmallow ( Althaea officinalis ) leaves and roots were cut into small pieces and extracted three times with 100 ml of purified water at 25°C for 1 to 2 hours. After extraction, it was filtered through a 5μm filter and used as the 'marshmallow leaf/root extract' of the present invention.
<화장품의 제조예 1><Cosmetic manufacturing example 1>
상기 준비예 1 내지 3에 따른 혼합물 또는 상기 준비예 1 내지 5에 따른 혼합물은 목적에 따라 여러 형태의 화장품으로 제조 가능하다. 하기는 본 발명에 따른 복사나무꽃 추출물, 복숭아 추출물 및 프랑스해안송껍질 추출물 또는 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물을 활성성분으로 함유시킨 몇몇 화장품의 제조방법을 예시한 것으로 본 발명이 이에 한정되는 것은 아니다.The mixture according to Preparation Examples 1 to 3 or the mixture according to Preparation Examples 1 to 5 can be manufactured into various types of cosmetics depending on the purpose. The following describes the preparation of several cosmetics containing peach tree flower extract, peach extract, and French coastal pine bark extract or peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, and sea lettuce extract as active ingredients according to the present invention. The present invention is not limited to this as an example of the method.
1-1. 선크림의 제조예1-1. Manufacturing example of sunscreen
본 발명의 혼합물 1.00 중량부1.00 parts by weight of the mixture of the present invention
징크옥사이드 17.0 중량부Zinc oxide 17.0 parts by weight
사이클로헥사실록세인 8.00 중량부Cyclohexasiloxane 8.00 parts by weight
부틸옥틸살리실레이트 5.00 중량부Butyloctyl salicylate 5.00 parts by weight
프로판다이올 5.00 중량부Propanediol 5.00 parts by weight
프로필헵틸카프릴레이트 5.00 중량부Propylheptyl caprylate 5.00 parts by weight
아이소도데케인 3.00 중량부Isododecane 3.00 parts by weight
카프릴릴메티콘 3.00 중량부Caprylylmethicone 3.00 parts by weight
폴리글리세릴-3폴리다이메틸실록시에틸다이메티콘 3.00 중량부Polyglyceryl-3 polydimethylsiloxyethyldimethicone 3.00 parts by weight
소듐하이알루로네이트 0.02 중량부Sodium hyaluronate 0.02 parts by weight
다이스테아다이모늄헥토라이트 0.80 중량부Disteadimonium hectorite 0.80 parts by weight
마그네슘설페이트 0.80 중량부Magnesium sulfate 0.80 parts by weight
트라이에톡시카프릴릴실레인 0.60 중량부Triethoxycaprylylsilane 0.60 parts by weight
메틸메타크릴레이트크로스폴리머 0.50 중량부0.50 parts by weight of methyl methacrylate crosspolymer
폴리글리세릴-2다이폴리하이드록시스테아레이트 0.50 중량부Polyglyceryl-2dipolyhydroxystearate 0.50 parts by weight
라우릴폴리글리세릴-3폴리다이메틸실록시에틸다이메티콘 0.50 중량부Laurylpolyglyceryl-3 polydimethylsiloxyethyldimethicone 0.50 parts by weight
합성플루오르플로고파이트 0.48 중량부Synthetic fluorophlogopite 0.48 parts by weight
글리세릴카프릴레이트 0.10 중량부Glyceryl caprylate 0.10 parts by weight
다이카프릴릴카보네이트 0.03 중량부Dicaprylyl carbonate 0.03 parts by weight
마이카 0.02 중량부Mica 0.02 parts by weight
1,2-헥산다이올 0.50 중량부0.50 parts by weight of 1,2-hexanediol
카프릴릴글라이콜 0.10 중량부Caprylyl glycol 0.10 parts by weight
에틸헥실글리세린 0.05 중량부0.05 parts by weight of ethylhexylglycerin
황색산화철 0.02 중량부Yellow iron oxide 0.02 parts by weight
향료 0.20 중량부Fragrance 0.20 parts by weight
적색산화철 미량Trace amounts of red iron oxide
흑색산화철 미량Trace amounts of black iron oxide
토코페롤 미량Trace amounts of tocopherol
부틸렌글라이콜 미량Trace amount of butylene glycol
정제수 잔량Purified water remaining
1-2. 유연 화장수의 제조예1-2. Manufacturing example of flexible lotion
본 발명의 혼합물 10.0 중량부10.0 parts by weight of the mixture of the present invention
1,3-부틸렌글리콜 1.00 중량부1,3-butylene glycol 1.00 parts by weight
디소듐이디티에이 0.05 중량부Disodium EDTA 0.05 parts by weight
알란토인 0.10 중량부Allantoin 0.10 parts by weight
디포타슘글리시리제이트 0.05 중량부Dipotassium glycyrrhizate 0.05 parts by weight
시트르산 0.01 중량부Citric acid 0.01 parts by weight
소듐시트레이트 0.02 중량부Sodium citrate 0.02 parts by weight
글리세레스-26 1.00 중량부Glycereth-26 1.00 parts by weight
알부틴 2.00 중량부Arbutin 2.00 parts by weight
하이드로제네이티드캐스터오일 1.00 중량부Hydrogenated castor oil 1.00 parts by weight
에탄올 30.0 중량부30.0 parts by weight of ethanol
보존제 미량Trace amount of preservative
착색제 미량Trace amount of colorant
착향제 미량Trace amount of flavoring agent
정제수 잔량Purified water remaining
1-3. 영양 크림의 제조예1-3. Manufacturing example of nutritious cream
본 발명의 혼합물 10.0 중량부10.0 parts by weight of the mixture of the present invention
1,3-부틸렌글리콜 7.00 중량부7.00 parts by weight of 1,3-butylene glycol
글리세린 1.00 중량부Glycerin 1.00 parts by weight
D-판테놀 0.10 중량부D-Panthenol 0.10 parts by weight
식물 추출물 3.20 중량부3.20 parts by weight of plant extract
마그네슘알루미늄실리케이트 0.30 중량부Magnesium aluminum silicate 0.30 parts by weight
PEG-40 스테아레이트 1.20 중량부PEG-40 stearate 1.20 parts by weight
스테아르산 2.00 중량부Stearic acid 2.00 parts by weight
폴리소르베이트 60 1.50 중량부Polysorbate 60 1.50 parts by weight
친유형글리세릴스테아레이트 2.00 중량부Lipophilic glyceryl stearate 2.00 parts by weight
소르비탄세스퀴올리에이트 1.50 중량부Sorbitan sesquioleate 1.50 parts by weight
세테아릴알코올 3.00 중량부Cetearyl alcohol 3.00 parts by weight
미네랄오일 4.00 중량부Mineral oil 4.00 parts by weight
스쿠알란 3.80 중량부Squalane 3.80 parts by weight
카르릴릭/카프릭트리글리세라이드 2.80 중량부Carlylic/capric triglyceride 2.80 parts by weight
식물성오일 1.80 중량부Vegetable oil 1.80 parts by weight
디메치콘 0.40 중량부Dimethicone 0.40 parts by weight
디포슘글리시리제이트 미량Dipotium glycyrrhizate trace amount
알란토인 미량Trace amounts of allantoin
소듐 히아루로네이트 미량Sodium Hyaluronate Trace
토코페릴아세테이트 적량Tocopheryl acetate appropriate amount
트리에탄올아민 적량Triethanolamine dosage
보존제 적량Preservative amount
착향제 적량Flavoring agent appropriate amount
정제수 잔량Purified water remaining
1-4. 로션의 제조예1-4. Lotion manufacturing example
본 발명의 혼합물 3.00 중량부3.00 parts by weight of the mixture of the present invention
프로필렌글리콜 6.00 중량부Propylene glycol 6.00 parts by weight
글리세린 4.00 중량부Glycerin 4.00 parts by weight
트리에탄올아민 3.00 중량부Triethanolamine 3.00 parts by weight
토코페릴아세테이트 5.00 중량부Tocopheryl acetate 5.00 parts by weight
유동 파라핀 3.00 중량부3.00 parts by weight of liquid paraffin
스쿠알란 2.00 중량부Squalane 2.00 parts by weight
마카다미너트오일 2.00 중량부Macadamia nut oil 2.00 parts by weight
폴리소르베이트 60 1.50 중량부Polysorbate 60 1.50 parts by weight
소르비탄세스퀴올레이트 1.00 중량부Sorbitan sesquioleate 1.00 parts by weight
카르복시비닐폴리머 1.00 중량부Carboxy vinyl polymer 1.00 parts by weight
방부제, 향, 색소 미량Trace amounts of preservatives, fragrance, and coloring
증류수 잔량Distilled water remaining
1-5. 에센스의 제조예1-5. Preparation example of essence
본 발명의 혼합물 1.50 중량부1.50 parts by weight of the mixture of the present invention
글리세린 10.0 중량부Glycerin 10.0 parts by weight
베타인 5.00 중량부Betaine 5.00 parts by weight
PEG 1500 2.00 중량부PEG 1500 2.00 parts by weight
알란토인 0.10 중량부Allantoin 0.10 parts by weight
DL-판테놀 0.30 중량부DL-Panthenol 0.30 parts by weight
EDTA-2Na 0.02 중량부EDTA-2Na 0.02 parts by weight
벤조페논-9 0.04 중량부Benzophenone-9 0.04 parts by weight
하이드록시에칠셀룰로오스 0.10 중량부0.10 parts by weight of hydroxyethyl cellulose
소듐하이알루로네이트 8.00 중량부Sodium hyaluronate 8.00 parts by weight
카르복시비닐폴리머 0.20 중량부0.20 parts by weight of carboxyvinyl polymer
트리에탄올아민 0.18 중량부Triethanolamine 0.18 parts by weight
옥틸도데칸올 0.30 중량부Octyldodecanol 0.30 parts by weight
옥틸도데세스-16 0.40 중량부Octyldodeceth-16 0.40 parts by weight
에탄올 6.00 중량부Ethanol 6.00 parts by weight
방부제, 향, 색소 미량Trace amounts of preservatives, fragrance, and coloring
정제수 잔량Purified water remaining
1-6. 마스크 팩용 유액의 제조예1-6. Manufacturing example of emulsion for mask pack
본 발명의 혼합물 1.00 중량부1.00 parts by weight of the mixture of the present invention
폴리비닐알코올 15.0 중량부15.0 parts by weight of polyvinyl alcohol
셀룰로오스 검 0.15 중량부Cellulose gum 0.15 parts by weight
글리세린 3.00 중량부Glycerin 3.00 parts by weight
PEG 1500 2.00 중량부PEG 1500 2.00 parts by weight
사이클로덱스트린 0.15 중량부0.15 parts by weight of cyclodextrin
DL-판테놀 0.40 중량부DL-Panthenol 0.40 parts by weight
알란토인 0.10 중량부Allantoin 0.10 parts by weight
글리시리진산모노암모늄 0.30 중량부Monoammonium glycyrrhizinate 0.30 parts by weight
니코틴아마이드 0.50 중량부Nicotinamide 0.50 parts by weight
에탄올 6.00 중량부Ethanol 6.00 parts by weight
PEG 40 경화 피마자유 0.30 중량부0.30 parts by weight of PEG 40 hydrogenated castor oil
방부제, 향, 색소 미량Trace amounts of preservatives, fragrance, and coloring
정제수 잔량Purified water remaining
<실험예 1> 항산화 효과 확인<Experimental Example 1> Confirmation of antioxidant effect
1-1. DPPH 라디칼 소거능1-1. DPPH radical scavenging ability
상기 준비예 1 내지 7에서 제조한 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물, 납작파래 추출물, 라벤더 추출물 및 마시멜로잎/뿌리 추출물의 항산화 효과를 평가하기 위해, DPPH assay를 실시하였다. 이때, 양성대조군은 아스코르브산(ascorbic acid, AA)를 사용하였다. DPPH를 0.2 mM 농도로 에틸알코올에 용해하고, DPPH solution 100㎕와 각 시료 100㎕를 20분간 반응시킨 후 흡광도를 분광광도계(microplate reader)로 517nm에서 흡광도(OD)를 측정하였다. 또한, DPPH 라디칼 소거능은 하기 수학식 1로 계산하였고, 결과를 하기 표 1에 나타내었다.To evaluate the antioxidant effect of the peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, flat seaweed extract, lavender extract, and marshmallow leaf/root extract prepared in Preparation Examples 1 to 7, DPPH assay was performed. did. At this time, ascorbic acid (AA) was used as the positive control group. DPPH was dissolved in ethyl alcohol at a concentration of 0.2 mM, 100 μl of the DPPH solution and 100 μl of each sample were reacted for 20 minutes, and then the absorbance (OD) was measured at 517 nm using a spectrophotometer (microplate reader). Additionally, the DPPH radical scavenging ability was calculated using Equation 1 below, and the results are shown in Table 1 below.
[수학식 1][Equation 1]
DPPH inhibition(%) = [1-(Abssample/Abscontrol)] × 100DPPH inhibition(%) = [1-(Abssample/Abscontrol)] × 100
상기 표 1에서 확인할 수 있는 것처럼 각각의 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물, 납작파래 추출물, 라벤더 추출물 및 마시멜로잎/뿌리 추출물은 양성대조군인 아스코르브산 보다는 낮은 DPPH 라디칼 소거능을 확인하였다. 다만, 7가지의 시료 중 복사나무꽃 추출물에서 가장 높은 DPPH 라디칼 소거능을 보였으며, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물, 납작파래 추출물, 라벤더 추출물 및 마시멜로잎/뿌리 추출물 순으로 DPPH 라디칼 소거능을 나타내었다.As can be seen in Table 1, each of the peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, flat seaweed extract, lavender extract, and marshmallow leaf/root extract has a lower DPPH radical scavenging ability than ascorbic acid, which is a positive control. was confirmed. However, among the seven samples, peach tree flower extract showed the highest DPPH radical scavenging activity, followed by peach extract, French coastal pine bark extract, Ecklonia cava extract, sea lettuce extract, lavender extract, and marshmallow leaf/root extract in that order. indicated.
1-2. ABTS 라디칼 소거능1-2. ABTS radical scavenging ability
상기 준비예 1 내지 7에서 제조한 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물, 납작파래 추출물, 라벤더 추출물 및 마시멜로잎/뿌리 추출물의 항산화 효과를 평가하기 위해, ABTS assay를 실시하였다. 이때, 양성대조군은 아스코르브산(ascorbic acid, AA)를 사용하였다. 7mM ABTS(2,2'-azino-bis(3-ethylbenzothiazoline-6- sulfonic acid))와 2.45mM 과황산칼륨(potassium persulfate)를 1:1로 혼합하여 16시간동안 암소에 보관하여 ABTS solution을 제조하였다. 제조된 ABTS solution을 50%(v/v) 메탄올에 희석하여 745nm에서 흡광도 0.7 ± 0.02가 되도록 조절하였다. ABTS solution 180㎕와 각 시료 20㎕를 10분간 반응시킨 후 microplate reader로 745nm에서 흡광도를 측정하였다. ABTS 라디칼 소거능은 하기 수학식 2로 계산하였고, 결과를 하기 표 2에 나타내었다.To evaluate the antioxidant effect of the peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, flat seaweed extract, lavender extract, and marshmallow leaf/root extract prepared in Preparation Examples 1 to 7, ABTS assay was performed. did. At this time, ascorbic acid (AA) was used as the positive control group. Prepare ABTS solution by mixing 7mM ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) and 2.45mM potassium persulfate in a 1:1 ratio and storing in the dark for 16 hours. did. The prepared ABTS solution was diluted in 50% (v/v) methanol and adjusted to an absorbance of 0.7 ± 0.02 at 745 nm. After reacting 180 μl of ABTS solution and 20 μl of each sample for 10 minutes, the absorbance was measured at 745 nm with a microplate reader. ABTS radical scavenging ability was calculated using Equation 2 below, and the results are shown in Table 2 below.
[수학식 2][Equation 2]
ABTS inhibition(%) = [1-(Abssample/Abscontrol)] × 100ABTS inhibition(%) = [1-(Abssample/Abscontrol)] × 100
상기 표 2에서 확인할 수 있는 것처럼 각각의 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물, 납작파래 추출물, 라벤더 추출물 및 마시멜로잎/뿌리 추출물은 양성대조군인 아스코르브산 보다는 낮은 ABTS 라디칼 소거능을 확인하였다. 다만, 7가지의 시료 중 복사나무꽃 추출물에서 가장 높은 ABTS 라디칼 소거능을 보였으며, 복숭아 추출물, 프랑스해안송껍질 추출물, 납작파래 추출물, 감태 추출물, 마시멜로잎/뿌리 추출물 및 라벤더 추출물 순으로 ABTS 라디칼 소거능을 나타내었다. 이어서 항산화 효과를 나타내는 시료들을 서로 혼합하여 항산화 상승효과를 확인하기 위해 다음과 같이 실험을 진행하였다.As can be seen in Table 2 above, each of the peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, flat seaweed extract, lavender extract, and marshmallow leaf/root extract has a lower ABTS radical scavenging ability than ascorbic acid, which is a positive control. was confirmed. However, among the seven samples, peach tree flower extract showed the highest ABTS radical scavenging activity, followed by peach extract, French coastal pine bark extract, flat lettuce extract, Ecklonia cava extract, marshmallow leaf/root extract, and lavender extract in that order. indicated. Next, samples showing antioxidant effects were mixed together and the following experiment was conducted to confirm the antioxidant synergistic effect.
<실험예 2> 항산화 상승효과 확인<Experimental Example 2> Confirmation of antioxidant synergistic effect
2-1. DPPH 라디칼 소거능2-1. DPPH radical scavenging ability
상기 실험예 1에서 항산화 효과가 비교적 높은 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물 각 시료를 혼합하여 DPPH 라디칼 소거능을 통한 항산화 상승효과를 확인하였다. 실험방법은 상기 실험예 1-1과 동일하게 진행하였으며, 5개의 시료를 각각 여러 중량비로 혼합하여 항산화 상승효과를 확인하였다(표 3).In Experimental Example 1, samples of peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, and sea lettuce extract, which have relatively high antioxidant effects, were mixed to confirm the synergistic antioxidant effect through DPPH radical scavenging ability. The experimental method was conducted in the same manner as in Experimental Example 1-1, and the antioxidant synergistic effect was confirmed by mixing five samples at various weight ratios (Table 3).
(복사나무꽃:복숭아:프랑스해안송껍질) 또는(peach tree flower: peach: French coastal pine bark) or
(복사나무꽃:복숭아:프랑스해안송껍질:감태:납작파래)(Panax tree flowers: Peach: French coastal pine bark: Gamtae: Flat green seaweed)
(1:1:1)(1:1:1)
(2:1:1)(2:1:1)
(3:1:1)(3:1:1)
(4:1:1)(4:1:1)
(3:2:1)(3:2:1)
(1:1:1:1:1)(1:1:1:1:1)
(3:2:1:1:1)(3:2:1:1:1)
(6:4:2:1:1)(6:4:2:1:1)
상기 표 3에서와 같이 각각의 추출물의 항산화 효과에서 비교적 효과가 좋은 것으로 확인되었던 복사나무꽃 추출물, 복숭아 추출물 및 프랑스해안송껍질 추출물을 혼합한 실시예 1 내지 5의 경우 동량으로 혼합한 경우에서 보다 복사나무꽃 추출물의 중량비를 높이는 경우에서 높은 항산화 효과를 확인할 수 있었고, 최종적으로는 3:2:1의 비율로 혼합하는 경우(실시예 5)에서 가장 높은 항산화 효과를 확인할 수 있었다.As shown in Table 3 above, in the case of Examples 1 to 5 in which peach tree flower extract, peach extract, and French coastal pine bark extract were mixed, which were confirmed to be relatively effective in terms of the antioxidant effect of each extract, the results were higher than when mixed in equal amounts. A high antioxidant effect was confirmed when the weight ratio of prickly pear flower extract was increased, and ultimately, the highest antioxidant effect was confirmed when mixed at a ratio of 3:2:1 (Example 5).
이어서 감태 추출물 및 납작파래 추출물을 더 포함하여 혼합하는 경우에는 최종 혼합비인 6:4:2:1:1(=3:2:1:0.5:0.5)의 중량비로 혼합하는 경우(실시예 8)에 미량이나마 항산화 효능이 증가되는 것을 확인할 수 있었다.Subsequently, when mixing the Ecklonia cava extract and the Lettuce extract, the weight ratio is 6:4:2:1:1 (=3:2:1:0.5:0.5), which is the final mixing ratio (Example 8) It was confirmed that the antioxidant efficacy was increased, albeit in a small amount.
2-2. ABTS 라디칼 소거능2-2. ABTS radical scavenging ability
상기 실험예 1에서 항산화 효과가 비교적 높은 복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물 시료를 혼합하여 ABTS 라디칼 소거능을 통한 항산화 상승효과를 확인하였다. 실험방법은 상기 실험예 2-1과 동일하게 진행하였으며, 5개의 시료를 각각 여러 중량비로 혼합하여 항산화 상승효과를 확인하였다(표 4).In Experimental Example 1, peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, and sea lettuce extract samples, which have relatively high antioxidant effects, were mixed to confirm the antioxidant synergistic effect through ABTS radical scavenging ability. The experimental method was conducted in the same manner as in Experimental Example 2-1, and the antioxidant synergistic effect was confirmed by mixing five samples at various weight ratios (Table 4).
(복사나무꽃:복숭아:프랑스해안송껍질:감태:납작파래)(Panax tree flowers: Peach: French coastal pine bark: Gamtae: Flat green seaweed)
(1:1:1)(1:1:1)
(2:1:1)(2:1:1)
(3:1:1)(3:1:1)
(4:1:1)(4:1:1)
(3:2:1)(3:2:1)
(1:1:1:1:1)(1:1:1:1:1)
(3:2:1:1:1)(3:2:1:1:1)
(6:4:2:1:1)(6:4:2:1:1)
상기 표 4에서와 같이 각각의 추출물의 항산화 효과에서 비교적 효과가 좋은 것으로 확인되었던 복사나무꽃 추출물, 복숭아 추출물 및 프랑스해안송껍질 추출물을 혼합한 실시예 1 내지 5의 경우 동량으로 혼합한 경우에서 보다 복사나무꽃 추출물의 중량비를 높이는 경우에서 높은 항산화 효과를 확인할 수 있었고, 최종적으로는 3:2:1의 비율로 혼합하는 경우(실시예 5)에서 가장 높은 항산화 효과를 확인할 수 있었다.As shown in Table 4 above, in the case of Examples 1 to 5, in which peach tree flower extract, peach extract, and French coastal pine bark extract were mixed, which were confirmed to be relatively effective in terms of the antioxidant effect of each extract, the results were higher than when mixed in equal amounts. A high antioxidant effect was confirmed when the weight ratio of prickly pear flower extract was increased, and ultimately, the highest antioxidant effect was confirmed when mixed at a ratio of 3:2:1 (Example 5).
이어서 상기 추출물에 감태 추출물 및 납작파래 추출물을 더 포함하여 혼합하는 경우에는 최종 혼합비인 6:4:2:1:1(=3:2:1:0.5:0.5)의 중량비로 혼합하는 경우(실시예 8)에 미량이나마 항산화 효능이 증가되는 것을 확인할 수 있었다.Subsequently, when the extract is further mixed with the Ecklonia cava extract and the Lettuce extract, it is mixed at a weight ratio of 6:4:2:1:1 (=3:2:1:0.5:0.5), which is the final mixing ratio (performed In Example 8), it was confirmed that the antioxidant efficacy was increased, albeit in a small amount.
<실험예 3> 미백 활성 테스트<Experimental Example 3> Whitening activity test
미백활성 테스트에 많이 사용되는 티로시나제(Tyrosinase) 억제 효과 테스트는 도파크롬(DOPAchrome)법을 이용하여 측정하였다. 머쉬룸 티로시나아제(mushroom tyrosinase) 150㎕와 2.5mM L-tyrosine 225㎕, 0.4M HEPES 버퍼 225㎕, 에탄올 용액 또는 1 mg/mL 농도의 시료(실시예 5 또는 실시예 8의 혼합물) 300 ㎕를 혼합한 후 각각의 흡광도를 475 nm의 파장에서 측정하였다. 본 발명의 실시예 5 또는 실시예 8에 따른 티로시나제 억제효과를 객관적으로 알아보기 위해 양성대조군으로는 대표적인 미백제로 알려진 코직산(kojic acid)를 사용하였으며, 상기 측정된 각 시료용액의 흡광도를 산출하여 티로시나제 활성 저해 수치를 하기 수학식 3을 이용하여 계산하여 표 5에 나타내었다.The tyrosinase inhibition effect test, which is widely used in whitening activity tests, was measured using the DOPAchrome method. 150 μl of mushroom tyrosinase, 225 μl of 2.5mM L-tyrosine, 225 μl of 0.4M HEPES buffer, and 300 μl of ethanol solution or 1 mg/mL sample (mixture of Example 5 or Example 8) After mixing, each absorbance was measured at a wavelength of 475 nm. In order to objectively examine the tyrosinase inhibitory effect according to Example 5 or Example 8 of the present invention, kojic acid, known as a representative whitening agent, was used as a positive control, and the absorbance of each sample solution measured above was calculated to determine the tyrosinase The activity inhibition values were calculated using Equation 3 below and are shown in Table 5.
[수학식 3][Equation 3]
Tyrosinase Inhibition(%) = [1-(Abssample/Abscontrol)] × 100Tyrosinase Inhibition(%) = [1-(Abssample/Abscontrol)] × 100
상기 표 5의 결과와 같이 본 발명의 우수한 항산화 효능을 나타내는 실시예 5 및 실시예 8은 양성대조군인 코직산와 거의 유사한 티로시나제 활성 억제 효능을 보이는 것으로 확인되었다.As shown in the results in Table 5 above, Examples 5 and 8, which show excellent antioxidant efficacy of the present invention, were confirmed to have a tyrosinase activity inhibitory effect almost similar to that of kojic acid, a positive control group.
<실험예 4> 자외선차단 효과 테스트<Experimental Example 4> UV blocking effect test
상기 실험예 1 내지 2에서 항산화 효과가 좋은 실시예 5 및 실시예 8의 혼합물을 이용하여 상기 <화장품의 제조예 1>의 '1-1. 선크림의 제조예'에 따라 선크림을 제조(도 1)하였고, 이를 이용하여 자외선차단 효과 테스트를 진행하였다. 자외선 차단 효과를 파악하기 위하여 자외선 차단지수 분석기(SPF analyser 290S, Laser componets, UK)를 이 용하여 실시예 5 또는 실시예 8로 제조된 선크림과 시중에 판매중인 선크림 1 및 2를 대상으로 자외선 차단 지수를 10회 실시하여 평균값을 측정하였다. 그 결과는 하기 표 6과 같다.In Experimental Examples 1 to 2, the mixture of Examples 5 and 8, which have good antioxidant effects, was used to produce '1-1' of <Preparation Example 1 of Cosmetics>. Sunscreen was manufactured (Figure 1) according to the 'Sunscreen manufacturing example', and a UV blocking effect test was conducted using it. In order to determine the UV protection effect, a UV protection factor analyzer (SPF analyzer 290S, Laser components, UK) was used to measure the UV protection factors of the sunscreen manufactured in Example 5 or Example 8 and commercially available sunscreens 1 and 2. This was performed 10 times and the average value was measured. The results are shown in Table 6 below.
상기 표 5에서 나타낸 것과 같이 본 발명의 실시예 5 또는 실시예 8로 제조된 선크림은 시중에 판매중인 선크림 대비 우수한 자외선차단 효과를 가지는 것으로 확인되었다.As shown in Table 5, the sunscreen prepared in Example 5 or Example 8 of the present invention was confirmed to have a superior UV blocking effect compared to sunscreens sold on the market.
<실험예 5> 피부자극 테스트<Experimental Example 5> Skin irritation test
상기 실험예 1 내지 2에서 항산화 효과가 좋은 실시예 5 및 실시예 8의 혼합물을 이용하여 상기 <화장품의 제조예 1>의 '1-1. 선크림의 제조예'에 따라 선크림을 제조(도 1)하였고, 제조된 선크림을 이용하여 48시간 동안 피부(척추 중심으로 어깨뼈와 허리선 사이)에 첩포하였으며, 첩포를 제거한 후 30분 경과 후, 24시간 경과후, 120시간 경과 후에 시험부위를 관찰하였다. 피부반응은 국제 접촉피부염연구회(ICDRG)의 평가기준에 따라 자극정도를 다음과 같이 분류하여 표시하였으며, 그 결과 하기 표 7에 나타내었다.In Experimental Examples 1 to 2, the mixture of Examples 5 and 8, which have good antioxidant effects, was used to produce '1-1' of <Preparation Example 1 of Cosmetics>. Sunscreen was prepared according to the 'Sunscreen manufacturing example' (Figure 1), and the prepared sunscreen was applied to the skin (centered on the spine, between the shoulder blades and the waist line) for 48 hours. After 30 minutes, the patch was removed. The test area was observed after 24 hours and after 120 hours. Skin reactions were classified and expressed by the degree of irritation as follows according to the evaluation standards of the International Contact Dermatitis Research Group (ICDRG), and the results are shown in Table 7 below.
-: 무자극, ±: 미자극(희미한 또는 가까스로 감지할 수 있는 가벼운 홍반), +: 경자극(경계가 뚜렷하나 약한 홍반, 부종 및 구진), ++: 중자극(뚜렷한 홍반, 구진 및 소수포), +++: 강자극(심한 홍반 및 대수포, 가피형성)-: No irritant, ±: Minor irritant (difficult or barely detectable erythema), +: Mild irritant (well-defined but mild erythema, edema and papules), ++: Moderate irritant (marked erythema, papules and vesicles) ), +++: Strong irritation (severe erythema, blisters, crust formation)
상기 표 7에서 확인할 수 있는 것처럼 본 발명의 실시예 5 또는 실시예 8의 혼합물을 이용하여 제조된 선크림은 피부자극테스트 결과 무자극으로 판정되었다.As can be seen in Table 7, the sunscreen prepared using the mixture of Example 5 or Example 8 of the present invention was determined to be non-irritating as a result of the skin irritation test.
<실험예 6> 선크림 입자 크기 측정<Experimental Example 6> Sunscreen particle size measurement
상기 실험예 1 내지 2에서 항산화 효과가 좋은 실시예 5 및 실시예 8의 혼합물을 이용하여 상기 <화장품의 제조예 1>의 '1-1. 선크림의 제조예'에 따라 선크림을 제조하여 입자 크기를 측정하였다. 시료 250mg과 용매 50ml를 섞은 후 1ml를 취해 사이즈 측정용 용기로 옮겼다. Dynamic light scattering method로 입자경을 측정하여, cumulant analysis 결과로 얻어진 평균입자경, 다분산도를 기록하였다. 그 결과는 도 2에 나타내었고, 선크림을 물로 희석한 후 PdI(polydispersity index; 다분산지수)를 측정한 결과 선크림의 분산도는 0.208 ± 0.089였고, 평균입자의 크기는 3726 ± 296.1nm이었으며, 100nm 이하의 입자는 0.00% 존재하였다.In Experimental Examples 1 to 2, the mixture of Examples 5 and 8, which have good antioxidant effects, was used to produce '1-1' of <Preparation Example 1 of Cosmetics>. Sunscreen was prepared according to 'Sunscreen manufacturing example' and particle size was measured. After mixing 250 mg of sample and 50 ml of solvent, 1 ml was taken and transferred to a container for size measurement. The particle size was measured using the dynamic light scattering method, and the average particle size and polydispersity obtained as a result of cumulant analysis were recorded. The results are shown in Figure 2. As a result of measuring the PdI (polydispersity index) after diluting the sunscreen with water, the dispersion degree of the sunscreen was 0.208 ± 0.089, and the average particle size was 3726 ± 296.1nm, 100nm. The following particles were present at 0.00%.
이상에서 살펴본 바와 같이, 본 발명의 구체적인 실시예를 상세하게 설명되었으나, 본 발명의 사상을 이해하는 당업자는 동일한 사상의 범위 내에서 다른 구성요소를 추가, 변경, 삭제 등을 통하여, 퇴보적인 다른 발명이나 본 발명 사상의 범위 내에 포함되는 다른 실시예를 용이하게 제안할 수 있을 것이다. 그러므로 이상에서 기술한 실시예들은 모든 면에서 예시적인 것이며 한정적이 아닌 것으로 이해해야만 한다. 본 발명의 범위는 상술한 상세한 설명보다는 후술하는 특허청구의 범위에 의하여 나타내어지며, 특허청구의 범위의 의미 및 범위 그리고 그 균등 개념으로부터 도출되는 모든 변경 또는 변형된 형태가 본 발명의 범위에 포함되는 것으로 해석되어야 한다.As discussed above, specific embodiments of the present invention have been described in detail, but those skilled in the art who understand the spirit of the present invention may add, change, delete, etc. other components within the scope of the same spirit, thereby creating other regressive inventions. However, other embodiments that are included within the scope of the present invention can be easily proposed. Therefore, the embodiments described above should be understood in all respects as illustrative and not restrictive. The scope of the present invention is indicated by the scope of the claims described below rather than the detailed description above, and all changes or modified forms derived from the meaning and scope of the claims and their equivalent concepts are included in the scope of the present invention. It should be interpreted as
Claims (5)
An antioxidant cosmetic composition containing as an active ingredient a mixture of peach tree flower extract, peach extract, and French coastal pine bark extract.
상기 혼합물은,
복사나무꽃 추출물, 복숭아 추출물 및 프랑스해안송껍질 추출물이 0.5~4 : 0.5~3 : 0.5~2의 중량비로 혼합되는 것을 특징으로 하는, 항산화용 화장료 조성물.
According to paragraph 1,
The mixture is,
An antioxidant cosmetic composition, characterized in that prickly pear flower extract, peach extract, and French coastal pine bark extract are mixed in a weight ratio of 0.5-4:0.5-3:0.5-2.
상기 조성물은,
감태 추출물 및 납작파래 추출물을 더 포함하는 것이며,
복사나무꽃 추출물, 복숭아 추출물, 프랑스해안송껍질 추출물, 감태 추출물 및 납작파래 추출물이 0.5~7 : 0.5~3 : 0.5~2 : 0.5~2 : 0.5~2의 중량비로 혼합되는 것을 특징으로 하는, 항산화용 화장료 조성물.
According to paragraph 1,
The composition is,
It further contains gamtae extract and flat seaweed extract,
Characterized in that peach tree flower extract, peach extract, French coastal pine bark extract, Ecklonia cava extract, and flat seaweed extract are mixed in a weight ratio of 0.5~7:0.5~3:0.5~2:0.5~2:0.5~2, Antioxidant cosmetic composition.
상기 조성물은,
선크림, 스킨로션, 스킨소프너, 스킨토너, 아스트린젠트, 로션, 밀크로션, 모이스쳐 로션, 영양로션, 맛사지크림, 영양크림, 모이스처크림, 핸드크림, 파운데이션, 에센스, 영양에센스, 클렌징, 팩, 비누, 바디로션 및 바디클린저로 구성된 제형에서 선택된 하나 이상의 제형인 것을 특징으로 하는, 항산화용 화장료 조성물.
According to paragraph 1,
The composition is,
Sunscreen, skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nutritional lotion, massage cream, nutritional cream, moisture cream, hand cream, foundation, essence, nutritional essence, cleansing, pack, soap, body An antioxidant cosmetic composition, characterized in that it is one or more formulations selected from formulations consisting of lotions and body cleansers.
상기 조성물은,
징크옥사이드(Zinc Oxide), 사이클로헥사실록세인(Cyclohexasiloxane), 부틸옥틸살리실레이트(Butyloctyl Salicylate), 프로판다이올(Propanediol), 프로필헵틸카프릴레이트(Propylheptyl Caprylate), 아이소도데케인(Isododecane), 카프릴릴메티콘(Caprylyl Methicone), 폴리글리세릴-3폴리다이메틸실록시에틸다이메티콘(Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone), 소듐하이알루로네이트(Sodium Hyaluronate), 다이스테아다이모늄헥토라이트(Disteardimonium Hectorite), 마그네슘설페이트(Magnesium Sulfate), 트라이에톡시카프릴릴실레인(Triethoxycaprylylsilane), 메틸메타크릴레이트크로스폴리머(Methyl Methacrylate Crosspolymer), 폴리글리세릴-2다이폴리하이드록시스테아레이트(Polyglyceryl-2 Dipolyhydroxystearate), 라우릴폴리글리세릴-3폴리다이메틸실록시에틸다이메티콘(Lauryl Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone), 합성플루오르플로고파이트(Synthetic Fluorphlogopite), 글리세릴카프릴레이트(Glyceryl Caprylate), 다이카프릴릴카보네이트(Dicaprylyl Carbonate), 마이카(Mica), 토코페롤(Tocopherol), 1,2-헥산다이올(1,2-Hexanediol), 항료(Fragrance), 카프릴릴글라이콜(Caprylyl Glycol), 에틸헥실글리세린(Ethylhexylglycerin), 황색산화철(Iron Oxide Yellow, Hydrated Ferric Oxide), 적색산화철(Iron Oxide Red, Ferric Oxide), 흑색산화철(Iron Oxide Black, Ferrous-Ferric Oxide), 부틸렌글라이콜(Butylene Glycol) 및 정제수를 더 포함하는 것을 특징으로 하는, 항산화용 화장료 조성물.According to paragraph 1,
The composition is,
Zinc Oxide, Cyclohexasiloxane, Butyloctyl Salicylate, Propanediol, Propylheptyl Caprylate, Isododecane, Caprylyl Methicone, Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Sodium Hyaluronate, Disteardimonium Hectorite ), Magnesium Sulfate, Triethoxycaprylylsilane, Methyl Methacrylate Crosspolymer, Polyglyceryl-2 Dipolyhydroxystearate , Lauryl Polyglyceryl-3 Polydimethylsiloxyethyl Dimethicone, Synthetic Fluorphlogopite, Glyceryl Caprylate, Dicaprylyl Carbonate (Dicaprylyl Carbonate), Mica, Tocopherol, 1,2-Hexanediol, Fragrance, Caprylyl Glycol, Ethylhexylglycerin ), Iron Oxide Yellow, Hydrated Ferric Oxide, Iron Oxide Red, Ferric Oxide, Iron Oxide Black, Ferrous-Ferric Oxide, Butylene Glycol and purified water. A cosmetic composition for antioxidant, characterized in that it contains.
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https://horhor.tistory.com/201, 쁘리더머의 백과사전, 활성산소로부터 피부를 보호하는 ‘복사나무 추출물’의 효능 및 특징, 2020.06.15. * |
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