KR100848722B1 - 치료용 용액, 현탁액, 또는 분산액을 재구성하기 위한 장치 - Google Patents
치료용 용액, 현탁액, 또는 분산액을 재구성하기 위한 장치 Download PDFInfo
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- KR100848722B1 KR100848722B1 KR1020027004568A KR20027004568A KR100848722B1 KR 100848722 B1 KR100848722 B1 KR 100848722B1 KR 1020027004568 A KR1020027004568 A KR 1020027004568A KR 20027004568 A KR20027004568 A KR 20027004568A KR 100848722 B1 KR100848722 B1 KR 100848722B1
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
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- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
- A61M2005/2451—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing preventing delivery before mixing is completed, e.g. by locking mechanisms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
- A61M2005/247—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with fixed or steady piercing means, e.g. piercing under movement of ampoule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
- A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
- A61M5/288—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened by piercing without internal pressure increase
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Abstract
Description
사용 전에 밀봉된 두 개의 저장조를 포함하는 몇몇의 상호 잠금 요소에 의해 구성되며 이중 팁 바늘을 통해 접속될 수 있는 주사기를 설명하는 유럽 특허 출원 제EP 298,595호가 또한 언급될 수 있다.
Claims (21)
- 일 단부는 고정 요소(27)에 의해 밀봉되며 다른 단부는 피스톤(29)에 의해 밀봉되고, 주사기 몸체의 일부를 형성하는 제1 저장조(13) 내부의 용액, 현탁액 또는 분산액 액체의 조제물을 재구성하기 위한, 피스톤에 의해 활성화되는 주사기형 장치에 있어서,상기 조제물의 고체 또는 동결 건조체(14)가 상기 주사기의 상기 제1 저장조(13) 내부의 진공 하에 미리 패킹되어 있고 상기 조제물의 액체부(12)가 상기 제1 저장조 및 상기 주사기로부터 미리 분리되고,상기 조제물의 재구성은 상기 피스톤(29) 내부로 도입된 중공 전이 요소를 사용하여 상기 제1 저장조(13)의 상기 피스톤(29)을 통해 상기 액체부(12)로 전이함으로서 수행되고, 상기 피스톤(29)은 상기 재구성의 전 및 재구성 중에 내부로 밀리는 것을 방지하는 상기 제1 저장조(13) 상의 잠금 메커니즘(16)을 갖는 것을 특징으로 하는 주사기형 장치.
- 제1항에 있어서, 상기 잠금 메커니즘(16) 뿐만 아니라 상부 및 하부 키이는 액체의 전이에 의한 작동 중에 전이 요소의 이동을 모니터하고 순환하는 것을 허용하며 저장하도록 속이 비어 있는 것을 특징으로 하는 주사기형 장치.
- 제1항 또는 제2항에 있어서, 상기 잠금 메커니즘(16)은 비활성화될 수 있는 것을 특징으로 하는 주사기형 장치.
- 제3항에 있어서, 상기 잠금 메커니즘(16)의 비활성화는 또한 상기 피스톤(29)으로부터의 상기 전이 요소의 후퇴에 대응하는 것을 특징으로 하는 주사기형 장치.
- 제1항 또는 제2항에 있어서, 상기 전이 요소는 바늘(18)인 것을 특징으로 하는 주사기형 장치.
- 제1항 또는 제2항에 있어서, 상기 액체부(12)는 상기 잠금 메커니즘(16)을 통한 주사기의 상기 제1 저장조(13) 내부로의 전이를 활성화시키는 기능을 하는 제2 저장조(11) 내에 있는 것을 특징으로 하는 주사기형 장치.
- 제1항 또는 제2항에 있어서, 상기 액체부(12) 및 고체 또는 동결 건조체(14)는 유리 튜브 또는 카트리지와 같은 제1 및 제2 저장조(13, 11) 내부에서 패킹되고,상기 장치는 일회용 또는 다회용 펜 주입기형 주사기인 것을 특징으로 하는 주사기형 장치.
- 제7항에 있어서, 상기 제2 저장조(11) 내의 상기 액체부(12)는 또한 부피에 의해 상기 조제물의 재구성된 부피를 자동 제어하는 것을 특징으로 하는 주사기형 장치.
- 제8항에 있어서, 조제물은 제2 저장조(11)의 튜브 내에서 피스톤(23)의 하강에 의해 자동으로 재구성되는 것을 특징으로 하는 주사기형 장치.
- 제1항 또는 제2항에 있어서, 주입 바늘(20)은 미리 고정되며 캡(36)은 상기 조제물의 재구성 전에 잠금 메커니즘(37)에 의해 잠금되는 것을 특징으로 하는 주사기형 장치.
- 제1 저장조(13) 내에서 움직임이 잠금된 주입 피스톤(29)에 의해 일 측면 상에서 밀봉된 원통형 제1 저장조(13) 내부의 패킹 공정에 있어서,상기 제1 저장조(13)가 상기 피스톤(23)에 의해 밀봉되기 전에 패킹될 요소가 상기 주입 피스톤(23)으로부터 상기 제1 저장조(13)의 내부로 도입되며, 상기 제1 저장조(13)는 다른 측면으로부터 미리 밀봉된 카트리지 또는 튜브(13)이고,상기 원통형 제1 저장조(13)는 지지물(19) 및 다른 지지물(19) 내에서 잠금된 상기 피스톤(29) 내부로 미리 도입됨으로써, 개구가 두 개의 지지물(19) 사이의 상기 저장조의 외부로 향하게 하고,이어서, 상기 피스톤(29)은 압력 하에서 상기 두 개의 지지물(19)을 접합시킴으서 상기 제1 저장조(13) 내부로 도입되는 것을 특징으로 하는 패킹 공정.
- 제11항에 있어서, 상기 주입 피스톤(29)에 의한 밀봉 전에 동결 건조가 수행되는 것을 특징으로 하는 패킹 공정.
- 제12항에 있어서, 상기 피스톤(29)은 대기압에 의해 제1 저장조(13) 내에 명확히 위치됨으로써, 패킹 제어를 허용하는 것을 특징으로 하는 패킹 공정.
- 제12항 또는 제13항에 있어서, 고체 또는 동결 건조체(14)가 도입되어, 동결 건조 전에 상기 제1 저장조(13)에서 층으로 개별 냉동되는 것을 특징으로 하는 패킹 공정.
- 제11항 내지 제13항 중 어느 한 항에 있어서,상기 원통형 제1 저장조는 상기 피스톤(29)이 미리 위치된 지지물(19) 내부로 미리 도입됨으로써 개구가 상기 지지물(19)을 통해 상기 제1 저장조(13)의 외부를 향하게 하고,이어서, 상기 피스톤(29)은 그것을 안내하도록 기능하는 상기 지지물(19)을 가압하에 변위시킴으로서 상기 제1 저장조(13)의 내부로 도입되는 것을 특징으로 하는 패킹 공정.
- 제12항에 있어서, 상기 지지물(19)은 이어서 주입 주사기 장치 및 그 패킹의 일부를 구성하는 것을 특징으로 하는 패킹 공정.
- 제11항 내지 제13항 중 어느 한 항에 있어서, 고체 또는 동결 건조체(14)는 저장조 내에서 매우 격렬한 방식으로 미리 교반된 혼합물인 것을 특징으로 하는 패킹 공정.
- 제11항 내지 제13항 중 어느 한 항에 있어서, 원통형 제1 저장조는 지지물(19) 및 다른 지지물(19) 내에서 고정된 피스톤(29) 내부로 미리 도입됨으로써, 개구를 두 개의 지지물(19) 사이의 상기 제1 저장조의 외부로 향하게 하고, 이어서 상기 피스톤은 압력 및 두 개의 지지물(19)을 접합시킴으로서 상기 제1 저장조 내부로 도입되는 것을 특징으로 하는 패킹 공정.
- 제18항에 있어서, 상기 지지물(19)은 상기 원통형 제1 저장조(13)의 패킹의 구성 및 접합 이후에 밀폐식으로 밀봉되는 것을 특징으로 하는 패킹 공정.
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9912748A FR2799654B1 (fr) | 1999-10-13 | 1999-10-13 | Dispositif pour reconstituer une solution, une suspension ou une dispersion therapeutique et procede de preparation et de conditionnement dans ce dispositif |
FR99/12748 | 1999-10-13 |
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KR20020042709A KR20020042709A (ko) | 2002-06-05 |
KR100848722B1 true KR100848722B1 (ko) | 2008-07-25 |
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KR1020027004568A KR100848722B1 (ko) | 1999-10-13 | 2000-10-10 | 치료용 용액, 현탁액, 또는 분산액을 재구성하기 위한 장치 |
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US (2) | US6902543B1 (ko) |
EP (1) | EP1223999B1 (ko) |
JP (1) | JP4394325B2 (ko) |
KR (1) | KR100848722B1 (ko) |
CN (1) | CN1216657C (ko) |
AR (1) | AR025958A1 (ko) |
AT (1) | ATE327789T1 (ko) |
AU (1) | AU7796400A (ko) |
CA (1) | CA2386160C (ko) |
CZ (1) | CZ302559B6 (ko) |
DE (1) | DE60028401T2 (ko) |
ES (1) | ES2261244T3 (ko) |
FR (1) | FR2799654B1 (ko) |
HK (1) | HK1050495A1 (ko) |
HU (1) | HU226437B1 (ko) |
IL (2) | IL148897A0 (ko) |
NZ (1) | NZ518286A (ko) |
PL (1) | PL203757B1 (ko) |
RU (1) | RU2258537C2 (ko) |
WO (1) | WO2001026718A1 (ko) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101559286B1 (ko) * | 2014-02-24 | 2015-10-08 | 주성 | 카트리지 장착형 주사기 |
EP3771452A1 (en) * | 2019-08-02 | 2021-02-03 | 3M Innovative Properties Company | A syringe assembly |
Families Citing this family (86)
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US6809804B1 (en) | 2000-05-11 | 2004-10-26 | Becton, Dickinson And Company | System and method for providing improved event reading and data processing capabilities in a flow cytometer |
DE10129452A1 (de) * | 2001-06-19 | 2003-01-09 | Bosch Gmbh Robert | Verfahren zum Befüllen von im wesentlichen zylinderförmigen Ampullen |
JP4112851B2 (ja) * | 2001-11-27 | 2008-07-02 | テルモ株式会社 | 2室型プレフィルドシリンジ |
GB0217285D0 (en) | 2002-07-25 | 2002-09-04 | Cambridge Consultants | Syringes |
NL1021236C2 (nl) * | 2002-08-08 | 2004-02-10 | Medical Patents Ltd | Injectiespuitsamenstel. |
JP4144027B2 (ja) * | 2002-09-11 | 2008-09-03 | ニプロ株式会社 | 2成分混合タイプのプレフィルドシリンジ |
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- 2000-10-10 AT AT00967987T patent/ATE327789T1/de not_active IP Right Cessation
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KR101559286B1 (ko) * | 2014-02-24 | 2015-10-08 | 주성 | 카트리지 장착형 주사기 |
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Also Published As
Publication number | Publication date |
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DE60028401T2 (de) | 2007-05-24 |
NZ518286A (en) | 2004-06-25 |
EP1223999B1 (fr) | 2006-05-31 |
WO2001026718A1 (fr) | 2001-04-19 |
JP4394325B2 (ja) | 2010-01-06 |
CN1378466A (zh) | 2002-11-06 |
CA2386160C (fr) | 2009-09-01 |
HUP0203515A2 (en) | 2003-03-28 |
ES2261244T3 (es) | 2006-11-16 |
US20050075602A1 (en) | 2005-04-07 |
JP2003511159A (ja) | 2003-03-25 |
CZ302559B6 (cs) | 2011-07-13 |
EP1223999A1 (fr) | 2002-07-24 |
FR2799654B1 (fr) | 2002-01-11 |
AR025958A1 (es) | 2002-12-26 |
AU7796400A (en) | 2001-04-23 |
IL148897A (en) | 2006-12-31 |
US6902543B1 (en) | 2005-06-07 |
CN1216657C (zh) | 2005-08-31 |
HK1050495A1 (en) | 2003-06-27 |
CZ20021291A3 (cs) | 2003-04-16 |
PL355150A1 (en) | 2004-04-05 |
HU226437B1 (en) | 2008-12-29 |
ATE327789T1 (de) | 2006-06-15 |
DE60028401D1 (de) | 2006-07-06 |
FR2799654A1 (fr) | 2001-04-20 |
RU2258537C2 (ru) | 2005-08-20 |
CA2386160A1 (fr) | 2001-04-19 |
PL203757B1 (pl) | 2009-11-30 |
KR20020042709A (ko) | 2002-06-05 |
IL148897A0 (en) | 2002-09-12 |
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