KR100806695B1 - 색소화 질환 치료용 세포치료 약제학적 조성물 - Google Patents
색소화 질환 치료용 세포치료 약제학적 조성물 Download PDFInfo
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- KR100806695B1 KR100806695B1 KR1020060037022A KR20060037022A KR100806695B1 KR 100806695 B1 KR100806695 B1 KR 100806695B1 KR 1020060037022 A KR1020060037022 A KR 1020060037022A KR 20060037022 A KR20060037022 A KR 20060037022A KR 100806695 B1 KR100806695 B1 KR 100806695B1
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/091—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells melanocytes
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- C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
- C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
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Abstract
Description
Claims (11)
- 멜라닌세포, 각질세포 및 섬유아세포를 유효성분으로 포함하며, 상기 섬유아세포의 수는 1 x 103 - 1 x 107 cells/cm2인 색소화 질환 (pigmentation disorders)의 치료용 세포치료 (cell therapy) 약제학적 조성물.
- 제 1 항에 있어서, 상기 멜라닌세포, 각질세포, 섬유아세포 또는 멜라닌세포, 각질세포와 섬유아세포는 체외 분리 또는 체외 분리 후 배양된 것을 특징으로 하는 색소화 질환의 치료용 세포치료 약제학적 조성물.
- 제 1 항에 있어서, 상기 색소화 질환은 저색소화증 (hypopigmentation), 부분 백피증 (piebaldism), 점상 백피증 (leukoderma), 화학물질에 의한 백피증(leukoderma), 백색 비강진 (piryriasis alba), 탈색소 모반, 염증 후 탈색증 또는 백반증인 것을 특징으로 하는 색소화 질환의 치료용 세포치료 약제학적 조성물.
- 제 1 항에 있어서, 상기 조성물에서 상기 멜라닌세포의 수는 1 x 103 - 1 x 106 cells/cm2이고, 상기 각질세포의 수는 1 x 104 - 1 x 107 cells/cm2 이고, 상기 섬유아세포의 수는 1 x 103 - 1 x 106 cells/cm2인 것을 특징으로 하는 색소화 질환의 치료용 세포치료 약제학적 조성물.
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20050113287 | 2005-11-25 | ||
KR1020050113287 | 2005-11-25 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020070110013A Division KR20070108846A (ko) | 2007-10-31 | 2007-10-31 | 색소화 질환 치료용 세포치료 약제학적 조성물 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20070055309A KR20070055309A (ko) | 2007-05-30 |
KR100806695B1 true KR100806695B1 (ko) | 2008-02-27 |
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ID=38067372
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Application Number | Title | Priority Date | Filing Date |
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KR1020060037022A KR100806695B1 (ko) | 2005-11-25 | 2006-04-25 | 색소화 질환 치료용 세포치료 약제학적 조성물 |
Country Status (3)
Country | Link |
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KR (1) | KR100806695B1 (ko) |
CN (2) | CN103356701B (ko) |
WO (1) | WO2007061168A1 (ko) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2928654B1 (fr) * | 2008-03-17 | 2018-04-27 | L'oreal | Equivalent de peau pigmentee fonctionnelle. |
CA2658074C (fr) * | 2008-03-17 | 2017-11-07 | L'oreal | Equivalent de peau pigmentee fonctionnelle |
KR101328561B1 (ko) * | 2010-05-11 | 2013-11-13 | (주) 메디컬그룹베스티안 | 피부결함의 완화 또는 치료를 위한 자가피부세포치료제의 제조방법 |
KR101431883B1 (ko) * | 2011-11-24 | 2014-08-21 | 경희대학교 산학협력단 | 동물실험 대체를 위한 3차원 인공 조직 및 모니터링 세포의 공동배양 시스템 및 이의 제조방법 |
CN103983762A (zh) * | 2013-02-08 | 2014-08-13 | 北京富龙康泰生物技术有限公司 | 含黑色素细胞的皮肤模型、其构建方法及用途 |
CN104877957B (zh) * | 2014-02-28 | 2018-06-01 | 上海尚瑞生物医药科技有限公司 | 一种促进黑色素细胞色素产生的细胞株 |
EP3200683A4 (en) * | 2014-09-29 | 2018-03-21 | ELC Management LLC | Actives for stimulating differentiation of keratinocytes to lighten hyperpigmented skin |
US20180112189A1 (en) * | 2015-03-26 | 2018-04-26 | Université De Bordeaux | Skin equivalent and use |
EP3072535B1 (fr) * | 2015-03-26 | 2017-03-01 | Université de Bordeaux | Procédé de reconstruction de peau |
CN105112353A (zh) * | 2015-07-29 | 2015-12-02 | 赫柏慧康生物科技无锡有限公司 | 角质细胞和黑素细胞混合培养的方法及应用 |
FR3054449B1 (fr) * | 2016-07-29 | 2018-08-31 | L'oreal | Equivalent de peau a compartiments dermiques juxtaposes distincts |
EP3336175B1 (en) * | 2016-12-16 | 2023-08-30 | Universite De Bordeaux | Three-dimensional model of depigmenting disorder |
JP7495354B2 (ja) * | 2018-11-30 | 2024-06-04 | 株式会社 資生堂 | 皮膚の色素沈着を治療または予防するための組成物 |
JP7522042B2 (ja) | 2018-11-30 | 2024-07-24 | 株式会社 資生堂 | 色素沈着皮膚モデルおよびその製造方法、ならびに皮膚の色素沈着を治療または予防するための因子の評価方法 |
CN110257327A (zh) * | 2019-06-27 | 2019-09-20 | 重庆市细胞生物工程技术有限公司 | 一种脐带间充质干细胞的分离培养方法 |
CN114686420B (zh) * | 2022-04-08 | 2023-11-28 | 济南磐升生物技术有限公司 | 一种3d表皮模型的制备方法及应用 |
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2006
- 2006-04-25 KR KR1020060037022A patent/KR100806695B1/ko active IP Right Grant
- 2006-06-20 WO PCT/KR2006/002366 patent/WO2007061168A1/en active Application Filing
- 2006-06-20 CN CN201310231829.8A patent/CN103356701B/zh not_active Expired - Fee Related
- 2006-06-20 CN CNA2006800503254A patent/CN101351217A/zh active Pending
Non-Patent Citations (1)
Title |
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Pigment. Cell. Res. 14, 116-125, 2001년 |
Also Published As
Publication number | Publication date |
---|---|
WO2007061168A1 (en) | 2007-05-31 |
KR20070055309A (ko) | 2007-05-30 |
CN101351217A (zh) | 2009-01-21 |
CN103356701B (zh) | 2016-08-31 |
CN103356701A (zh) | 2013-10-23 |
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