KR100767204B1 - 일회용 전기화학적 센서의 연속 제조 방법 - Google Patents
일회용 전기화학적 센서의 연속 제조 방법 Download PDFInfo
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- KR100767204B1 KR100767204B1 KR1020027012774A KR20027012774A KR100767204B1 KR 100767204 B1 KR100767204 B1 KR 100767204B1 KR 1020027012774 A KR1020027012774 A KR 1020027012774A KR 20027012774 A KR20027012774 A KR 20027012774A KR 100767204 B1 KR100767204 B1 KR 100767204B1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/002—Electrode membranes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
- C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
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- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
Description
Claims (21)
- 기판(substrate)과, 전극층(electrode layer) 및 적어도 제 1 시약층(first reagent layer)을 포함하는 전기화학적 센서 제조 방법으로서,적어도 두개의 프린트 스테이션들(33, 34, 35)을 통과하도록 상기 기판(31)의 연속적인 웹(continuous web)을 이송하는 단계와,상기 전극층(16) 및 상기 제 1 시약층(17)을 상기 기판상에 프린트하는 단계를 포함하고,상기 웹이 상기 프린트 스테이션들을 통과할 때에 상기 프린트 스테이션들 중 하나의 스테이션(33)은 상기 기판(31)의 연속적인 웹상에 상기 전극층(16)을 프린트하고, 상기 프린트 스테이션들 중 다른 스테이션(34)은 상기 기판(31)의 연속적인 웹상에 상기 제 1 시약층(17)을 프린트하는 전기화학적 센서(electrochemical sensors) 제조 방법에 있어서,상기 프린트 스테이션들(33, 34, 35)은 실린더 스크린 프린트 스테이션(cylinder screen printing stations)인 전기화학적 센서 제조 방법.
- 삭제
- 삭제
- 제 1 항에 있어서, 상기 전기화학적 센서는 포도당(glucose)을 검출하는 전기화학적 센서 제조 방법.
- 제 4 항에 있어서, 상기 제 1 시약층은 포도당 산화효소(glucose oxidase)를 포함하는 전기화학적 센서 제조 방법.
- 제 1 항, 제 4 항 또는 제 5 항 중 어느 한 항에 있어서, 상기 일회용 전기화학적 센서는 제 3 프린트 스테이션에 의해 상기 연속적인 웹 기판상에 증착되는 제 2 시약층을 부가로 포함하는 전기화학적 센서 제조 방법.
- 제 6 항에 있어서, 상기 제 2 시약층은 전자 전달 매개체(electron transfer mediator)를 포함하는 전기화학적 센서 제조 방법.
- 제 7 항에 있어서, 상기 전자 전달 매개체는 페리시아나이드(ferricyanide)인 전기화학적 센서 제조 방법.
- 제 1 항, 제 4 항 또는 제 5 항 중 어느 한 항에 있어서, 상기 전극층(16)과 상기 제 1 시약층(17)을 프린트하는 상기 프린트 스테이션들(33, 34, 35)은 분리된 별개의 프린트 스테이션인 전기화학적 센서 제조 방법.
- 제 9 항에 있어서, 상기 기판(31)의 연속적인 웹은 연속 공정에서 상기 프린트 스테이션들(33, 34, 35) 사이에서 이송되는 전기화학적 센서 제조 방법.
- 제 10 항에 있어서, 상기 기판(31)의 연속적인 웹은 상기 전극층(16)과 상기 제 1 시약층(17)을 프린트하는 상기 프린트 스테이션들(33, 34, 35) 사이에서 건조기(dryer)(36, 37, 38)를 통해 이송되는 전기화학적 센서 제조 방법.
- 제 11 항에 있어서, 상기 건조기(36, 37, 38)는 적외선 건조기인 전기화학적 센서 제조 방법.
- 제 1 항, 제 4 항 또는 제 5 항 중 어느 한 항에 있어서, 상기 전기화학적 센서의 프린팅 이후에 상기 웹에 적용되는 밀봉 후처리 단계를 부가로 포함하고, 이 밀봉 후처리 단계에서 밀봉층(81)이 상기 전기화학적 센서 위에 적용되는 전기화학적 센서 제조 방법.
- 제 13 항에 있어서, 상기 밀봉층(81)과 그 위에 상기 전기화학적 센서가 프린트되는 상기 웹은 센서의 단부를 절단함으로써 개방될 수 있는 샘플-수용 챔버를 형성하기 위해 협동하는 전기화학적 센서 제조 방법.
- 제 1 항, 제 4 항 또는 제 5 항에 있어서, 상기 전기화학적 센서의 프린팅 이후에 상기 웹에 적용되는 절단 후처리 단계를 부가로 포함하고, 이 절단 후처리 단계에서 상기 웹이 리본들로 절단되며,상기 각각의 리본은 복수의 센서를 포함하는 전기화학적 센서 제조 방법.
- 제 15 항에 있어서, 상기 각각의 리본은 5 내지 100 센서들을 포함하는 전기화학적 센서 제조 방법.
- 케이스와, 상기 케이스 내부에 배치된 리본을 포함하고, 이 리본에는 복수의 일회용 전기화학적 센서들이 제공되는 카세트로서,상기 센서들은 제 1 항, 제 4 항 또는 제 5 항 중 어느 한 항에 기재된 방법에 따라 제조되는 카세트.
- 제 17 항에 있어서, 상기 전기화학적 센서들은 포도당을 검출하기 위한 센서인 카세트.
- 삭제
- 제 1 항, 제 4 항 또는 제 5 항 중 어느 한 항에 기재된 방법에 따라 제조되는 전기화학적 센서.
- 제 20 항에 있어서, 상기 전기화학적 센서는 포도당과 같은 분석물을 검출하기 위한 센서이고,상기 방법은 기판상에 센서를 프린트하는 단계와, 밀봉층에 의해 상기 센서를 피복하는 단계를 포함하고, 상기 기판과 상기 밀봉층은 밀봉된 샘플-수용 챔버를 형성하기 위해 협동하며,상기 방법은 또한 샘플에 분석물을 도입하기 위해 상기 샘플-수용 챔버에 개구를 형성하도록 사용시에 상기 밀봉된 샘플-수용 챔버가 절단되는 단계를 포함하는 전기화학적 센서.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53759900A | 2000-03-28 | 2000-03-28 | |
US09/537,599 | 2000-03-28 | ||
PCT/US2001/010097 WO2001073109A2 (en) | 2000-03-28 | 2001-03-28 | Continuous process for manufacture of disposable electro-chemical sensor |
Publications (2)
Publication Number | Publication Date |
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KR20030010593A KR20030010593A (ko) | 2003-02-05 |
KR100767204B1 true KR100767204B1 (ko) | 2007-10-17 |
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Application Number | Title | Priority Date | Filing Date |
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KR1020027012774A KR100767204B1 (ko) | 2000-03-28 | 2001-03-28 | 일회용 전기화학적 센서의 연속 제조 방법 |
Country Status (17)
Country | Link |
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US (2) | US20030024811A1 (ko) |
EP (2) | EP1666605A1 (ko) |
JP (1) | JP2003529061A (ko) |
KR (1) | KR100767204B1 (ko) |
CN (1) | CN1283806C (ko) |
AT (1) | ATE311472T1 (ko) |
AU (2) | AU2001249601B2 (ko) |
CA (1) | CA2403646A1 (ko) |
DE (1) | DE60115462T2 (ko) |
DK (1) | DK1311702T3 (ko) |
ES (1) | ES2252212T3 (ko) |
HK (1) | HK1053151B (ko) |
IL (1) | IL151848A0 (ko) |
MX (1) | MXPA02009666A (ko) |
PL (1) | PL365243A1 (ko) |
RU (1) | RU2258922C2 (ko) |
WO (1) | WO2001073109A2 (ko) |
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AU4960101A (en) | 2001-10-08 |
EP1311702B1 (en) | 2005-11-30 |
KR20030010593A (ko) | 2003-02-05 |
AU2001249601B2 (en) | 2005-09-15 |
HK1053151A1 (en) | 2003-10-10 |
ES2252212T3 (es) | 2006-05-16 |
EP1666605A1 (en) | 2006-06-07 |
PL365243A1 (en) | 2004-12-27 |
US20040026243A1 (en) | 2004-02-12 |
ATE311472T1 (de) | 2005-12-15 |
CA2403646A1 (en) | 2001-10-04 |
MXPA02009666A (es) | 2004-07-30 |
DE60115462T2 (de) | 2006-07-20 |
WO2001073109A9 (en) | 2002-01-31 |
DE60115462D1 (de) | 2006-01-05 |
IL151848A0 (en) | 2003-04-10 |
WO2001073109A3 (en) | 2003-02-20 |
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