JPS6416761A - Manufacture of (trans)-4-phenyl-l-proline derivative - Google Patents

Manufacture of (trans)-4-phenyl-l-proline derivative

Info

Publication number
JPS6416761A
JPS6416761A JP63146690A JP14669088A JPS6416761A JP S6416761 A JPS6416761 A JP S6416761A JP 63146690 A JP63146690 A JP 63146690A JP 14669088 A JP14669088 A JP 14669088A JP S6416761 A JPS6416761 A JP S6416761A
Authority
JP
Japan
Prior art keywords
trans
phenyl
manufacture
proline derivative
proline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP63146690A
Other languages
Japanese (ja)
Other versions
JPH0832677B2 (en
Inventor
Aaru Kuroonensaaru Debitsudo
Eru Kuusutaa Poora
Eru Miyuuraa Richiyaado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of JPS6416761A publication Critical patent/JPS6416761A/en
Publication of JPH0832677B2 publication Critical patent/JPH0832677B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
JP63146690A 1987-06-15 1988-06-14 Process for producing (trans) -4-phenyl-L-proline derivative Expired - Lifetime JPH0832677B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6151187A 1987-06-15 1987-06-15
US61511 1997-10-10

Publications (2)

Publication Number Publication Date
JPS6416761A true JPS6416761A (en) 1989-01-20
JPH0832677B2 JPH0832677B2 (en) 1996-03-29

Family

ID=22036252

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63146690A Expired - Lifetime JPH0832677B2 (en) 1987-06-15 1988-06-14 Process for producing (trans) -4-phenyl-L-proline derivative

Country Status (6)

Country Link
JP (1) JPH0832677B2 (en)
CA (1) CA1333807C (en)
DE (1) DE3820230C2 (en)
FR (1) FR2616431B1 (en)
GB (1) GB2205832B (en)
IT (1) IT1218074B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103910A (en) * 1997-10-31 2000-08-15 Hoffmann-La Roche Inc. D-proline derivatives

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7659305B2 (en) 2002-10-31 2010-02-09 Pfizer Inc. Therapeutic proline derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4303662A (en) * 1980-11-24 1981-12-01 E. R. Squibb & Sons, Inc. Carboxyacyl, mercapto and acylmercapto derivatives of heterobicyclo compounds
US4337201A (en) * 1980-12-04 1982-06-29 E. R. Squibb & Sons, Inc. Phosphinylalkanoyl substituted prolines
US4501901A (en) * 1983-09-19 1985-02-26 E. R. Squibb & Sons, Inc. Method for making substituted prolines
US4588819A (en) * 1984-11-19 1986-05-13 E. R. Squibb & Sons, Inc. Process and intermediates for preparing trans-4-substituted-s-prolines

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6103910A (en) * 1997-10-31 2000-08-15 Hoffmann-La Roche Inc. D-proline derivatives
US6262089B1 (en) 1997-10-31 2001-07-17 Hoffman-La Roche Inc. D-proline derivatives
US6512001B1 (en) 1997-10-31 2003-01-28 Hoffmann-La Roche Inc. D-proline derivatives
US6740760B2 (en) 1997-10-31 2004-05-25 Hoffmann-La Roche Inc. D-proline derivatives

Also Published As

Publication number Publication date
DE3820230A1 (en) 1988-12-29
GB2205832A (en) 1988-12-21
IT8820949A0 (en) 1988-06-13
IT1218074B (en) 1990-04-12
JPH0832677B2 (en) 1996-03-29
DE3820230C2 (en) 2002-11-07
GB2205832B (en) 1991-07-17
CA1333807C (en) 1995-01-03
GB8813659D0 (en) 1988-07-13
FR2616431B1 (en) 1994-08-12
FR2616431A1 (en) 1988-12-16

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