JPS63212355A - Moisture holding lubricating viscous membrane protecting agent for condome - Google Patents
Moisture holding lubricating viscous membrane protecting agent for condomeInfo
- Publication number
- JPS63212355A JPS63212355A JP62035667A JP3566787A JPS63212355A JP S63212355 A JPS63212355 A JP S63212355A JP 62035667 A JP62035667 A JP 62035667A JP 3566787 A JP3566787 A JP 3566787A JP S63212355 A JPS63212355 A JP S63212355A
- Authority
- JP
- Japan
- Prior art keywords
- moisturizing
- water
- aqueous solution
- lubricant
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003223 protective agent Substances 0.000 title claims description 7
- 230000001050 lubricating effect Effects 0.000 title claims description 6
- 239000012528 membrane Substances 0.000 title 1
- 230000003020 moisturizing effect Effects 0.000 claims description 15
- 210000004400 mucous membrane Anatomy 0.000 claims description 13
- 239000000314 lubricant Substances 0.000 claims description 11
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 10
- 239000007864 aqueous solution Substances 0.000 claims description 10
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 7
- 229920002674 hyaluronan Polymers 0.000 claims description 7
- 229960003160 hyaluronic acid Drugs 0.000 claims description 7
- 235000017788 Cydonia oblonga Nutrition 0.000 claims description 5
- 235000011187 glycerol Nutrition 0.000 claims description 5
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 4
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 150000005846 sugar alcohols Polymers 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 3
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 claims 2
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 2
- -1 1,3 butylene alcohol Chemical compound 0.000 claims 1
- 229940058015 1,3-butylene glycol Drugs 0.000 claims 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Chemical compound CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 claims 1
- 150000007513 acids Chemical class 0.000 claims 1
- 235000019437 butane-1,3-diol Nutrition 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 230000000694 effects Effects 0.000 description 4
- 239000003755 preservative agent Substances 0.000 description 4
- 230000002335 preservative effect Effects 0.000 description 4
- 229920002683 Glycosaminoglycan Polymers 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 239000008213 purified water Substances 0.000 description 3
- 229920002385 Sodium hyaluronate Polymers 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 229940010747 sodium hyaluronate Drugs 0.000 description 2
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 2
- WCDDVEOXEIYWFB-VXORFPGASA-N (2s,3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O)[C@H](O)[C@H]1O WCDDVEOXEIYWFB-VXORFPGASA-N 0.000 description 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 1
- 229920001287 Chondroitin sulfate Polymers 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 210000002947 bartholin's gland Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229940059329 chondroitin sulfate Drugs 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000012812 general test Methods 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 229940014041 hyaluronate Drugs 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000004393 visual impairment Effects 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
(イ)産業上の利用分野
本発明はヒルアロン酸及び又はヒアルロン酸塩の水溶液
又は前記水溶液と水溶性潤滑剤の1種又は2種以上を含
有するコンドーム用保湿潤滑粘膜保護剤である。Detailed Description of the Invention (a) Industrial Application Field The present invention provides a moisturizing and lubricating mucous membrane for condoms containing an aqueous solution of hyaluronic acid and/or hyaluronate, or one or more of the aqueous solution and a water-soluble lubricant. It is a protective agent.
(ロ)従来の技術
現在市販されているコンドーム用の保湿潤滑剤にはグリ
セリン、プロピレングリコール。(b) Conventional technology Currently available moisturizing lubricants for condoms include glycerin and propylene glycol.
カルボキシビニールポリマー等親水性保湿剤の水溶液が
塗布され使用されているが、粘膜に対するペタツキ感が
生じ易く又粘膜から保湿潤滑剤へと水分がとシ込まれ又
逆に保湿潤滑剤へと水分がとり込まれこれが為コンドー
ム使用に当って粘膜を自然の状態に保つことが難かしく
、これが為の異和感が少く無く。An aqueous solution of a hydrophilic humectant such as carboxyvinyl polymer is applied and used, but it tends to cause a feeling of stickiness to the mucous membrane, and water may seep into the moisturizing lubricant from the mucous membrane, or vice versa. Because of this, it is difficult to keep the mucous membranes in their natural state when using a condom, and this causes some discomfort.
又反復使用による粘膜の疲労損傷も少くなかった。Furthermore, fatigue damage to the mucous membranes due to repeated use was not infrequent.
(19本発明の解決しようとする問題点本来女性体液は
粘膜を保護し男性の受入れに際し潤滑作用を有する自然
に分泌されるものであシ従来の市販品に於てはその組成
は体液とは殆んど組成を異にするものである。このため
コンドーム使用の際体内粘膜に変化を来たしこれがため
コンドーム使用時の自然感を保ち得なく又反復使用によ
る粘膜の損傷のためコンドーム使用の苦痛を来たす原因
にもなっていた。この為コンドーム使用に当って自然の
体液の有する自然感を損わず然かも粘膜保護炎症創復治
瘉の効果を早める作用のあることを目的とした保湿潤滑
粘膜保護剤を得んとするものである。(19 Problems to be Solved by the Present Invention) Female body fluids are naturally secreted substances that protect mucous membranes and have a lubricating effect upon reception of men. Most of them have different compositions.For this reason, when using condoms, the mucous membranes in the body change, which makes it impossible to maintain the natural feeling when using condoms, and the mucous membranes are damaged by repeated use, making condom use painful. For this reason, when using a condom, we developed a moisturizing lubricant mucosa that does not impair the natural feel of natural body fluids, but also has the effect of hastening the effect of protecting mucous membranes and speeding up inflammation and wound healing. The purpose is to obtain a protective agent.
に)問題点を解決するための手段
本発明に使用されるヒアルロン酸は分子量50万乃至2
20万のムコ多糖体と称せられるムコ多糖体の1種であ
シ人間の体内に広く分布する成分でこれが為粘膜に対す
る親和性が極めて高く又ヒルアロン酸の水溶液は極めて
特徴のある自然性の粘弾性を示し保水性も他のムコ多糖
類のコンドロイチン硫酸等生体内に含まれる成分の中に
あってヒアルロン酸は強い保水性を有して居る。特に女
性腟内液及びバルトリン腺液にはヒアルロン酸を成分と
する粘液が潤滑性を及びて分泌され男性を受入れ粘膜の
保護作用をなしているものであるこのことから自然の体
液に近い保湿潤滑剤をコンドーム使用に当シ補充使用せ
んとするものである。2) Means for solving the problems The hyaluronic acid used in the present invention has a molecular weight of 500,000 to 2.
It is a type of mucopolysaccharide called 200,000 mucopolysaccharides, and is a component widely distributed in the human body.As a result, it has an extremely high affinity for mucous membranes, and an aqueous solution of hyaluronic acid has a very unique natural viscosity. Hyaluronic acid exhibits elasticity and has strong water-retaining properties among other components found in living organisms, such as chondroitin sulfate, which is a mucopolysaccharide. In particular, female vaginal fluid and Bartholin's gland fluid secrete lubricating mucus containing hyaluronic acid, which accepts men and protects the mucous membranes.For this reason, it is a moisturizing lubrication that is close to natural body fluids. The agent is intended to be used as a supplement for condom use.
(ホ)作用と実施例
例1 保湿潤滑粘膜保護剤
ヒルアロン酸ナトリウム 0.2グリセリン
5.0
防腐剤 0.1精製水を加えて
100とする。(e) Effects and Examples Example 1 Moisturizing, lubricating, mucosal protective agent Sodium hyaluronate 0.2 Glycerin
5.0 Preservative 0.1 Add purified water to make 100.
例2
ヒルアロン酸ナトリウム 0.1グリセリン
3.0ボリアクリール酸ナトリウム
0.1防腐剤 0.1精製
水を加えて100とする。Example 2 Sodium hyaluronate 0.1 glycerin
3.0 Sodium polyacrylate
0.1 Preservative 0.1 Add purified water to make 100.
例6
ボリアクリール酸ナトリウム 0.15ヒルアロン酸
α15防腐剤
0.1精製氷を加えて100とする。Example 6 Sodium polyacrylate 0.15 hyaronic acid α15 preservative
Add 0.1 purified ice to make 100.
例4
クインスシードガム 0.02ヒルアロン
酸ナトリウム 0.2防腐剤
0.1精製水を加えて100とする。Example 4 Quince seed gum 0.02 Sodium hyaronate 0.2 Preservative
Add 0.1 purified water to make 100.
使用するクインスシードガムの規格
性状 類白色〜淡黄色の粉末 目視乾燥減量 1
2%以下 105°3hr強熱残分 15%以下
粧原基2一般試験法液性 P H4,5〜6.50
.4チ水溶液粘度 100〜s o、 o c p
s 下記性粘度i!11定法
試料2.01にイオン交換水4. OOM tを加えよ
く攪拌し溶解した液を流水中に2時間放置後20℃で粘
度を測定する。粘度計はBM型粘度計を使用し属20−
ター3ORPMで回転開始後30秒の値を読み換算係数
をかけた時の値である。Standard properties of the quince seed gum used White to pale yellow powder Visual loss on drying 1
2% or less 105°3hr ignition residue 15% or less
Cosmetic primordium 2 general test method liquid pH 4.5-6.50
.. 4. Aqueous solution viscosity 100~s o, o c p
s The following viscosity i! 11 Standard method sample 2. Add ion exchange water to 01 4. OOM t was added, stirred well, and the dissolved solution was left in running water for 2 hours, and then the viscosity was measured at 20°C. A BM type viscometer is used for the viscometer.
This is the value obtained by reading the value 30 seconds after the start of rotation at 3ORPM and multiplying it by the conversion coefficient.
各側の液0.1〜1fをコンドームに塗布又はコンドー
ム使用時局部に塗布使用するものである。0.1 to 1 f of the liquid on each side is applied to the condom or to the private parts when using the condom.
(へ)発明の効果
上記特許請求範囲によって作られた水溶液01〜1fを
コンドームに塗布又はコンドーム使用時女性局部に塗布
することによシ従来に得られなかった粘膜親和性と自然
感が得られ又反復使用時に於ける局部粘膜の損傷による
苦痛も少くコンドーム使用感を殆んど感じさせなくする
ことが出来たものである。(f) Effects of the invention By applying the aqueous solutions 01 to 1f prepared according to the above claims to a condom or to a woman's private parts when using a condom, mucosal affinity and a natural feeling that could not be obtained in the past can be obtained. Furthermore, there is less pain due to damage to the local mucous membranes during repeated use, and the condom can be used so that the user hardly feels the sensation of using it.
Claims (1)
溶液と水溶性保湿潤滑剤の1種又は2種以上を含有する
ヒルアロン酸濃度0.01乃至3重量%濃度の含有した
液を特徴とするコンドーム用保湿粘膜保護剤 2、水溶性保湿潤滑剤がグリセリン、1,3ブチレンア
ルコール、ポリビニールアルコール、の如き高級アルコ
ール、並びに多価アルコール又は高分子多価アルコール
並びにこれ等の水溶液である特許請求の範囲第1項記載
のコンドーム用保湿潤滑粘膜保護剤 3、水溶性保湿潤滑剤がポリアクリル酸ナトリウム、カ
ルボキシメチールポリマーの如き高分子酸及びその塩類
である特許請求の範囲第1項記載のコンドーム用保湿潤
滑粘膜保護剤 4、水溶性保湿潤滑剤がマルメロの種子から抽出精製し
たクィンスシードガム及びその水溶液である特許請求の
範囲第1項記載のコンドーム用保湿潤滑粘膜保護剤 5、水溶性保湿潤滑剤がグリセリン、1,3ブチレング
リコール、ポリビニールアルコール。ポリアクリル酸ナ
トリウム、カルボン酸エチールポリマー、の如き多価ア
ルコール、高分子多価アルコール、及び高分子の酸及び
その塩類又クインスシードガムの1種又は2種以上の使
用されたものである特許請求の範囲第1項記載のコンド
ーム用保湿潤滑粘膜保護剤[Scope of Claims] 1. An aqueous solution of hyaluronic acid and/or its salts, or a liquid containing hyaluronic acid at a concentration of 0.01 to 3% by weight, which contains the aqueous solution and one or more water-soluble moisturizing lubricants. Moisturizing mucosal protective agent for condoms 2, characterized in that the water-soluble moisturizing lubricant is a higher alcohol such as glycerin, 1,3 butylene alcohol, polyvinyl alcohol, polyhydric alcohol or high molecular weight polyhydric alcohol, and an aqueous solution thereof. The moisturizing lubricant mucous membrane protectant 3 for condoms according to claim 1, wherein the water-soluble moisturizing lubricant is a polymeric acid such as sodium polyacrylate or carboxymethyl polymer and its salts. Moisturizing and lubricating mucosal protective agent for condoms according to claim 1, wherein the water-soluble moisturizing lubricant is quince seed gum extracted and purified from quince seeds and its aqueous solution. Agent 5: The water-soluble moisturizing lubricant is glycerin, 1,3-butylene glycol, and polyvinyl alcohol. Patents that use one or more of polyhydric alcohols such as sodium polyacrylate, ethyl carboxylate polymers, polymeric polyhydric alcohols, polymeric acids and their salts, or quince seed gum. Moisturizing lubricant mucosal protective agent for condoms according to claim 1
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62035667A JPS63212355A (en) | 1987-02-20 | 1987-02-20 | Moisture holding lubricating viscous membrane protecting agent for condome |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62035667A JPS63212355A (en) | 1987-02-20 | 1987-02-20 | Moisture holding lubricating viscous membrane protecting agent for condome |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS63212355A true JPS63212355A (en) | 1988-09-05 |
Family
ID=12448225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62035667A Pending JPS63212355A (en) | 1987-02-20 | 1987-02-20 | Moisture holding lubricating viscous membrane protecting agent for condome |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS63212355A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05294825A (en) * | 1992-04-17 | 1993-11-09 | Okamoto Ind Inc | Lubricant |
WO1996003973A1 (en) * | 1994-08-01 | 1996-02-15 | Lifegroup S.P.A. | Highly bioadhesive and mucoadhesive compositions for the treatmenof epithelia and mucous membranes |
WO2008011088A3 (en) * | 2006-07-20 | 2008-06-12 | Allegiance Corp | Nonaqueous coating composition for elastomeric articles and articles containing the same |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS601110A (en) * | 1983-04-28 | 1985-01-07 | Ajinomoto Co Inc | Moisturizing agent |
JPS613500A (en) * | 1984-06-15 | 1986-01-09 | 二國機械工業株式会社 | Device for protecting cable drawing unit |
-
1987
- 1987-02-20 JP JP62035667A patent/JPS63212355A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS601110A (en) * | 1983-04-28 | 1985-01-07 | Ajinomoto Co Inc | Moisturizing agent |
JPS613500A (en) * | 1984-06-15 | 1986-01-09 | 二國機械工業株式会社 | Device for protecting cable drawing unit |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05294825A (en) * | 1992-04-17 | 1993-11-09 | Okamoto Ind Inc | Lubricant |
WO1996003973A1 (en) * | 1994-08-01 | 1996-02-15 | Lifegroup S.P.A. | Highly bioadhesive and mucoadhesive compositions for the treatmenof epithelia and mucous membranes |
US5876744A (en) * | 1994-08-01 | 1999-03-02 | Lifegroup S.P.A. | Highly bioadhesive and mucoadhesive compositions containing polyvinyl alcohol, polycarbophil and biopolymer for the treatment of skin conditions and as vehicles for active ingredients |
WO2008011088A3 (en) * | 2006-07-20 | 2008-06-12 | Allegiance Corp | Nonaqueous coating composition for elastomeric articles and articles containing the same |
JP2013154194A (en) * | 2006-07-20 | 2013-08-15 | Allegiance Corp | Nonaqueous coating composition for elastomeric article and article containing the same |
JP2015231567A (en) * | 2006-07-20 | 2015-12-24 | アレジアンス、コーポレイション | Nonaqueous coating composition for elastomeric article and article containing the same |
EP3542831A1 (en) * | 2006-07-20 | 2019-09-25 | Allegiance Corporation | Nonaqueous coating composition for elastomeric articles and articles containing the same |
EP3838303A1 (en) * | 2006-07-20 | 2021-06-23 | Allegiance Corporation | Nonaqueous coating composition for elastomeric articles and articles containing the same |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Wynne et al. | An effective, cosmetically acceptable, novel hydro-gel emollient for the management of dry skin conditions | |
JPH01305012A (en) | Skin humidifying composition and production thereof | |
CN103083733A (en) | Medical water-based lubricant for introducing instrument into body cavity | |
JPS647043B2 (en) | ||
WO2020073966A1 (en) | Water-soluble lubricant, and preparation method and use therefor | |
CN106619489A (en) | Temperature-sensitive gel for skin injury and preparation method of temperature-sensitive gel | |
JPS6110504A (en) | Cosmetic composition | |
JPS61180705A (en) | Cosmetic | |
US5690945A (en) | Cosmetic skin-cleansing mask compositions containing graded spheroidal polyamide particles | |
CN101332317A (en) | Water soluble human lubricant | |
CN115317427A (en) | Anti-inflammatory repairing composition and preparation method and application thereof | |
US8071076B2 (en) | Oral lubricating and stain retarding compositions | |
JPS63212355A (en) | Moisture holding lubricating viscous membrane protecting agent for condome | |
CN113332160A (en) | Cosmetic composition for conditioning peritrichotic skin | |
CN104840958A (en) | Artificial mucosa composition as well as preparation method and application thereof | |
CN1544100A (en) | Water-soluble human body lubricant | |
CN102989045A (en) | Biocompatible water-soluble composition and use thereof | |
JP3990541B2 (en) | Gel-like composition for moisturizing | |
JPH02311408A (en) | Gel-like composition for skin | |
JPS62209010A (en) | Cosmetic | |
CN114569629A (en) | Composition for removing scar and repairing skin and preparation method thereof | |
CN101130116A (en) | Natural lubricant for condom | |
CA2000277A1 (en) | Treatment of periodontal disease | |
CN1083359A (en) | Human body lubricants | |
CN106730042A (en) | A kind of preparation method of low-residual hyaluronic acid matrix human body lubricants |