JPS5955815A - Promotor for hair growth - Google Patents

Promotor for hair growth

Info

Publication number
JPS5955815A
JPS5955815A JP57168175A JP16817582A JPS5955815A JP S5955815 A JPS5955815 A JP S5955815A JP 57168175 A JP57168175 A JP 57168175A JP 16817582 A JP16817582 A JP 16817582A JP S5955815 A JPS5955815 A JP S5955815A
Authority
JP
Japan
Prior art keywords
hair growth
promotor
karasu
hair
extract
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57168175A
Other languages
Japanese (ja)
Other versions
JPH0212446B2 (en
Inventor
Michitoku Kubo
道徳 久保
Masanori Fukui
正紀 福井
Terukazu Kuwano
桑野 輝一
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIPPON FUNMATSU YAKUHIN KK
Daiichi Pharmaceutical Co Ltd
Original Assignee
NIPPON FUNMATSU YAKUHIN KK
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIPPON FUNMATSU YAKUHIN KK, Daiichi Pharmaceutical Co Ltd filed Critical NIPPON FUNMATSU YAKUHIN KK
Priority to JP57168175A priority Critical patent/JPS5955815A/en
Publication of JPS5955815A publication Critical patent/JPS5955815A/en
Publication of JPH0212446B2 publication Critical patent/JPH0212446B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

PURPOSE:A promotor for hair growth having high safety, especially effect at early stage of hair growth, containing polygoni multiflori radix or its essence. CONSTITUTION:A promotor for hair growth containing 0.5-5wt% polygoni multiflori radix or its essence. This promotor for hair growth has high safety even by long-term containous use, and may be applied in any dosage form of external use such as clcohol lotion, milky lotion, cream, etc.

Description

【発明の詳細な説明】 又は何首烏エキスを含有する発毛促進剤に関する。[Detailed description of the invention] Or, it relates to a hair growth promoter containing Heshu Karasu extract.

−・般に発毛促進剤として使用される物質は。-What are the substances commonly used as hair growth promoters?

優れた主目的効果を呈するとともに比較的長期間にわた
り連用することから,特に安全性が高いことが要求され
る。
Because they exhibit excellent primary effects and can be used continuously for a relatively long period of time, they are required to be particularly safe.

本発明者等は.上述の効果を呈する物質の探索研究をな
した結果,古来より低下した肝及び腎機能を回復さーす
る働きにより滋養強壮剤として用いられてきた何首烏が
この目的にかなうことを見出し本発明を完成した。
The present inventors. As a result of searching for a substance that exhibits the above-mentioned effects, the present invention was completed after discovering that Heku-gu-wu, which has been used as a nutritional tonic since ancient times due to its ability to restore deteriorated liver and kidney functions, satisfies this purpose. did.

本発明の優れた発毛効果は何首烏エギスをアルコール水
溶液に溶解したものを検体とし.これを除毛クリームで
脱毛したddY系雄性ラットの腹部に2週間塗布した結
果確認した。
The excellent hair growth effect of the present invention can be demonstrated by using a sample prepared by dissolving Hekubi Karasu Egisu in an alcohol aqueous solution. This was confirmed by applying it to the abdomen of male ddY rats that had been depilated with hair removal cream for two weeks.

即ち,何首烏塗布群は対照群(アルコール水溶液のみ)
と比較し,塗布初期から発毛がみられ数日後において有
意に発毛促進効果が認められた。本発明の発毛促進剤は
発毛初期での効果が特に顕著であり,新規発毛促進剤と
して有用なものである。
In other words, the Heshu Karasu application group is the control group (alcohol aqueous solution only).
In comparison, hair growth was observed from the early stage of application, and a significant hair growth promoting effect was observed several days later. The hair growth promoter of the present invention is particularly effective in the early stages of hair growth, and is useful as a new hair growth promoter.

本発明の発毛促進剤の実施に際しては.何首烏エキス末
ヲ配合したアルコールローション。
When implementing the hair growth promoter of the present invention. An alcoholic lotion containing the powdered crow extract.

乳液,クリーム等の外用剤型のいずれを採用してもよく
,これ等は常法に従って製することができる。これ等外
用剤に含有させる何首烏エキスの含量は約肌1%〜lO
%,好ましくは0.5〜5%が考えられる。
Any form of external preparation such as emulsion or cream may be used, and these can be prepared according to conventional methods. The content of Heshugarasu extract contained in these external preparations is about 1% to 100% of the skin.
%, preferably from 0.5 to 5%.

以下,試験例及び処方例をもって本発明を説明する。The present invention will be explained below using test examples and prescription examples.

試験例 何首烏エキス(日本粉末薬品製,1重量部の何亡7烏を
3.il【fjt部の50%アル]−ルで抽出したちσ
〕)を50%アルコールに溶解した検液(何鉢烏エキス
含h15%)を興ず。
Test Example Hekushu Karasu Extract (manufactured by Nippon Powder Pharmaceutical Co., Ltd., 1 part by weight of Heshu7 Karasu was extracted with 3.il [50% alcohol of fjt part]).
])) dissolved in 50% alcohol (contains 15% crow extract).

一方、実lゆ動物としてddY系雄性ラットを選びその
腹部を除毛クリームで脱毛し、脱毛部に検液を1[11
回141]間塗布した。
On the other hand, select a male ddY rat as a live animal, remove hair from its abdomen with hair removal cream, and apply 1 [11
It was applied for 141 times.

発毛促進効果は発毛スコアーを次のように設定し] (
1匹の平Jθ値を指標としてfP価した1、スコアー設
定 0  発毛みられず 1  発毛している 2  硬毛がはえそろう 8  硬毛の長さが正常型の約半分 4・  正常型の状郭 実hカ結果 図1に示す如く対照群(n = ] 0 )に苅し塗布
?!Y(n −1,n )は有意に発毛促進効果を呈し
た。
The hair growth promotion effect is determined by setting the hair growth score as follows] (
The fP value was calculated using the average Jθ value of one animal as an index, and the score was set to 0. No hair growth 1. Hair growth 2. Terminal hair is growing out 8. Terminal hair length is about half of the normal type 4. Normal As shown in Figure 1, the control group (n = ] 0) was coated with a brush. ! Y(n −1,n ) exhibited a significant hair growth promoting effect.

処方例1  アルコールローション 何首烏エギス     5.0 95%エタノール  50−0 精製水       4!5・0 処方例2  クリーム 何首烏エキス     5.0 プロピレングリコール 3・0 ザラシミツロウ    3.0 流動パラフィン   40.0 ポリオキシエチレン セヂルエーデル    3.0 千ノステアリン酸ソル ビタン        2.0 精製水       44..0 処方例3  乳液 何首烏エキス     5.0 ワセリン        3.0 流動パラフィン   10.0 グリセリン      3.0 プロピレングリコール 5.0 ポリオキシエチレンモノ オレイン酸エステル  2.0 精製水       72.0Prescription example 1 Alcohol lotion How many crows Egisu 5.0 95% ethanol 50-0 Purified water 4!5.0 Prescription example 2 Cream Hekubi Karasu Extract 5.0 Propylene glycol 3.0 Rough beeswax 3.0 Liquid paraffin 40.0 polyoxyethylene Sejiru Edel 3.0 Sennostearic acid sol Bitan 2.0 Purified water 44. .. 0 Prescription example 3 Emulsion Hekubi Karasu Extract 5.0 Vaseline 3.0 Liquid paraffin 10.0 Glycerin 3.0 Propylene glycol 5.0 polyoxyethylene mono Oleic acid ester 2.0 Purified water 72.0

【図面の簡単な説明】[Brief explanation of drawings]

図】は本発明物質の発毛効果を経時点に示したものであ
り、実線は塗布ffYのスコアーの平均値を示し1点線
は対照ttVのスコアーの平均値を示す。
The figure shows the hair growth effect of the substance of the present invention over time, where the solid line shows the average score of applied ffY and the one-dot line shows the average score of control ttV.

Claims (1)

【特許請求の範囲】[Claims] 何?7烏又は何首烏エキスを含有する発毛促進剤what? Hair growth promoter containing 7-karasu or heku-karasu extract
JP57168175A 1982-09-27 1982-09-27 Promotor for hair growth Granted JPS5955815A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP57168175A JPS5955815A (en) 1982-09-27 1982-09-27 Promotor for hair growth

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57168175A JPS5955815A (en) 1982-09-27 1982-09-27 Promotor for hair growth

Publications (2)

Publication Number Publication Date
JPS5955815A true JPS5955815A (en) 1984-03-31
JPH0212446B2 JPH0212446B2 (en) 1990-03-20

Family

ID=15863180

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57168175A Granted JPS5955815A (en) 1982-09-27 1982-09-27 Promotor for hair growth

Country Status (1)

Country Link
JP (1) JPS5955815A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020025358A (en) * 2000-09-28 2002-04-04 이 행 우 Composition for growing hair and method of preparation thereof
JP2014522832A (en) * 2012-05-29 2014-09-08 ビョンスン ノ Hair growth promoter and production method
WO2016101259A1 (en) * 2014-12-26 2016-06-30 L'oreal Process for preventing or treating hair graying comprising applying a plant extract comprising (e) -2, 3, 5, 4' -tetrahydroxy stilbene-2-o-glucoside and use thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20020025358A (en) * 2000-09-28 2002-04-04 이 행 우 Composition for growing hair and method of preparation thereof
JP2014522832A (en) * 2012-05-29 2014-09-08 ビョンスン ノ Hair growth promoter and production method
WO2016101259A1 (en) * 2014-12-26 2016-06-30 L'oreal Process for preventing or treating hair graying comprising applying a plant extract comprising (e) -2, 3, 5, 4' -tetrahydroxy stilbene-2-o-glucoside and use thereof

Also Published As

Publication number Publication date
JPH0212446B2 (en) 1990-03-20

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