JPS59219B2 - 人工歯、人工骨及びその製造方法 - Google Patents

人工歯、人工骨及びその製造方法

Info

Publication number
JPS59219B2
JPS59219B2 JP51066217A JP6621776A JPS59219B2 JP S59219 B2 JPS59219 B2 JP S59219B2 JP 51066217 A JP51066217 A JP 51066217A JP 6621776 A JP6621776 A JP 6621776A JP S59219 B2 JPS59219 B2 JP S59219B2
Authority
JP
Japan
Prior art keywords
bones
artificial
teeth
composite material
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51066217A
Other languages
English (en)
Other versions
JPS52149895A (en
Inventor
恒夫 日高
正秀 井上
正臣 蛯原
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pentax Corp
Original Assignee
Asahi Kogaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kogaku Kogyo Co Ltd filed Critical Asahi Kogaku Kogyo Co Ltd
Priority to JP51066217A priority Critical patent/JPS59219B2/ja
Priority to GB23593/77A priority patent/GB1550330A/en
Priority to DE2725665A priority patent/DE2725665B2/de
Publication of JPS52149895A publication Critical patent/JPS52149895A/ja
Priority to US05/966,233 priority patent/US4230455A/en
Publication of JPS59219B2 publication Critical patent/JPS59219B2/ja
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30965—Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/447—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on phosphates, e.g. hydroxyapatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
    • A61F2002/30009—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in fibre orientations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30907—Nets or sleeves applied to surface of prostheses or in cement
    • A61F2002/30909—Nets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0028—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in fibre orientations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Ceramic Engineering (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Manufacturing & Machinery (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dentistry (AREA)
  • Structural Engineering (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Dental Preparations (AREA)
  • Dental Prosthetics (AREA)

Description

【発明の詳細な説明】 本発明は、優れた生体親和性を有し、且つ機械的強度に
富む人工歯、人工骨及びその製造方法に関する。
水酸化アパタイトＣａ１０（ＰＯ４）６（ＯＨ）２の焼
結体は近年その優れた生体親和性が注目され、人工歯お
よび人工骨への応用が期待されている。
しかしながら通常の焼結あるいはホット・プレスによつ
て作られた材料は巨視的にみると、力学的な等方性を有
しているために歯や骨等の人体硬組織の特徴である繊維
状構造等の方向性を持たせることができない。本発明は
このような点に着目し、繊維状構造材料と水酸化アパタ
イトとで複合材料を作ることにより、生体親和性とあわ
せて機械的強度に優れた人工歯、人工骨及びその製造方
法に関するものである。本発明の実施態様は次の通りで
ある。
金属、セラミクス、あるいはガラスの繊維、あるいは細
線、またはウィスカーを成形せんとする型の中に配置し
、その周りに水酸化アパタイトの十分微細な粉末を必要
に応じてバインダーと共につめこみ、予め金属型にて冷
間圧縮成形する。この予備成形はラバー・プレスによつ
ても可能である。
水酸化アパタイト粉末と繊維材料との構成の例を第１図
、第２図、第３図に示す。図において１は粉末水酸化ア
パタイト、２は繊維材料であり、第１図は本発明を人工
歯に応用した例であり、第２図、第３図は人工骨への応
用の例である。
第３図においては繊維材料を布状に二次元的に配置した
ものである。予備成型された材料を真空中、空気中、水
蒸気雰囲気中、あるいは不活性ガス雰囲気中で温度８０
０′Ｃ〜１５００℃にて１５分〜４０時間加熱焼結する
。水酸化アパタイトと組みあわせる繊維材料については
、その熱膨張係数が水酸化アパタイトのそれと略等しい
か稍々小さいものを選べば、機械的強度はさらに改善さ
れる。
なお、水酸化アパタイトは純粋に１００％水酸化アパタ
イトである必要はなく、Ｃａ１０（ＰＯ４）６（ＯＨ）
２を５０〜１００％に対し、Ｃａ３（ＰＯ４）２、Ａｌ
ＰＯ４３Ａｌ２Ｏ３、ＡｌＦ３、ＳｉＯ２、およびＬｉ
、Ｎａ３Ｋａ３Ｃａ、Ｍｇのフッ化物、塩化物、酸化物
のうちから選ばれた一種、もしくは二種以上が０．１〜
５０％添加された出発原料も含む種以下にその効果につ
いて述べる。
本発明による複合材料は、その表面が水酸化アパタイト
であるために、アルミナ等の現用医科歯科材料と異なり
、生体親和性に優れている。その上、内部に繊維状構造
物が入つているために、圧縮強度、曲げ強度が強く、人
工歯および人工骨として充分その機能を満たすことがで
きる。
【図面の簡単な説明】
第１図は本発明による人工歯の概略図。

Claims (1)

  1. 【特許請求の範囲】 １ 金属、セラミック、ガラス繊維或はウィスカー等を
    芯材とし、Ｃａ＿１＿０（ＰＯ＿４）＿６（ＯＨ）＿２
    を５０％以上含んだ焼結体によつて形成されたことを特
    徴とする人工歯、人工骨。 ２ Ｃａ＿１＿０（ＰＯ＿４）＿６（ＯＨ）＿２を５０
    ％以上含んだ充分微細な粉末を焼結するに際し、芯材と
    して金属、セラミック、ガラス繊維或はウィスカー等を
    成形せんとする型の中に入れ、周囲に上記粉末を詰め込
    み予備成形し、次いでこの材料を加熱焼成することによ
    り人工歯、人工骨を得ることを特徴とする人工歯、人工
    骨の製造方法。
JP51066217A 1976-06-07 1976-06-07 人工歯、人工骨及びその製造方法 Expired JPS59219B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP51066217A JPS59219B2 (ja) 1976-06-07 1976-06-07 人工歯、人工骨及びその製造方法
GB23593/77A GB1550330A (en) 1976-06-07 1977-06-03 Process for producing prosthetic teeth and bones
DE2725665A DE2725665B2 (de) 1976-06-07 1977-06-06 Verfahren zur Herstellung von Zahn- und Knochenprothesen aus einer keramischen Grundmasse und anorganischem Fasermaterial
US05/966,233 US4230455A (en) 1976-06-07 1978-12-04 Prosthetic teeth and bones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP51066217A JPS59219B2 (ja) 1976-06-07 1976-06-07 人工歯、人工骨及びその製造方法

Publications (2)

Publication Number Publication Date
JPS52149895A JPS52149895A (en) 1977-12-13
JPS59219B2 true JPS59219B2 (ja) 1984-01-05

Family

ID=13309432

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51066217A Expired JPS59219B2 (ja) 1976-06-07 1976-06-07 人工歯、人工骨及びその製造方法

Country Status (4)

Country Link
US (1) US4230455A (ja)
JP (1) JPS59219B2 (ja)
DE (1) DE2725665B2 (ja)
GB (1) GB1550330A (ja)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
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FR2460657A1 (fr) * 1979-07-12 1981-01-30 Anvar Implant biodegradable utilisable comme piece de prothese osseuse
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FR2485504A1 (fr) * 1980-06-30 1981-12-31 Centre Nat Rech Scient Nouveau materiau fritte, sa preparation et son application a la realisation de prothese osseuse
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DE3225826A1 (de) * 1982-07-09 1984-01-12 Heyl Chemisch-pharmazeutische Fabrik GmbH & Co KG, 1000 Berlin Ringartiges hautimplantat und ein verfahren zu dessen herstellung
JPS5957971A (ja) * 1982-10-30 1984-04-03 株式会社イナックス 鉱物系繊維−アパタイト系焼成複合体
US4503157A (en) * 1982-09-25 1985-03-05 Ina Seito Co., Ltd. Sintered apatite bodies and composites thereof
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JPS59153832U (ja) * 1983-04-01 1984-10-16 黒田電気株式会社 缶ビ−ル用把手
JPS59189842A (ja) * 1983-04-08 1984-10-27 アイシン精機株式会社 遠心分散成形による複合インプラント材の製造方法
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US5273941A (en) * 1988-01-30 1993-12-28 Ibiden Co., Ltd. Fiber reinforced silicon carbide ceramics and method of producing the same
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US5091344A (en) * 1988-01-30 1992-02-25 Ibiden Corporation Fiber reinforced ceramics of calcium phosphate series compounds and method of producing the same
US5082808A (en) * 1988-07-04 1992-01-21 Tdk Corporation Ceramic material and method for making
US4936776A (en) * 1988-07-05 1990-06-26 Kwiatkowski Stephen J Dental product and method utilizing translucent material
US5534031A (en) * 1992-01-28 1996-07-09 Asahi Kogaku Kogyo Kabushiki Kaisha Prosthesis for spanning a space formed upon removal of an intervertebral disk
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EP0914072B1 (en) * 1997-03-04 2004-05-19 Technology Finance Corporation (Proprietary) Limited An artefact suitable for use as a bone implant
JP3360810B2 (ja) 1998-04-14 2003-01-07 ペンタックス株式会社 骨補填材の製造方法
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JP4540905B2 (ja) * 2001-11-13 2010-09-08 Ｈｏｙａ株式会社 焼結体の製造方法
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