JPS5785319A - Agent for dental caries - Google Patents

Agent for dental caries

Info

Publication number
JPS5785319A
JPS5785319A JP55161091A JP16109180A JPS5785319A JP S5785319 A JPS5785319 A JP S5785319A JP 55161091 A JP55161091 A JP 55161091A JP 16109180 A JP16109180 A JP 16109180A JP S5785319 A JPS5785319 A JP S5785319A
Authority
JP
Japan
Prior art keywords
agent
extract
koboku
magnolol
honokiol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP55161091A
Other languages
Japanese (ja)
Other versions
JPH0138084B2 (en
Inventor
Tsuneo Nanba
Yukio Hattori
Masago Kyozuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TSURUI YAKUHIN KOGYO KK
Original Assignee
TSURUI YAKUHIN KOGYO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TSURUI YAKUHIN KOGYO KK filed Critical TSURUI YAKUHIN KOGYO KK
Priority to JP55161091A priority Critical patent/JPS5785319A/en
Publication of JPS5785319A publication Critical patent/JPS5785319A/en
Publication of JPH0138084B2 publication Critical patent/JPH0138084B2/ja
Granted legal-status Critical Current

Links

Abstract

PURPOSE: To provide an agent for preventing or inhibiting the progress of dental caries and containing the extract of KOBOKU (bark of Magnolia officinalis REHD. et WILS.), OREN (rhizome of Coptis chinensis FRANCH.) etc. or magnolol and honokiol which are the active components of the above extract.
CONSTITUTION: The objective agent contains the extract of KOBOKU, OREN, GOBAISHI (gall of Rhus chinensis MILL), GENNOSHOKO (whole grass of Geranium thunbergii SIEB. et ZUCC.), OBAKU (bark of Phellodendron amurense RUPR.), etc. and/or their active components (e.g. magnolol or formula I, honokiol of formula II, berberine, etc.). The agent inhibits remarkably the growth of Streptomyces mutans which is a cariogenic bacterium having the strongest cariogenicity. The agent has somewhat milder activity than erythromycin, and lower side effects than antibiotic substances, and is suitable for administration for a long period. It also exhibits remarkable effect at a low concentration in a short time. Administered directly in the oral cavity, or by mixing with tooth paste, or in the form of troche or sublingual tablet.
COPYRIGHT: (C)1982,JPO&Japio
JP55161091A 1980-11-16 1980-11-16 Agent for dental caries Granted JPS5785319A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55161091A JPS5785319A (en) 1980-11-16 1980-11-16 Agent for dental caries

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55161091A JPS5785319A (en) 1980-11-16 1980-11-16 Agent for dental caries

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP18217988A Division JPH01151512A (en) 1988-07-21 1988-07-21 Preventive agent for dental caries

Publications (2)

Publication Number Publication Date
JPS5785319A true JPS5785319A (en) 1982-05-28
JPH0138084B2 JPH0138084B2 (en) 1989-08-11

Family

ID=15728433

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55161091A Granted JPS5785319A (en) 1980-11-16 1980-11-16 Agent for dental caries

Country Status (1)

Country Link
JP (1) JPS5785319A (en)

Cited By (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58121218A (en) * 1982-01-07 1983-07-19 Rooto Seiyaku Kk Tooth decay preventive
JPS5995229A (en) * 1982-11-24 1984-06-01 Tsumura Juntendo Inc Novel hydroxybiphenyl compound
EP0227108A2 (en) 1985-12-27 1987-07-01 Lion Corporation Oral composition
JPS62205016A (en) * 1986-03-05 1987-09-09 Sankin Kogyo Kk Denture cleaner
JPH04346933A (en) * 1991-05-24 1992-12-02 Pokka Corp Multiplication inhibitor against dental caries fungus and pathogenic fungus of periodontal disease
JPH09143084A (en) * 1995-11-27 1997-06-03 Heetee Seika Kk Preparation of anti-tooth caries agent and anti-tooth cariesfood using this
WO1998006377A1 (en) * 1996-08-12 1998-02-19 The Procter & Gamble Company Oral compositions
WO1998006414A1 (en) * 1996-08-12 1998-02-19 The Procter & Gamble Company Oral compositions comprising honeysuckle flowers and/or goldthread extracts
WO2000067707A1 (en) * 1999-05-06 2000-11-16 Yuzo Tsuchida Cleansers containing kumazasa extract
JP2002020253A (en) * 2000-07-05 2002-01-23 Kobayashi Pharmaceut Co Ltd Composition for oral use
WO2001085116A3 (en) * 2000-05-10 2002-05-23 Colgate Palmolive Co Synergistic antiplaque/antigingivitis oral composition
KR100407651B1 (en) * 2000-12-11 2003-12-01 최동성 Novel use of functional Coptis chinensis Franch extract and process for preparation thereof
US6702999B2 (en) 2001-05-15 2004-03-09 The Procter & Gamble Co. Oral care compositions
US6703000B2 (en) 2001-05-15 2004-03-09 The Procter & Gamble Co. Confectionery compositions
US6706256B2 (en) 2001-05-15 2004-03-16 The Procter & Gamble Co. Oral care compositions
US6726897B2 (en) 2001-05-15 2004-04-27 The Procter & Gamble Co. Confectionery compositions
US6730291B2 (en) 2001-05-15 2004-05-04 The Procter & Gamble Co. Confectionery compositions
WO2003099110A3 (en) * 2002-05-28 2004-06-17 Univ California Herbs and herbal combinations useful for the treatment of microbial infections
WO2005009454A1 (en) * 2003-07-29 2005-02-03 Hououdou Co., Ltd. Periodontal disease therapeutic and/or preventive composition
JP2005162697A (en) * 2003-12-04 2005-06-23 Lotte Co Ltd Methioninase inhibitor and oral cavity composition, food and drink containing the same
WO2007011504A1 (en) * 2005-07-14 2007-01-25 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product comprising a magnolia bark extract and surfactant
WO2007126651A3 (en) * 2006-03-29 2008-03-13 Wrigley W M Jun Co Breath freshening and oral cleansing products with synergistic combinations of magnolia bark extract and essential oils
US7347985B2 (en) * 2002-06-25 2008-03-25 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract
JP2013520518A (en) * 2010-02-24 2013-06-06 コルゲート・パーモリブ・カンパニー Oral care composition
JP2013532684A (en) * 2010-07-29 2013-08-19 コルゲート・パーモリブ・カンパニー Phosphate-free oral care composition based on magnolia-derived antibacterial agent
JP2014505077A (en) * 2011-01-31 2014-02-27 コルゲート・パーモリブ・カンパニー Oral care composition
JP2015030701A (en) * 2013-08-02 2015-02-16 有限会社漢方歯科医学研究所 Antibacterial composition for oral cavity
JP2018052969A (en) * 2017-11-29 2018-04-05 有限会社漢方歯科医学研究所 Antibacterial composition for oral cavity
CN115944572A (en) * 2023-02-07 2023-04-11 湖南天华医药生物科技有限公司 Toothpaste based on nutgall extract and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5683416A (en) * 1979-12-11 1981-07-08 Lion Corp Composition for oral cavity
JPS5756415A (en) * 1980-09-20 1982-04-05 Lion Corp Composition for oral cavity
JPS5758610A (en) * 1980-09-26 1982-04-08 Lion Corp Composition for oral cavity
JPS5758612A (en) * 1980-09-26 1982-04-08 Lion Corp Composition for oral cavity application

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5683416A (en) * 1979-12-11 1981-07-08 Lion Corp Composition for oral cavity
JPS5756415A (en) * 1980-09-20 1982-04-05 Lion Corp Composition for oral cavity
JPS5758610A (en) * 1980-09-26 1982-04-08 Lion Corp Composition for oral cavity
JPS5758612A (en) * 1980-09-26 1982-04-08 Lion Corp Composition for oral cavity application

Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58121218A (en) * 1982-01-07 1983-07-19 Rooto Seiyaku Kk Tooth decay preventive
JPH0217525B2 (en) * 1982-01-07 1990-04-20 Rohto Pharma
JPS5995229A (en) * 1982-11-24 1984-06-01 Tsumura Juntendo Inc Novel hydroxybiphenyl compound
JPH0463054B2 (en) * 1982-11-24 1992-10-08 Tsumura & Co
EP0227108A2 (en) 1985-12-27 1987-07-01 Lion Corporation Oral composition
JPS62205016A (en) * 1986-03-05 1987-09-09 Sankin Kogyo Kk Denture cleaner
JPH04346933A (en) * 1991-05-24 1992-12-02 Pokka Corp Multiplication inhibitor against dental caries fungus and pathogenic fungus of periodontal disease
JPH09143084A (en) * 1995-11-27 1997-06-03 Heetee Seika Kk Preparation of anti-tooth caries agent and anti-tooth cariesfood using this
WO1998006377A1 (en) * 1996-08-12 1998-02-19 The Procter & Gamble Company Oral compositions
WO1998006414A1 (en) * 1996-08-12 1998-02-19 The Procter & Gamble Company Oral compositions comprising honeysuckle flowers and/or goldthread extracts
WO2000067707A1 (en) * 1999-05-06 2000-11-16 Yuzo Tsuchida Cleansers containing kumazasa extract
WO2001085116A3 (en) * 2000-05-10 2002-05-23 Colgate Palmolive Co Synergistic antiplaque/antigingivitis oral composition
US6500409B1 (en) * 2000-05-10 2002-12-31 Colgate Palmolive Company Synergistic antiplaque/antigingivitis oral composition
JP2002020253A (en) * 2000-07-05 2002-01-23 Kobayashi Pharmaceut Co Ltd Composition for oral use
KR100407651B1 (en) * 2000-12-11 2003-12-01 최동성 Novel use of functional Coptis chinensis Franch extract and process for preparation thereof
US6702999B2 (en) 2001-05-15 2004-03-09 The Procter & Gamble Co. Oral care compositions
US6703000B2 (en) 2001-05-15 2004-03-09 The Procter & Gamble Co. Confectionery compositions
US6706256B2 (en) 2001-05-15 2004-03-16 The Procter & Gamble Co. Oral care compositions
US6726897B2 (en) 2001-05-15 2004-04-27 The Procter & Gamble Co. Confectionery compositions
US6730291B2 (en) 2001-05-15 2004-05-04 The Procter & Gamble Co. Confectionery compositions
WO2003099110A3 (en) * 2002-05-28 2004-06-17 Univ California Herbs and herbal combinations useful for the treatment of microbial infections
US7595065B2 (en) 2002-06-25 2009-09-29 Wm. Wrigley Jr. Company Breath freshening and oral cleansing products with synergistic combinations of magnolia bark extract and essential oils
US8163304B2 (en) 2002-06-25 2012-04-24 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract in combination with surface active agents
US8012514B2 (en) 2002-06-25 2011-09-06 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with Magnolia Bark Extract
US7632525B2 (en) 2002-06-25 2009-12-15 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract in combination with surface active agents
US7347985B2 (en) * 2002-06-25 2008-03-25 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product with magnolia bark extract
KR100828656B1 (en) * 2003-07-29 2008-05-09 가부시키가이샤 호오도 Periodontal disease therapeutic and/or preventive composition
KR100884362B1 (en) * 2003-07-29 2009-02-18 가부시키가이샤 호오도 Periodontal disease therapeutic and/or preventive composition
WO2005009454A1 (en) * 2003-07-29 2005-02-03 Hououdou Co., Ltd. Periodontal disease therapeutic and/or preventive composition
US8343556B2 (en) 2003-07-29 2013-01-01 Hououdou Co., Ltd. Composition for treating and/or preventing periodontal disease
JP2005162697A (en) * 2003-12-04 2005-06-23 Lotte Co Ltd Methioninase inhibitor and oral cavity composition, food and drink containing the same
WO2007011504A1 (en) * 2005-07-14 2007-01-25 Wm. Wrigley Jr. Company Breath freshening and oral cleansing product comprising a magnolia bark extract and surfactant
WO2007126651A3 (en) * 2006-03-29 2008-03-13 Wrigley W M Jun Co Breath freshening and oral cleansing products with synergistic combinations of magnolia bark extract and essential oils
JP2013520518A (en) * 2010-02-24 2013-06-06 コルゲート・パーモリブ・カンパニー Oral care composition
JP2015212274A (en) * 2010-02-24 2015-11-26 コルゲート・パーモリブ・カンパニーColgate−Palmolive Company Oral care composition
JP2013532684A (en) * 2010-07-29 2013-08-19 コルゲート・パーモリブ・カンパニー Phosphate-free oral care composition based on magnolia-derived antibacterial agent
US9125860B2 (en) 2010-07-29 2015-09-08 Colgate-Palmolive Company Phosphate free oral care compositions based on magnolia antibacterial agent
JP2014505077A (en) * 2011-01-31 2014-02-27 コルゲート・パーモリブ・カンパニー Oral care composition
US10071159B2 (en) 2011-01-31 2018-09-11 Colgate-Palmolive Company Oral care compositions
JP2015030701A (en) * 2013-08-02 2015-02-16 有限会社漢方歯科医学研究所 Antibacterial composition for oral cavity
JP2018052969A (en) * 2017-11-29 2018-04-05 有限会社漢方歯科医学研究所 Antibacterial composition for oral cavity
CN115944572A (en) * 2023-02-07 2023-04-11 湖南天华医药生物科技有限公司 Toothpaste based on nutgall extract and preparation method thereof

Also Published As

Publication number Publication date
JPH0138084B2 (en) 1989-08-11

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