JPS5740412A - Manufacture of virus antigen - Google Patents

Manufacture of virus antigen

Info

Publication number
JPS5740412A
JPS5740412A JP56100747A JP10074781A JPS5740412A JP S5740412 A JPS5740412 A JP S5740412A JP 56100747 A JP56100747 A JP 56100747A JP 10074781 A JP10074781 A JP 10074781A JP S5740412 A JPS5740412 A JP S5740412A
Authority
JP
Japan
Prior art keywords
cells
respiratory syncytial
syncytial virus
produced
cell strain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56100747A
Other languages
English (en)
Other versions
JPH0380474B2 (ja
Inventor
Jieimuzu Sutotsuto Edowaado
Haatorando Tomasu Ruisu
Jiin Jiebetsuto Nooma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Development Corp UK
National Research Development Corp of India
Original Assignee
National Research Development Corp UK
National Research Development Corp of India
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Development Corp UK, National Research Development Corp of India filed Critical National Research Development Corp UK
Publication of JPS5740412A publication Critical patent/JPS5740412A/ja
Publication of JPH0380474B2 publication Critical patent/JPH0380474B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1027Paramyxoviridae, e.g. respiratory syncytial virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18561Methods of inactivation or attenuation
    • C12N2760/18564Methods of inactivation or attenuation by serial passage
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18611Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56100747A 1980-07-01 1981-06-30 Manufacture of virus antigen Granted JPS5740412A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8021434 1980-07-01

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2115712A Division JPH02291262A (ja) 1980-07-01 1990-05-01 呼吸器シンシチウム抗原

Publications (2)

Publication Number Publication Date
JPS5740412A true JPS5740412A (en) 1982-03-06
JPH0380474B2 JPH0380474B2 (ja) 1991-12-25

Family

ID=10514423

Family Applications (2)

Application Number Title Priority Date Filing Date
JP56100747A Granted JPS5740412A (en) 1980-07-01 1981-06-30 Manufacture of virus antigen
JP2115712A Granted JPH02291262A (ja) 1980-07-01 1990-05-01 呼吸器シンシチウム抗原

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2115712A Granted JPH02291262A (ja) 1980-07-01 1990-05-01 呼吸器シンシチウム抗原

Country Status (11)

Country Link
US (2) US4517304A (ja)
EP (1) EP0043272B1 (ja)
JP (2) JPS5740412A (ja)
AT (1) ATE7855T1 (ja)
AU (2) AU554080B2 (ja)
CA (1) CA1188985A (ja)
DE (1) DE3164143D1 (ja)
GB (1) GB2079786B (ja)
NL (1) NL300020I2 (ja)
NZ (1) NZ197553A (ja)
ZA (1) ZA814386B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1267087A (en) * 1985-02-14 1990-03-27 Nicolaas Visser Synthetic immunogen
US4814269A (en) * 1985-03-29 1989-03-21 Cenfold Holdings S.A. Diagnostic testing for antibodies against microorganisms
US5149650A (en) * 1986-01-14 1992-09-22 University Of North Carolina At Chapel Hill Vaccines for human respiratory virus
US6291228B1 (en) 1988-08-03 2001-09-18 Vericore Limited Vaccine
US5824307A (en) * 1991-12-23 1998-10-20 Medimmune, Inc. Human-murine chimeric antibodies against respiratory syncytial virus
DE4207317C3 (de) * 1992-03-06 2000-03-16 Heraeus Electro Nite Int Vorrichtung zur Messung der Temperatur von Metallschmelzen
ATE249838T1 (de) * 1993-05-12 2003-10-15 Chiron Corp Konserviertes motiv der hepatitis c virus e2/ns1 region
US5723130A (en) 1993-05-25 1998-03-03 Hancock; Gerald E. Adjuvants for vaccines against respiratory syncytial virus
US7223410B1 (en) 1994-08-05 2007-05-29 Sanofi Pasteur Limited Inactivated respiratory syncytial viral vaccines
DK0714306T3 (da) * 1993-08-06 1998-10-19 Connaught Lab Inaktiveret respiratorisk syncytialvirus-vacciner
US5811524A (en) * 1995-06-07 1998-09-22 Idec Pharmaceuticals Corporation Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
GB9924990D0 (en) * 1999-10-21 1999-12-22 Glaxo Group Ltd Medicaments
MXPA02004627A (es) * 1999-11-08 2004-02-18 Biomune Vacunas contra el micoplasma bovis y sus metodos de uso.
WO2001064751A2 (en) 2000-03-01 2001-09-07 Medimmune, Inc. High potency recombinant antibodies and method for producing them
DK1265928T3 (da) * 2000-01-27 2010-11-15 Medimmune Llc RSV-neutraliserende antistoffer med ultra høj affinitet
US7179900B2 (en) * 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US6855493B2 (en) 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7132100B2 (en) 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
JP2008518936A (ja) * 2004-10-29 2008-06-05 メディミューン,インコーポレーテッド Rsv感染症および関連状態を予防および治療する方法
EP1997830A1 (en) 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV specific binding molecules and means for producing them
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53121924A (en) * 1977-02-09 1978-10-24 Merck & Co Inc Respiratory syncytial vaccine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226743A (ja) * 1967-04-19 1971-03-31
US3919044A (en) * 1973-03-28 1975-11-11 Armour Pharma Processes for concentrating and purifying viruses and viral antigens
FR2227861B1 (ja) * 1973-05-04 1976-07-02 Anvar
US4112068A (en) * 1976-08-11 1978-09-05 Cutter Laboratories, Inc. Canine lung cell strain culture systems and processes for the cultivation of viruses and vaccines therefrom
US4122167A (en) * 1977-02-09 1978-10-24 Merck & Co., Inc. Respiratory synctial vaccine
LU79503A1 (fr) * 1977-08-17 1978-11-28 Merck & Co Inc Procede de preparation d'un vaccin syncytial du virus respiratoire

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53121924A (en) * 1977-02-09 1978-10-24 Merck & Co Inc Respiratory syncytial vaccine

Also Published As

Publication number Publication date
JPH0553474B2 (ja) 1993-08-10
US5071758A (en) 1991-12-10
NZ197553A (en) 1985-03-20
AU7241581A (en) 1982-01-07
NL300020I2 (nl) 2001-08-01
DE3164143D1 (en) 1984-07-19
AU554080B2 (en) 1986-08-07
EP0043272A1 (en) 1982-01-06
ATE7855T1 (de) 1984-06-15
AU5841286A (en) 1986-11-20
JPH0380474B2 (ja) 1991-12-25
EP0043272B1 (en) 1984-06-13
GB2079786B (en) 1984-11-14
NL300020I1 (nl) 2000-12-01
AU588885B2 (en) 1989-09-28
ZA814386B (en) 1982-07-28
JPH02291262A (ja) 1990-12-03
GB2079786A (en) 1982-01-27
US4517304A (en) 1985-05-14
CA1188985A (en) 1985-06-18

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