JPS57188570A - Benzylazole derivative - Google Patents
Benzylazole derivativeInfo
- Publication number
- JPS57188570A JPS57188570A JP56072986A JP7298681A JPS57188570A JP S57188570 A JPS57188570 A JP S57188570A JP 56072986 A JP56072986 A JP 56072986A JP 7298681 A JP7298681 A JP 7298681A JP S57188570 A JPS57188570 A JP S57188570A
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- compound expressed
- halogen
- benzylazole
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56072986A JPS57188570A (en) | 1981-05-14 | 1981-05-14 | Benzylazole derivative |
US06/372,951 US4430331A (en) | 1981-05-14 | 1982-04-29 | Antiarrhytmic benzylimidazole |
AU83180/82A AU554243B2 (en) | 1981-05-14 | 1982-04-30 | Benzylazole derivatives |
NZ200471A NZ200471A (en) | 1981-05-14 | 1982-04-30 | Benzylazole derivatives and pharmaceutical compositions |
ZA823207A ZA823207B (en) | 1981-05-14 | 1982-05-10 | Benzylazole derivatives |
CA000403693A CA1193255A (en) | 1981-05-14 | 1982-05-11 | Benzylazone derivatives |
IL65735A IL65735A (en) | 1981-05-14 | 1982-05-11 | Azolylalkyl(alkenyl)phenoxypropanolamine derivatives,process for their preparation and pharmaceutical or veterinary formulations comprising them |
IE1134/82A IE52989B1 (en) | 1981-05-14 | 1982-05-11 | Phenoxypropanolamine derivatives |
ES512151A ES8303400A1 (es) | 1981-05-14 | 1982-05-13 | "procedimiento para preparar derivados de bencilazol." |
DK216282A DK161317C (da) | 1981-05-14 | 1982-05-13 | Analogifremgangsmaade til fremstilling af 2-(1-(1-imidazolyl)vinyl)-phenoxypropanolderivater |
EP82104196A EP0066144B1 (en) | 1981-05-14 | 1982-05-13 | Benzylazole derivatives |
HU821509A HU188059B (en) | 1981-05-14 | 1982-05-13 | Process for producing benzylazole derivatives |
GB08213956A GB2103600B (en) | 1981-05-14 | 1982-05-13 | Phenoxypropanolamines |
PH27294A PH17989A (en) | 1981-05-14 | 1982-05-13 | Benzylazole derivatives |
DE198282104196T DE66144T1 (de) | 1981-05-14 | 1982-05-13 | Benzylazole-derivate. |
DE8282104196T DE3269141D1 (de) | 1981-05-14 | 1982-05-13 | Benzylazole derivatives |
KR8202102A KR860001580B1 (ko) | 1981-05-14 | 1982-05-14 | 벤질아졸 유도체의 제조 방법 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56072986A JPS57188570A (en) | 1981-05-14 | 1981-05-14 | Benzylazole derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57188570A true JPS57188570A (en) | 1982-11-19 |
JPS6325583B2 JPS6325583B2 (ja) | 1988-05-26 |
Family
ID=13505217
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56072986A Granted JPS57188570A (en) | 1981-05-14 | 1981-05-14 | Benzylazole derivative |
Country Status (16)
Country | Link |
---|---|
US (1) | US4430331A (ja) |
EP (1) | EP0066144B1 (ja) |
JP (1) | JPS57188570A (ja) |
KR (1) | KR860001580B1 (ja) |
AU (1) | AU554243B2 (ja) |
CA (1) | CA1193255A (ja) |
DE (2) | DE3269141D1 (ja) |
DK (1) | DK161317C (ja) |
ES (1) | ES8303400A1 (ja) |
GB (1) | GB2103600B (ja) |
HU (1) | HU188059B (ja) |
IE (1) | IE52989B1 (ja) |
IL (1) | IL65735A (ja) |
NZ (1) | NZ200471A (ja) |
PH (1) | PH17989A (ja) |
ZA (1) | ZA823207B (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3343671A1 (de) * | 1983-12-02 | 1985-06-20 | Basf Ag, 6700 Ludwigshafen | Aminopropanolderivate von substituierten 2-hydroxy-propiophenonen, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3870726A (en) | 1970-09-09 | 1975-03-11 | Bayer Ag | Derivatives of 3-azolylpropyne and processes for their preparation and use |
CH584695A5 (en) * | 1973-02-20 | 1977-02-15 | Ciba Geigy Ag | 3-amino-2-hydroxypropoxy substd. diazines and pyridines - with beta-adrenergic blocking or stimulating activity |
SE7601713L (sv) * | 1975-03-03 | 1976-09-06 | Merck & Co Inc | Nya, substituerad imidazoler |
JPS5488268A (en) * | 1977-10-19 | 1979-07-13 | Wellcome Found | Novel imidazole derivatives*their manufacture and medical composition |
US4210653A (en) * | 1978-06-27 | 1980-07-01 | Merck & Co., Inc. | Pyridyloxypropanolamines |
JPS5951943B2 (ja) * | 1978-08-21 | 1984-12-17 | キツセイ薬品工業株式会社 | 新規なイミダゾ−ル誘導体 |
GB2041363B (en) * | 1979-01-19 | 1982-10-06 | Pfizer Ltd | N-benzyl-imidazoles |
DK157860C (da) * | 1979-06-07 | 1990-07-30 | Shionogi & Co | Analogifremgangsmaade til fremstilling af benzylimidazolderivater samt farmaceutisk acceptable syreadditionssalte deraf |
EP0034116A3 (en) * | 1980-02-11 | 1981-09-02 | Berlex Laboratories, Inc. | N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines |
CA1156661A (en) * | 1980-02-25 | 1983-11-08 | Hoffmann-La Roche Limited | Phenoxy-aminopropanol derivatives |
-
1981
- 1981-05-14 JP JP56072986A patent/JPS57188570A/ja active Granted
-
1982
- 1982-04-29 US US06/372,951 patent/US4430331A/en not_active Expired - Fee Related
- 1982-04-30 AU AU83180/82A patent/AU554243B2/en not_active Ceased
- 1982-04-30 NZ NZ200471A patent/NZ200471A/en unknown
- 1982-05-10 ZA ZA823207A patent/ZA823207B/xx unknown
- 1982-05-11 IL IL65735A patent/IL65735A/xx not_active IP Right Cessation
- 1982-05-11 IE IE1134/82A patent/IE52989B1/en not_active IP Right Cessation
- 1982-05-11 CA CA000403693A patent/CA1193255A/en not_active Expired
- 1982-05-13 ES ES512151A patent/ES8303400A1/es not_active Expired
- 1982-05-13 DE DE8282104196T patent/DE3269141D1/de not_active Expired
- 1982-05-13 PH PH27294A patent/PH17989A/en unknown
- 1982-05-13 DK DK216282A patent/DK161317C/da not_active IP Right Cessation
- 1982-05-13 HU HU821509A patent/HU188059B/hu not_active IP Right Cessation
- 1982-05-13 EP EP82104196A patent/EP0066144B1/en not_active Expired
- 1982-05-13 DE DE198282104196T patent/DE66144T1/de active Pending
- 1982-05-13 GB GB08213956A patent/GB2103600B/en not_active Expired
- 1982-05-14 KR KR8202102A patent/KR860001580B1/ko active
Also Published As
Publication number | Publication date |
---|---|
ES512151A0 (es) | 1983-02-01 |
CA1193255A (en) | 1985-09-10 |
JPS6325583B2 (ja) | 1988-05-26 |
GB2103600A (en) | 1983-02-23 |
ZA823207B (en) | 1983-03-30 |
AU554243B2 (en) | 1986-08-14 |
PH17989A (en) | 1985-02-28 |
IL65735A (en) | 1986-04-29 |
EP0066144A2 (en) | 1982-12-08 |
EP0066144B1 (en) | 1986-02-19 |
DE3269141D1 (de) | 1986-03-27 |
IE52989B1 (en) | 1988-04-27 |
DK161317C (da) | 1991-12-30 |
US4430331A (en) | 1984-02-07 |
EP0066144A3 (en) | 1983-11-30 |
HU188059B (en) | 1986-03-28 |
DE66144T1 (de) | 1983-05-26 |
ES8303400A1 (es) | 1983-02-01 |
DK161317B (da) | 1991-06-24 |
DK216282A (da) | 1982-11-15 |
IL65735A0 (en) | 1982-08-31 |
NZ200471A (en) | 1985-08-30 |
AU8318082A (en) | 1982-11-18 |
KR860001580B1 (ko) | 1986-10-10 |
KR830010079A (ko) | 1983-12-26 |
GB2103600B (en) | 1985-01-09 |
IE821134L (en) | 1982-11-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU5154485A (en) | Tetrahydrobenzthiazoles | |
DE3370621D1 (en) | 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines, a process for preparing the same and their use as medicaments | |
ES300059A1 (es) | Procedimiento de preparación de aminas y sus derivados de adición | |
PL243409A1 (en) | Process for preparing novel derivatives of 1,2,4-triazole | |
DE3160360D1 (en) | 5-subsituted 5,10-dihydro-11h-dibenzo(b,e)(1,4)diazepin-11-ones, process for preparing them and medicaments containing them | |
NZ216750A (en) | Morpholino derivatives and fungicides | |
JPS57188570A (en) | Benzylazole derivative | |
ZA838065B (en) | Derivatives of piperidenedione,process for preparing them and drugs containing said derivatives | |
ES8502988A1 (es) | Procedimiento para preparar derivados de piperacina. | |
JPS57181069A (en) | Delta2-1,2,4-triazolin-5-one and its preparation and use | |
JPS55129255A (en) | Farnesylacetamide compounds or their salts | |
GB1122756A (en) | Amino-substituted naphthalene derivatives | |
JPS51125291A (en) | A process for preparing novel carbostyryl derivatives | |
ES8505994A1 (es) | Un metodo para preparar 2(1h)-piridinonas | |
JPS57183761A (en) | Carbostyril derivative | |
ES8302679A1 (es) | Procedimiento de preparacion de una 1-(trialcoxibencil)pi- perazina. | |
JPS57175174A (en) | Trithiotriazine compound and vulcanization of rubber using the same | |
JPS5285143A (en) | Antimicrobial agents and method of preparing same | |
ES319942A1 (es) | Procedimiento para la obtencion de 3 ',4',5'-trimetoxi-3-aminoacrilofenona. | |
JPS5661373A (en) | Piperazine derivative | |
JPS52153963A (en) | Novel 3-substituted pyrrolidine derivatives and method of preparing same | |
HUT54355A (en) | Process for producing imidazole derivatives of substituted benzoylurea, as well as antitumoural compositions comprising such compounds | |
JPS5659760A (en) | 3-aminopyrazole derivative | |
GB740307A (en) | New amide-like derivatives of piperidine and process for their preparation | |
JPS5714585A (en) | 1-cycloalkylmethylpiperazine derivative |