JPS57169422A - Novel antiulcer substance horphyosine and its preparation - Google Patents

Novel antiulcer substance horphyosine and its preparation

Info

Publication number
JPS57169422A
JPS57169422A JP56056178A JP5617881A JPS57169422A JP S57169422 A JPS57169422 A JP S57169422A JP 56056178 A JP56056178 A JP 56056178A JP 5617881 A JP5617881 A JP 5617881A JP S57169422 A JPS57169422 A JP S57169422A
Authority
JP
Japan
Prior art keywords
sargassum
horphyosine
kjellman
yamada
chloroform
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56056178A
Other languages
Japanese (ja)
Other versions
JPS6045854B2 (en
Inventor
Yoshio Sakagami
Toshio Kamibayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP56056178A priority Critical patent/JPS6045854B2/en
Publication of JPS57169422A publication Critical patent/JPS57169422A/en
Publication of JPS6045854B2 publication Critical patent/JPS6045854B2/en
Expired legal-status Critical Current

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  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

NEW MATERIAL:Horphyosine having the following physical and chemical properties: appearance, neutral colorless flaky crystal; melting point, 124W125°C; specific rotation,[α]D27=-40.4 (C=1.0, chloroform); molecular formula C27H42O3; molecular weight, 414 (mass spectrometry); solublitity, hardly soluble in water, soluble in methanol, ethanol, etc.; color reaction, changes to brown color with concentrated sulfuric acid, negative to ninhydrin reaction, etc.; etc.
USE: Antiulcer agent.
PROCESS: Seaweeds such as Porphyra tenera Kjellman, Ulva pertusa Kjellman, Ecklonia cava Kjellman, Ulva fasciata Delile, Eisenia bicyclis Setchell, Sargassum ringgoldianum Harvey, Grateloupia turuturu Yamada, Gracilaria textorii Suringar, Sargassum tenuifolium Yamada, Sargassum tortile C.Agardh, Sargassum thunbergii O.Kuntze, Ishige foliacea Okamura, Ishige Okamurai Yendo, etc. are washed with water, and without or after drying, extracted with an organic solvent (e.g. n-hexane, benzene, chloroform, etc.). The extract is concentrated and purified by adsorption chromatography, etc. to obtain pure crystalline horphyosine. Dose: 2W3g/day for oral administration and ≤1,000mg/day for injection.
COPYRIGHT: (C)1982,JPO&Japio
JP56056178A 1981-04-13 1981-04-13 New anti-ulcer substance phorhuiosin and its production method Expired JPS6045854B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56056178A JPS6045854B2 (en) 1981-04-13 1981-04-13 New anti-ulcer substance phorhuiosin and its production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56056178A JPS6045854B2 (en) 1981-04-13 1981-04-13 New anti-ulcer substance phorhuiosin and its production method

Publications (2)

Publication Number Publication Date
JPS57169422A true JPS57169422A (en) 1982-10-19
JPS6045854B2 JPS6045854B2 (en) 1985-10-12

Family

ID=13019849

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56056178A Expired JPS6045854B2 (en) 1981-04-13 1981-04-13 New anti-ulcer substance phorhuiosin and its production method

Country Status (1)

Country Link
JP (1) JPS6045854B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7691388B2 (en) * 2006-03-24 2010-04-06 Ocean Nutrition Canada Limited Compositions comprising Porphyra and methods of making and using thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54156690A (en) * 1978-05-31 1979-12-10 Matsushita Electric Ind Co Ltd Humidity sensing element

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54156690A (en) * 1978-05-31 1979-12-10 Matsushita Electric Ind Co Ltd Humidity sensing element

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7691388B2 (en) * 2006-03-24 2010-04-06 Ocean Nutrition Canada Limited Compositions comprising Porphyra and methods of making and using thereof

Also Published As

Publication number Publication date
JPS6045854B2 (en) 1985-10-12

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