JPS57134497A - 2,3-di-o-acyl-d-ribofuranose 1,5-diphosphate, its preparation and use - Google Patents

2,3-di-o-acyl-d-ribofuranose 1,5-diphosphate, its preparation and use

Info

Publication number
JPS57134497A
JPS57134497A JP56018956A JP1895681A JPS57134497A JP S57134497 A JPS57134497 A JP S57134497A JP 56018956 A JP56018956 A JP 56018956A JP 1895681 A JP1895681 A JP 1895681A JP S57134497 A JPS57134497 A JP S57134497A
Authority
JP
Japan
Prior art keywords
ribofuranose
diphosphate
acyl
compound shown
formulai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56018956A
Other languages
Japanese (ja)
Other versions
JPS648639B2 (en
Inventor
Toshihiko Azuma
Hiroshi Honda
Yoshinori Kobayashi
Takashi Yamashita
Takeo Komori
Hisaaki Uchida
Hideo Nagae
Kimio Hirose
Shinjiro Iwasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MEITOU SANGYO KK
Meito Sangyo KK
Original Assignee
MEITOU SANGYO KK
Meito Sangyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEITOU SANGYO KK, Meito Sangyo KK filed Critical MEITOU SANGYO KK
Priority to JP56018956A priority Critical patent/JPS57134497A/en
Publication of JPS57134497A publication Critical patent/JPS57134497A/en
Publication of JPS648639B2 publication Critical patent/JPS648639B2/ja
Granted legal-status Critical Current

Links

Classifications

    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI(R2 is ≤7C acyl group).
EXAMPLE: 2,3-Di-O-propionyl-D-ribofuranose 1,5-diphosphate.
USE: A hypoglycemic. A promotor for feeding oxygen to peripheral tissue.
PROCESS: For example, a 2,3-di-O-acyl-D-ribofuranose 1,5-diphosphate derivative shown by the formula II (R1 is a protecting group removal under catalystic hydrogen reduction, such as lower alkyl, substituted phenyl, benzyl, etc.) is subjected to catalystic hydrogen reduction in the presence of a solvent such as ethyl acetate, etc. using a novel catalyst such as platinum, palladium, etc. at about -10W+50°C, to give a compound shown by the formulaI. The amount of the catalyst of novel metal used is preferably about 1W50wt% based on the compound shown by the formula II.
COPYRIGHT: (C)1982,JPO&Japio
JP56018956A 1981-02-13 1981-02-13 2,3-di-o-acyl-d-ribofuranose 1,5-diphosphate, its preparation and use Granted JPS57134497A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56018956A JPS57134497A (en) 1981-02-13 1981-02-13 2,3-di-o-acyl-d-ribofuranose 1,5-diphosphate, its preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56018956A JPS57134497A (en) 1981-02-13 1981-02-13 2,3-di-o-acyl-d-ribofuranose 1,5-diphosphate, its preparation and use

Publications (2)

Publication Number Publication Date
JPS57134497A true JPS57134497A (en) 1982-08-19
JPS648639B2 JPS648639B2 (en) 1989-02-14

Family

ID=11986093

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56018956A Granted JPS57134497A (en) 1981-02-13 1981-02-13 2,3-di-o-acyl-d-ribofuranose 1,5-diphosphate, its preparation and use

Country Status (1)

Country Link
JP (1) JPS57134497A (en)

Also Published As

Publication number Publication date
JPS648639B2 (en) 1989-02-14

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