JPS5690044A - 2- secondary aminoacetyl aniline - Google Patents

2- secondary aminoacetyl aniline

Info

Publication number
JPS5690044A
JPS5690044A JP16720679A JP16720679A JPS5690044A JP S5690044 A JPS5690044 A JP S5690044A JP 16720679 A JP16720679 A JP 16720679A JP 16720679 A JP16720679 A JP 16720679A JP S5690044 A JPS5690044 A JP S5690044A
Authority
JP
Japan
Prior art keywords
formula
compound
secondary amine
aniline
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP16720679A
Other languages
Japanese (ja)
Inventor
Tsutomu Sugasawa
Kazuyuki Sasakura
Makoto Adachi
Motohiko Ueda
Sadatoshi Kimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP16720679A priority Critical patent/JPS5690044A/en
Publication of JPS5690044A publication Critical patent/JPS5690044A/en
Pending legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A compound of formula I (R is secondary amino; X is halogen, alkyl or alkoxyl) and a pharmaceutically acceptable acid addition salt thereof.
EXAMPLE: 4-Chloro-2-(4-methyl-1-piperazinylacetyl)aniline.
USE: An antiarrhythmic agent.
PROCESS: A compound of formula II (Y is halogen) is reacted with a desired secondary amine of formula IV to give a secondary amine derivative which is the titled compound of formula I. The reaction is carried out by reacting the compound of formula II with the desired secondary amine in a suitable inert solvent, e.g. methylene chloride or dimethyl sulfoxide, at 0W100°C, preferably about room temperature.
COPYRIGHT: (C)1981,JPO&Japio
JP16720679A 1979-12-21 1979-12-21 2- secondary aminoacetyl aniline Pending JPS5690044A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16720679A JPS5690044A (en) 1979-12-21 1979-12-21 2- secondary aminoacetyl aniline

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16720679A JPS5690044A (en) 1979-12-21 1979-12-21 2- secondary aminoacetyl aniline

Publications (1)

Publication Number Publication Date
JPS5690044A true JPS5690044A (en) 1981-07-21

Family

ID=15845383

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16720679A Pending JPS5690044A (en) 1979-12-21 1979-12-21 2- secondary aminoacetyl aniline

Country Status (1)

Country Link
JP (1) JPS5690044A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816489A (en) * 1984-08-20 1989-03-28 Laboratoire L. Lafon 1-(aminophenyl)-2-aminoethanone derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816489A (en) * 1984-08-20 1989-03-28 Laboratoire L. Lafon 1-(aminophenyl)-2-aminoethanone derivatives

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