JPS5690044A - 2- secondary aminoacetyl aniline - Google Patents
2- secondary aminoacetyl anilineInfo
- Publication number
- JPS5690044A JPS5690044A JP16720679A JP16720679A JPS5690044A JP S5690044 A JPS5690044 A JP S5690044A JP 16720679 A JP16720679 A JP 16720679A JP 16720679 A JP16720679 A JP 16720679A JP S5690044 A JPS5690044 A JP S5690044A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- secondary amine
- aniline
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A compound of formula I (R is secondary amino; X is halogen, alkyl or alkoxyl) and a pharmaceutically acceptable acid addition salt thereof.
EXAMPLE: 4-Chloro-2-(4-methyl-1-piperazinylacetyl)aniline.
USE: An antiarrhythmic agent.
PROCESS: A compound of formula II (Y is halogen) is reacted with a desired secondary amine of formula IV to give a secondary amine derivative which is the titled compound of formula I. The reaction is carried out by reacting the compound of formula II with the desired secondary amine in a suitable inert solvent, e.g. methylene chloride or dimethyl sulfoxide, at 0W100°C, preferably about room temperature.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16720679A JPS5690044A (en) | 1979-12-21 | 1979-12-21 | 2- secondary aminoacetyl aniline |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16720679A JPS5690044A (en) | 1979-12-21 | 1979-12-21 | 2- secondary aminoacetyl aniline |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5690044A true JPS5690044A (en) | 1981-07-21 |
Family
ID=15845383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16720679A Pending JPS5690044A (en) | 1979-12-21 | 1979-12-21 | 2- secondary aminoacetyl aniline |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5690044A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816489A (en) * | 1984-08-20 | 1989-03-28 | Laboratoire L. Lafon | 1-(aminophenyl)-2-aminoethanone derivatives |
-
1979
- 1979-12-21 JP JP16720679A patent/JPS5690044A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816489A (en) * | 1984-08-20 | 1989-03-28 | Laboratoire L. Lafon | 1-(aminophenyl)-2-aminoethanone derivatives |
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