JPS5658493A - Preparation of n-carbamoyl-d-alpha-amino acids - Google Patents
Preparation of n-carbamoyl-d-alpha-amino acidsInfo
- Publication number
- JPS5658493A JPS5658493A JP13408279A JP13408279A JPS5658493A JP S5658493 A JPS5658493 A JP S5658493A JP 13408279 A JP13408279 A JP 13408279A JP 13408279 A JP13408279 A JP 13408279A JP S5658493 A JPS5658493 A JP S5658493A
- Authority
- JP
- Japan
- Prior art keywords
- carbamoyl
- cells
- alpha
- preparation
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To prepare an N-carbamoyl-D-α-amino acid from a 5-substituted hydantoin, by the use of hydantoinase derived from microorganisms belonging to Bacillus genus.
CONSTITUTION: Microorganism belonging to Bacillus genus and capable of asymmetrically opening and hydrolyzing hydantoin ring, e.g. Bacillus sp. AKU-0242 (FERM-P No.5214) is cultured in an alkaline medium having a pH value of 8.5W 12.0. The cultured bacterial cells, treated cells, or the enzyme extracted from said cells, are reacted with the DL- or L-isomer of a 5-substituted hydantoin of formula I (R is alkyl, aralkyl, heterocyclic group, aromatic hydrocarbon group, etc.) to obtain the N-carbamoyl-D-α-amino acid of formula II (R is the same as defined above).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13408279A JPS5658493A (en) | 1979-10-16 | 1979-10-16 | Preparation of n-carbamoyl-d-alpha-amino acids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13408279A JPS5658493A (en) | 1979-10-16 | 1979-10-16 | Preparation of n-carbamoyl-d-alpha-amino acids |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5658493A true JPS5658493A (en) | 1981-05-21 |
Family
ID=15119972
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13408279A Pending JPS5658493A (en) | 1979-10-16 | 1979-10-16 | Preparation of n-carbamoyl-d-alpha-amino acids |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5658493A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003106689A1 (en) * | 2002-06-05 | 2003-12-24 | 鐘淵化学工業株式会社 | PROCESS FOR PRODUCING OPTICALLY ACTIVE α-METHYLCYSTEINE DERIVATIVE |
-
1979
- 1979-10-16 JP JP13408279A patent/JPS5658493A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003106689A1 (en) * | 2002-06-05 | 2003-12-24 | 鐘淵化学工業株式会社 | PROCESS FOR PRODUCING OPTICALLY ACTIVE α-METHYLCYSTEINE DERIVATIVE |
US8993800B2 (en) | 2002-06-05 | 2015-03-31 | Kaneka Corporation | Process for producing optically active α-methylcysteine derivative |
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