JPS562990A - Purification of cepthalosporin - Google Patents
Purification of cepthalosporinInfo
- Publication number
- JPS562990A JPS562990A JP7930979A JP7930979A JPS562990A JP S562990 A JPS562990 A JP S562990A JP 7930979 A JP7930979 A JP 7930979A JP 7930979 A JP7930979 A JP 7930979A JP S562990 A JPS562990 A JP S562990A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- solvent
- cephalosporin
- solvated
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
PURPOSE: To prepare a specific cephalosporin compound in extremely high purity, useful as an antibacterial agent, by converting the crude product of the cephalosporin to a solvated compound with a crystalline amide solvent, and eliminating the solvent with water.
CONSTITUTION: A crude cephalosporin compound of formula (A is pyridine ring; R is OH-substituted phenyl; Het is tetrazole substituted with 1W4C alkyl group) is mixed with a mixture of an amide solvent and a ketone solvent to precipitate the solvated compound of the cephalosporin compound and the amide solvent. The crystals of the solvated compound is suspended or dissolved in a mixture of water and an organic solvent, and crystallized to obtain a highly pure compound of the formula.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7930979A JPS562990A (en) | 1979-06-22 | 1979-06-22 | Purification of cepthalosporin |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7930979A JPS562990A (en) | 1979-06-22 | 1979-06-22 | Purification of cepthalosporin |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS562990A true JPS562990A (en) | 1981-01-13 |
Family
ID=13686245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7930979A Pending JPS562990A (en) | 1979-06-22 | 1979-06-22 | Purification of cepthalosporin |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS562990A (en) |
-
1979
- 1979-06-22 JP JP7930979A patent/JPS562990A/en active Pending
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