JPS562990A - Purification of cepthalosporin - Google Patents

Purification of cepthalosporin

Info

Publication number
JPS562990A
JPS562990A JP7930979A JP7930979A JPS562990A JP S562990 A JPS562990 A JP S562990A JP 7930979 A JP7930979 A JP 7930979A JP 7930979 A JP7930979 A JP 7930979A JP S562990 A JPS562990 A JP S562990A
Authority
JP
Japan
Prior art keywords
compound
solvent
cephalosporin
solvated
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7930979A
Other languages
Japanese (ja)
Inventor
Hirotada Yamada
Hiroyuki Suzuki
Seiichi Jinbo
Hisao Tohiki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP7930979A priority Critical patent/JPS562990A/en
Publication of JPS562990A publication Critical patent/JPS562990A/en
Pending legal-status Critical Current

Links

Landscapes

  • Cephalosporin Compounds (AREA)

Abstract

PURPOSE: To prepare a specific cephalosporin compound in extremely high purity, useful as an antibacterial agent, by converting the crude product of the cephalosporin to a solvated compound with a crystalline amide solvent, and eliminating the solvent with water.
CONSTITUTION: A crude cephalosporin compound of formula (A is pyridine ring; R is OH-substituted phenyl; Het is tetrazole substituted with 1W4C alkyl group) is mixed with a mixture of an amide solvent and a ketone solvent to precipitate the solvated compound of the cephalosporin compound and the amide solvent. The crystals of the solvated compound is suspended or dissolved in a mixture of water and an organic solvent, and crystallized to obtain a highly pure compound of the formula.
COPYRIGHT: (C)1981,JPO&Japio
JP7930979A 1979-06-22 1979-06-22 Purification of cepthalosporin Pending JPS562990A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7930979A JPS562990A (en) 1979-06-22 1979-06-22 Purification of cepthalosporin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7930979A JPS562990A (en) 1979-06-22 1979-06-22 Purification of cepthalosporin

Publications (1)

Publication Number Publication Date
JPS562990A true JPS562990A (en) 1981-01-13

Family

ID=13686245

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7930979A Pending JPS562990A (en) 1979-06-22 1979-06-22 Purification of cepthalosporin

Country Status (1)

Country Link
JP (1) JPS562990A (en)

Similar Documents

Publication Publication Date Title
US4504658A (en) Epimerization of malonic acid esters
SE7907811L (en) AZETIDINYL COMPOUND FOR THE PREPARATION OF CEFEM COMPOUNDS AND PROCEDURE FOR ITS PREPARATION
IE41528L (en) Furfuryl-benzomorphane derivatives.
ATE148122T1 (en) OPTICALLY ACTIVE THIENOTRIAZOLODIAZEPINE COMPOUNDS
JPS562990A (en) Purification of cepthalosporin
JPS55144422A (en) Purification of cis-dichlorodiammineplatinum(2)
JPS5679628A (en) Preparation of isoprene
JPS5714590A (en) 2-benzyl-5-alkyl-tetrahydro-benzo(b)-1,6-naphthyridin-10-one derivative and its preparation
JPS54119493A (en) Purification of cephalosporins
JPS57144253A (en) Preparation of crude aminoalkylthiol
JPS54119497A (en) N-acylamino-alpha-arylacetamidocephalosporin derivative
JPS5533416A (en) Production of hexamethyene bis-dicyandiamide
JPS565483A (en) Purification of cephalosporin compound
JPS54119492A (en) Purification of cephalosporins
JPS57179189A (en) Production of rifampicin
JPS57192376A (en) Purification of 2-mercaptothiazolines
ES441965A1 (en) Acyl derivatives of clavulanic acid methods for their preparation and compositions containing them
JPS5528951A (en) Crystallization of antibiotic substance
JPS5616478A (en) Purification of benztriazole
JPS5466625A (en) Purification of 2-bromo-3-methylbutyrylurea
JPS549257A (en) Preparation of highly pure 1,8-dihydroanthraquinone
JPS56150046A (en) Production of 4-dimethylaminostilbene
JPS55139388A (en) Cephalosporin derivative
JPS5492991A (en) N-acyl cephalosporin derivative and its salt
JPS5653688A (en) Novel cephalosporin derivative and its preparation