JPS5625113A - Preparation of hemostatic collagen powder - Google Patents

Preparation of hemostatic collagen powder

Info

Publication number
JPS5625113A
JPS5625113A JP10040579A JP10040579A JPS5625113A JP S5625113 A JPS5625113 A JP S5625113A JP 10040579 A JP10040579 A JP 10040579A JP 10040579 A JP10040579 A JP 10040579A JP S5625113 A JPS5625113 A JP S5625113A
Authority
JP
Japan
Prior art keywords
collagen
pretreated
chips
purification
solubilizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10040579A
Other languages
Japanese (ja)
Other versions
JPS6236496B2 (en
Inventor
Tadaaki Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Priority to JP10040579A priority Critical patent/JPS5625113A/en
Publication of JPS5625113A publication Critical patent/JPS5625113A/en
Publication of JPS6236496B2 publication Critical patent/JPS6236496B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PURPOSE: To solubilize collagen chips without further pulverization, to facilitate the washing and purification, and to improve the purity and yield of collagen, by treating pretreated collagen chips with a protease capable of solubilizing collagen under specific weakly alkaline conditions.
CONSTITUTION: A collagen raw material obtained by removing impurities from crude collagen followed by purification and pelletizing, is pretreated with an aqueous mixture of caustic soda and sodium sulfate. The pretreated collagen is made to react with a protease capable of solubilizing collagen under weakly alkaline conditions of pH7W10 (e.g. "Pronase" , Trade name of Kaken Kagaku KK) for 10W30hr to effect the selective scission of the telo-peptide part without breaking the peptide linkage of the collagen molecule. The solubilized collagen thus obtained is washed with water and with a dilute acid solution, dried, and pulverized to 28W 400mesh powder.
COPYRIGHT: (C)1981,JPO&Japio
JP10040579A 1979-08-07 1979-08-07 Preparation of hemostatic collagen powder Granted JPS5625113A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10040579A JPS5625113A (en) 1979-08-07 1979-08-07 Preparation of hemostatic collagen powder

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10040579A JPS5625113A (en) 1979-08-07 1979-08-07 Preparation of hemostatic collagen powder

Publications (2)

Publication Number Publication Date
JPS5625113A true JPS5625113A (en) 1981-03-10
JPS6236496B2 JPS6236496B2 (en) 1987-08-07

Family

ID=14273064

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10040579A Granted JPS5625113A (en) 1979-08-07 1979-08-07 Preparation of hemostatic collagen powder

Country Status (1)

Country Link
JP (1) JPS5625113A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58103322A (en) * 1981-11-30 1983-06-20 ソシエテ・アノニム・ド・デヴロップマン・デ・ユテイリザ−ション・デュ・キュイ−ル Manufacture of collagen composition
EP0372966A2 (en) * 1988-12-08 1990-06-13 JOHNSON & JOHNSON MEDICAL, INC. Hemostatic collagen paste composition
JP2010233552A (en) * 2009-03-31 2010-10-21 Hamamatsu Univ School Of Medicine Highly sensitive detection method for highly virulent oral cavity bacteria

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51130519A (en) * 1975-05-01 1976-11-12 Nippi:Kk Process for preparating collagen powder for hemostasis
JPS5365358A (en) * 1976-11-22 1978-06-10 Nippi Inc Collagen fiber dispersion

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51130519A (en) * 1975-05-01 1976-11-12 Nippi:Kk Process for preparating collagen powder for hemostasis
JPS5365358A (en) * 1976-11-22 1978-06-10 Nippi Inc Collagen fiber dispersion

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58103322A (en) * 1981-11-30 1983-06-20 ソシエテ・アノニム・ド・デヴロップマン・デ・ユテイリザ−ション・デュ・キュイ−ル Manufacture of collagen composition
EP0372966A2 (en) * 1988-12-08 1990-06-13 JOHNSON & JOHNSON MEDICAL, INC. Hemostatic collagen paste composition
JP2010233552A (en) * 2009-03-31 2010-10-21 Hamamatsu Univ School Of Medicine Highly sensitive detection method for highly virulent oral cavity bacteria

Also Published As

Publication number Publication date
JPS6236496B2 (en) 1987-08-07

Similar Documents

Publication Publication Date Title
ES414186A1 (en) Crystallization seed-containing detergent composition
JPS5625113A (en) Preparation of hemostatic collagen powder
FR2357646A1 (en) TWO-STAGE METHOD OF ATTACKING HEMICELLULOSES OF NATURAL PRODUCTS CONTAINING XYLANE WITH A VIEW TO OBTAINING XYLOSE
GB906327A (en) Method of extracting polysaccharides
Wolfrom et al. The Structures of β-Diacetone-D-fructose and β-Monoacetone-D-fructose
JPS5623896A (en) Preparation of porous material of collagen
Wolfrom et al. Ethyl Glycosides of 2-Acetamido-2-deoxy-1-thio-D-galactose
KR960005426B1 (en) Method of preparation of carboxymethylcellulose with steam-explosion wood
US2929840A (en) Isolation of cystine
US2759868A (en) Manufacture of polymyxins b and e
RU2051876C1 (en) Method of preparation of air-entraining agent
JPS5829961B2 (en) Method for producing carboxymethylated products
JPS61212547A (en) Dehydroabiethylamino acid, salt thereof, and production thereof
JPS57118769A (en) Preparation of ground fish meat
US2573265A (en) Isolation of sterols
JPS52138505A (en) Preparation of granurated metallic soap
US2085768A (en) Method of separating and isolating the thyreotropic and the gonadotropic hormone of the anterior lobe of the hypophysis
JPS54141710A (en) Preparation of glycidyl ether
US2184775A (en) Method of producing hormone preparations of high purity
SU386660A1 (en)
SU81708A1 (en) Semicarbazone transdehydro-androsterone acetate method
RU2120407C1 (en) Method of production of potassium chloride from the spent electrolyte of magnesium production
SU663400A1 (en) Method of obtaining kolchamine
JPS5653649A (en) Separation of l-cystine
JPS5342204A (en) Production of granulated detergent