JPS56166117A - Antiinflammatory and analgesic adenosine derivative and therapeutical composition containing it as effective component - Google Patents

Antiinflammatory and analgesic adenosine derivative and therapeutical composition containing it as effective component

Info

Publication number
JPS56166117A
JPS56166117A JP5930181A JP5930181A JPS56166117A JP S56166117 A JPS56166117 A JP S56166117A JP 5930181 A JP5930181 A JP 5930181A JP 5930181 A JP5930181 A JP 5930181A JP S56166117 A JPS56166117 A JP S56166117A
Authority
JP
Japan
Prior art keywords
antiinflammatory
analgesic
composition containing
effective component
adenosine derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5930181A
Other languages
Japanese (ja)
Other versions
JPH0249288B2 (en
Inventor
Sutoramenchinori Jiyorujio
Gennari Fuederiko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
Bioresearch SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch SRL filed Critical Bioresearch SRL
Publication of JPS56166117A publication Critical patent/JPS56166117A/en
Publication of JPH0249288B2 publication Critical patent/JPH0249288B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP5930181A 1980-04-22 1981-04-21 Antiinflammatory and analgesic adenosine derivative and therapeutical composition containing it as effective component Granted JPS56166117A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (en) 1980-04-22 1980-04-22 ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP1022771A Division JPH01301692A (en) 1980-04-22 1989-02-02 Novel production of 5'-deoxy-5'- methylthioadenosine

Publications (2)

Publication Number Publication Date
JPS56166117A true JPS56166117A (en) 1981-12-21
JPH0249288B2 JPH0249288B2 (en) 1990-10-29

Family

ID=11183457

Family Applications (2)

Application Number Title Priority Date Filing Date
JP5930181A Granted JPS56166117A (en) 1980-04-22 1981-04-21 Antiinflammatory and analgesic adenosine derivative and therapeutical composition containing it as effective component
JP1022771A Granted JPH01301692A (en) 1980-04-22 1989-02-02 Novel production of 5'-deoxy-5'- methylthioadenosine

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP1022771A Granted JPH01301692A (en) 1980-04-22 1989-02-02 Novel production of 5'-deoxy-5'- methylthioadenosine

Country Status (17)

Country Link
JP (2) JPS56166117A (en)
AR (1) AR231144A1 (en)
BE (1) BE888472A (en)
CA (1) CA1198105A (en)
CH (2) CH645544A5 (en)
DE (1) DE3116067A1 (en)
DK (1) DK159453C (en)
ES (2) ES501539A0 (en)
FI (1) FI70227C (en)
FR (1) FR2491761A1 (en)
GB (3) GB2074446B (en)
IT (1) IT1193529B (en)
LU (1) LU83307A1 (en)
MX (1) MX9203630A (en)
NL (1) NL192111C (en)
NO (1) NO150515C (en)
SE (3) SE460198B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61140599A (en) * 1984-12-06 1986-06-27 バイオリサーチ・エス．ピー．エー Salt of 5'-methylthio-5'-deoxyadenosine and long chain alkylsulfonic acid
JPH0278621A (en) * 1988-07-29 1990-03-19 Bioresearch Spa Use of adenosine derivative in preparation of pharmaceutical composition having immunological stimulation activity
JP2008533107A (en) * 2005-03-17 2008-08-21 プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ Use of 5'-methylthioadenosine (MTA) in the prevention and / or treatment of autoimmune diseases and / or transplant rejection
WO2014163150A1 (en) * 2013-04-05 2014-10-09 ライオン株式会社 Composition for internal use
WO2014163152A1 (en) * 2013-04-05 2014-10-09 ライオン株式会社 Non-rem sleep-promoting agent, deep sleep-promoting agent and natural sleep-inducing agent

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0497287A (en) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd Picture display integrated circuit
ES2259552B1 (en) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. EMPLOYMENT OF 5'-METHYLTIOENENINE (MTA) IN THE PREVENTION AND / OR TREATMENT OF AUTOIMMUNE DISEASES AND / OR REPLACEMENT OF TRANSPLANTS.
DE102010027595A1 (en) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Clinical application of adenosine derivative, preferably (dihydroxyphenyl)ethyl-amino-purin-9-yl-(hydroxymethyl)oxolane-diol, for reducing body temperature during impending ischemia of brain vessels, which occur during heart attacks
DE102011005232A1 (en) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosine and its derivatives for use in pain therapy
JP6294870B2 (en) * 2013-04-05 2018-03-14 ライオン株式会社 Sleep-promoting agent comprising yeast culture as active ingredient, oral composition for promoting sleep, and food composition for promoting sleep

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125633A (en) * 1975-06-09 1977-10-21 Anvar Medicine based on adenosinee55 thioether
JPS54145222A (en) * 1978-04-28 1979-11-13 Merieux Inst Novel medicine * especially anodyne and sleep inducer and medical composition

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (en) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Process for the preparation of new 5'-sulfoxides of nucleosides
DE1545645A1 (en) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Process for the preparation of disubstituted adenosine derivatives
FR2252405B1 (en) * 1973-11-27 1978-04-28 Ajinomoto Kk

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52125633A (en) * 1975-06-09 1977-10-21 Anvar Medicine based on adenosinee55 thioether
JPS54145222A (en) * 1978-04-28 1979-11-13 Merieux Inst Novel medicine * especially anodyne and sleep inducer and medical composition

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61140599A (en) * 1984-12-06 1986-06-27 バイオリサーチ・エス．ピー．エー Salt of 5'-methylthio-5'-deoxyadenosine and long chain alkylsulfonic acid
JPH0160478B2 (en) * 1984-12-06 1989-12-22 Bioresearch Spa
JPH0278621A (en) * 1988-07-29 1990-03-19 Bioresearch Spa Use of adenosine derivative in preparation of pharmaceutical composition having immunological stimulation activity
JP2611003B2 (en) * 1988-07-29 1997-05-21 バイオリサーチ エス ピー エイ Immunostimulants
JP2008533107A (en) * 2005-03-17 2008-08-21 プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ Use of 5'-methylthioadenosine (MTA) in the prevention and / or treatment of autoimmune diseases and / or transplant rejection
WO2014163150A1 (en) * 2013-04-05 2014-10-09 ライオン株式会社 Composition for internal use
WO2014163152A1 (en) * 2013-04-05 2014-10-09 ライオン株式会社 Non-rem sleep-promoting agent, deep sleep-promoting agent and natural sleep-inducing agent
JPWO2014163152A1 (en) * 2013-04-05 2017-02-16 ライオン株式会社 Non-REM sleep promoter, deep sleep promoter and natural sleep inducer
JPWO2014163150A1 (en) * 2013-04-05 2017-02-16 ライオン株式会社 Oral composition

Also Published As

Publication number Publication date
GB8321947D0 (en) 1983-09-14
IT8021550A0 (en) 1980-04-22
NO150515B (en) 1984-07-23
GB2144409B (en) 1985-09-11
FR2491761B1 (en) 1984-01-06
FR2491761A1 (en) 1982-04-16
GB2144038B (en) 1985-08-29
MX9203630A (en) 1992-09-01
CH645544A5 (en) 1984-10-15
NL8101984A (en) 1981-11-16
ES8206551A1 (en) 1982-08-16
SE466238B (en) 1992-01-20
SE8700914L (en) 1987-03-04
SE464635B (en) 1991-05-27
JPH01301692A (en) 1989-12-05
DK176481A (en) 1981-10-23
FI811249L (en) 1981-10-23
CH650514A5 (en) 1985-07-31
LU83307A1 (en) 1981-07-24
SE8700913L (en) 1987-03-04
DE3116067A1 (en) 1982-03-11
GB8413454D0 (en) 1984-07-04
GB2074446B (en) 1985-04-11
ES8306378A1 (en) 1983-06-01
SE8700914D0 (en) 1987-03-04
FI70227C (en) 1986-09-15
FI70227B (en) 1986-02-28
NL192111C (en) 1997-02-04
AR231144A1 (en) 1984-09-28
JPH0249288B2 (en) 1990-10-29
CA1198105A (en) 1985-12-17
GB2074446A (en) 1981-11-04
IT1193529B (en) 1988-07-08
NO811346L (en) 1981-10-23
ES511039A0 (en) 1983-06-01
NL192111B (en) 1996-10-01
SE8102489L (en) 1981-10-23
ES501539A0 (en) 1982-08-16
GB2144038A (en) 1985-02-27
BE888472A (en) 1981-08-17
SE8700913D0 (en) 1987-03-04
NO150515C (en) 1984-10-31
DK159453B (en) 1990-10-15
JPH0246599B2 (en) 1990-10-16
SE460198B (en) 1989-09-18
GB2144409A (en) 1985-03-06
DE3116067C2 (en) 1992-12-17
DK159453C (en) 1991-03-18

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