JPS56140957A - Antibiotic mycoplanecin b, its derivative and preparation thereof - Google Patents

Antibiotic mycoplanecin b, its derivative and preparation thereof

Info

Publication number
JPS56140957A
JPS56140957A JP4540280A JP4540280A JPS56140957A JP S56140957 A JPS56140957 A JP S56140957A JP 4540280 A JP4540280 A JP 4540280A JP 4540280 A JP4540280 A JP 4540280A JP S56140957 A JPS56140957 A JP S56140957A
Authority
JP
Japan
Prior art keywords
methylvalyl
mycoplanecin
culture
ketobutyryl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4540280A
Other languages
Japanese (ja)
Other versions
JPS6312080B2 (en
Inventor
Mamoru Arai
Tatsuo Haishi
Mutsuo Nakajima
Akio Torigata
Ryuzo Enokida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP4540280A priority Critical patent/JPS56140957A/en
Priority to US06/250,709 priority patent/US4370266A/en
Priority to EP81301502A priority patent/EP0037736B1/en
Priority to AT81301502T priority patent/ATE3635T1/en
Priority to DE8181301502T priority patent/DE3160382D1/en
Publication of JPS56140957A publication Critical patent/JPS56140957A/en
Publication of JPS6312080B2 publication Critical patent/JPS6312080B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:The titled compound expressed by the formula (R is H, α-ketobutyryl-N-methylvalyl or α-hydroxy-butyryl-N-methylvalyl).
EXAMPLE: Mycoplanecin B (when R is α-ketobutyryl-N-methylvalyl).
USE: An antimicrobial agent capable of exhibiting a powerful activity against bacteria, particularly tubercle bacillus.
PROCESS: An actinomyces No.41042 strain, (FERM-P No.4504) belonging to the genus Actinoplanes is cultivated in a liquid culture medium by the shaking culture or spinner culture method with aeration. The pH of the culture medium is near neutral, and the temperature is about 28°C. The resultant culture is then filtered and centrifuged to give the compound of the formula.
COPYRIGHT: (C)1981,JPO&Japio
JP4540280A 1980-04-07 1980-04-07 Antibiotic mycoplanecin b, its derivative and preparation thereof Granted JPS56140957A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP4540280A JPS56140957A (en) 1980-04-07 1980-04-07 Antibiotic mycoplanecin b, its derivative and preparation thereof
US06/250,709 US4370266A (en) 1980-04-07 1981-04-03 Mycoplanecin derivatives and their preparation
EP81301502A EP0037736B1 (en) 1980-04-07 1981-04-07 Mycoplanecin derivatives, their preparation and pharmaceutical compositions containing them
AT81301502T ATE3635T1 (en) 1980-04-07 1981-04-07 MYCOPLANECIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
DE8181301502T DE3160382D1 (en) 1980-04-07 1981-04-07 Mycoplanecin derivatives, their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4540280A JPS56140957A (en) 1980-04-07 1980-04-07 Antibiotic mycoplanecin b, its derivative and preparation thereof

Publications (2)

Publication Number Publication Date
JPS56140957A true JPS56140957A (en) 1981-11-04
JPS6312080B2 JPS6312080B2 (en) 1988-03-17

Family

ID=12718254

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4540280A Granted JPS56140957A (en) 1980-04-07 1980-04-07 Antibiotic mycoplanecin b, its derivative and preparation thereof

Country Status (1)

Country Link
JP (1) JPS56140957A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58194848A (en) * 1982-05-11 1983-11-12 Sankyo Co Ltd Antibiotic, mycoplanesine d, its derivative and preparation thereof
US4596312A (en) * 1981-01-24 1986-06-24 Honda Giken Kogyo Kabushiki Kaisha Disc brake system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596312A (en) * 1981-01-24 1986-06-24 Honda Giken Kogyo Kabushiki Kaisha Disc brake system
JPS58194848A (en) * 1982-05-11 1983-11-12 Sankyo Co Ltd Antibiotic, mycoplanesine d, its derivative and preparation thereof
JPH0249717B2 (en) * 1982-05-11 1990-10-31 Sankyo Co

Also Published As

Publication number Publication date
JPS6312080B2 (en) 1988-03-17

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