JPS56140957A - Antibiotic mycoplanecin b, its derivative and preparation thereof - Google Patents
Antibiotic mycoplanecin b, its derivative and preparation thereofInfo
- Publication number
- JPS56140957A JPS56140957A JP4540280A JP4540280A JPS56140957A JP S56140957 A JPS56140957 A JP S56140957A JP 4540280 A JP4540280 A JP 4540280A JP 4540280 A JP4540280 A JP 4540280A JP S56140957 A JPS56140957 A JP S56140957A
- Authority
- JP
- Japan
- Prior art keywords
- methylvalyl
- mycoplanecin
- culture
- ketobutyryl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:The titled compound expressed by the formula (R is H, α-ketobutyryl-N-methylvalyl or α-hydroxy-butyryl-N-methylvalyl).
EXAMPLE: Mycoplanecin B (when R is α-ketobutyryl-N-methylvalyl).
USE: An antimicrobial agent capable of exhibiting a powerful activity against bacteria, particularly tubercle bacillus.
PROCESS: An actinomyces No.41042 strain, (FERM-P No.4504) belonging to the genus Actinoplanes is cultivated in a liquid culture medium by the shaking culture or spinner culture method with aeration. The pH of the culture medium is near neutral, and the temperature is about 28°C. The resultant culture is then filtered and centrifuged to give the compound of the formula.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4540280A JPS56140957A (en) | 1980-04-07 | 1980-04-07 | Antibiotic mycoplanecin b, its derivative and preparation thereof |
US06/250,709 US4370266A (en) | 1980-04-07 | 1981-04-03 | Mycoplanecin derivatives and their preparation |
EP81301502A EP0037736B1 (en) | 1980-04-07 | 1981-04-07 | Mycoplanecin derivatives, their preparation and pharmaceutical compositions containing them |
AT81301502T ATE3635T1 (en) | 1980-04-07 | 1981-04-07 | MYCOPLANECIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
DE8181301502T DE3160382D1 (en) | 1980-04-07 | 1981-04-07 | Mycoplanecin derivatives, their preparation and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4540280A JPS56140957A (en) | 1980-04-07 | 1980-04-07 | Antibiotic mycoplanecin b, its derivative and preparation thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56140957A true JPS56140957A (en) | 1981-11-04 |
JPS6312080B2 JPS6312080B2 (en) | 1988-03-17 |
Family
ID=12718254
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP4540280A Granted JPS56140957A (en) | 1980-04-07 | 1980-04-07 | Antibiotic mycoplanecin b, its derivative and preparation thereof |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56140957A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58194848A (en) * | 1982-05-11 | 1983-11-12 | Sankyo Co Ltd | Antibiotic, mycoplanesine d, its derivative and preparation thereof |
US4596312A (en) * | 1981-01-24 | 1986-06-24 | Honda Giken Kogyo Kabushiki Kaisha | Disc brake system |
-
1980
- 1980-04-07 JP JP4540280A patent/JPS56140957A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4596312A (en) * | 1981-01-24 | 1986-06-24 | Honda Giken Kogyo Kabushiki Kaisha | Disc brake system |
JPS58194848A (en) * | 1982-05-11 | 1983-11-12 | Sankyo Co Ltd | Antibiotic, mycoplanesine d, its derivative and preparation thereof |
JPH0249717B2 (en) * | 1982-05-11 | 1990-10-31 | Sankyo Co |
Also Published As
Publication number | Publication date |
---|---|
JPS6312080B2 (en) | 1988-03-17 |
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