JPS5612361A - Isopropylamine derivative and its preparation - Google Patents
Isopropylamine derivative and its preparationInfo
- Publication number
- JPS5612361A JPS5612361A JP8748879A JP8748879A JPS5612361A JP S5612361 A JPS5612361 A JP S5612361A JP 8748879 A JP8748879 A JP 8748879A JP 8748879 A JP8748879 A JP 8748879A JP S5612361 A JPS5612361 A JP S5612361A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- isopropylamine
- derivative
- reacted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:An isopropylamine derivative shown by the formula I (R is H or alkyl) and a 1,2-epoxypropane derivative shown by the formula II.
EXAMPLE: 1-Isopropylamino-2-hydroxy-3-[ 2-( 4-methylphenylsulfonyloxy )-phenoxy]-propane.
USE: A synthetic intermediate for a β-adrenergic neuromal blocking agent. A compound shown by the formula III useful as a remedy for arrhythmia, angina pectoris, etc. can be obtained in mild conditions efficiently from a compound shown by the formula I.
PROCESS: A compound shown by the formula IV is reacted with a compound shown by the formula V in the presence of a deoxygenizer (e.g., NaOH, etc.) to give a compound shown by the formula II, which is reacted with isopropylamine preferably in the presence of a small amount of water to give a compound shown by the formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8748879A JPS5612361A (en) | 1979-07-12 | 1979-07-12 | Isopropylamine derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8748879A JPS5612361A (en) | 1979-07-12 | 1979-07-12 | Isopropylamine derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5612361A true JPS5612361A (en) | 1981-02-06 |
JPS6126902B2 JPS6126902B2 (en) | 1986-06-23 |
Family
ID=13916327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8748879A Granted JPS5612361A (en) | 1979-07-12 | 1979-07-12 | Isopropylamine derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5612361A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6095944A (en) * | 1983-10-31 | 1985-05-29 | Ibiden Co Ltd | Plug-in package and manufacture thereof |
JPS6095943A (en) * | 1983-10-31 | 1985-05-29 | Ibiden Co Ltd | Plug-in package and manufacture thereof |
-
1979
- 1979-07-12 JP JP8748879A patent/JPS5612361A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6095944A (en) * | 1983-10-31 | 1985-05-29 | Ibiden Co Ltd | Plug-in package and manufacture thereof |
JPS6095943A (en) * | 1983-10-31 | 1985-05-29 | Ibiden Co Ltd | Plug-in package and manufacture thereof |
JPH0582060B2 (en) * | 1983-10-31 | 1993-11-17 | Ibiden Co Ltd |
Also Published As
Publication number | Publication date |
---|---|
JPS6126902B2 (en) | 1986-06-23 |
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