JPS5549363A - Production of 4(r)-thiazolidinecarboxylic acid derivative - Google Patents
Production of 4(r)-thiazolidinecarboxylic acid derivativeInfo
- Publication number
- JPS5549363A JPS5549363A JP12372478A JP12372478A JPS5549363A JP S5549363 A JPS5549363 A JP S5549363A JP 12372478 A JP12372478 A JP 12372478A JP 12372478 A JP12372478 A JP 12372478A JP S5549363 A JPS5549363 A JP S5549363A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- acid
- thiazolidinecarboxylic acid
- compound
- thiazolidinecarboxylic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
Abstract
PURPOSE: The hydrolysis of a specific compound resulting from reaction between a carboxylic acid or its derivative and 4(R)-thiazolidinecarboxylic acid gives title compound that has the activity inhibiting angiotensin-transforming enzyme and is used as antihypertensive.
CONSTITUTION: A compound of formula I (R is R'OCO, R'OCS, R'NHCS; R' is alkyl, phenyl) is subjected to hydrolysis in a solvent to give 3-(3-mercapto-2-methylpropionyl)-4(R)-thiazolidinecarboxylic acid. The compound of formula I is obtained by reaction of a carboxylic acid of formula III or its reactive derivative and 4(R)- thizaoldinecarboxylic acid of formula IV, and an example is 3-{3-[(methyl)thiocarbamoylthio]-2(S)-methylpropionyl}-4(R)-thiazolidinecarboxylic acid.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12372478A JPS5549363A (en) | 1978-10-06 | 1978-10-06 | Production of 4(r)-thiazolidinecarboxylic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12372478A JPS5549363A (en) | 1978-10-06 | 1978-10-06 | Production of 4(r)-thiazolidinecarboxylic acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5549363A true JPS5549363A (en) | 1980-04-09 |
Family
ID=14867785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12372478A Pending JPS5549363A (en) | 1978-10-06 | 1978-10-06 | Production of 4(r)-thiazolidinecarboxylic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5549363A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6271485A (en) * | 1985-09-20 | 1987-04-02 | Sony Corp | Brushless motor |
-
1978
- 1978-10-06 JP JP12372478A patent/JPS5549363A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6271485A (en) * | 1985-09-20 | 1987-04-02 | Sony Corp | Brushless motor |
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