JPS5527109A - 4-formyl-1-phthalazone derivative - Google Patents

4-formyl-1-phthalazone derivative

Info

Publication number
JPS5527109A
JPS5527109A JP9827178A JP9827178A JPS5527109A JP S5527109 A JPS5527109 A JP S5527109A JP 9827178 A JP9827178 A JP 9827178A JP 9827178 A JP9827178 A JP 9827178A JP S5527109 A JPS5527109 A JP S5527109A
Authority
JP
Japan
Prior art keywords
phthalazone
formyl
alkyl
compound
new material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP9827178A
Other languages
Japanese (ja)
Inventor
Masayuki Ishikawa
Masao Eguchi
Hiromichi Tanaka
Shigeru Ito
Yoshimi Takashima
Masahiko Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP9827178A priority Critical patent/JPS5527109A/en
Publication of JPS5527109A publication Critical patent/JPS5527109A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A 4-formyl-1-phthalazone derivative I (R1 and R2 are lower alkyl; R3 is alkyl; R4 is H, halogen, alkyl or alkoxy; R5 is halogen, alkyl, alkoxy, alkoxycarbonyl or caboxyl).
EXAMPLE: 7-Ethoxycarbonyl-6,8-dimethyl-4-formyl-2-(p-chlorophenyl)-1-phthalazone.
USE: Remedies for arteriosclerosis, thrombosis and thrombokisan, and intermediates for the synthesis of 7-ethoxycarbonyl-6,8-dimethyl-4-(β,β-diacetylvinyl)-2-substituted phenyl-1-phthalazone and its derivatives.
PROCESS: A compound I is prepared by oxidizing a compound III (a new material) with an oxidizing agent, e.g. N-bromosuccinic imide, etc.. The new material III is prepared by reducing a reactive derivative of the corresponding 4-carboxylic acid compound with a boron hydride complex compound in a solvent.
COPYRIGHT: (C)1980,JPO&Japio
JP9827178A 1978-08-14 1978-08-14 4-formyl-1-phthalazone derivative Pending JPS5527109A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9827178A JPS5527109A (en) 1978-08-14 1978-08-14 4-formyl-1-phthalazone derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9827178A JPS5527109A (en) 1978-08-14 1978-08-14 4-formyl-1-phthalazone derivative

Publications (1)

Publication Number Publication Date
JPS5527109A true JPS5527109A (en) 1980-02-27

Family

ID=14215268

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9827178A Pending JPS5527109A (en) 1978-08-14 1978-08-14 4-formyl-1-phthalazone derivative

Country Status (1)

Country Link
JP (1) JPS5527109A (en)

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