JPS5515435A - Blood platelet coagulation suppressing agent - Google Patents
Blood platelet coagulation suppressing agentInfo
- Publication number
- JPS5515435A JPS5515435A JP8775078A JP8775078A JPS5515435A JP S5515435 A JPS5515435 A JP S5515435A JP 8775078 A JP8775078 A JP 8775078A JP 8775078 A JP8775078 A JP 8775078A JP S5515435 A JPS5515435 A JP S5515435A
- Authority
- JP
- Japan
- Prior art keywords
- sulfuric acid
- sodium salt
- acid sodium
- glucan
- blood platelet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To provide an agent for suppressing the coagulation of blood platelet, having higher activity than the conventional heparin preparation, and containing a specific glucan sulfuric acid sodium salt as an active component.
CONSTITUTION: The title agent containing a glucan sulfuric acid sodium salt composed mainly of α-1,4 bond, and pref. having an intrinsic viscosity of 0.010W1.50 and a sulfur content of 5W21.0 wt% (e.g. amylopectin sulfuric acid sodium salt, amylose sulfuric acid sodium salt, glycogen sulfuric acid sodium salt, etc.) as an active component. The glucan sulfuric acid sodium salt can be prepared by reacting glucan with pasty concentrated sulfuric acid at low temperature, neutralizing the reaction product with sodium carbonate, etc., and adding an alcohol to the reaction mixture to precipitate the objective compound.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8775078A JPS5515435A (en) | 1978-07-20 | 1978-07-20 | Blood platelet coagulation suppressing agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8775078A JPS5515435A (en) | 1978-07-20 | 1978-07-20 | Blood platelet coagulation suppressing agent |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5515435A true JPS5515435A (en) | 1980-02-02 |
Family
ID=13923603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8775078A Pending JPS5515435A (en) | 1978-07-20 | 1978-07-20 | Blood platelet coagulation suppressing agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5515435A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5017565A (en) * | 1989-04-20 | 1991-05-21 | Lange Iii Louis G | Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase |
US5063210A (en) * | 1989-04-20 | 1991-11-05 | Lange Iii Louis G | Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption |
US5484777A (en) * | 1989-04-20 | 1996-01-16 | Lange, Iii; Louis G. | Pancreatic cholesterol esterase inhibitor |
US6632801B1 (en) | 1994-10-13 | 2003-10-14 | Cv Therapeutics, Inc. | Method and composition for inhibiting human cholesterol esterase |
-
1978
- 1978-07-20 JP JP8775078A patent/JPS5515435A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5017565A (en) * | 1989-04-20 | 1991-05-21 | Lange Iii Louis G | Use of sulfated polysaccharides to inhibit pancreatic cholesterol esterase |
US5063210A (en) * | 1989-04-20 | 1991-11-05 | Lange Iii Louis G | Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption |
US5484777A (en) * | 1989-04-20 | 1996-01-16 | Lange, Iii; Louis G. | Pancreatic cholesterol esterase inhibitor |
US6632801B1 (en) | 1994-10-13 | 2003-10-14 | Cv Therapeutics, Inc. | Method and composition for inhibiting human cholesterol esterase |
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