JPS55122783A - Preparation of porfiromycin derivative - Google Patents

Preparation of porfiromycin derivative

Info

Publication number
JPS55122783A
JPS55122783A JP2825079A JP2825079A JPS55122783A JP S55122783 A JPS55122783 A JP S55122783A JP 2825079 A JP2825079 A JP 2825079A JP 2825079 A JP2825079 A JP 2825079A JP S55122783 A JPS55122783 A JP S55122783A
Authority
JP
Japan
Prior art keywords
decarbamoyloxy
porfiromycin
derivative
preparation
dehydroporfiromycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2825079A
Other languages
Japanese (ja)
Inventor
Masaji Kasai
Kazumichi Kono
Kimikatsu Shirahata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP2825079A priority Critical patent/JPS55122783A/en
Priority to DE7979102497T priority patent/DE2966984D1/en
Priority to EP79102497A priority patent/EP0008021B1/en
Priority to US06/126,346 priority patent/US4374774A/en
Publication of JPS55122783A publication Critical patent/JPS55122783A/en
Pending legal-status Critical Current

Links

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  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PURPOSE: To prepare the title compound having antibacterial activity, by converting the 7-position amino group of 10-decarbamoyloxy-9-dehydroporfiromycin to OH group by alkali hydrolysis, and then reacting the product with an alkylating agent.
CONSTITUTION: 10-Decarbamoyloxy-9-dehydro-7-deamino-7-hydroxyporfiromycin II obtained by the alkali hydrolysis of 10-decarbamoyloxy-9-dehydroporfiromycin, is reacted with an alkylating agent (pref. diazoalkane) to obtain 10-decarbamoyloxy- 9-dehydro-7-deamino-7-alkoxyporfiromycin I (R is alkyl).
COPYRIGHT: (C)1980,JPO&Japio
JP2825079A 1978-07-18 1979-03-13 Preparation of porfiromycin derivative Pending JPS55122783A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2825079A JPS55122783A (en) 1979-03-13 1979-03-13 Preparation of porfiromycin derivative
DE7979102497T DE2966984D1 (en) 1978-07-18 1979-07-17 New mitomycins and processes for production thereof
EP79102497A EP0008021B1 (en) 1978-07-18 1979-07-17 New mitomycins and processes for production thereof
US06/126,346 US4374774A (en) 1979-03-13 1980-03-03 Mitomycins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2825079A JPS55122783A (en) 1979-03-13 1979-03-13 Preparation of porfiromycin derivative

Publications (1)

Publication Number Publication Date
JPS55122783A true JPS55122783A (en) 1980-09-20

Family

ID=12243323

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2825079A Pending JPS55122783A (en) 1978-07-18 1979-03-13 Preparation of porfiromycin derivative

Country Status (1)

Country Link
JP (1) JPS55122783A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4776894A (en) * 1986-08-18 1988-10-11 Sanyo Electric Co., Ltd. Photovoltaic device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4776894A (en) * 1986-08-18 1988-10-11 Sanyo Electric Co., Ltd. Photovoltaic device

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