JPS55120786A - Variant capable of producing anthracycline glycoside - Google Patents

Variant capable of producing anthracycline glycoside

Info

Publication number
JPS55120786A
JPS55120786A JP2982079A JP2982079A JPS55120786A JP S55120786 A JPS55120786 A JP S55120786A JP 2982079 A JP2982079 A JP 2982079A JP 2982079 A JP2982079 A JP 2982079A JP S55120786 A JPS55120786 A JP S55120786A
Authority
JP
Japan
Prior art keywords
producing
glycoside
variant
anthracycline
anthracycline glycoside
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2982079A
Other languages
Japanese (ja)
Inventor
Shunichi Oki
Akihiro Yoshimoto
Taiji Inui
Tomio Takeuchi
Hamao Umezawa
Kageaki Kono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanraku Inc
Sanraku Ocean Co Ltd
Original Assignee
Sanraku Inc
Sanraku Ocean Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanraku Inc, Sanraku Ocean Co Ltd filed Critical Sanraku Inc
Priority to JP2982079A priority Critical patent/JPS55120786A/en
Publication of JPS55120786A publication Critical patent/JPS55120786A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PURPOSE:A novel variant KE-303 capable of producing anthracycline.glycoside, preparation of the variant, and preparation of anthracycline-glycoside using the same. CONSTITUTION:An aclacinomycin-producing strain, Streptomyces galilaeus MA- 144-MI (FERM-P No.2455) is subjected to a conventional mutagenic treatment, e.g. the NTG treatment, to obtain a novel variant KE-303 strain (FERM-P No.4808) lack in anthracyline pigment-producing capability and capable of producing anthracycline.glycoside from anthracyclinone. The variant is inoculated in a nutrient medium containing anthracyclinone, and cultured to accumulate the objective anthracycline-glycoside in the medium.
JP2982079A 1979-03-14 1979-03-14 Variant capable of producing anthracycline glycoside Pending JPS55120786A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2982079A JPS55120786A (en) 1979-03-14 1979-03-14 Variant capable of producing anthracycline glycoside

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2982079A JPS55120786A (en) 1979-03-14 1979-03-14 Variant capable of producing anthracycline glycoside

Publications (1)

Publication Number Publication Date
JPS55120786A true JPS55120786A (en) 1980-09-17

Family

ID=12286652

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2982079A Pending JPS55120786A (en) 1979-03-14 1979-03-14 Variant capable of producing anthracycline glycoside

Country Status (1)

Country Link
JP (1) JPS55120786A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6036437A (en) * 1983-06-25 1985-02-25 ヘキスト・アクチエンゲゼルシヤフト Anthracycline derivative and manufacture

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6036437A (en) * 1983-06-25 1985-02-25 ヘキスト・アクチエンゲゼルシヤフト Anthracycline derivative and manufacture

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