JPS54143490A - Preparation of polymer composition - Google Patents
Preparation of polymer compositionInfo
- Publication number
- JPS54143490A JPS54143490A JP5123978A JP5123978A JPS54143490A JP S54143490 A JPS54143490 A JP S54143490A JP 5123978 A JP5123978 A JP 5123978A JP 5123978 A JP5123978 A JP 5123978A JP S54143490 A JPS54143490 A JP S54143490A
- Authority
- JP
- Japan
- Prior art keywords
- active substance
- physiologically active
- low temperature
- polymer
- vitrifiable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicinal Preparation (AREA)
- Polymerisation Methods In General (AREA)
Abstract
PURPOSE: To prepare a polymer composition useful as chemicals, etc., capable of slowly releasing a physiologically active substance, by radiation polymerization of a mixture of a monomer vitrifiable at a low temperature the physiologically active substance, and a polymeric material, at low temperatures.
CONSTITUTION: The mixture comprising (A) 5W50 wt.% of a natural or synthetic polymeric material (e.g. polymethyl methacrylate, etc.), (B) a monomer vitrifiable at a low temperature (e.g. hydroxyethyl methacrylate, etc.) and (C) a physiologically active substance (e.g. chemicals such as bleomycin hydrochloride, etc,), is dropped or injected into a low temperature-medium to form spherical droplets, and polymerized by radiating light or ionizing radiations below ordinary temperature to give the desired polymer. The polymer is preferably spheres having a size of 50W 5,000 μ.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5123978A JPS588402B2 (en) | 1978-04-28 | 1978-04-28 | Method for producing polymer composition |
CA322,930A CA1125698A (en) | 1978-03-09 | 1979-03-07 | Process for preparing a polymer composition |
DE2908794A DE2908794C2 (en) | 1978-03-09 | 1979-03-07 | Process for the production of a polymer preparation containing a physiologically active substance |
GB7908163A GB2017113B (en) | 1978-03-09 | 1979-03-08 | Process for preparing a composition of a polymer and a physiologically active substance |
IT7967493A IT7967493A0 (en) | 1978-03-09 | 1979-03-08 | PROCEDURE FOR THE PREPARATION OF A POLYMER COMPOSITION |
ES478446A ES478446A1 (en) | 1978-03-09 | 1979-03-08 | Process for preparing a polymer composition |
US06/018,617 US4321117A (en) | 1978-03-09 | 1979-03-08 | Process for preparing a polymer composition |
FR7905982A FR2419299A1 (en) | 1978-03-09 | 1979-03-08 | PROCESS FOR MANUFACTURING A POLYMERIC COMPOSITION CONTAINING A PHYSIOLOGICALLY ACTIVE SUBSTANCE |
SE7902166A SE7902166L (en) | 1978-03-09 | 1979-03-09 | PROCEDURE FOR PREPARING A POLYMER COMPOSITION |
NL7901919A NL7901919A (en) | 1978-03-09 | 1979-03-09 | Polymer compsn. contg. physiologically active cpd. - with controlled release mixt., prepd. by polymerising monomers with radiation at below room temp. (NL 11.9.79) |
US06/234,839 US4411754A (en) | 1978-03-09 | 1981-02-13 | Process for preparing a polymer composition |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5123978A JPS588402B2 (en) | 1978-04-28 | 1978-04-28 | Method for producing polymer composition |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS54143490A true JPS54143490A (en) | 1979-11-08 |
JPS588402B2 JPS588402B2 (en) | 1983-02-16 |
Family
ID=12881382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5123978A Expired JPS588402B2 (en) | 1978-03-09 | 1978-04-28 | Method for producing polymer composition |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS588402B2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58144314A (en) * | 1982-02-19 | 1983-08-27 | Japan Atom Energy Res Inst | Preparation of combined substance having prolonged effect |
JPS60231609A (en) * | 1984-04-28 | 1985-11-18 | Terumo Corp | Liposome pharmaceutical |
-
1978
- 1978-04-28 JP JP5123978A patent/JPS588402B2/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58144314A (en) * | 1982-02-19 | 1983-08-27 | Japan Atom Energy Res Inst | Preparation of combined substance having prolonged effect |
JPS6351127B2 (en) * | 1982-02-19 | 1988-10-13 | Japan Atomic Energy Res Inst | |
JPS60231609A (en) * | 1984-04-28 | 1985-11-18 | Terumo Corp | Liposome pharmaceutical |
Also Published As
Publication number | Publication date |
---|---|
JPS588402B2 (en) | 1983-02-16 |
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