JPS5412461B2 - - Google Patents

Info

Publication number
JPS5412461B2
JPS5412461B2 JP14586074A JP14586074A JPS5412461B2 JP S5412461 B2 JPS5412461 B2 JP S5412461B2 JP 14586074 A JP14586074 A JP 14586074A JP 14586074 A JP14586074 A JP 14586074A JP S5412461 B2 JPS5412461 B2 JP S5412461B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP14586074A
Other versions
JPS5095246A (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS5095246A publication Critical patent/JPS5095246A/ja
Publication of JPS5412461B2 publication Critical patent/JPS5412461B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP14586074A 1973-12-20 1974-12-20 Expired JPS5412461B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1066673A AT334385B (de) 1973-12-20 1973-12-20 Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Publications (2)

Publication Number Publication Date
JPS5095246A JPS5095246A (ja) 1975-07-29
JPS5412461B2 true JPS5412461B2 (ja) 1979-05-23

Family

ID=3623884

Family Applications (2)

Application Number Title Priority Date Filing Date
JP14586074A Expired JPS5412461B2 (ja) 1973-12-20 1974-12-20
JP3982678A Granted JPS53149947A (en) 1973-12-20 1978-04-06 New derivative of phenoxypropylamine and method for production of its salt

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP3982678A Granted JPS53149947A (en) 1973-12-20 1978-04-06 New derivative of phenoxypropylamine and method for production of its salt

Country Status (19)

Country Link
US (1) US4034009A (ja)
JP (2) JPS5412461B2 (ja)
AT (1) AT334385B (ja)
BE (1) BE823411A (ja)
CA (1) CA1001626A (ja)
CH (1) CH612417A5 (ja)
CS (1) CS185669B2 (ja)
DD (1) DD118421A1 (ja)
ES (1) ES433145A1 (ja)
FR (1) FR2255058B1 (ja)
GB (1) GB1441359A (ja)
IE (1) IE40310B1 (ja)
IL (1) IL46259A (ja)
LU (2) LU71514A1 (ja)
PL (1) PL94095B1 (ja)
RO (1) RO69147A (ja)
SU (1) SU547174A3 (ja)
YU (1) YU36492B (ja)
ZA (1) ZA748067B (ja)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177280A (en) * 1978-07-03 1979-12-04 Syntex (U.S.A.) Inc. Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents
JPS5757231U (ja) * 1980-09-19 1982-04-03
US4470965A (en) * 1982-10-27 1984-09-11 Usv Pharmaceutical Corporation Celiprolol for the treatment of glaucoma
JPS60164639A (ja) * 1984-02-07 1985-08-27 Hitachi Ltd 燃料噴射弁の駆動制御装置
DE3410380A1 (de) * 1984-03-21 1985-10-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
DE3636209A1 (de) * 1986-10-24 1988-04-28 Lentia Gmbh Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates
CN1681495B (zh) 2002-08-19 2010-05-12 辉瑞产品公司 用于治疗过度增生性疾病的组合物
CA2526730A1 (en) * 2003-05-30 2004-12-09 Ranbaxy Laboratories Limited Substituted pyrrole derivatives
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
WO2007029155A2 (en) * 2005-09-05 2007-03-15 Ranbaxy Laboratories Limited An improved process for preparation of pure celiprolol base
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
SG166829A1 (en) * 2005-11-08 2010-12-29 Ranbaxy Lab Ltd Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
AR059838A1 (es) * 2006-03-14 2008-04-30 Ranbaxy Lab Ltd Formulaciones para dosis estabilizantes de estatina
BRPI0714361A2 (pt) * 2006-07-14 2013-03-26 Ranbaxy Lab Ltd polimorfo cristalino, composiÇço farmacÊutica contendo o mesmo, mÉtodo para sua preparaÇço e mÉtodo de tratamento
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2170930B3 (en) 2007-06-04 2013-10-02 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8987262B2 (en) 2007-10-19 2015-03-24 Universite de Bordeaux Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
EP2050441A1 (en) * 2007-10-19 2009-04-22 Université Victor Segalen Bordeaux 2 Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
EP3004138B1 (en) 2013-06-05 2024-03-13 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EP3911648A4 (en) 2019-01-18 2022-10-26 Astrazeneca AB PCSK9 INHIBITORS AND METHODS OF USE THEREOF

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1214012A (en) * 1967-12-21 1970-11-25 Allen & Hanburys Ltd Phenylethanolamines
AT292671B (de) * 1967-12-22 1971-09-10 May & Baker Ltd Verfahren zur Herstellung von neuen 3-(4'-Alkanoylamino-2'-acylphenoxy)-2-hydroxy-1-aminopropanen
US3935259A (en) * 1970-01-08 1976-01-27 Ciba-Geigy Corporation New amines and processes for their manufacture
SE354851B (ja) * 1970-02-18 1973-03-26 Haessle Ab
NL7115581A (ja) * 1970-11-13 1972-05-16 Dresden Arzneimittel
GB1396322A (en) * 1971-06-15 1975-06-04 Ici Ltd Alkanolamine derivatives
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen
GB1460593A (en) * 1973-06-22 1977-01-06 Ici Ltd Ethanolamine derivatives
FI65987C (fi) * 1973-12-12 1984-08-10 Ici Ltd Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
AT334386B (de) * 1973-12-21 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Also Published As

Publication number Publication date
DD118421A1 (ja) 1976-03-05
LU71514A1 (ja) 1975-08-20
FR2255058A1 (ja) 1975-07-18
IL46259A0 (en) 1975-03-13
IL46259A (en) 1978-04-30
CS185669B2 (en) 1978-10-31
RO69147A (ro) 1981-07-30
ATA1066673A (de) 1976-05-15
FR2255058B1 (ja) 1978-07-28
GB1441359A (en) 1976-06-30
BE823411A (fr) 1975-06-16
AU7653874A (en) 1976-06-17
IE40310L (en) 1975-06-20
JPS5549071B2 (ja) 1980-12-10
YU36492B (en) 1984-02-29
JPS5095246A (ja) 1975-07-29
SU547174A3 (ru) 1977-02-15
YU327774A (en) 1982-02-25
LU88296I2 (fr) 1994-05-04
AT334385B (de) 1976-01-10
ES433145A1 (es) 1976-11-16
PL94095B1 (ja) 1977-07-30
US4034009A (en) 1977-07-05
CH612417A5 (ja) 1979-07-31
CA1001626A (en) 1976-12-14
ZA748067B (en) 1976-01-28
IE40310B1 (en) 1979-04-25
JPS53149947A (en) 1978-12-27

Similar Documents

Publication Publication Date Title
AR201758A1 (ja)
AR201235Q (ja)
AR201231Q (ja)
FR2255058B1 (ja)
AU465453B2 (ja)
AR201229Q (ja)
AR199451A1 (ja)
AR200885A1 (ja)
AR200256A1 (ja)
AR197627A1 (ja)
AR196382A1 (ja)
AR195948A1 (ja)
AR195311A1 (ja)
AR201432A1 (ja)
AR193950A1 (ja)
AR210729A1 (ja)
AR196212Q (ja)
AR196123Q (ja)
CH566651A5 (ja)
BG26948A3 (ja)
CH564837A5 (ja)
CH563914A5 (ja)
CH562645A5 (ja)
CH561905A5 (ja)
CH559658A5 (ja)