JPS5335065B2 - - Google Patents

Info

Publication number: JPS5335065B2
Authority: JP; Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP744666A

Other versions

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-01-02

Filing date

1973-12-28

Publication date

1978-09-25

1973-01-02 Priority claimed from AT173A external-priority patent/AT319915B/de

1973-12-28 Application filed filed Critical

1974-09-20 Publication of JPS49100043A publication Critical patent/JPS49100043A/ja

1978-09-25 Publication of JPS5335065B2 publication Critical patent/JPS5335065B2/ja

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/26—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C219/28—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Hematology (AREA)
Pulmonology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

JP744666A 1973-01-02 1973-12-28 Expired JPS5335065B2 (ja)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
AT173A AT319915B (de)	1973-01-02	1973-01-02	Verfahren zur Herstellung von neuen 2-Aminomethyl-4,6-dihalogenphenolderivaten sowie deren Salzen mit physiologisch verträglichen Säuren oder Basen
AT738773A AT332863B (de)	1973-01-02	1973-08-24	Verfahren zur herstellung von neuen 2-aminomethyl-4,6-dihalogenphenolderivaten sowie deren additionssalzen mit sauren
BE152177A BE824138R (fr)	1973-01-02	1975-01-06	Procede de preparation de nouveaux derives d'aminomethyl-2 dihalo-4,6-phenol
BE824138		1975-01-06

Publications (2)

Publication Number	Publication Date
JPS49100043A JPS49100043A (ja)	1974-09-20
JPS5335065B2 true JPS5335065B2 (ja)	1978-09-25

Family

ID=27421065

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP744666A Expired JPS5335065B2 (ja)	1973-01-02	1973-12-28

Country Status (16)

Country	Link
US (1)	US3996278A (ja)
JP (1)	JPS5335065B2 (ja)
AT (1)	AT332863B (ja)
BE (1)	BE824138R (ja)
BG (1)	BG24226A3 (ja)
CA (1)	CA1090340A (ja)
CH (1)	CH610292A5 (ja)
CS (1)	CS183634B2 (ja)
DD (1)	DD113526A5 (ja)
DE (1)	DE2364191C2 (ja)
DK (1)	DK309774A (ja)
FR (1)	FR2212145B1 (ja)
GB (1)	GB1460761A (ja)
NL (1)	NL167414C (ja)
SE (1)	SE420716B (ja)
SU (1)	SU1091852A3 (ja)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2287219A2 (fr) *	1974-10-11	1976-05-07	Gerot Pharmazeutika	Nouveaux derives 2-aminomethyl-4,6-dinalophenoliques et leur procede de preparation
DE2934508A1 (de) *	1978-09-06	1980-03-20	Sandoz Ag	Alpha -alkyl-o-oxybenzylamin- derivate, ihre herstellung und sie enthaltende heilmittel
US4578390A (en) *	1981-12-14	1986-03-25	Merck & Co., Inc.	Hydroxybenzylamino derivatives as anti-inflammatory agents
CA1219587A (en) *	1981-12-14	1987-03-24	Norman P. Jensen	Hydroxybenzylaminobenzenes as anti-inflammatory agents
FR2661176B1 (fr) *	1990-04-20	1992-06-12	Adir	Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
ZA923283B (en) *	1991-05-29	1993-01-27	Akzo Nv	Phenoxyphenyl derivatives
CA2543913A1 (en) *	2003-11-10	2005-05-26	Schering Aktiengesellschaft	Benzylether amine compounds useful as ccr-5 antagonists
CN103833588B (zh) *	2012-11-16	2015-09-23	上海医药工业研究院	酰胺类化合物的两种晶型、制备方法及其应用
CN113214097B (zh) *	2020-01-21	2022-08-30	厦门大学	治疗阿尔茨海默病的化合物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS4972224A (ja) *	1972-10-23	1974-07-12

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2806063A (en) *	1956-04-23	1957-09-10	Dow Chemical Co	Amine salts of chlorophenols
BE562425A (ja)	1956-11-16
US3227756A (en) *	1962-07-10	1966-01-04	Velsicol Chemical Corp	N,n-mono- and di-substituted-aralkyl amines
US3809721A (en) *	1970-12-23	1974-05-07	Merck & Co Inc	Substituted 2-aminomethyl-4,6-disubstituted phenols
US3864401A (en)	1970-12-23	1975-02-04	Merck & Co Inc	Substituted 2-aminomethyl-4,6-dihalophenols

1973
- 1973-08-24 AT AT738773A patent/AT332863B/de not_active IP Right Cessation
- 1973-12-20 SE SE7317226A patent/SE420716B/xx unknown
- 1973-12-21 DE DE2364191A patent/DE2364191C2/de not_active Expired
- 1973-12-27 FR FR7346569A patent/FR2212145B1/fr not_active Expired
- 1973-12-28 NL NL7317753.A patent/NL167414C/xx not_active IP Right Cessation
- 1973-12-28 JP JP744666A patent/JPS5335065B2/ja not_active Expired
- 1973-12-29 CH CH1828073A patent/CH610292A5/xx not_active IP Right Cessation
1974
- 1974-01-02 SU SU741993871D patent/SU1091852A3/ru active
- 1974-01-02 GB GB14174A patent/GB1460761A/en not_active Expired
- 1974-01-02 US US05/429,984 patent/US3996278A/en not_active Expired - Lifetime
- 1974-06-10 DK DK309774A patent/DK309774A/da not_active Application Discontinuation
- 1974-06-12 BG BG7400026944A patent/BG24226A3/xx unknown
- 1974-06-19 DD DD179285A patent/DD113526A5/xx unknown
- 1974-06-26 CA CA203,513A patent/CA1090340A/en not_active Expired
- 1974-07-10 CS CS7400004925A patent/CS183634B2/cs unknown
1975
- 1975-01-06 BE BE152177A patent/BE824138R/xx not_active IP Right Cessation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS4972224A (ja) *	1972-10-23	1974-07-12

Also Published As

Publication number	Publication date
DE2364191A1 (de)	1974-07-11
DK309774A (ja)	1975-04-28
FR2212145B1 (ja)	1977-01-28
DE2364191C2 (de)	1986-06-12
BE824138R (fr)	1975-07-07
SE420716B (sv)	1981-10-26
FR2212145A1 (ja)	1974-07-26
CS183634B2 (en)	1978-07-31
CA1090340A (en)	1980-11-25
DD113526A5 (ja)	1975-06-12
NL167414B (nl)	1981-07-16
NL7317753A (ja)	1974-07-04
BG24226A3 (en)	1978-01-10
AU7087774A (en)	1976-01-08
US3996278A (en)	1976-12-07
ATA738773A (de)	1976-02-15
CH610292A5 (ja)	1979-04-12
JPS49100043A (ja)	1974-09-20
GB1460761A (en)	1977-01-06
NL167414C (nl)	1981-12-16
AT332863B (de)	1976-10-25
SU1091852A3 (ru)	1984-05-07

Publication	Publication Date	Title
AR201758A1 (ja)	1975-04-15
AU476761B2 (ja)	1976-09-30
AR201235Q (ja)	1975-02-21
AR201231Q (ja)	1975-02-21
AU474593B2 (ja)	1976-07-29
AU474511B2 (ja)	1976-07-22
AU474838B2 (ja)	1976-08-05
AU465453B2 (ja)	1975-09-25
AU471343B2 (ja)	1976-04-15
AU465434B2 (ja)	1975-09-25
AU450229B2 (ja)	1974-07-04
AU476714B2 (ja)	1976-09-30
FR2212145A1 (ja)	1974-07-26
AR201229Q (ja)	1975-02-21
AU466283B2 (ja)	1975-10-23
AU476696B2 (ja)	1976-09-30
AU472848B2 (ja)	1976-06-03
AR199451A1 (ja)	1974-08-30
AU477823B2 (ja)	1975-06-19
AU461342B2 (ja)	1975-05-22
AU471461B2 (ja)	1976-04-29
AR200256A1 (ja)	1974-10-31
AU476873B1 (ja)	1975-01-09
AR210729A1 (ja)	1977-09-15
AU477824B2 (ja)	1975-07-17